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The map label for this gene is ccmC [H]

Identifier: 110679785

GI number: 110679785

Start: 2437604

End: 2438371

Strand: Direct

Name: ccmC [H]

Synonym: RD1_2549

Alternate gene names: 110679785

Gene position: 2437604-2438371 (Clockwise)

Preceding gene: 110679784

Following gene: 110679786

Centisome position: 58.98

GC content: 58.85

Gene sequence:

>768_bases
ATGACACTGACCAACGAAAAACCCGCGCCCAAACGGCCCAGTTCGTTCTGGAGCTATGCCAATCCGGTCAAGTTCCTTGC
ACTGAGCGAACGTGTCCTGCCGACGCTTTGGGTGCTTGCGGCCACCAGTCTTGTTGTTGGTCTGGTCTGGGGCTTTTTCT
TTACGCCGGATGATTTCCGGCAGGGCTCGACGGTCAAGATCATCTATCTGCATGTGCCCTCTGCAATGATGGCGATCAAT
ATCTGGGTCATGATGCTTGTCACCTCTCTGATCTGGATCATCCGACGCCATCACGTCAGTGCGCTTGCAGCAAAGGCCGC
GGCACCGATTGGCGTGGTGATGACTATTATTGCCCTTGTTACGGGCGCGCTCTGGGGCCAGCCCATGTGGGGCACGTGGT
GGGCGTGGGATCCGCGCCTGACGTCGTTCCTCATCCTGTTTTTGTTTTACCTTGGCTACATCGCGCTTTGGGCTGCCATT
GAGGACCCGGATACGGCGGCTGATCTGACGGCTGTGCTCTGCCTGGTCGGGTCCGTCTTTGCGGTCCTGTCGCGCTATGC
AGTGAATTTCTGGAACCAAGGCCTGCATCAGGGCGCATCGCTGAGCCTCGACAAGGAAGAGAACGTGGCGGATGTATTCT
ACTTTCCGCTGCTGGTGGCCATCGCGGGGTTTGTGCTGCTGTTTCTGGCGCTGGTGCTCTACCGCACGGGTACGGAAATC
AGGCTGCGCCGCGCCAAGGCCCTGTTGGCACGGGAGGCCCGCTCATGA

Upstream 100 bases:

>100_bases
GTCATGCCCTTTGCATCCGCTGCTGCCCTGCGCGTAAATCTGCGATAAGCGTGGCGTTTTGCCCATTGAGGCTCGTGGGG
CGAGTGACTAAATACGGAGC

Downstream 100 bases:

>100_bases
TGCCCGATCTTGGAAAGTACAGCGAGGCGGTTTTGTCCTCCTATGCGGCAACGCTATTGTTATTGGCCTTGTTGGTTTTC
ATCACGTTACATAAAGGGCG

Product: heme exporter protein

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein HelC [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTLTNEKPAPKRPSSFWSYANPVKFLALSERVLPTLWVLAATSLVVGLVWGFFFTPDDFRQGSTVKIIYLHVPSAMMAIN
IWVMMLVTSLIWIIRRHHVSALAAKAAAPIGVVMTIIALVTGALWGQPMWGTWWAWDPRLTSFLILFLFYLGYIALWAAI
EDPDTAADLTAVLCLVGSVFAVLSRYAVNFWNQGLHQGASLSLDKEENVADVFYFPLLVAIAGFVLLFLALVLYRTGTEI
RLRRAKALLAREARS

Sequences:

>Translated_255_residues
MTLTNEKPAPKRPSSFWSYANPVKFLALSERVLPTLWVLAATSLVVGLVWGFFFTPDDFRQGSTVKIIYLHVPSAMMAIN
IWVMMLVTSLIWIIRRHHVSALAAKAAAPIGVVMTIIALVTGALWGQPMWGTWWAWDPRLTSFLILFLFYLGYIALWAAI
EDPDTAADLTAVLCLVGSVFAVLSRYAVNFWNQGLHQGASLSLDKEENVADVFYFPLLVAIAGFVLLFLALVLYRTGTEI
RLRRAKALLAREARS
>Mature_254_residues
TLTNEKPAPKRPSSFWSYANPVKFLALSERVLPTLWVLAATSLVVGLVWGFFFTPDDFRQGSTVKIIYLHVPSAMMAINI
WVMMLVTSLIWIIRRHHVSALAAKAAAPIGVVMTIIALVTGALWGQPMWGTWWAWDPRLTSFLILFLFYLGYIALWAAIE
DPDTAADLTAVLCLVGSVFAVLSRYAVNFWNQGLHQGASLSLDKEENVADVFYFPLLVAIAGFVLLFLALVLYRTGTEIR
LRRAKALLAREARS

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=227, Percent_Identity=40.9691629955947, Blast_Score=163, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 28461; Mature: 28330

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLTNEKPAPKRPSSFWSYANPVKFLALSERVLPTLWVLAATSLVVGLVWGFFFTPDDFR
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
QGSTVKIIYLHVPSAMMAINIWVMMLVTSLIWIIRRHHVSALAAKAAAPIGVVMTIIALV
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
TGALWGQPMWGTWWAWDPRLTSFLILFLFYLGYIALWAAIEDPDTAADLTAVLCLVGSVF
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AVLSRYAVNFWNQGLHQGASLSLDKEENVADVFYFPLLVAIAGFVLLFLALVLYRTGTEI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
RLRRAKALLAREARS
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1310666 [H]