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The map label for this gene is glsA [H]

Identifier: 110679906

GI number: 110679906

Start: 2558058

End: 2558963

Strand: Direct

Name: glsA [H]

Synonym: RD1_2684

Alternate gene names: 110679906

Gene position: 2558058-2558963 (Clockwise)

Preceding gene: 110679905

Following gene: 110679907

Centisome position: 61.89

GC content: 57.4

Gene sequence:

>906_bases
GTGTTGGAAAAAATCATTGAATCCATCGCCGCAGAGATACGCCAGCAAGACGACTGGGGTGAAACCGCGCAATACATCCC
GGAACTTGCGACAGTTGATCCAAAGCAATTCGCCATCAGCGTATGTTTGGCGGACGGCCGGATGATCAGTGCCGGATCGG
CGACAAAACCATTTTCCATTCAGAGCATCTCCAAGGTCTTTGCACTTGTCGCTGCACTTGGGCGGGTCGGGAACCAGCTT
TGGAGCCGCACCGGACGCGAACCGTCAGGCACGTCCTTTGATTCCATGGTCCTGCTGGAGCGGGAGAATGGCCGCCCCCG
CAACCCTTTTATCAATGCCGGTGCAATCGTCACGACAGATGCCCTGCTGTGCGGACGTCCGCCCAAACAGGCGCTGGCCG
AAATTCTTGGGCTTGTCAGACAGATGTCCGGGTCCAACGGCATCTTCATCAACGACGCTGTTGCGGCTTCCGAGCAAAGA
ACGGGGTCGCGCAACAAAGCGCTTGCCTATTACCTTCAGTCCCATGGAAACCTTGTGAATGACCCGGACCTGACGCTTGG
CACATATTTTCACCAATGCGCAATCGAGATGACGACAGAGCAACTGGCGATGGCCGGTCGGTCGCTGGCTGGCCTTGAGG
GCGCACCAAGGGTCATATCGTTGAAACACGTTCGACGGGTCAATGCGCTTATGATGACCTGCGGGCACTATAACGGCTCG
GGCGATTTTGCCTTCCGCGTCGGACTGCCGGGCAAAAGCGGCGTCGGCGGGGGCATCCTGATCATCGCGCCCAAAGTCGC
ATCCATTGCAATCTGGTCGCCGGGTCTGAACCACTATGGCAATTCCTATGCCGGCACACGCGCGGCGGAAATGCTCTCCA
AGGCAACCAATTGGTCGGTGTTTTGA

Upstream 100 bases:

>100_bases
TTCAGGTATTTGGTCGGACGCTTTAAAATGGAACTGAAGCCAGCGGGCTTGATCTGCTATATCCAAAAGCACGCCGCAGG
ATTTTCCGCGTTGGGAGGCA

Downstream 100 bases:

>100_bases
ACGCTCGGCATCGGGCGCTCTTATGCGCCATGCTGAGGTCGCGCGGCACAAATCTGCCCTGCTGACACAGGCCGAGGCAG
GATCACGTTAACAACCTAAA

Product: glutaminase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLEKIIESIAAEIRQQDDWGETAQYIPELATVDPKQFAISVCLADGRMISAGSATKPFSIQSISKVFALVAALGRVGNQL
WSRTGREPSGTSFDSMVLLERENGRPRNPFINAGAIVTTDALLCGRPPKQALAEILGLVRQMSGSNGIFINDAVAASEQR
TGSRNKALAYYLQSHGNLVNDPDLTLGTYFHQCAIEMTTEQLAMAGRSLAGLEGAPRVISLKHVRRVNALMMTCGHYNGS
GDFAFRVGLPGKSGVGGGILIIAPKVASIAIWSPGLNHYGNSYAGTRAAEMLSKATNWSVF

Sequences:

>Translated_301_residues
MLEKIIESIAAEIRQQDDWGETAQYIPELATVDPKQFAISVCLADGRMISAGSATKPFSIQSISKVFALVAALGRVGNQL
WSRTGREPSGTSFDSMVLLERENGRPRNPFINAGAIVTTDALLCGRPPKQALAEILGLVRQMSGSNGIFINDAVAASEQR
TGSRNKALAYYLQSHGNLVNDPDLTLGTYFHQCAIEMTTEQLAMAGRSLAGLEGAPRVISLKHVRRVNALMMTCGHYNGS
GDFAFRVGLPGKSGVGGGILIIAPKVASIAIWSPGLNHYGNSYAGTRAAEMLSKATNWSVF
>Mature_301_residues
MLEKIIESIAAEIRQQDDWGETAQYIPELATVDPKQFAISVCLADGRMISAGSATKPFSIQSISKVFALVAALGRVGNQL
WSRTGREPSGTSFDSMVLLERENGRPRNPFINAGAIVTTDALLCGRPPKQALAEILGLVRQMSGSNGIFINDAVAASEQR
TGSRNKALAYYLQSHGNLVNDPDLTLGTYFHQCAIEMTTEQLAMAGRSLAGLEGAPRVISLKHVRRVNALMMTCGHYNGS
GDFAFRVGLPGKSGVGGGILIIAPKVASIAIWSPGLNHYGNSYAGTRAAEMLSKATNWSVF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=289, Percent_Identity=36.3321799307958, Blast_Score=187, Evalue=9e-48,
Organism=Homo sapiens, GI20336214, Length=289, Percent_Identity=33.9100346020761, Blast_Score=168, Evalue=6e-42,
Organism=Escherichia coli, GI1787804, Length=308, Percent_Identity=44.4805194805195, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1786693, Length=287, Percent_Identity=39.7212543554007, Blast_Score=182, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17507019, Length=301, Percent_Identity=37.5415282392027, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17532727, Length=299, Percent_Identity=35.7859531772575, Blast_Score=173, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI193204073, Length=314, Percent_Identity=33.1210191082803, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI193204075, Length=316, Percent_Identity=32.9113924050633, Blast_Score=170, Evalue=8e-43,
Organism=Drosophila melanogaster, GI281363241, Length=309, Percent_Identity=35.5987055016181, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653162, Length=309, Percent_Identity=35.5987055016181, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281363239, Length=309, Percent_Identity=35.5987055016181, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653166, Length=309, Percent_Identity=35.5987055016181, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653156, Length=309, Percent_Identity=35.5987055016181, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653164, Length=309, Percent_Identity=35.5987055016181, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653158, Length=309, Percent_Identity=35.5987055016181, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI116008307, Length=309, Percent_Identity=35.5987055016181, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32172; Mature: 32172

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKIIESIAAEIRQQDDWGETAQYIPELATVDPKQFAISVCLADGRMISAGSATKPFSI
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHEEEEEEECCEEEECCCCCCCCHH
QSISKVFALVAALGRVGNQLWSRTGREPSGTSFDSMVLLERENGRPRNPFINAGAIVTTD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEHH
ALLCGRPPKQALAEILGLVRQMSGSNGIFINDAVAASEQRTGSRNKALAYYLQSHGNLVN
HHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHCCCCCC
DPDLTLGTYFHQCAIEMTTEQLAMAGRSLAGLEGAPRVISLKHVRRVNALMMTCGHYNGS
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCC
GDFAFRVGLPGKSGVGGGILIIAPKVASIAIWSPGLNHYGNSYAGTRAAEMLSKATNWSV
CCEEEEEECCCCCCCCCCEEEEECCCCEEEEECCCHHHCCCCCCHHHHHHHHHHCCCCCC
F
C
>Mature Secondary Structure
MLEKIIESIAAEIRQQDDWGETAQYIPELATVDPKQFAISVCLADGRMISAGSATKPFSI
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHEEEEEEECCEEEECCCCCCCCHH
QSISKVFALVAALGRVGNQLWSRTGREPSGTSFDSMVLLERENGRPRNPFINAGAIVTTD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEHH
ALLCGRPPKQALAEILGLVRQMSGSNGIFINDAVAASEQRTGSRNKALAYYLQSHGNLVN
HHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHHCCCCCC
DPDLTLGTYFHQCAIEMTTEQLAMAGRSLAGLEGAPRVISLKHVRRVNALMMTCGHYNGS
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCC
GDFAFRVGLPGKSGVGGGILIIAPKVASIAIWSPGLNHYGNSYAGTRAAEMLSKATNWSV
CCEEEEEECCCCCCCCCCEEEEECCCCEEEEECCCHHHCCCCCCHHHHHHHHHHCCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA