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The map label for this gene is ptsP [H]

Identifier: 110679432

GI number: 110679432

Start: 2053861

End: 2056104

Strand: Direct

Name: ptsP [H]

Synonym: RD1_2158

Alternate gene names: 110679432

Gene position: 2053861-2056104 (Clockwise)

Preceding gene: 110679431

Following gene: 110679433

Centisome position: 49.69

GC content: 60.87

Gene sequence:

>2244_bases
GTGGCTGAACGTCTCGAGAGTGAATCGCGCAAACTGCTGGGGCGATTGCGCGATGCGATGGCAGGGCTCGCCGCCGGGCA
GGAACGGCTGGATGAGATTACATCGCTGATCGCGGAAAGCATGGACTGTGACGTCTGTTCCATCTACCTGTTTCGCGATG
CAGAAACGCTGGAGCTATGCGCCACCAAGGGCCTGAACAAAGAGGCCGTGCATAAGACACGCATGAAACTCGGTGAGGGT
CTTGTGGGGCGTGTCGCCAAACAGCGCACCATCGTGAACACGCCCGATGCGCCGCAGGCCAAGGGTTTTCGCTACATGCC
CGAAACCGGTGAAGAGGTTTTCTCCAGTTTCCTCGGTATACCGATCCAGCGCCTTGGTGATGCGTTGGGCGTGCTTGTGG
TGCAGTCGCGCGCGGCGCGGGAGTTTTCCGCAGATGCCGTCTATGCCCTCGAAGTTGTTGCGATGGTACTGGCCGAGATG
ACGGAACTTGGCGCTTTCGTGGGCGAGGGGGCCGCCATGTCGGCGCGTCATTCCCAGCCTGCGATGTTTCCGGGGACCGT
CGGGCAGGAAGGCGCTGCGGAGGGTCATGTCTGGCTGCATGAACCCCGCGTTGTCGTAACCAACCCGATCGCCGATGACC
CGGTGCGCGAGGCAGAGCGTCTTGACGAAGCGGTCGAAGAGTTGCGTGTCGGCGTTGACAAGATGATGCAGATTGCCGGT
GGGCAGGACAAGGATCAGCGTCAGGTGCTCGAAGCCTACCGCATGTTTGCCAACTCCAAGGGGTGGATGCGGCGCATGCA
GGAGGATATCGCAAACGGTCTGTCCGCCGAAGCCGCCGTCGAAAAGGAGCAATCGACCGCGCGTGCGCGCATGTCACAGA
TCACGGACGGATACCTGCGCGAGCGCTTGAGTGACCTTGATGATCTGTCAAACCGGCTGCTGCGCATTCTGACCGGGCAG
GGTGCCGACACAGGCGCCGAGATGCCGGATGATCCGATCCTGATTGCACGCAATATCGGGCCGGCTGAATTACTGGAATA
CGGGCGCAAGCTGAAAGGCATCGTGCTGGAGGAGGGTTCGGTTGGCAGCCACGCCGCGGTGGTCGCGCGCGCACTGGCCA
TTCCGTTGATCGTCCATGCCCAGCGGATCACGACCGAGGCGTTGAATGGCGATCATATCATGGTGGACGGAGAGCAGGGC
ATCGCACACCTGCGACCGGACGAATCCGTTGTCTCTGCGTTTCGCGACAAAATCGCGATGCTGGCCGCCGCGCAGGAACG
CTACGCCTCCATCCGCGAAAAACCCGCACTGACGCAGGACGGGTTCACAGTGGCGCTTAATATGAACGCCGGGCTCATGG
CGGACCTGCCTTCGCTGGTCTCTTCTGGGGCGGAAGGTGTCGGTCTTTTCCGGACCGAATTGCAGTTTCTCGTGCGCAAC
CAGATGCCAAGGCGCTCTGAACTGGTGGCTCTTTATGCCCGCGTGCTTGATGCGGCGCAGGGCAAGCGGGTCGTTTTTCG
AACGCTCGATATCGGCTCCGACAAGGTGCTGCCCTATATGAAGCCGAACGAAGAGCCGAACCCGGCGCTTGGCTGGCGCG
CCATTCGCGTCGGTCTGGACAAGCCGGGCATCATGCGCATGCAGCTTCAGGCGCTCATCCGGGCTGCAAATGGCCGCCCG
CTCACCGTGATGTTTCCCTTTGTGGCGCAAATGGAAGAATATACCGAGGCGCGGCGCCTGATGGATAAAACCGTGGCCGC
CGAAGCGCGACTGGGTCACATTTTGCCTGAAACGATTGAAATCGGCGCAATGCTTGAAACGCCGAGCCTCGCATTCGCCC
CGAACAAATTTTTTGAAAACGTGGATTTTCTGTCGATTGGTGGCAATGACCTCAAGCAGTTTTTCTTTGCGGCGGACCGG
GAAAACGAGCGGGTGCGGCGGCGCTATGACACTTTGAATGTCTCGTTTCTGAGCTTTGTGGAGCGGATTGTGGAGCGTTG
CGAGGCGACCGGAACACCTGTTTCATTCTGCGGCGAAGATGCCGGACGCCCGGTTGAGGCTTTGTGCTTTGCGGCGATGG
GGTTGCGCAGCCTGTCGATGCGGCCTGCCTCCATCGGCCCGGTGAAAAACCTGCTGCGCCGCAGCGATCTGGGTCAGGTC
CGCAAGGTCATCGCAGACGCGCGTCACCGGGGTGAGATGTCCGTGCGACCTGCGGTCATGGAATGGCTGCGCGGGCAGGG
CTGA

Upstream 100 bases:

>100_bases
GGAACTTGCCGTGCAGGCCCTGCATGATGCCTTCGAATTGGAAAAGGCCGCCTGACCGTCACACGCAAAATGGCGTCGCG
CATATGGGAAGGAAGCATAC

Downstream 100 bases:

>100_bases
CCGGGCGGCAGTATTGCCCGCTGCATGGCGTCAACTGAGCCACTGACGAAGCTGGAAAAGGTGGTGACAGACGTGGGTTT
TCTTGGCGATGGCGCGCTGC

Product: phosphoenolpyruvate-protein phosphotransferase, putative

Products: NA

Alternate protein names: Enzyme I-Ntr; Phosphotransferase system, enzyme I [H]

Number of amino acids: Translated: 747; Mature: 746

Protein sequence:

>747_residues
MAERLESESRKLLGRLRDAMAGLAAGQERLDEITSLIAESMDCDVCSIYLFRDAETLELCATKGLNKEAVHKTRMKLGEG
LVGRVAKQRTIVNTPDAPQAKGFRYMPETGEEVFSSFLGIPIQRLGDALGVLVVQSRAAREFSADAVYALEVVAMVLAEM
TELGAFVGEGAAMSARHSQPAMFPGTVGQEGAAEGHVWLHEPRVVVTNPIADDPVREAERLDEAVEELRVGVDKMMQIAG
GQDKDQRQVLEAYRMFANSKGWMRRMQEDIANGLSAEAAVEKEQSTARARMSQITDGYLRERLSDLDDLSNRLLRILTGQ
GADTGAEMPDDPILIARNIGPAELLEYGRKLKGIVLEEGSVGSHAAVVARALAIPLIVHAQRITTEALNGDHIMVDGEQG
IAHLRPDESVVSAFRDKIAMLAAAQERYASIREKPALTQDGFTVALNMNAGLMADLPSLVSSGAEGVGLFRTELQFLVRN
QMPRRSELVALYARVLDAAQGKRVVFRTLDIGSDKVLPYMKPNEEPNPALGWRAIRVGLDKPGIMRMQLQALIRAANGRP
LTVMFPFVAQMEEYTEARRLMDKTVAAEARLGHILPETIEIGAMLETPSLAFAPNKFFENVDFLSIGGNDLKQFFFAADR
ENERVRRRYDTLNVSFLSFVERIVERCEATGTPVSFCGEDAGRPVEALCFAAMGLRSLSMRPASIGPVKNLLRRSDLGQV
RKVIADARHRGEMSVRPAVMEWLRGQG

Sequences:

>Translated_747_residues
MAERLESESRKLLGRLRDAMAGLAAGQERLDEITSLIAESMDCDVCSIYLFRDAETLELCATKGLNKEAVHKTRMKLGEG
LVGRVAKQRTIVNTPDAPQAKGFRYMPETGEEVFSSFLGIPIQRLGDALGVLVVQSRAAREFSADAVYALEVVAMVLAEM
TELGAFVGEGAAMSARHSQPAMFPGTVGQEGAAEGHVWLHEPRVVVTNPIADDPVREAERLDEAVEELRVGVDKMMQIAG
GQDKDQRQVLEAYRMFANSKGWMRRMQEDIANGLSAEAAVEKEQSTARARMSQITDGYLRERLSDLDDLSNRLLRILTGQ
GADTGAEMPDDPILIARNIGPAELLEYGRKLKGIVLEEGSVGSHAAVVARALAIPLIVHAQRITTEALNGDHIMVDGEQG
IAHLRPDESVVSAFRDKIAMLAAAQERYASIREKPALTQDGFTVALNMNAGLMADLPSLVSSGAEGVGLFRTELQFLVRN
QMPRRSELVALYARVLDAAQGKRVVFRTLDIGSDKVLPYMKPNEEPNPALGWRAIRVGLDKPGIMRMQLQALIRAANGRP
LTVMFPFVAQMEEYTEARRLMDKTVAAEARLGHILPETIEIGAMLETPSLAFAPNKFFENVDFLSIGGNDLKQFFFAADR
ENERVRRRYDTLNVSFLSFVERIVERCEATGTPVSFCGEDAGRPVEALCFAAMGLRSLSMRPASIGPVKNLLRRSDLGQV
RKVIADARHRGEMSVRPAVMEWLRGQG
>Mature_746_residues
AERLESESRKLLGRLRDAMAGLAAGQERLDEITSLIAESMDCDVCSIYLFRDAETLELCATKGLNKEAVHKTRMKLGEGL
VGRVAKQRTIVNTPDAPQAKGFRYMPETGEEVFSSFLGIPIQRLGDALGVLVVQSRAAREFSADAVYALEVVAMVLAEMT
ELGAFVGEGAAMSARHSQPAMFPGTVGQEGAAEGHVWLHEPRVVVTNPIADDPVREAERLDEAVEELRVGVDKMMQIAGG
QDKDQRQVLEAYRMFANSKGWMRRMQEDIANGLSAEAAVEKEQSTARARMSQITDGYLRERLSDLDDLSNRLLRILTGQG
ADTGAEMPDDPILIARNIGPAELLEYGRKLKGIVLEEGSVGSHAAVVARALAIPLIVHAQRITTEALNGDHIMVDGEQGI
AHLRPDESVVSAFRDKIAMLAAAQERYASIREKPALTQDGFTVALNMNAGLMADLPSLVSSGAEGVGLFRTELQFLVRNQ
MPRRSELVALYARVLDAAQGKRVVFRTLDIGSDKVLPYMKPNEEPNPALGWRAIRVGLDKPGIMRMQLQALIRAANGRPL
TVMFPFVAQMEEYTEARRLMDKTVAAEARLGHILPETIEIGAMLETPSLAFAPNKFFENVDFLSIGGNDLKQFFFAADRE
NERVRRRYDTLNVSFLSFVERIVERCEATGTPVSFCGEDAGRPVEALCFAAMGLRSLSMRPASIGPVKNLLRRSDLGQVR
KVIADARHRGEMSVRPAVMEWLRGQG

Specific function: Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. Enzyme I- Ntr transfers the phosphoryl group from phosphoenolpyruvate (PEP)

COG id: COG3605

COG function: function code T; Signal transduction protein containing GAF and PtsI domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GAF domain [H]

Homologues:

Organism=Escherichia coli, GI1789193, Length=722, Percent_Identity=33.3795013850416, Blast_Score=331, Evalue=1e-91,
Organism=Escherichia coli, GI1788756, Length=445, Percent_Identity=33.7078651685393, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI1788726, Length=549, Percent_Identity=30.2367941712204, Blast_Score=235, Evalue=8e-63,
Organism=Escherichia coli, GI48994992, Length=486, Percent_Identity=31.0699588477366, Blast_Score=234, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003018
- InterPro:   IPR008279
- InterPro:   IPR006318
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR008731
- InterPro:   IPR015813 [H]

Pfam domain/function: PF01590 GAF; PF05524 PEP-utilisers_N; PF00391 PEP-utilizers; PF02896 PEP-utilizers_C [H]

EC number: =2.7.3.9 [H]

Molecular weight: Translated: 82072; Mature: 81941

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERLESESRKLLGRLRDAMAGLAAGQERLDEITSLIAESMDCDVCSIYLFRDAETLELC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHH
ATKGLNKEAVHKTRMKLGEGLVGRVAKQRTIVNTPDAPQAKGFRYMPETGEEVFSSFLGI
HHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
PIQRLGDALGVLVVQSRAAREFSADAVYALEVVAMVLAEMTELGAFVGEGAAMSARHSQP
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AMFPGTVGQEGAAEGHVWLHEPRVVVTNPIADDPVREAERLDEAVEELRVGVDKMMQIAG
CCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQDKDQRQVLEAYRMFANSKGWMRRMQEDIANGLSAEAAVEKEQSTARARMSQITDGYLR
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERLSDLDDLSNRLLRILTGQGADTGAEMPDDPILIARNIGPAELLEYGRKLKGIVLEEGS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCEEEECCC
VGSHAAVVARALAIPLIVHAQRITTEALNGDHIMVDGEQGIAHLRPDESVVSAFRDKIAM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LAAAQERYASIREKPALTQDGFTVALNMNAGLMADLPSLVSSGAEGVGLFRTELQFLVRN
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QMPRRSELVALYARVLDAAQGKRVVFRTLDIGSDKVLPYMKPNEEPNPALGWRAIRVGLD
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCC
KPGIMRMQLQALIRAANGRPLTVMFPFVAQMEEYTEARRLMDKTVAAEARLGHILPETIE
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IGAMLETPSLAFAPNKFFENVDFLSIGGNDLKQFFFAADRENERVRRRYDTLNVSFLSFV
HCEEECCCCCEECCHHHHCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHH
ERIVERCEATGTPVSFCGEDAGRPVEALCFAAMGLRSLSMRPASIGPVKNLLRRSDLGQV
HHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHH
RKVIADARHRGEMSVRPAVMEWLRGQG
HHHHHHHHHCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
AERLESESRKLLGRLRDAMAGLAAGQERLDEITSLIAESMDCDVCSIYLFRDAETLELC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHH
ATKGLNKEAVHKTRMKLGEGLVGRVAKQRTIVNTPDAPQAKGFRYMPETGEEVFSSFLGI
HHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
PIQRLGDALGVLVVQSRAAREFSADAVYALEVVAMVLAEMTELGAFVGEGAAMSARHSQP
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AMFPGTVGQEGAAEGHVWLHEPRVVVTNPIADDPVREAERLDEAVEELRVGVDKMMQIAG
CCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GQDKDQRQVLEAYRMFANSKGWMRRMQEDIANGLSAEAAVEKEQSTARARMSQITDGYLR
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ERLSDLDDLSNRLLRILTGQGADTGAEMPDDPILIARNIGPAELLEYGRKLKGIVLEEGS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCEEEECCC
VGSHAAVVARALAIPLIVHAQRITTEALNGDHIMVDGEQGIAHLRPDESVVSAFRDKIAM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LAAAQERYASIREKPALTQDGFTVALNMNAGLMADLPSLVSSGAEGVGLFRTELQFLVRN
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QMPRRSELVALYARVLDAAQGKRVVFRTLDIGSDKVLPYMKPNEEPNPALGWRAIRVGLD
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCC
KPGIMRMQLQALIRAANGRPLTVMFPFVAQMEEYTEARRLMDKTVAAEARLGHILPETIE
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IGAMLETPSLAFAPNKFFENVDFLSIGGNDLKQFFFAADRENERVRRRYDTLNVSFLSFV
HCEEECCCCCEECCHHHHCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHH
ERIVERCEATGTPVSFCGEDAGRPVEALCFAAMGLRSLSMRPASIGPVKNLLRRSDLGQV
HHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHH
RKVIADARHRGEMSVRPAVMEWLRGQG
HHHHHHHHHCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 7896715; 8973315 [H]