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The map label for this gene is braD [H]

Identifier: 110679439

GI number: 110679439

Start: 2063311

End: 2065320

Strand: Reverse

Name: braD [H]

Synonym: RD1_2165

Alternate gene names: 110679439

Gene position: 2065320-2063311 (Counterclockwise)

Preceding gene: 110679440

Following gene: 110679438

Centisome position: 49.97

GC content: 61.49

Gene sequence:

>2010_bases
GTGCCGGACGCTGGCACGCGCCGCCTTCCAGATCCGAAGGATTCTCCCATGATTTCTGTCGTCCTGCGGTGCTGTGCGTG
CCTTCTCATTTGCGCCGCGCTTATAGGTCCTGCGCCGGCGCAGGATAGCCAAGCACCGATCCAGCAGTTGTTGCAAACCC
ATGGTGAGATCATCAAGAAATCATCGCGCCGCACCATCGGACCGGCCATTGATGCGCTTGCAAACAGCGGCATGGTGGAA
GCGCAGAGCATTCTGCAGCGCTGGCAGGACAAGGAGATGTGGTACAATAAATCCACCGGCGTCTTTGTCTTTGCCCAACC
TGCAGAGGGCGATGCGCTGGCGCTGTTCGATGTCGCCGGTGGCGGGGCGCTACCGCAGGGTGACGCAGACGATTACAAAC
AGCTCAAACCCAATTCCGGCATCCGCGCGATGATCGGCGCAGCCCTCGTGCAATTCCAGTTGAACAGCCCTGATCCCGCA
GAACGCGCTGTCGCGCTCAGCGCGATTGAGCGGGATGCGGACCCGTCTCACCTCACTGCCCTGCGCAGCGTCGCCGCTAC
GGAAACCGACCCGGCCCTCAAACTGCGAAAAGAGCGTCTGGAGCGTCTGCTGACCATCCGTTTTGACACGGACGACACCG
CCAGGATCGCCGCGATTGAAAGCTTCTCCGGCGATCTGGGCGTGGACCTGCGCGCCGCGCTGAACCCTCTGGTCGCGACC
CGCATTGAGGTCGGCGAGACCGTGCCTGATGGCGCCCGCGCGCTGGAGGTTGGCAGCGATGCCCTGCCCCGTGTCACCGC
CTATGACGCTCTGATCGCACGGGACCTCGCGCCGCCGCGTGTGTCCACAGACAACATGCGCGATACGCTGATCGCCAATA
TCGACGCAGGCCAGATCGCAGGTGTTCAGGTCGCCTCTTTGAACACGGATGACGCGCGGGCCGCCGCCTATGCGCTGCTG
GCCGCAAGCGGGCTGGCACAACCGCTGGTGACAGAGGCCGACATCGACGCGGCACTTGCGTCGTTCAGGTTTTTCGAGGT
TTTCACCGGCGCGCCCCTGCCCGTCGCGCAAGCGGCCCAAACCGCGCTTGAGCAGATCGAAACCCGTGTCGCCGTCAACC
AGACCGCTGATCTGGCGCTGGATGCGCTGTCGCTGGCGTCGATCTATTTTCTGGCCGCCATCGGGCTTGCCATCACCTTT
GGCGTGATGGGCGTGATCAACATGGCGCACGGGGAATTCATCATGATGGGGGCCTATACAGGCTATGTGGTGCAGCTGTT
CATCCCCGATTATACGCTGTCGATCCTGCTGGCCATTCCGCTCGCCTTTATGGTGACTTTTGGCGCGGGTGTCGCGATGG
AGCGTTTGGTGATCCGTTGGCTCTACCATCGCCCGCTGGAGACCTTGCTGGCCACTTTCGGGGTCTCGATTGCGCTGCAA
CAGCTGGCCAAGAACATCTTTGGCACGCAGGCCCGCCCGCTGACCGCCCCCGGCTGGCTGGATGGATCATGGGTGATCAA
CGATATCGTGTCGATCAGCTATATTCGCATCGCGATCTTCTTCCTCGCCTTGATGTTTCTGGCGCTGTTCCTTTTCGTGA
TGAAAAGAACAAGACTGGGGCTTGAGGTGCGCGCGGTGACGCAAAACCCGCGCATGGCCGCCTCCATGGGCATCAACCCG
GACAGGATCAACATGCTGACCTTTGGCTTTGGCTCGGGCATCGCGGGGATCGCGGGCGTGGCCATCGGGCTTTATTCAAA
AGTCACCTCCGAGATGGGCAGCGAATACATCGTGCAGAGCTTCATGACTGTTGTTGTGGGTGGCGTTGGCAACATCTGGG
GCACGCTGCTCGGGGCCACGATGGTGGGCACGCTGCAAAAAGGGATCGAGTGGCTGAACCCCTCAAACACATTGGCGGCG
CAGACCTATATGATCCTGTTTATCATCCTCTTTATACAGTTCCGGCCCCGCGGCATCATCGCGCTCAAAGGCCGGGCGGC
GGAGGCCTGA

Upstream 100 bases:

>100_bases
ATTGGCAAGAACTGGGCTGCGGTATGTTTAACACCGAGACCAATTCCTGCGTGCAGATCAAATCCAACTACTGATCCGCC
CTGAACGCTGAACCGGGCGC

Downstream 100 bases:

>100_bases
ACCATGGCAGACATCGCCCTCGCCCCCCCGCACAAACCCTTCGTGGCGCGCCATCCTTCGGTCCTGATTTTCCTCGGGCT
TCTGGCGCTCTTTACCCTCG

Product: branched-chain amino acid ABC transporter, permease protein, putative

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MPDAGTRRLPDPKDSPMISVVLRCCACLLICAALIGPAPAQDSQAPIQQLLQTHGEIIKKSSRRTIGPAIDALANSGMVE
AQSILQRWQDKEMWYNKSTGVFVFAQPAEGDALALFDVAGGGALPQGDADDYKQLKPNSGIRAMIGAALVQFQLNSPDPA
ERAVALSAIERDADPSHLTALRSVAATETDPALKLRKERLERLLTIRFDTDDTARIAAIESFSGDLGVDLRAALNPLVAT
RIEVGETVPDGARALEVGSDALPRVTAYDALIARDLAPPRVSTDNMRDTLIANIDAGQIAGVQVASLNTDDARAAAYALL
AASGLAQPLVTEADIDAALASFRFFEVFTGAPLPVAQAAQTALEQIETRVAVNQTADLALDALSLASIYFLAAIGLAITF
GVMGVINMAHGEFIMMGAYTGYVVQLFIPDYTLSILLAIPLAFMVTFGAGVAMERLVIRWLYHRPLETLLATFGVSIALQ
QLAKNIFGTQARPLTAPGWLDGSWVINDIVSISYIRIAIFFLALMFLALFLFVMKRTRLGLEVRAVTQNPRMAASMGINP
DRINMLTFGFGSGIAGIAGVAIGLYSKVTSEMGSEYIVQSFMTVVVGGVGNIWGTLLGATMVGTLQKGIEWLNPSNTLAA
QTYMILFIILFIQFRPRGIIALKGRAAEA

Sequences:

>Translated_669_residues
MPDAGTRRLPDPKDSPMISVVLRCCACLLICAALIGPAPAQDSQAPIQQLLQTHGEIIKKSSRRTIGPAIDALANSGMVE
AQSILQRWQDKEMWYNKSTGVFVFAQPAEGDALALFDVAGGGALPQGDADDYKQLKPNSGIRAMIGAALVQFQLNSPDPA
ERAVALSAIERDADPSHLTALRSVAATETDPALKLRKERLERLLTIRFDTDDTARIAAIESFSGDLGVDLRAALNPLVAT
RIEVGETVPDGARALEVGSDALPRVTAYDALIARDLAPPRVSTDNMRDTLIANIDAGQIAGVQVASLNTDDARAAAYALL
AASGLAQPLVTEADIDAALASFRFFEVFTGAPLPVAQAAQTALEQIETRVAVNQTADLALDALSLASIYFLAAIGLAITF
GVMGVINMAHGEFIMMGAYTGYVVQLFIPDYTLSILLAIPLAFMVTFGAGVAMERLVIRWLYHRPLETLLATFGVSIALQ
QLAKNIFGTQARPLTAPGWLDGSWVINDIVSISYIRIAIFFLALMFLALFLFVMKRTRLGLEVRAVTQNPRMAASMGINP
DRINMLTFGFGSGIAGIAGVAIGLYSKVTSEMGSEYIVQSFMTVVVGGVGNIWGTLLGATMVGTLQKGIEWLNPSNTLAA
QTYMILFIILFIQFRPRGIIALKGRAAEA
>Mature_668_residues
PDAGTRRLPDPKDSPMISVVLRCCACLLICAALIGPAPAQDSQAPIQQLLQTHGEIIKKSSRRTIGPAIDALANSGMVEA
QSILQRWQDKEMWYNKSTGVFVFAQPAEGDALALFDVAGGGALPQGDADDYKQLKPNSGIRAMIGAALVQFQLNSPDPAE
RAVALSAIERDADPSHLTALRSVAATETDPALKLRKERLERLLTIRFDTDDTARIAAIESFSGDLGVDLRAALNPLVATR
IEVGETVPDGARALEVGSDALPRVTAYDALIARDLAPPRVSTDNMRDTLIANIDAGQIAGVQVASLNTDDARAAAYALLA
ASGLAQPLVTEADIDAALASFRFFEVFTGAPLPVAQAAQTALEQIETRVAVNQTADLALDALSLASIYFLAAIGLAITFG
VMGVINMAHGEFIMMGAYTGYVVQLFIPDYTLSILLAIPLAFMVTFGAGVAMERLVIRWLYHRPLETLLATFGVSIALQQ
LAKNIFGTQARPLTAPGWLDGSWVINDIVSISYIRIAIFFLALMFLALFLFVMKRTRLGLEVRAVTQNPRMAASMGINPD
RINMLTFGFGSGIAGIAGVAIGLYSKVTSEMGSEYIVQSFMTVVVGGVGNIWGTLLGATMVGTLQKGIEWLNPSNTLAAQ
TYMILFIILFIQFRPRGIIALKGRAAEA

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=258, Percent_Identity=30.2325581395349, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 71501; Mature: 71370

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDAGTRRLPDPKDSPMISVVLRCCACLLICAALIGPAPAQDSQAPIQQLLQTHGEIIKK
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SSRRTIGPAIDALANSGMVEAQSILQRWQDKEMWYNKSTGVFVFAQPAEGDALALFDVAG
CCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCCEEEEEEECC
GGALPQGDADDYKQLKPNSGIRAMIGAALVQFQLNSPDPAERAVALSAIERDADPSHLTA
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHHHH
LRSVAATETDPALKLRKERLERLLTIRFDTDDTARIAAIESFSGDLGVDLRAALNPLVAT
HHHHHCCCCCHHHHHHHHHHHHHEEEEECCCCCHHEEEEHHCCCCCCCCHHHHHHHHHHH
RIEVGETVPDGARALEVGSDALPRVTAYDALIARDLAPPRVSTDNMRDTLIANIDAGQIA
HHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHEEEECCCCCCC
GVQVASLNTDDARAAAYALLAASGLAQPLVTEADIDAALASFRFFEVFTGAPLPVAQAAQ
CEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TALEQIETRVAVNQTADLALDALSLASIYFLAAIGLAITFGVMGVINMAHGEFIMMGAYT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GYVVQLFIPDYTLSILLAIPLAFMVTFGAGVAMERLVIRWLYHRPLETLLATFGVSIALQ
CEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QLAKNIFGTQARPLTAPGWLDGSWVINDIVSISYIRIAIFFLALMFLALFLFVMKRTRLG
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEVRAVTQNPRMAASMGINPDRINMLTFGFGSGIAGIAGVAIGLYSKVTSEMGSEYIVQS
CEEEEECCCCCHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMTVVVGGVGNIWGTLLGATMVGTLQKGIEWLNPSNTLAAQTYMILFIILFIQFRPRGII
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
ALKGRAAEA
EECCCCCCC
>Mature Secondary Structure 
PDAGTRRLPDPKDSPMISVVLRCCACLLICAALIGPAPAQDSQAPIQQLLQTHGEIIKK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SSRRTIGPAIDALANSGMVEAQSILQRWQDKEMWYNKSTGVFVFAQPAEGDALALFDVAG
CCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCCEEEEEEECC
GGALPQGDADDYKQLKPNSGIRAMIGAALVQFQLNSPDPAERAVALSAIERDADPSHLTA
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHHHH
LRSVAATETDPALKLRKERLERLLTIRFDTDDTARIAAIESFSGDLGVDLRAALNPLVAT
HHHHHCCCCCHHHHHHHHHHHHHEEEEECCCCCHHEEEEHHCCCCCCCCHHHHHHHHHHH
RIEVGETVPDGARALEVGSDALPRVTAYDALIARDLAPPRVSTDNMRDTLIANIDAGQIA
HHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHEEEECCCCCCC
GVQVASLNTDDARAAAYALLAASGLAQPLVTEADIDAALASFRFFEVFTGAPLPVAQAAQ
CEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TALEQIETRVAVNQTADLALDALSLASIYFLAAIGLAITFGVMGVINMAHGEFIMMGAYT
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GYVVQLFIPDYTLSILLAIPLAFMVTFGAGVAMERLVIRWLYHRPLETLLATFGVSIALQ
CEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QLAKNIFGTQARPLTAPGWLDGSWVINDIVSISYIRIAIFFLALMFLALFLFVMKRTRLG
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEVRAVTQNPRMAASMGINPDRINMLTFGFGSGIAGIAGVAIGLYSKVTSEMGSEYIVQS
CEEEEECCCCCHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMTVVVGGVGNIWGTLLGATMVGTLQKGIEWLNPSNTLAAQTYMILFIILFIQFRPRGII
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
ALKGRAAEA
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]