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The map label for this gene is trgB [H]

Identifier: 110679558

GI number: 110679558

Start: 2193092

End: 2194195

Strand: Direct

Name: trgB [H]

Synonym: RD1_2298

Alternate gene names: 110679558

Gene position: 2193092-2194195 (Clockwise)

Preceding gene: 110679557

Following gene: 110679559

Centisome position: 53.06

GC content: 62.14

Gene sequence:

>1104_bases
ATGAGACCACTTTTCCTGTTCGGAACACTGCAATATCGACCGCTGCTGGATGCAGTATTGGGGCGCAACAATGATGTGGC
GATGGCTGCTGCAGTGCTGCCGGGGTTTGCAGTGCAGGCCGTGGCTGAGGGCCCTTTCCCGACGATCACGGCGCAAGATG
GTGCGCGGGCCGAGGGGATGGTGATCAGCGGTCTGACCTCAGAAGATCACGCGCGGCTTGCGTTTTATGAAGCGATATTC
GGCTATGGGCTTGCGCCCGTCACCCTTGAAGACGGCGTTCTGGCCGAGGCATATTTCCCCCAGCCGGATATGTGGACTCT
CCAAGGTGCGTGGTCGCTCGATGCCTGGGTCAGTGCGTGGGGCGAACTCAGCCTGCGTGCCGCCCGCGAAGTGATGCAGT
ACCGGCACTCGAAGCGGCCTGATGAGGTTGCTGGCATGTTCCCGATGATCCGCGCGCGGGCGTGGTCACAGATGAATGCC
AAGCAGTCTCGGCACGGTGCCTTGACGCTGATGGGGGATGTGGCGGTTGACGCGGTGCGGCGGCCTTATGCGCATTACTT
TGCGCTTGAGGAATATGACCTCAGGCACCAACGCTTTGACGGAACCATGACGCCGCAGGTGGAACGCGCGGTGTTTCGTG
CGCCCGATGCCGCATTGGTGCTGCCTTATGATCCCGTCCGGGATTGCGTGATGCTGGTGGAACAGATGCGCATGGGCCCC
CTTGCGCGGGGGGATCGGGCGCTGTGGCAACTTGAACCCATTGCGGGCCGTCTGGACCCCGGTGAGGCCCCCGAGGCGGC
GGCAAGGCGCGAAGCGGTGGAAGAGGCCGGTCTTGAGATGGGCGACTTGATTGCCGTGGCGGAAACCTATTGCTCGCCGG
GCAATTCATCGGAGTTTTACTATGTATACGTGGGGCTTGCCGATCTGCCGGAGCGTGCGGCCGGTCTGGGTGGGGAAGAG
GCGGAGGATGAAGACATCCGCTCGCATATCCTGCCGTTTGAGCAGTTGATGACGATGTGTGATGACCTGTTGGTGGCAAA
TGCGCCTTTGGTCATGGCCGCCTATTGGCTGGCCCGCCACCGCGAACGGATACGGGCGGCGTGA

Upstream 100 bases:

>100_bases
AACCCGCTGGTGATGTTCTCCCTGATGGCGGGCGGGGTTCTGGCGGGGCTTGCAACGGAATACGCTTGGCGCATGTGGCG
ATAGCCGTTAACAGTCGGGC

Downstream 100 bases:

>100_bases
GTCAGCGGCTTTTTGTTCAGCCCGCGTGGCACTGGCATACCGCTAAGCCTTGAGGTCGGACGGGTGCCCCGATAGAGGTA
GGTGAAATTCGGCTAAAAAG

Product: tellurite resistance protein TrgB

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MRPLFLFGTLQYRPLLDAVLGRNNDVAMAAAVLPGFAVQAVAEGPFPTITAQDGARAEGMVISGLTSEDHARLAFYEAIF
GYGLAPVTLEDGVLAEAYFPQPDMWTLQGAWSLDAWVSAWGELSLRAAREVMQYRHSKRPDEVAGMFPMIRARAWSQMNA
KQSRHGALTLMGDVAVDAVRRPYAHYFALEEYDLRHQRFDGTMTPQVERAVFRAPDAALVLPYDPVRDCVMLVEQMRMGP
LARGDRALWQLEPIAGRLDPGEAPEAAARREAVEEAGLEMGDLIAVAETYCSPGNSSEFYYVYVGLADLPERAAGLGGEE
AEDEDIRSHILPFEQLMTMCDDLLVANAPLVMAAYWLARHRERIRAA

Sequences:

>Translated_367_residues
MRPLFLFGTLQYRPLLDAVLGRNNDVAMAAAVLPGFAVQAVAEGPFPTITAQDGARAEGMVISGLTSEDHARLAFYEAIF
GYGLAPVTLEDGVLAEAYFPQPDMWTLQGAWSLDAWVSAWGELSLRAAREVMQYRHSKRPDEVAGMFPMIRARAWSQMNA
KQSRHGALTLMGDVAVDAVRRPYAHYFALEEYDLRHQRFDGTMTPQVERAVFRAPDAALVLPYDPVRDCVMLVEQMRMGP
LARGDRALWQLEPIAGRLDPGEAPEAAARREAVEEAGLEMGDLIAVAETYCSPGNSSEFYYVYVGLADLPERAAGLGGEE
AEDEDIRSHILPFEQLMTMCDDLLVANAPLVMAAYWLARHRERIRAA
>Mature_367_residues
MRPLFLFGTLQYRPLLDAVLGRNNDVAMAAAVLPGFAVQAVAEGPFPTITAQDGARAEGMVISGLTSEDHARLAFYEAIF
GYGLAPVTLEDGVLAEAYFPQPDMWTLQGAWSLDAWVSAWGELSLRAAREVMQYRHSKRPDEVAGMFPMIRARAWSQMNA
KQSRHGALTLMGDVAVDAVRRPYAHYFALEEYDLRHQRFDGTMTPQVERAVFRAPDAALVLPYDPVRDCVMLVEQMRMGP
LARGDRALWQLEPIAGRLDPGEAPEAAARREAVEEAGLEMGDLIAVAETYCSPGNSSEFYYVYVGLADLPERAAGLGGEE
AEDEDIRSHILPFEQLMTMCDDLLVANAPLVMAAYWLARHRERIRAA

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789412, Length=194, Percent_Identity=38.1443298969072, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1788810, Length=175, Percent_Identity=32.5714285714286, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 40624; Mature: 40624

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLFLFGTLQYRPLLDAVLGRNNDVAMAAAVLPGFAVQAVAEGPFPTITAQDGARAEGM
CCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHCCCCCEEECCCCCCCCCE
VISGLTSEDHARLAFYEAIFGYGLAPVTLEDGVLAEAYFPQPDMWTLQGAWSLDAWVSAW
EEECCCCCCHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCEEECCCCCHHHHHHHH
GELSLRAAREVMQYRHSKRPDEVAGMFPMIRARAWSQMNAKQSRHGALTLMGDVAVDAVR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
RPYAHYFALEEYDLRHQRFDGTMTPQVERAVFRAPDAALVLPYDPVRDCVMLVEQMRMGP
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCC
LARGDRALWQLEPIAGRLDPGEAPEAAARREAVEEAGLEMGDLIAVAETYCSPGNSSEFY
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEE
YVYVGLADLPERAAGLGGEEAEDEDIRSHILPFEQLMTMCDDLLVANAPLVMAAYWLARH
EEEEECCCCCHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RERIRAA
HHHHCCC
>Mature Secondary Structure
MRPLFLFGTLQYRPLLDAVLGRNNDVAMAAAVLPGFAVQAVAEGPFPTITAQDGARAEGM
CCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHCCCCCEEECCCCCCCCCE
VISGLTSEDHARLAFYEAIFGYGLAPVTLEDGVLAEAYFPQPDMWTLQGAWSLDAWVSAW
EEECCCCCCHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCEEECCCCCHHHHHHHH
GELSLRAAREVMQYRHSKRPDEVAGMFPMIRARAWSQMNAKQSRHGALTLMGDVAVDAVR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
RPYAHYFALEEYDLRHQRFDGTMTPQVERAVFRAPDAALVLPYDPVRDCVMLVEQMRMGP
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCC
LARGDRALWQLEPIAGRLDPGEAPEAAARREAVEEAGLEMGDLIAVAETYCSPGNSSEFY
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEE
YVYVGLADLPERAAGLGGEEAEDEDIRSHILPFEQLMTMCDDLLVANAPLVMAAYWLARH
EEEEECCCCCHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RERIRAA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]