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The map label for this gene is obgE

Identifier: 110679886

GI number: 110679886

Start: 2538871

End: 2539905

Strand: Reverse

Name: obgE

Synonym: RD1_2660

Alternate gene names: 110679886

Gene position: 2539905-2538871 (Counterclockwise)

Preceding gene: 110679887

Following gene: 110679885

Centisome position: 61.45

GC content: 57.0

Gene sequence:

>1035_bases
ATGAAATTTCTTGATCTATGCAAAGTCTACATTCGATCCGGCGCGGGCGGGGGCGGTTGTGTCAGCTTCCGGCGCGAAAA
ATATATCGAATACGGTGGTCCTGACGGCGGCGATGGGGGCACTGGCGGCTCGGTCTGGGCCGAAGCTGTTGACGGGCTCA
ACACCTTGATTGATTTTCGCTATCAACAGCATTTCTTTGCCAAGAACGGGCAGCCGGGCATGGGCCGGCAGCGCACGGGC
AAAGACGGCGACGACATTGTATTGCGCGTTCCCGTGGGCACCGAAATCCTCGACGAGGATCAGGAAACCGTCATATGCGA
CCTGACCGAGGTTGGCCAACGGGTGCAACTGGCACGTGGGGGCAACGGGGGTTTTGGCAATCTGCATTTCAAATCCTCGA
CCAATCAGGCCCCGAGGCGCAGTAATCCCGGTCAGGACGGTGTCGAAAGAACGCTGTGGCTGCGCCTGAAATTGATCGCG
GATGTGGGCCTGCTCGGTCTGCCCAATGCGGGGAAATCGACCTTTCTGGCGGCGACCTCGAATGCGCGCCCCAAGATTGC
GGATTATCCCTTTACAACGCTACATCCGAACCTTGGCGTTGTGGGTGTCGACAACACGGAATTTGTCGTGGCGGATATCC
CCGGCCTGATTGAGGGCGCATCAGAAGGGCGTGGCCTTGGAGATCTCTTCCTTGGTCATATCGAGCGGTGTGCCGTGTTG
CTGCATCTCTTTGACGGCACCTCCGAAACCCTTATTGAGGACTACCATACCATAATTGGTGAACTCGAAGCCTATGGCGT
TGGTCTGGCGGACAAACCGCGCATTACCGTTCTCAACAAGATTGATGCACTGGATGAAGAGCGCCGTGCAATGGCATTGA
AACAGTTGAATAATGTATGTGGCGGGGGTGTGATGGCGATGTCCGGTGTTGCCGGGGACGGCGTCACTGATGTGTTGCGA
AAACTGCGCGGCGAGATCAGCGATGAGCCGCTGCGCCATAAACCTGTCGAGGAAAAAGAACCATGGCGGCCCTGA

Upstream 100 bases:

>100_bases
CAGAAAGTTTCAGTGTCGCGCGCGGGACAACAGTGCCAACCTGGACGTATCTGAAAAAACTGTAATTGAGGGGCGCCGCC
CTTCAGGCTAGGAAGCTTGC

Downstream 100 bases:

>100_bases
CGGACGCAGATTGTCTGGTCGTCAAGATCGGGTCCGCCCTGTTGGTGGACCGGGACGCGGGCGGCTTGCGGCAGGCGTGG
CTTGCGTCGCTGGCGCAGGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKFLDLCKVYIRSGAGGGGCVSFRREKYIEYGGPDGGDGGTGGSVWAEAVDGLNTLIDFRYQQHFFAKNGQPGMGRQRTG
KDGDDIVLRVPVGTEILDEDQETVICDLTEVGQRVQLARGGNGGFGNLHFKSSTNQAPRRSNPGQDGVERTLWLRLKLIA
DVGLLGLPNAGKSTFLAATSNARPKIADYPFTTLHPNLGVVGVDNTEFVVADIPGLIEGASEGRGLGDLFLGHIERCAVL
LHLFDGTSETLIEDYHTIIGELEAYGVGLADKPRITVLNKIDALDEERRAMALKQLNNVCGGGVMAMSGVAGDGVTDVLR
KLRGEISDEPLRHKPVEEKEPWRP

Sequences:

>Translated_344_residues
MKFLDLCKVYIRSGAGGGGCVSFRREKYIEYGGPDGGDGGTGGSVWAEAVDGLNTLIDFRYQQHFFAKNGQPGMGRQRTG
KDGDDIVLRVPVGTEILDEDQETVICDLTEVGQRVQLARGGNGGFGNLHFKSSTNQAPRRSNPGQDGVERTLWLRLKLIA
DVGLLGLPNAGKSTFLAATSNARPKIADYPFTTLHPNLGVVGVDNTEFVVADIPGLIEGASEGRGLGDLFLGHIERCAVL
LHLFDGTSETLIEDYHTIIGELEAYGVGLADKPRITVLNKIDALDEERRAMALKQLNNVCGGGVMAMSGVAGDGVTDVLR
KLRGEISDEPLRHKPVEEKEPWRP
>Mature_344_residues
MKFLDLCKVYIRSGAGGGGCVSFRREKYIEYGGPDGGDGGTGGSVWAEAVDGLNTLIDFRYQQHFFAKNGQPGMGRQRTG
KDGDDIVLRVPVGTEILDEDQETVICDLTEVGQRVQLARGGNGGFGNLHFKSSTNQAPRRSNPGQDGVERTLWLRLKLIA
DVGLLGLPNAGKSTFLAATSNARPKIADYPFTTLHPNLGVVGVDNTEFVVADIPGLIEGASEGRGLGDLFLGHIERCAVL
LHLFDGTSETLIEDYHTIIGELEAYGVGLADKPRITVLNKIDALDEERRAMALKQLNNVCGGGVMAMSGVAGDGVTDVLR
KLRGEISDEPLRHKPVEEKEPWRP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=325, Percent_Identity=40.9230769230769, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI111955139, Length=357, Percent_Identity=33.8935574229692, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI111955063, Length=204, Percent_Identity=35.7843137254902, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI58761500, Length=99, Percent_Identity=37.3737373737374, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=34.7107438016529, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=33.0508474576271, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789574, Length=349, Percent_Identity=51.2893982808023, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI1787454, Length=101, Percent_Identity=37.6237623762376, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=281, Percent_Identity=41.2811387900356, Blast_Score=148, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=310, Percent_Identity=31.6129032258064, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=171, Percent_Identity=35.0877192982456, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=33.8983050847458, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555344, Length=114, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=172, Percent_Identity=42.4418604651163, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=115, Percent_Identity=33.0434782608696, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321612, Length=117, Percent_Identity=34.1880341880342, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129375, Length=326, Percent_Identity=36.8098159509202, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=37.6712328767123, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24640873, Length=145, Percent_Identity=31.7241379310345, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640877, Length=145, Percent_Identity=31.7241379310345, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640875, Length=145, Percent_Identity=31.7241379310345, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_ROSDO (Q165Y6)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682893.1
- ProteinModelPortal:   Q165Y6
- SMR:   Q165Y6
- STRING:   Q165Y6
- GeneID:   4196208
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2660
- NMPDR:   fig|375451.6.peg.2473
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- PhylomeDB:   Q165Y6
- ProtClustDB:   PRK12299
- BioCyc:   RDEN375451:RD1_2660-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 37056; Mature: 37056

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDLCKVYIRSGAGGGGCVSFRREKYIEYGGPDGGDGGTGGSVWAEAVDGLNTLIDFR
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YQQHFFAKNGQPGMGRQRTGKDGDDIVLRVPVGTEILDEDQETVICDLTEVGQRVQLARG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCEEEEEHHHHCCEEEEEEC
GNGGFGNLHFKSSTNQAPRRSNPGQDGVERTLWLRLKLIADVGLLGLPNAGKSTFLAATS
CCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECC
NARPKIADYPFTTLHPNLGVVGVDNTEFVVADIPGLIEGASEGRGLGDLFLGHIERCAVL
CCCCCCCCCCCEEECCCCCEEECCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHH
LHLFDGTSETLIEDYHTIIGELEAYGVGLADKPRITVLNKIDALDEERRAMALKQLNNVC
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHC
GGGVMAMSGVAGDGVTDVLRKLRGEISDEPLRHKPVEEKEPWRP
CCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFLDLCKVYIRSGAGGGGCVSFRREKYIEYGGPDGGDGGTGGSVWAEAVDGLNTLIDFR
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YQQHFFAKNGQPGMGRQRTGKDGDDIVLRVPVGTEILDEDQETVICDLTEVGQRVQLARG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCEEEEEHHHHCCEEEEEEC
GNGGFGNLHFKSSTNQAPRRSNPGQDGVERTLWLRLKLIADVGLLGLPNAGKSTFLAATS
CCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECC
NARPKIADYPFTTLHPNLGVVGVDNTEFVVADIPGLIEGASEGRGLGDLFLGHIERCAVL
CCCCCCCCCCCEEECCCCCEEECCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHH
LHLFDGTSETLIEDYHTIIGELEAYGVGLADKPRITVLNKIDALDEERRAMALKQLNNVC
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHC
GGGVMAMSGVAGDGVTDVLRKLRGEISDEPLRHKPVEEKEPWRP
CCCCEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA