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The map label for this gene is ruvB

Identifier: 110679370

GI number: 110679370

Start: 1996043

End: 1997065

Strand: Direct

Name: ruvB

Synonym: RD1_2090

Alternate gene names: 110679370

Gene position: 1996043-1997065 (Clockwise)

Preceding gene: 110679369

Following gene: 110679371

Centisome position: 48.29

GC content: 63.83

Gene sequence:

>1023_bases
ATGAGCGATATTGATCCGACCGTGCGCGCCGATCCCCTGCCAGAGGATCACGACCGCGCCTTGCGCCCGCAGATGCTGTC
GGAGTTCGTTGGGCAGGCGGAGGCGCGCGCCAACCTCAAGGTGTTCATCGCCTCTGCACGGCAACGCGGCGAGGCCATGG
ATCACACGCTGTTTCACGGCCCCCCCGGTCTGGGCAAGACCACGCTGGCACAGATCATGGCGCGCGAATTGGGCGTCGGG
TTTCGCATGACCAGCGGCCCGGTGCTGGCCAAGGCGGGCGATCTTGCGGCGATCCTGACCAATCTGGAAAAACGCGATGT
GCTTTTTATTGACGAAATCCACAGGCTCAACCCCGCCGTGGAAGAAGTGCTCTATCCCGCGCTGGAGGATTTCGAACTTG
ATCTGGTCATCGGCGAGGGCCCTGCGGCGCGCACGGTGCGAATTGAACTGCAACCCTTTACGCTTGTGGGCGCAACCACG
CGGATGGGGCTGCTGACGACGCCATTGCGCGACCGTTTCGGCATTCCCACGCGGTTGCAGTTCTACACCGAAGATGAGCT
TTTCATCATTGTGGATCGCAACGCGCGCAAACTGGGTGCGCCCGCGGATGAGGGCGGCGCGCGTGAAATTGCGCGCCGGG
CGCGTGGCACGCCCCGGATTGCCGGGCGATTGTTGCGCCGCGTTGTGGATTTCGCAGTCGTTGAGGGCGATGGCCGGGTG
ACACGCGCGCTTGCGGATATGGCGCTGAACCGGTTGGGGGTGGATCATCTGGGCCTTGATGGCGCGGACCGGCGCTATTT
GCGGCTGATCGCGGAAAACTATGGCGGCGGACCTGTGGGCATTGAAACGATGAGCGCGGCCCTCAGCGAAAGCCGCGATG
CGCTCGAAGAGGTCATCGAACCCTTCTTGTTGCAGCAGGGGTTGATCCAGCGCACGCCGCGCGGGCGCATGCTGGCGCAA
AAGGGCTGGACGCATCTGGGCCTTGACGCGCCGCGCGCCCAGACGGATTTGTTCGAGGGATAA

Upstream 100 bases:

>100_bases
GGCAGGTGAGTTGCCCGACGCAGAAACGCCCGATCTGATCCGGGCGGCATTGAAACGGCTCGCCCCCAAAGGTTAGGCTG
GGCCAGATGCAGGATACCTC

Downstream 100 bases:

>100_bases
GCGGCGCCTGCGCGTGCCGCCAAGCAGGAGACAGCAGCCTTTATGATGGATGCCAGCGAGATCGAAGCGCTTTTTACGCG
CAGCGGAGGTCAGTTCGCCT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSDIDPTVRADPLPEDHDRALRPQMLSEFVGQAEARANLKVFIASARQRGEAMDHTLFHGPPGLGKTTLAQIMARELGVG
FRMTSGPVLAKAGDLAAILTNLEKRDVLFIDEIHRLNPAVEEVLYPALEDFELDLVIGEGPAARTVRIELQPFTLVGATT
RMGLLTTPLRDRFGIPTRLQFYTEDELFIIVDRNARKLGAPADEGGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGRV
TRALADMALNRLGVDHLGLDGADRRYLRLIAENYGGGPVGIETMSAALSESRDALEEVIEPFLLQQGLIQRTPRGRMLAQ
KGWTHLGLDAPRAQTDLFEG

Sequences:

>Translated_340_residues
MSDIDPTVRADPLPEDHDRALRPQMLSEFVGQAEARANLKVFIASARQRGEAMDHTLFHGPPGLGKTTLAQIMARELGVG
FRMTSGPVLAKAGDLAAILTNLEKRDVLFIDEIHRLNPAVEEVLYPALEDFELDLVIGEGPAARTVRIELQPFTLVGATT
RMGLLTTPLRDRFGIPTRLQFYTEDELFIIVDRNARKLGAPADEGGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGRV
TRALADMALNRLGVDHLGLDGADRRYLRLIAENYGGGPVGIETMSAALSESRDALEEVIEPFLLQQGLIQRTPRGRMLAQ
KGWTHLGLDAPRAQTDLFEG
>Mature_339_residues
SDIDPTVRADPLPEDHDRALRPQMLSEFVGQAEARANLKVFIASARQRGEAMDHTLFHGPPGLGKTTLAQIMARELGVGF
RMTSGPVLAKAGDLAAILTNLEKRDVLFIDEIHRLNPAVEEVLYPALEDFELDLVIGEGPAARTVRIELQPFTLVGATTR
MGLLTTPLRDRFGIPTRLQFYTEDELFIIVDRNARKLGAPADEGGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGRVT
RALADMALNRLGVDHLGLDGADRRYLRLIAENYGGGPVGIETMSAALSESRDALEEVIEPFLLQQGLIQRTPRGRMLAQK
GWTHLGLDAPRAQTDLFEG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=320, Percent_Identity=59.375, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_ROSDO (Q168A2)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682377.1
- ProteinModelPortal:   Q168A2
- SMR:   Q168A2
- STRING:   Q168A2
- GeneID:   4196638
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2090
- NMPDR:   fig|375451.6.peg.1952
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q168A2
- ProtClustDB:   PRK00080
- BioCyc:   RDEN375451:RD1_2090-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37352; Mature: 37221

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIDPTVRADPLPEDHDRALRPQMLSEFVGQAEARANLKVFIASARQRGEAMDHTLFHG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCHHHHHHHCCC
PPGLGKTTLAQIMARELGVGFRMTSGPVLAKAGDLAAILTNLEKRDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEEECCCCCEECCCHHHHHHHCCCCCCEEHHHHHHHCCHHH
EEVLYPALEDFELDLVIGEGPAARTVRIELQPFTLVGATTRMGLLTTPLRDRFGIPTRLQ
HHHHHHHHCCCEEEEEECCCCCCEEEEEEECCEEEECCHHHCCCEECCHHHHCCCCCEEE
FYTEDELFIIVDRNARKLGAPADEGGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGRV
EEECCCEEEEECCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCHH
TRALADMALNRLGVDHLGLDGADRRYLRLIAENYGGGPVGIETMSAALSESRDALEEVIE
HHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
PFLLQQGLIQRTPRGRMLAQKGWTHLGLDAPRAQTDLFEG
HHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
SDIDPTVRADPLPEDHDRALRPQMLSEFVGQAEARANLKVFIASARQRGEAMDHTLFHG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHCCHHHHHHHCCC
PPGLGKTTLAQIMARELGVGFRMTSGPVLAKAGDLAAILTNLEKRDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEEECCCCCEECCCHHHHHHHCCCCCCEEHHHHHHHCCHHH
EEVLYPALEDFELDLVIGEGPAARTVRIELQPFTLVGATTRMGLLTTPLRDRFGIPTRLQ
HHHHHHHHCCCEEEEEECCCCCCEEEEEEECCEEEECCHHHCCCEECCHHHHCCCCCEEE
FYTEDELFIIVDRNARKLGAPADEGGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGRV
EEECCCEEEEECCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCHH
TRALADMALNRLGVDHLGLDGADRRYLRLIAENYGGGPVGIETMSAALSESRDALEEVIE
HHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
PFLLQQGLIQRTPRGRMLAQKGWTHLGLDAPRAQTDLFEG
HHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA