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The map label for this gene is rpiA

Identifier: 110679207

GI number: 110679207

Start: 1830290

End: 1831078

Strand: Direct

Name: rpiA

Synonym: RD1_1918

Alternate gene names: 110679207

Gene position: 1830290-1831078 (Clockwise)

Preceding gene: 110679204

Following gene: 110679208

Centisome position: 44.28

GC content: 57.03

Gene sequence:

>789_bases
ATGTCTTCCGAACTCTCGCCGATCGACAAGGCAAAATTCGTCTGTGCCAAACGGGCCGCACAACTTGTTGAAAGTGGCAT
GCGGGTTGGCTTGGGCACCGGATCAACAGCGGCCTGGCTCGTGCGCTGTCTGGGGCAAAGAGTGCGCAACGAGGGGCTGC
AGATCACGGGGGTTCCCACATCGACACGTACCGCCGAATTGGCCCGTGAGGTTGGAATCGACATCATCACACTGGATGCG
GCCAAGCGGCTGGATCTGACGATTGACGGTGCGGATGAATTTGACGGTGCGTTCAACCTGATCAAAGGCGGTGGCGGGGC
TTTATTGCATGAAAAGGTGGTAGCGGCCTCGTCTGATCGCATGGTCGTGATTGCCGATGTGGGCAAGGAGGTCGAGACGC
TGGGCGCCTTCCCGCTGCCAATCGAAGTCATCCCCTTCGGATTGCAGACGACCCATGCGCTGGTTGATGAAACCCTTGTG
TCGATGGACGTTCTGGGGCGCGACAGCAGCCTGCGCATGGATGGCGACAAACCTTTCGTCACGGATGAAGGCAACCACAT
CATTGATCTGCACCTCAAACGGATTGGCGATGCGCGGCAGCTGGCGCTGACGCTCAATCAGGTGCCGGGTGTGGTTGAGA
ACGGTCTGTTCATTGATATCTGTGACACGGTTGTGCTGGGTTTTGGGGACGGAAAAGTCGAAGTGCGCGACATCAATGAC
GGCACCATTGCCAGCGAACGCATGATTTTTGCAGAAACCGACAATCTGTTCAGCGATCTGAGCGATTGA

Upstream 100 bases:

>100_bases
TCTGGTGGTGCAGAACTATTCGGCAGGCAGGCGAGAATCGCCCTCGCACCTTGGCTGCATCTTTCTTATAAGGCGCGTGA
GTCCACGCAAGGAGCCTGCG

Downstream 100 bases:

>100_bases
TCGGAGCTATGCCTGTCTGACCGGTGTGACGCAGGAACAGGCAAACCTCTTGGCCCCGCTGCGGGTCAGCAGATTAATAC
AGAAAGGCCCTTCCCATGAC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MSSELSPIDKAKFVCAKRAAQLVESGMRVGLGTGSTAAWLVRCLGQRVRNEGLQITGVPTSTRTAELAREVGIDIITLDA
AKRLDLTIDGADEFDGAFNLIKGGGGALLHEKVVAASSDRMVVIADVGKEVETLGAFPLPIEVIPFGLQTTHALVDETLV
SMDVLGRDSSLRMDGDKPFVTDEGNHIIDLHLKRIGDARQLALTLNQVPGVVENGLFIDICDTVVLGFGDGKVEVRDIND
GTIASERMIFAETDNLFSDLSD

Sequences:

>Translated_262_residues
MSSELSPIDKAKFVCAKRAAQLVESGMRVGLGTGSTAAWLVRCLGQRVRNEGLQITGVPTSTRTAELAREVGIDIITLDA
AKRLDLTIDGADEFDGAFNLIKGGGGALLHEKVVAASSDRMVVIADVGKEVETLGAFPLPIEVIPFGLQTTHALVDETLV
SMDVLGRDSSLRMDGDKPFVTDEGNHIIDLHLKRIGDARQLALTLNQVPGVVENGLFIDICDTVVLGFGDGKVEVRDIND
GTIASERMIFAETDNLFSDLSD
>Mature_261_residues
SSELSPIDKAKFVCAKRAAQLVESGMRVGLGTGSTAAWLVRCLGQRVRNEGLQITGVPTSTRTAELAREVGIDIITLDAA
KRLDLTIDGADEFDGAFNLIKGGGGALLHEKVVAASSDRMVVIADVGKEVETLGAFPLPIEVIPFGLQTTHALVDETLVS
MDVLGRDSSLRMDGDKPFVTDEGNHIIDLHLKRIGDARQLALTLNQVPGVVENGLFIDICDTVVLGFGDGKVEVRDINDG
TIASERMIFAETDNLFSDLSD

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=241, Percent_Identity=36.5145228215768, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1789280, Length=225, Percent_Identity=38.6666666666667, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17551758, Length=244, Percent_Identity=39.344262295082, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324669, Length=248, Percent_Identity=31.0483870967742, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI281364072, Length=218, Percent_Identity=35.7798165137615, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_ROSDO (Q168R5)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_682214.1
- ProteinModelPortal:   Q168R5
- SMR:   Q168R5
- STRING:   Q168R5
- GeneID:   4196820
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1918
- NMPDR:   fig|375451.6.peg.1793
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- PhylomeDB:   Q168R5
- ProtClustDB:   PRK00702
- BioCyc:   RDEN375451:RD1_1918-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 27975; Mature: 27844

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSELSPIDKAKFVCAKRAAQLVESGMRVGLGTGSTAAWLVRCLGQRVRNEGLQITGVPT
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCC
STRTAELAREVGIDIITLDAAKRLDLTIDGADEFDGAFNLIKGGGGALLHEKVVAASSDR
CCHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCCC
MVVIADVGKEVETLGAFPLPIEVIPFGLQTTHALVDETLVSMDVLGRDSSLRMDGDKPFV
EEEEECCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEE
TDEGNHIIDLHLKRIGDARQLALTLNQVPGVVENGLFIDICDTVVLGFGDGKVEVRDIND
ECCCCEEEEEEEECCCCHHHEEEEHHHCCCHHHCCEEEEEECEEEEECCCCEEEEEECCC
GTIASERMIFAETDNLFSDLSD
CCCCCCEEEEEECCHHHHHCCC
>Mature Secondary Structure 
SSELSPIDKAKFVCAKRAAQLVESGMRVGLGTGSTAAWLVRCLGQRVRNEGLQITGVPT
CCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEECCC
STRTAELAREVGIDIITLDAAKRLDLTIDGADEFDGAFNLIKGGGGALLHEKVVAASSDR
CCHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHCCCCCC
MVVIADVGKEVETLGAFPLPIEVIPFGLQTTHALVDETLVSMDVLGRDSSLRMDGDKPFV
EEEEECCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEE
TDEGNHIIDLHLKRIGDARQLALTLNQVPGVVENGLFIDICDTVVLGFGDGKVEVRDIND
ECCCCEEEEEEEECCCCHHHEEEEHHHCCCHHHCCEEEEEECEEEEECCCCEEEEEECCC
GTIASERMIFAETDNLFSDLSD
CCCCCCEEEEEECCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA