Click here to switch to the map view.

The map label for this gene is cocE [H]

Identifier: 110679265

GI number: 110679265

Start: 1893328

End: 1895319

Strand: Reverse

Name: cocE [H]

Synonym: RD1_1980

Alternate gene names: 110679265

Gene position: 1895319-1893328 (Counterclockwise)

Preceding gene: 110679266

Following gene: 110679264

Centisome position: 45.86

GC content: 62.65

Gene sequence:

>1992_bases
ATGGCTGACGACACCTCCTTACGCGACATCGAAGAAGACGCAGATTTCGGCATCACGCTTTCAGACGGATGCAGGCTCTC
TGCGCGATTGTGGAAACCCAAGGATGCAGGGTCAGATCCTGTGCCGGTGATCCTCGAATATCTGCCCTATCGCAAGCGCG
ACGGCACCTGCGCGCGCGACGCGCTGACACACCCGTGGTTCGCGGCGCGCGGCTACGCCTGCCTGCGTGTGGACATACGT
GGCAACGGCGACAGCGAAGGGCTGATGCAGGACGAATACACCCCGCAGGAACTGGCCGATGCGGTCGAAGTCATCAACCA
GATCGCCGCCAAGGACTGGTGCAACGGGCGCGTCGGGATGATGGGGATCAGCTGGGGCGGGTTCAACAGCCTGCAGGTTG
CGGCCCTTGACCCTGCCCCGCTCAAAGCGGTCATCACACTGTGTTCGACCGTGGACCGCTATGCGGATGACATCCATTAC
AAGGGCGGCTGCCTGCTGAATGAAAACCTCGGCTGGGGGTCGACCATGTGGGCCTATTCCAGCCGCGCGCCCGACCCTGC
CCTGCGCCCGGACTGGCGCGCCATGTGGCTGGAACGCCTTGAAAACGAACCATTTTTGCCTGCGGTCTGGCTGCGTCACC
AAAGGCGCGATACCTATTGGCAACACGGCTCGGTCTGCGAGGACTACAGCGCCATCAAGGCCAAGGTACTTGCCATCGGC
GGCTGGGGGGATGCCTATAAAAACGCGGTGCCCCAACTGGTCGAAGGACTGCCCGGCGCCAAGGGCATTGTCGGGCCATG
GGTGCATAAATACCCCCATTTCGCCGTGCCCGAACCGCGCATCGGTTTTCTGCAGGAGGCGCTGCGCTGGTGGGATCACT
GGCTCAAGGATATCGACACCGGAGTGACGCAGGACCCTGACTACCGCGCCTACATCATGGACGGCGCGCGCCCGCAGCGC
TGGTATACCGAACGCCCGGGCCGCTGGGTGGCGGAGGAATATGGCGCGACAACCCATATCCCCCATCGCTCCCTGCATCT
GACGAACAACGGGCTGTCGGATGGGGCCGGTGCCTTGCGGGCAGAGGTCTCATCGCCACAGGATTGCGGTGCGGAATCCG
GTGAATATTGCGCGATCTGGCTGGGGCCGGAAATGCCGGGTGATCAGCGGCGCGATGATACGCATTCCACCACGTTTGAC
AGCGCCCCGGCGGAGGATGACACGGATATCTTCGGCGCGCCGCGCATCACCTTGCGGCTGAGTTCTGACCAGCCACAGAC
GCAGATCGCCGTGCGGCTCAATCACGTGCATCCCGATGGTGCGACGACGCGCATCACATATGGCGTGATGAACCTGAGCC
ACCGCGACGGGCATGCCAACCCCAGCCATCTGACGCCGGGGGAACCGGTCCGTGTGGTTTTCCACCTCGATCATATCGCC
TACCGGCTGCCCAAGGGTCACAAACTGCGGGTGTCCGTGTCGACAAACTACTGGCCGCTGATCTGGCCCGCACCGCAGGC
GGCCCGGATCACGCTGCACAGCGGGACAATGAACCTGCCCGTGCGCCGCACCGCGCGGCGCGACGAATGCCAGTTCGGAC
CGCCGACCGCCGCTGAACCCTGGCAGGTCGAAACCCTGCGCGAGGCCAACAGCCTGCGACGCCGCGAAACGGACATGACC
ACAGGTATCGTATCGCTTGTCATCGAGGATGACTTCGGCAAGCTGCGCGATATTGAACATGGCCTGATCGCGGGTTCGGT
TGCGCGCGAACGCTGGGATATTCACCCGGATGATCCCCTGTCGGCCAGCGGTACCTGCCATTGGACCGAGGAGATCGAAC
GGGACAACATACGCCTGCGTACGGAAACGCACAGCAAAATGTGGTGCGATGCCGACACGTTTTTCCTCTCTGCACGCATC
GAAGCCTATGAGAACGACGAATGCATCTATGCACGTGATGTGTCGGACCAAATTCCGCGCGACCACATTTAG

Upstream 100 bases:

>100_bases
CGACGGGCACAAATGTGATGGACCTCGTCATCGCGCTGAAGGTGTGACAAGGCCACACCGACTGCTTGACAACAGGGCGC
AAGGCGGCAACCGTTAGCGC

Downstream 100 bases:

>100_bases
ATGGGTGCAATGAAATTCACGCAATAAGCCTTGCGGCATGGCAGGAAATGCGCATGCTTACTGACATCAAGAAATAACAG
ATGAGCGCACAAAGCGCGTC

Product: X-Pro dipeptidyl-peptidase family protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MADDTSLRDIEEDADFGITLSDGCRLSARLWKPKDAGSDPVPVILEYLPYRKRDGTCARDALTHPWFAARGYACLRVDIR
GNGDSEGLMQDEYTPQELADAVEVINQIAAKDWCNGRVGMMGISWGGFNSLQVAALDPAPLKAVITLCSTVDRYADDIHY
KGGCLLNENLGWGSTMWAYSSRAPDPALRPDWRAMWLERLENEPFLPAVWLRHQRRDTYWQHGSVCEDYSAIKAKVLAIG
GWGDAYKNAVPQLVEGLPGAKGIVGPWVHKYPHFAVPEPRIGFLQEALRWWDHWLKDIDTGVTQDPDYRAYIMDGARPQR
WYTERPGRWVAEEYGATTHIPHRSLHLTNNGLSDGAGALRAEVSSPQDCGAESGEYCAIWLGPEMPGDQRRDDTHSTTFD
SAPAEDDTDIFGAPRITLRLSSDQPQTQIAVRLNHVHPDGATTRITYGVMNLSHRDGHANPSHLTPGEPVRVVFHLDHIA
YRLPKGHKLRVSVSTNYWPLIWPAPQAARITLHSGTMNLPVRRTARRDECQFGPPTAAEPWQVETLREANSLRRRETDMT
TGIVSLVIEDDFGKLRDIEHGLIAGSVARERWDIHPDDPLSASGTCHWTEEIERDNIRLRTETHSKMWCDADTFFLSARI
EAYENDECIYARDVSDQIPRDHI

Sequences:

>Translated_663_residues
MADDTSLRDIEEDADFGITLSDGCRLSARLWKPKDAGSDPVPVILEYLPYRKRDGTCARDALTHPWFAARGYACLRVDIR
GNGDSEGLMQDEYTPQELADAVEVINQIAAKDWCNGRVGMMGISWGGFNSLQVAALDPAPLKAVITLCSTVDRYADDIHY
KGGCLLNENLGWGSTMWAYSSRAPDPALRPDWRAMWLERLENEPFLPAVWLRHQRRDTYWQHGSVCEDYSAIKAKVLAIG
GWGDAYKNAVPQLVEGLPGAKGIVGPWVHKYPHFAVPEPRIGFLQEALRWWDHWLKDIDTGVTQDPDYRAYIMDGARPQR
WYTERPGRWVAEEYGATTHIPHRSLHLTNNGLSDGAGALRAEVSSPQDCGAESGEYCAIWLGPEMPGDQRRDDTHSTTFD
SAPAEDDTDIFGAPRITLRLSSDQPQTQIAVRLNHVHPDGATTRITYGVMNLSHRDGHANPSHLTPGEPVRVVFHLDHIA
YRLPKGHKLRVSVSTNYWPLIWPAPQAARITLHSGTMNLPVRRTARRDECQFGPPTAAEPWQVETLREANSLRRRETDMT
TGIVSLVIEDDFGKLRDIEHGLIAGSVARERWDIHPDDPLSASGTCHWTEEIERDNIRLRTETHSKMWCDADTFFLSARI
EAYENDECIYARDVSDQIPRDHI
>Mature_662_residues
ADDTSLRDIEEDADFGITLSDGCRLSARLWKPKDAGSDPVPVILEYLPYRKRDGTCARDALTHPWFAARGYACLRVDIRG
NGDSEGLMQDEYTPQELADAVEVINQIAAKDWCNGRVGMMGISWGGFNSLQVAALDPAPLKAVITLCSTVDRYADDIHYK
GGCLLNENLGWGSTMWAYSSRAPDPALRPDWRAMWLERLENEPFLPAVWLRHQRRDTYWQHGSVCEDYSAIKAKVLAIGG
WGDAYKNAVPQLVEGLPGAKGIVGPWVHKYPHFAVPEPRIGFLQEALRWWDHWLKDIDTGVTQDPDYRAYIMDGARPQRW
YTERPGRWVAEEYGATTHIPHRSLHLTNNGLSDGAGALRAEVSSPQDCGAESGEYCAIWLGPEMPGDQRRDDTHSTTFDS
APAEDDTDIFGAPRITLRLSSDQPQTQIAVRLNHVHPDGATTRITYGVMNLSHRDGHANPSHLTPGEPVRVVFHLDHIAY
RLPKGHKLRVSVSTNYWPLIWPAPQAARITLHSGTMNLPVRRTARRDECQFGPPTAAEPWQVETLREANSLRRRETDMTT
GIVSLVIEDDFGKLRDIEHGLIAGSVARERWDIHPDDPLSASGTCHWTEEIERDNIRLRTETHSKMWCDADTFFLSARIE
AYENDECIYARDVSDQIPRDHI

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 74679; Mature: 74548

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDTSLRDIEEDADFGITLSDGCRLSARLWKPKDAGSDPVPVILEYLPYRKRDGTCARD
CCCCCCCHHHHCCCCCCEEECCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHH
ALTHPWFAARGYACLRVDIRGNGDSEGLMQDEYTPQELADAVEVINQIAAKDWCNGRVGM
HHCCCCHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
MGISWGGFNSLQVAALDPAPLKAVITLCSTVDRYADDIHYKGGCLLNENLGWGSTMWAYS
EEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEC
SRAPDPALRPDWRAMWLERLENEPFLPAVWLRHQRRDTYWQHGSVCEDYSAIKAKVLAIG
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCEEEEEEEE
GWGDAYKNAVPQLVEGLPGAKGIVGPWVHKYPHFAVPEPRIGFLQEALRWWDHWLKDIDT
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GVTQDPDYRAYIMDGARPQRWYTERPGRWVAEEYGATTHIPHRSLHLTNNGLSDGAGALR
CCCCCCCCEEEEECCCCCCCHHCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCHHE
AEVSSPQDCGAESGEYCAIWLGPEMPGDQRRDDTHSTTFDSAPAEDDTDIFGAPRITLRL
ECCCCCHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
SSDQPQTQIAVRLNHVHPDGATTRITYGVMNLSHRDGHANPSHLTPGEPVRVVFHLDHIA
CCCCCCEEEEEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEECHHH
YRLPKGHKLRVSVSTNYWPLIWPAPQAARITLHSGTMNLPVRRTARRDECQFGPPTAAEP
HHCCCCCEEEEEEECCEEEEEECCCCCEEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCC
WQVETLREANSLRRRETDMTTGIVSLVIEDDFGKLRDIEHGLIAGSVARERWDIHPDDPL
CHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHCCHHHHCCHHHHHHCCCCCCCCC
SASGTCHWTEEIERDNIRLRTETHSKMWCDADTFFLSARIEAYENDECIYARDVSDQIPR
CCCCCEEEHHHHCCCCEEEEECCCCCEEECCCEEEEEEEEEEECCCCEEEEECCCCCCCC
DHI
CCC
>Mature Secondary Structure 
ADDTSLRDIEEDADFGITLSDGCRLSARLWKPKDAGSDPVPVILEYLPYRKRDGTCARD
CCCCCCHHHHCCCCCCEEECCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHH
ALTHPWFAARGYACLRVDIRGNGDSEGLMQDEYTPQELADAVEVINQIAAKDWCNGRVGM
HHCCCCHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
MGISWGGFNSLQVAALDPAPLKAVITLCSTVDRYADDIHYKGGCLLNENLGWGSTMWAYS
EEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEC
SRAPDPALRPDWRAMWLERLENEPFLPAVWLRHQRRDTYWQHGSVCEDYSAIKAKVLAIG
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCEEEEEEEE
GWGDAYKNAVPQLVEGLPGAKGIVGPWVHKYPHFAVPEPRIGFLQEALRWWDHWLKDIDT
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GVTQDPDYRAYIMDGARPQRWYTERPGRWVAEEYGATTHIPHRSLHLTNNGLSDGAGALR
CCCCCCCCEEEEECCCCCCCHHCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCCHHE
AEVSSPQDCGAESGEYCAIWLGPEMPGDQRRDDTHSTTFDSAPAEDDTDIFGAPRITLRL
ECCCCCHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
SSDQPQTQIAVRLNHVHPDGATTRITYGVMNLSHRDGHANPSHLTPGEPVRVVFHLDHIA
CCCCCCEEEEEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEECHHH
YRLPKGHKLRVSVSTNYWPLIWPAPQAARITLHSGTMNLPVRRTARRDECQFGPPTAAEP
HHCCCCCEEEEEEECCEEEEEECCCCCEEEEEECCCCCCCCHHCCCCCCCCCCCCCCCCC
WQVETLREANSLRRRETDMTTGIVSLVIEDDFGKLRDIEHGLIAGSVARERWDIHPDDPL
CHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHCCHHHHCCHHHHHHCCCCCCCCC
SASGTCHWTEEIERDNIRLRTETHSKMWCDADTFFLSARIEAYENDECIYARDVSDQIPR
CCCCCEEEHHHHCCCCEEEEECCCCCEEECCCEEEEEEEEEEECCCCEEEEECCCCCCCC
DHI
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]