Click here to switch to the map view.

The map label for this gene is ruvA

Identifier: 110679369

GI number: 110679369

Start: 1995362

End: 1996018

Strand: Direct

Name: ruvA

Synonym: RD1_2089

Alternate gene names: 110679369

Gene position: 1995362-1996018 (Clockwise)

Preceding gene: 110679368

Following gene: 110679370

Centisome position: 48.28

GC content: 63.77

Gene sequence:

>657_bases
ATGATTGGCAAGATCACGGGCCGACTTGAATACCGCGCGAGCGATCATGTGCTGATTGATGTGCGCGGGGTCGGGTATCT
GGTCTTTTGCTCGGAACGTACATTGGCGGCTCTGCCGGGTGTGGGCGAGGTTGTCGCGCTATATACGGACCTGCTGGTGC
GCGAGGACGTGATGCAGCTTTTCGGTTTCACCACGTTGACGGAAAAGGAATGGCACCGGCTGCTGACCTCTGTGCAGGGG
GTCGGGGCCAAGGCGTCGCTTGCGATCCTCGGCACCTTGGGAGCGGATGGCGTCAGCCGGGCCATTGCGCTGGGGGACTG
GAACGCGGTCAAGGCGGCCAAGGGGGTCGGTCCAAAGATCGCCCAACGCGTGGTTCTGGACCTCAAGGACAAGGCCCCCA
GCGTGATGGGTATGAGCGACACGCAAGCCACGGTGGCTGCTCAGTCGTCAGATGCGGTCATCGAAACGCGCGCCGCACCA
AGCCCCGTTGTCCAAAACCCGTCGGCGCAGGCTGAGGCCCTGTCGGCGCTATCCAATCTGGGTTATGCTCCGGGTGATGC
GGCCGCCGCCGTGGCGCAGGCGGCAGGTGAGTTGCCCGACGCAGAAACGCCCGATCTGATCCGGGCGGCATTGAAACGGC
TCGCCCCCAAAGGTTAG

Upstream 100 bases:

>100_bases
TCAAAAGCCCGGATGCGGCGGATGCTTTGGCGATTGCCATCTGTCATGCACATCACGGGGGGGCGGCTGGTTTGGGCGCG
GCAATTGCAAAGGCAACGGC

Downstream 100 bases:

>100_bases
GCTGGGCCAGATGCAGGATACCTCATGAGCGATATTGATCCGACCGTGCGCGCCGATCCCCTGCCAGAGGATCACGACCG
CGCCTTGCGCCCGCAGATGC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MIGKITGRLEYRASDHVLIDVRGVGYLVFCSERTLAALPGVGEVVALYTDLLVREDVMQLFGFTTLTEKEWHRLLTSVQG
VGAKASLAILGTLGADGVSRAIALGDWNAVKAAKGVGPKIAQRVVLDLKDKAPSVMGMSDTQATVAAQSSDAVIETRAAP
SPVVQNPSAQAEALSALSNLGYAPGDAAAAVAQAAGELPDAETPDLIRAALKRLAPKG

Sequences:

>Translated_218_residues
MIGKITGRLEYRASDHVLIDVRGVGYLVFCSERTLAALPGVGEVVALYTDLLVREDVMQLFGFTTLTEKEWHRLLTSVQG
VGAKASLAILGTLGADGVSRAIALGDWNAVKAAKGVGPKIAQRVVLDLKDKAPSVMGMSDTQATVAAQSSDAVIETRAAP
SPVVQNPSAQAEALSALSNLGYAPGDAAAAVAQAAGELPDAETPDLIRAALKRLAPKG
>Mature_218_residues
MIGKITGRLEYRASDHVLIDVRGVGYLVFCSERTLAALPGVGEVVALYTDLLVREDVMQLFGFTTLTEKEWHRLLTSVQG
VGAKASLAILGTLGADGVSRAIALGDWNAVKAAKGVGPKIAQRVVLDLKDKAPSVMGMSDTQATVAAQSSDAVIETRAAP
SPVVQNPSAQAEALSALSNLGYAPGDAAAAVAQAAGELPDAETPDLIRAALKRLAPKG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=212, Percent_Identity=33.4905660377358, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_ROSDO (Q168A3)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682376.1
- ProteinModelPortal:   Q168A3
- SMR:   Q168A3
- STRING:   Q168A3
- GeneID:   4196637
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_2089
- NMPDR:   fig|375451.6.peg.1951
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   YKTAMSI
- ProtClustDB:   PRK00116
- BioCyc:   RDEN375451:RD1_2089-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22544; Mature: 22544

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKITGRLEYRASDHVLIDVRGVGYLVFCSERTLAALPGVGEVVALYTDLLVREDVMQL
CCCCCCCEEEEECCCEEEEEECCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
FGFTTLTEKEWHRLLTSVQGVGAKASLAILGTLGADGVSRAIALGDWNAVKAAKGVGPKI
HCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHEEEECCCHHHHHHCCCCHHH
AQRVVLDLKDKAPSVMGMSDTQATVAAQSSDAVIETRAAPSPVVQNPSAQAEALSALSNL
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHC
GYAPGDAAAAVAQAAGELPDAETPDLIRAALKRLAPKG
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIGKITGRLEYRASDHVLIDVRGVGYLVFCSERTLAALPGVGEVVALYTDLLVREDVMQL
CCCCCCCEEEEECCCEEEEEECCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
FGFTTLTEKEWHRLLTSVQGVGAKASLAILGTLGADGVSRAIALGDWNAVKAAKGVGPKI
HCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHEEEECCCHHHHHHCCCCHHH
AQRVVLDLKDKAPSVMGMSDTQATVAAQSSDAVIETRAAPSPVVQNPSAQAEALSALSNL
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHC
GYAPGDAAAAVAQAAGELPDAETPDLIRAALKRLAPKG
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA