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The map label for this gene is pgl [H]

Identifier: 110679936

GI number: 110679936

Start: 2592406

End: 2593077

Strand: Reverse

Name: pgl [H]

Synonym: RD1_2721

Alternate gene names: 110679936

Gene position: 2593077-2592406 (Counterclockwise)

Preceding gene: 110679937

Following gene: 110679935

Centisome position: 62.74

GC content: 62.35

Gene sequence:

>672_bases
ATGCAAATCATTGAGTATATCGACCGGGATCTTGCGGCCATTGGCGTGGCCGACACGCTGGCCAGCGGGTTGAAAAAAGC
GCTGTCGATACAGGAAAGGGTCAGCCTCGCCGTGCCGGGAGGCACAACGCCGGGGCCGATTTTTGACGTGCTCAGCGCCG
CCGTGCTGGACTGGGACCGCGTGACGATCATGCTGACGGATGAACGCTGGGTGCCGGAGGACCACGCGCGTTCAAATGCG
GCCTTGATCAGATCGCGGCTGATGCAGGGGCCCGCCGCCAAGGCGCATTTCCTGCCGTTTTACAGGGATGGCAAGACCGC
TCATGCGGCCGCACCGGAATTGTCAGAGAGCCTGAAGGCACAGATGCCGCTGTCGATGGTGGTTCTGGGCATGGGCAACG
ACATGCATACGGCCTCCCTTTTTCCGGGTGCGAGGGGATTGTCGCAGGCCCTGCACCCCGACGCGCCCGCTCTGTGTCCG
ATCGACGCCGAAAGCCAGCCTGATGTGCGCATCACGCTCAGTGCGGCGGCGTTGAACGGCGCGTTGGAAAAGCACCTGAT
CATCTTCGGGCAGGACAAACGCGACGCATTGGAACGTGCCATGGGACAACCACCGGAACAGGCACCAATCGCTGCAGTCA
TTCAGGGAGGGACCGTCCATTGGGCCGCATGA

Upstream 100 bases:

>100_bases
GGGCGATGTGCCAAAACCCTATGACAGCCTGAGCGACGGGCCGGATGCATCCGCGCAGCTGCTGGTGCGGGACAAGAGAG
AATGGCGAAAGATCTGAACC

Downstream 100 bases:

>100_bases
TGTCAATTTGGGATGCCCTGCGCGAGAAACAGGCGCAGGTAAGCGACCGTTCAATCCTGTCCTTGTTTGACGATCCCGGG
CGCGCGCAGGAGTACAGCGC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MQIIEYIDRDLAAIGVADTLASGLKKALSIQERVSLAVPGGTTPGPIFDVLSAAVLDWDRVTIMLTDERWVPEDHARSNA
ALIRSRLMQGPAAKAHFLPFYRDGKTAHAAAPELSESLKAQMPLSMVVLGMGNDMHTASLFPGARGLSQALHPDAPALCP
IDAESQPDVRITLSAAALNGALEKHLIIFGQDKRDALERAMGQPPEQAPIAAVIQGGTVHWAA

Sequences:

>Translated_223_residues
MQIIEYIDRDLAAIGVADTLASGLKKALSIQERVSLAVPGGTTPGPIFDVLSAAVLDWDRVTIMLTDERWVPEDHARSNA
ALIRSRLMQGPAAKAHFLPFYRDGKTAHAAAPELSESLKAQMPLSMVVLGMGNDMHTASLFPGARGLSQALHPDAPALCP
IDAESQPDVRITLSAAALNGALEKHLIIFGQDKRDALERAMGQPPEQAPIAAVIQGGTVHWAA
>Mature_223_residues
MQIIEYIDRDLAAIGVADTLASGLKKALSIQERVSLAVPGGTTPGPIFDVLSAAVLDWDRVTIMLTDERWVPEDHARSNA
ALIRSRLMQGPAAKAHFLPFYRDGKTAHAAAPELSESLKAQMPLSMVVLGMGNDMHTASLFPGARGLSQALHPDAPALCP
IDAESQPDVRITLSAAALNGALEKHLIIFGQDKRDALERAMGQPPEQAPIAAVIQGGTVHWAA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=206, Percent_Identity=31.0679611650485, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 23722; Mature: 23722

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIIEYIDRDLAAIGVADTLASGLKKALSIQERVSLAVPGGTTPGPIFDVLSAAVLDWDR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCE
VTIMLTDERWVPEDHARSNAALIRSRLMQGPAAKAHFLPFYRDGKTAHAAAPELSESLKA
EEEEEECCCCCCHHHCCCHHHHHHHHHHCCCCCCHHCCCEECCCCCCHHCCHHHHHHHHH
QMPLSMVVLGMGNDMHTASLFPGARGLSQALHPDAPALCPIDAESQPDVRITLSAAALNG
HCCEEEEEEECCCCCCCHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHH
ALEKHLIIFGQDKRDALERAMGQPPEQAPIAAVIQGGTVHWAA
HHHCEEEEEECCHHHHHHHHHCCCCCCCCEEEEEECCEEEECC
>Mature Secondary Structure
MQIIEYIDRDLAAIGVADTLASGLKKALSIQERVSLAVPGGTTPGPIFDVLSAAVLDWDR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCE
VTIMLTDERWVPEDHARSNAALIRSRLMQGPAAKAHFLPFYRDGKTAHAAAPELSESLKA
EEEEEECCCCCCHHHCCCHHHHHHHHHHCCCCCCHHCCCEECCCCCCHHCCHHHHHHHHH
QMPLSMVVLGMGNDMHTASLFPGARGLSQALHPDAPALCPIDAESQPDVRITLSAAALNG
HCCEEEEEEECCCCCCCHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHH
ALEKHLIIFGQDKRDALERAMGQPPEQAPIAAVIQGGTVHWAA
HHHCEEEEEECCHHHHHHHHHCCCCCCCCEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]