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The map label for this gene is pgi

Identifier: 110679935

GI number: 110679935

Start: 2590817

End: 2592409

Strand: Reverse

Name: pgi

Synonym: RD1_2720

Alternate gene names: 110679935

Gene position: 2592409-2590817 (Counterclockwise)

Preceding gene: 110679936

Following gene: 110679931

Centisome position: 62.72

GC content: 60.83

Gene sequence:

>1593_bases
ATGATGTCAATTTGGGATGCCCTGCGCGAGAAACAGGCGCAGGTAAGCGACCGTTCAATCCTGTCCTTGTTTGACGATCC
CGGGCGCGCGCAGGAGTACAGCGCCAAAACGGGCGATCTGTTTTTTGACTTCTCCAAGACCAATATCGACGATGAGGCGC
TGAACCTGCTGTCGGGCTTGCTGGATGCATCCGGCATGGCACAAAAGCGCACCGCGATGTTCTCAGGACAGCCCATCAAT
GACACCGAAGGGCGCGCGGTCTTGCACACGGCGCTGCGCAATCTGGATGGCGGCCCGGTTCTGGTGAATGGCACGGATGT
CATGCCGGGTGTTCTGGCGACGCTTGAGCGGATGCGGGTCTTCGCGCAGGGTGTGCGCGACAGTGACGTTACGGATGTGG
TCAACATCGGGATCGGGGGGTCGGACCTTGGCCCGGCGATGGCGGTTGCCGCCCTGTCGCCTTATCATGACGGGCCACGG
TGTCACTTCGTCTCGAATGTGGATGGGGCGCATATCGCCGATACGCTGCGCGGTCTGGATGCGAAAAAAACGCTGGTGAT
AGTGGCTTCCAAGACCTTCACGACCATTGAAACCATGACGAATGCCCGCACGGCGCGCGCCTGGATGACAGAGCACGGAG
GCGATCCGAAGGCGCAATTTGCAGCGCTTTCCACGGCGGATGACTTGACGGCCGCCTTTGGTATCCCGCCCGAACGTGTC
TTCGGGTTTGAGGATTGGGTCGGCGGGCGATACTCCGTCTGGGGGCCAATTGGCCTGTCCCTGATGATCGCCATCGGACC
ACGCGCCTTTGATGCGTTCTTGCGTGGCGGACAGGCGATGGACCGCCATTTTCAGGCTGCCGACTGGCGCGAAAACCTGC
CGGTCTTGCTGGCTCTGGTCGGCGTGTGGCATGCGCAGGTCTGCGGCTGCAGCAGCCGTGCTGTGCTTCCCTACGATCAG
CGTCTGGCCAAGCTGCCCGATTACCTGCAGCAGCTGGAAATGGAATCGAACGGCAAAAGCGTTCAGATCGGGGGCGCGGA
TGTCACCGTTGACAGCGGCCCCATCGTCTGGGGGGCCGCCGGGACAAATGGCCAACATGCGTTTTATCAACTGATCCATC
AGGGCACGCGGGTTGTCCCATGTGAATTCCTCGTGGCGGCCGAAGGGCATGAGCCCGAGCTTGCCCATCACCACAACCTG
CTGGTTGCGAATTGTCTGGCGCAGTCCGAGGCGCTGATGCGCGGGCGCTCGATTGAGGACGCGCGCGCCAAGATGGTTCA
GGCGGGTTTTACCGGGCAGGAACTTGAACGTCAGGCGCGGCACCGTGTCTTCGCGGGCAACCGCCCCTCCGTGACACTGG
CCTATCCCAAACTTGATCCGTTTATGTTGGGTCAGATCATCGCGCTTTATGAACACCGGGTGTTCGTGGAGGGCGTCATT
CTGGGCATCAACTCCTACGATCAATGGGGCGTCGAATTGGGCAAGGAGCTTGCCACGTCGCTGCAACCCATCGTGGACGG
GGAAGCGCCTGCAGATGGCAAGGATGGATCAACGGCGCAATTGGTCGGCTATGTGATTGCAAACCGGGGTTAA

Upstream 100 bases:

>100_bases
GGCAGGACAAACGCGACGCATTGGAACGTGCCATGGGACAACCACCGGAACAGGCACCAATCGCTGCAGTCATTCAGGGA
GGGACCGTCCATTGGGCCGC

Downstream 100 bases:

>100_bases
TTGTCTTGCTTGGCACCGTCGACATCGACAAATCGCTGTTTCAGTGCGTCGGGAATGGCATATCGGCCACTGCCATCCGG
GTGCAGCAAGACCAGCACGC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MMSIWDALREKQAQVSDRSILSLFDDPGRAQEYSAKTGDLFFDFSKTNIDDEALNLLSGLLDASGMAQKRTAMFSGQPIN
DTEGRAVLHTALRNLDGGPVLVNGTDVMPGVLATLERMRVFAQGVRDSDVTDVVNIGIGGSDLGPAMAVAALSPYHDGPR
CHFVSNVDGAHIADTLRGLDAKKTLVIVASKTFTTIETMTNARTARAWMTEHGGDPKAQFAALSTADDLTAAFGIPPERV
FGFEDWVGGRYSVWGPIGLSLMIAIGPRAFDAFLRGGQAMDRHFQAADWRENLPVLLALVGVWHAQVCGCSSRAVLPYDQ
RLAKLPDYLQQLEMESNGKSVQIGGADVTVDSGPIVWGAAGTNGQHAFYQLIHQGTRVVPCEFLVAAEGHEPELAHHHNL
LVANCLAQSEALMRGRSIEDARAKMVQAGFTGQELERQARHRVFAGNRPSVTLAYPKLDPFMLGQIIALYEHRVFVEGVI
LGINSYDQWGVELGKELATSLQPIVDGEAPADGKDGSTAQLVGYVIANRG

Sequences:

>Translated_530_residues
MMSIWDALREKQAQVSDRSILSLFDDPGRAQEYSAKTGDLFFDFSKTNIDDEALNLLSGLLDASGMAQKRTAMFSGQPIN
DTEGRAVLHTALRNLDGGPVLVNGTDVMPGVLATLERMRVFAQGVRDSDVTDVVNIGIGGSDLGPAMAVAALSPYHDGPR
CHFVSNVDGAHIADTLRGLDAKKTLVIVASKTFTTIETMTNARTARAWMTEHGGDPKAQFAALSTADDLTAAFGIPPERV
FGFEDWVGGRYSVWGPIGLSLMIAIGPRAFDAFLRGGQAMDRHFQAADWRENLPVLLALVGVWHAQVCGCSSRAVLPYDQ
RLAKLPDYLQQLEMESNGKSVQIGGADVTVDSGPIVWGAAGTNGQHAFYQLIHQGTRVVPCEFLVAAEGHEPELAHHHNL
LVANCLAQSEALMRGRSIEDARAKMVQAGFTGQELERQARHRVFAGNRPSVTLAYPKLDPFMLGQIIALYEHRVFVEGVI
LGINSYDQWGVELGKELATSLQPIVDGEAPADGKDGSTAQLVGYVIANRG
>Mature_530_residues
MMSIWDALREKQAQVSDRSILSLFDDPGRAQEYSAKTGDLFFDFSKTNIDDEALNLLSGLLDASGMAQKRTAMFSGQPIN
DTEGRAVLHTALRNLDGGPVLVNGTDVMPGVLATLERMRVFAQGVRDSDVTDVVNIGIGGSDLGPAMAVAALSPYHDGPR
CHFVSNVDGAHIADTLRGLDAKKTLVIVASKTFTTIETMTNARTARAWMTEHGGDPKAQFAALSTADDLTAAFGIPPERV
FGFEDWVGGRYSVWGPIGLSLMIAIGPRAFDAFLRGGQAMDRHFQAADWRENLPVLLALVGVWHAQVCGCSSRAVLPYDQ
RLAKLPDYLQQLEMESNGKSVQIGGADVTVDSGPIVWGAAGTNGQHAFYQLIHQGTRVVPCEFLVAAEGHEPELAHHHNL
LVANCLAQSEALMRGRSIEDARAKMVQAGFTGQELERQARHRVFAGNRPSVTLAYPKLDPFMLGQIIALYEHRVFVEGVI
LGINSYDQWGVELGKELATSLQPIVDGEAPADGKDGSTAQLVGYVIANRG

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Homo sapiens, GI18201905, Length=532, Percent_Identity=48.1203007518797, Blast_Score=520, Evalue=1e-147,
Organism=Homo sapiens, GI296080693, Length=524, Percent_Identity=45.9923664122137, Blast_Score=484, Evalue=1e-136,
Organism=Escherichia coli, GI1790457, Length=539, Percent_Identity=46.9387755102041, Blast_Score=483, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI71996708, Length=537, Percent_Identity=45.8100558659218, Blast_Score=484, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI71996703, Length=537, Percent_Identity=45.8100558659218, Blast_Score=484, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6319673, Length=539, Percent_Identity=43.4137291280148, Blast_Score=442, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24651916, Length=531, Percent_Identity=48.5875706214689, Blast_Score=516, Evalue=1e-146,
Organism=Drosophila melanogaster, GI24651914, Length=531, Percent_Identity=48.5875706214689, Blast_Score=516, Evalue=1e-146,
Organism=Drosophila melanogaster, GI17737445, Length=531, Percent_Identity=48.5875706214689, Blast_Score=516, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_ROSDO (Q165T7)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682942.1
- ProteinModelPortal:   Q165T7
- SMR:   Q165T7
- STRING:   Q165T7
- GeneID:   4196185
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2720
- NMPDR:   fig|375451.6.peg.2521
- eggNOG:   COG0166
- HOGENOM:   HBG352954
- OMA:   INAQHAF
- PhylomeDB:   Q165T7
- ProtClustDB:   PRK00179
- BioCyc:   RDEN375451:RD1_2720-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189
- Gene3D:   G3DSA:1.10.1390.10
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 57177; Mature: 57177

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 335-335 ACT_SITE 366-366 ACT_SITE 495-495

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSIWDALREKQAQVSDRSILSLFDDPGRAQEYSAKTGDLFFDFSKTNIDDEALNLLSGL
CCCHHHHHHHHHHHHCHHHHHHHHCCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
LDASGMAQKRTAMFSGQPINDTEGRAVLHTALRNLDGGPVLVNGTDVMPGVLATLERMRV
HCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
FAQGVRDSDVTDVVNIGIGGSDLGPAMAVAALSPYHDGPRCHFVSNVDGAHIADTLRGLD
HHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHCCC
AKKTLVIVASKTFTTIETMTNARTARAWMTEHGGDPKAQFAALSTADDLTAAFGIPPERV
CCCEEEEEECCCHHHHHHHHCCHHHHHHHHHCCCCCHHHEEEECCCHHHHHHCCCCHHHH
FGFEDWVGGRYSVWGPIGLSLMIAIGPRAFDAFLRGGQAMDRHFQAADWRENLPVLLALV
CCCHHHCCCCEEEECCCCEEEEEEECHHHHHHHHCCCHHHHHHCCCCCHHCCCHHHHHHH
GVWHAQVCGCSSRAVLPYDQRLAKLPDYLQQLEMESNGKSVQIGGADVTVDSGPIVWGAA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCEEEECC
GTNGQHAFYQLIHQGTRVVPCEFLVAAEGHEPELAHHHNLLVANCLAQSEALMRGRSIED
CCCCHHHHHHHHHCCCEEECEEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCHH
ARAKMVQAGFTGQELERQARHRVFAGNRPSVTLAYPKLDPFMLGQIIALYEHRVFVEGVI
HHHHHHHCCCCHHHHHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHHHHHEEEEEEE
LGINSYDQWGVELGKELATSLQPIVDGEAPADGKDGSTAQLVGYVIANRG
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEECCC
>Mature Secondary Structure
MMSIWDALREKQAQVSDRSILSLFDDPGRAQEYSAKTGDLFFDFSKTNIDDEALNLLSGL
CCCHHHHHHHHHHHHCHHHHHHHHCCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
LDASGMAQKRTAMFSGQPINDTEGRAVLHTALRNLDGGPVLVNGTDVMPGVLATLERMRV
HCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
FAQGVRDSDVTDVVNIGIGGSDLGPAMAVAALSPYHDGPRCHFVSNVDGAHIADTLRGLD
HHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHCCC
AKKTLVIVASKTFTTIETMTNARTARAWMTEHGGDPKAQFAALSTADDLTAAFGIPPERV
CCCEEEEEECCCHHHHHHHHCCHHHHHHHHHCCCCCHHHEEEECCCHHHHHHCCCCHHHH
FGFEDWVGGRYSVWGPIGLSLMIAIGPRAFDAFLRGGQAMDRHFQAADWRENLPVLLALV
CCCHHHCCCCEEEECCCCEEEEEEECHHHHHHHHCCCHHHHHHCCCCCHHCCCHHHHHHH
GVWHAQVCGCSSRAVLPYDQRLAKLPDYLQQLEMESNGKSVQIGGADVTVDSGPIVWGAA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCEEEECC
GTNGQHAFYQLIHQGTRVVPCEFLVAAEGHEPELAHHHNLLVANCLAQSEALMRGRSIED
CCCCHHHHHHHHHCCCEEECEEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCHH
ARAKMVQAGFTGQELERQARHRVFAGNRPSVTLAYPKLDPFMLGQIIALYEHRVFVEGVI
HHHHHHHCCCCHHHHHHHHHHHEECCCCCCEEEECCCCCHHHHHHHHHHHHHHEEEEEEE
LGINSYDQWGVELGKELATSLQPIVDGEAPADGKDGSTAQLVGYVIANRG
EECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA