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The map label for this gene is yfhC [C]

Identifier: 110679276

GI number: 110679276

Start: 1904015

End: 1904482

Strand: Direct

Name: yfhC [C]

Synonym: RD1_1993

Alternate gene names: 110679276

Gene position: 1904015-1904482 (Clockwise)

Preceding gene: 110679259

Following gene: 110679278

Centisome position: 46.07

GC content: 63.89

Gene sequence:

>468_bases
TTGCGTGCAACTAGGCCCATGCAGTTCAACACGCATATGGAAGCGGCCCTCTCTGAGGCGCGCGCGGCGGCCAAACGCGG
AGAGGTCCCGGTCGGCGCTGTCATCGTGGCACCGGATGGCGCGATCATTGCCGCTGCGGGCAATCAGACCCGTGCGGACC
ATGATCCGACCGCACATGCCGAAATCCTCGCGATCCGCAGGGCCTGCGCGGTGCTGGGCAGTGAGCGTCTGTTGGATCAT
GCGCTTTATGTGACGCTTGAGCCTTGTGCGATGTGTGCGGCAGCGATTTCGGCGGCCCGTATTTCGCGGCTCTATTACGG
GGCCAGTGATCCCAAATCGGGGGGGGTGGCGCAGGGGGCGCGCGTGTTCAGCCATCCGCAATGCCATCATGCACCCGAAG
TATTTGACGGCATCGCCGCTGCGGAATCCGAGGCGATGCTCAGGGGATTTTTTACCGCGCGGCGCTAG

Upstream 100 bases:

>100_bases
CGCGGCTGAGGACTTTGGCAATGCGGTCGCCCTGTGGCGTGAGTTCAGAGGTCATGGGGCGGGGCATAGCCTGTTTGCGG
CCCTTGCGAAAGAGAACAGT

Downstream 100 bases:

>100_bases
GCCATGCTCAGAACCTTATCGGCGTCATGACCTGCGGCTCGATCACATCGACATCCGGCAGGGCGTCGATGAGGTCCGTT
GCGGATTGCTCCAGCAGATC

Product: cytidine and deoxycytidylate deaminase family protein

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRATRPMQFNTHMEAALSEARAAAKRGEVPVGAVIVAPDGAIIAAAGNQTRADHDPTAHAEILAIRRACAVLGSERLLDH
ALYVTLEPCAMCAAAISAARISRLYYGASDPKSGGVAQGARVFSHPQCHHAPEVFDGIAAAESEAMLRGFFTARR

Sequences:

>Translated_155_residues
MRATRPMQFNTHMEAALSEARAAAKRGEVPVGAVIVAPDGAIIAAAGNQTRADHDPTAHAEILAIRRACAVLGSERLLDH
ALYVTLEPCAMCAAAISAARISRLYYGASDPKSGGVAQGARVFSHPQCHHAPEVFDGIAAAESEAMLRGFFTARR
>Mature_155_residues
MRATRPMQFNTHMEAALSEARAAAKRGEVPVGAVIVAPDGAIIAAAGNQTRADHDPTAHAEILAIRRACAVLGSERLLDH
ALYVTLEPCAMCAAAISAARISRLYYGASDPKSGGVAQGARVFSHPQCHHAPEVFDGIAAAESEAMLRGFFTARR

Specific function: Mutation In This Protein Makes E.Coli Resistant To The Toxic Proteins Encoded By The Gef Gene Family. [C]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=147, Percent_Identity=31.9727891156463, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=45.4545454545455, Blast_Score=121, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17541138, Length=147, Percent_Identity=36.0544217687075, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=113, Percent_Identity=36.283185840708, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17554608, Length=118, Percent_Identity=36.4406779661017, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=158, Percent_Identity=33.5443037974684, Blast_Score=79, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=36.0544217687075, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 16320; Mature: 16320

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATRPMQFNTHMEAALSEARAAAKRGEVPVGAVIVAPDGAIIAAAGNQTRADHDPTAHA
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCHHH
EILAIRRACAVLGSERLLDHALYVTLEPCAMCAAAISAARISRLYYGASDPKSGGVAQGA
HHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCH
RVFSHPQCHHAPEVFDGIAAAESEAMLRGFFTARR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRATRPMQFNTHMEAALSEARAAAKRGEVPVGAVIVAPDGAIIAAAGNQTRADHDPTAHA
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCHHH
EILAIRRACAVLGSERLLDHALYVTLEPCAMCAAAISAARISRLYYGASDPKSGGVAQGA
HHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCH
RVFSHPQCHHAPEVFDGIAAAESEAMLRGFFTARR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA