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The map label for this gene is ctaE [H]

Identifier: 110679414

GI number: 110679414

Start: 2037386

End: 2038207

Strand: Direct

Name: ctaE [H]

Synonym: RD1_2139

Alternate gene names: 110679414

Gene position: 2037386-2038207 (Clockwise)

Preceding gene: 110679413

Following gene: 110679415

Centisome position: 49.29

GC content: 56.69

Gene sequence:

>822_bases
ATGGCGCATGAAAAGAACCATGACTATCACATTTTAAACCCCTCGATCTGGCCGCTGCTTGGCTCTGTCGGGGCATTTTT
CATGCTCTTTGGCGCTGTGCTGTGGATGCAGGGGCAGTTTCCGTGGATGTTCCTGATGGGCTTTGTCGCCGTGCTCTACG
TGATGTTCGGGTGGTGGTCCGAGGTGGTCGCGGAAAGCAAAATGGGGGATCACACGCCGGTCGTGCGGATCGGGCTGCGG
TATGGCTTCATCCTCTTCATCATGTCCGAGGTGATGTTCTTTGCCGCGTGGTTCTGGTCGTTCTTCAAACACGCCATCTA
CCCGATGAGCGGATATGCAGGCACCGAATATGTTCAGCCGGAAATCTACCATGTGGATGCGTTCCACCTGCCGCTGATCA
ACACGCTGGTCCTGCTTTTGTCGGGCTGTGCGGTCACATGGGCGCACCACGCGCTGGTGCATGAGAACAACCGCCGCGAT
TTGATCTGGGGTCTTGCGATCTCGATCATCCTCGGGGTTTTGTTCACCTTCCTGCAGGCCTACGAATACTCTTACCTGCT
CTACAAGGGCTGGGAGTTTGGCGGCGACAAGTTCTTCTCGAACTTCTTCATGGCCACCGGCTTCCACGGGCTGCATGTCA
TCATCGGCACGATTTTCCTGACCGTCTGTCTGGTGCGTGCCATCAAGGGGCATTTCACCCCCGAGAAACATGTCGGCTTT
GAGGCGGCGGCCTGGTACTGGCACTTTGTTGACGTGGTCTGGTTGTTCCTCTTCTTCGCCGTCTACATCTACGGGGTCAG
CGTGATGCCCGGCGCGCACTAG

Upstream 100 bases:

>100_bases
TACGAAATCGACCTGCCCGAAGAATATGCCGACGCGCAGGACATCGAAGAAAATTCAGACACAAGTCTGAACTGACCAAC
ATAAGGTAAGGGACGAAACC

Downstream 100 bases:

>100_bases
GCGTTCCTTCAGGGTTTGAAATCAAAGCGCGCGTTTTTTCGCGCGCTTTTCTTTGGGAAAGGCAGCACCGAATGGGCCGG
TTGGTGTTTCTGGTGGTTAT

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MAHEKNHDYHILNPSIWPLLGSVGAFFMLFGAVLWMQGQFPWMFLMGFVAVLYVMFGWWSEVVAESKMGDHTPVVRIGLR
YGFILFIMSEVMFFAAWFWSFFKHAIYPMSGYAGTEYVQPEIYHVDAFHLPLINTLVLLLSGCAVTWAHHALVHENNRRD
LIWGLAISIILGVLFTFLQAYEYSYLLYKGWEFGGDKFFSNFFMATGFHGLHVIIGTIFLTVCLVRAIKGHFTPEKHVGF
EAAAWYWHFVDVVWLFLFFAVYIYGVSVMPGAH

Sequences:

>Translated_273_residues
MAHEKNHDYHILNPSIWPLLGSVGAFFMLFGAVLWMQGQFPWMFLMGFVAVLYVMFGWWSEVVAESKMGDHTPVVRIGLR
YGFILFIMSEVMFFAAWFWSFFKHAIYPMSGYAGTEYVQPEIYHVDAFHLPLINTLVLLLSGCAVTWAHHALVHENNRRD
LIWGLAISIILGVLFTFLQAYEYSYLLYKGWEFGGDKFFSNFFMATGFHGLHVIIGTIFLTVCLVRAIKGHFTPEKHVGF
EAAAWYWHFVDVVWLFLFFAVYIYGVSVMPGAH
>Mature_272_residues
AHEKNHDYHILNPSIWPLLGSVGAFFMLFGAVLWMQGQFPWMFLMGFVAVLYVMFGWWSEVVAESKMGDHTPVVRIGLRY
GFILFIMSEVMFFAAWFWSFFKHAIYPMSGYAGTEYVQPEIYHVDAFHLPLINTLVLLLSGCAVTWAHHALVHENNRRDL
IWGLAISIILGVLFTFLQAYEYSYLLYKGWEFGGDKFFSNFFMATGFHGLHVIIGTIFLTVCLVRAIKGHFTPEKHVGFE
AAAWYWHFVDVVWLFLFFAVYIYGVSVMPGAH

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=266, Percent_Identity=46.9924812030075, Blast_Score=210, Evalue=1e-54,
Organism=Escherichia coli, GI1786633, Length=188, Percent_Identity=30.3191489361702, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6226542, Length=274, Percent_Identity=34.3065693430657, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31531; Mature: 31400

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AHEKNHDYHILNPSIWPLLGSVGAFFMLFGAVLWMQGQFPWMFLMGFVAVLYVMFGWWS
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EVVAESKMGDHTPVVRIGLRYGFILFIMSEVMFFAAWFWSFFKHAIYPMSGYAGTEYVQP
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EIYHVDAFHLPLINTLVLLLSGCAVTWAHHALVHENNRRDLIWGLAISIILGVLFTFLQA
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
YEYSYLLYKGWEFGGDKFFSNFFMATGFHGLHVIIGTIFLTVCLVRAIKGHFTPEKHVGF
HHHHHHEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCC
EAAAWYWHFVDVVWLFLFFAVYIYGVSVMPGAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]