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The map label for this gene is pepF [H]

Identifier: 110679110

GI number: 110679110

Start: 1738606

End: 1740426

Strand: Reverse

Name: pepF [H]

Synonym: RD1_1815

Alternate gene names: 110679110

Gene position: 1740426-1738606 (Counterclockwise)

Preceding gene: 110679112

Following gene: 110679107

Centisome position: 42.11

GC content: 58.1

Gene sequence:

>1821_bases
ATGTTTCAACTTCCCTTTCCGGTGCGCGATGCAAATGCTTCAGGCGCGGCTGATCCCTTGGGCGATCTGCCCGAGTGGAA
TCTCGACGATCTCTATACCGGCGAGGATGCGCCCGAACTGAAACGCGATCTGGACTGGCTGGAACAGGCCTGCGCCAGCT
TTGCCACGGATTACGAGGGCAATCTGGAAACCCTCGACGCTGCGGGCTTTCTTGAATGCGTGTTGCGCAACGAAAAAATC
AGCCAGATCGCCGGGCGGATCATGTCCTATGCCGGGCTGCGGTATTACCAACTCACCACAGATGCCGGGCGGGCCAAATT
CATGTCCGACCTGCAGGAAAAGATCACCAATTTCACCACGCCGCTGGTATTTTTCACGCTGGAGATCAACCGGCTTGCGG
ATGATCATCTTGACGGGCTTTATGCGCATAATGGCGATCTTGCGCGCTATAAACCCATCTTTGATCGCATCCGCGCAATG
AAACCCTATCAACTCAGTGATGAGTTGGAGAAGTTCCTGCATGATCTCGGCGTGGTGGGCGATGCCTGGGAGCGGTTGTT
TGACGAAACCATCGCCGGGCTGGAATTCGATGTTGACGGTGAGACGCTCAACATAGAGGGCGCACTGAACCTGCTCACGG
ATCCGGACCGCACCAAACGCGAAGCCGCCGCGCGCGAGTTGGCGGATGTCTTCGGCGCGAACGTCAAAACCTTTGCCCGC
GTGCACAACACTCAGGCCAAGGAAAAAGAGATCGCGGATCGCTGGCGCGGCATGGAAAGCCCACAGCAAGGCCGCCATCT
GAGCAATCAGGTCGAACCCGAAGTGGTCGAAGCGCTGCGCAACGCGGTGGTGAAATCCTATCCGAAACTCAGCCACCGCT
ATTACGAGCTCAAGCGCAAATGGCTGGGCCTCGACAAGATGCAGGTCTGGGACCGCAACGCGCCGCTGCCGCTGGAGGAC
AACCGCATCGTCGGCTGGGATCAGGCGCAAGACATGGTGATGGAGGCCTATACCGCCTTTGATCCGCGCATGGGCGAGAT
CGCCGCGCCGTTTTTCAGCAAGGGCTGGATCGACGCAGGCGTGAAGCCCGGCAAGGCACCCGGTGCTTTTGCGCATCCGA
CCGTCACCGATGTGCACCCCTATGTCATGCTGAACTACCTCGGCAAACCACGCGATGTGATGACCCTCGCGCATGAGCTT
GGGCACGGTGTCCATCAGGTTCTGGCCGCCGGACAGGGGGAGATGCTGTCGTCCACACCGCTCACACTGGCGGAGACGGC
CAGCGTGTTTGGCGAAATGCTCACCTTCCGCAAGATGCTGGACGGCGCCAAGGACAACGCGGAACGCAAAGTCCTGCTGG
CGGGCAAGGTCGAGGATATGATCAATACGGTCGTGCGCCAGATCGCCTTTTACGATTTCGAGTGCAAACTGCATGATGCG
CGGCGCGGTGGCGAATTGACCCCCGATGACATCAACGCGTTGTGGATGTCCGTGCAGGCCGAAAGCCTCGGACCGGCGTT
TGAATTCATGGACGGATACGAAACCTTCTGGGCCTATATCCCGCATTTCGTGCATTCGCCGTTCTACGTCTACGCCTATG
CTTTTGGCGACGGGCTCGTGAATGCGCTCTATTCCGTTTACGCGGAAGGCACCGAAGGATTTGAGGAAAAATACTTCGAC
ATGCTGAAAGCAGGTGGCTCAAAGCACCACAAGGAATTGCTGGCGCCATTCGGTCTGGATGCCTCCGACCCTGCGTTCTG
GGACAAGGGGCTGAGCATGATTTCAGGCTTCATCGACGAGTTGGAAGCGATGGAAGAGTAA

Upstream 100 bases:

>100_bases
GCCGCCAAAGCGTTATGTTTGCGCAGATAATGACATCTGCTTGCTTGTACCCTGCCCTGCTGCGGCCTAGGTAATACAGG
AATTCAAAACGAGGTCTTTC

Downstream 100 bases:

>100_bases
TCCGCAAAGACAGGATCGCCCGGCCCTTGCGATCAGGGGCCGGGCGGTTTTGTTTGCGGCGTCTGACCCGTGAGGGGGGA
GTCAGACGCGGGATGGTAGG

Product: oligoendopeptidase F, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MFQLPFPVRDANASGAADPLGDLPEWNLDDLYTGEDAPELKRDLDWLEQACASFATDYEGNLETLDAAGFLECVLRNEKI
SQIAGRIMSYAGLRYYQLTTDAGRAKFMSDLQEKITNFTTPLVFFTLEINRLADDHLDGLYAHNGDLARYKPIFDRIRAM
KPYQLSDELEKFLHDLGVVGDAWERLFDETIAGLEFDVDGETLNIEGALNLLTDPDRTKREAAARELADVFGANVKTFAR
VHNTQAKEKEIADRWRGMESPQQGRHLSNQVEPEVVEALRNAVVKSYPKLSHRYYELKRKWLGLDKMQVWDRNAPLPLED
NRIVGWDQAQDMVMEAYTAFDPRMGEIAAPFFSKGWIDAGVKPGKAPGAFAHPTVTDVHPYVMLNYLGKPRDVMTLAHEL
GHGVHQVLAAGQGEMLSSTPLTLAETASVFGEMLTFRKMLDGAKDNAERKVLLAGKVEDMINTVVRQIAFYDFECKLHDA
RRGGELTPDDINALWMSVQAESLGPAFEFMDGYETFWAYIPHFVHSPFYVYAYAFGDGLVNALYSVYAEGTEGFEEKYFD
MLKAGGSKHHKELLAPFGLDASDPAFWDKGLSMISGFIDELEAMEE

Sequences:

>Translated_606_residues
MFQLPFPVRDANASGAADPLGDLPEWNLDDLYTGEDAPELKRDLDWLEQACASFATDYEGNLETLDAAGFLECVLRNEKI
SQIAGRIMSYAGLRYYQLTTDAGRAKFMSDLQEKITNFTTPLVFFTLEINRLADDHLDGLYAHNGDLARYKPIFDRIRAM
KPYQLSDELEKFLHDLGVVGDAWERLFDETIAGLEFDVDGETLNIEGALNLLTDPDRTKREAAARELADVFGANVKTFAR
VHNTQAKEKEIADRWRGMESPQQGRHLSNQVEPEVVEALRNAVVKSYPKLSHRYYELKRKWLGLDKMQVWDRNAPLPLED
NRIVGWDQAQDMVMEAYTAFDPRMGEIAAPFFSKGWIDAGVKPGKAPGAFAHPTVTDVHPYVMLNYLGKPRDVMTLAHEL
GHGVHQVLAAGQGEMLSSTPLTLAETASVFGEMLTFRKMLDGAKDNAERKVLLAGKVEDMINTVVRQIAFYDFECKLHDA
RRGGELTPDDINALWMSVQAESLGPAFEFMDGYETFWAYIPHFVHSPFYVYAYAFGDGLVNALYSVYAEGTEGFEEKYFD
MLKAGGSKHHKELLAPFGLDASDPAFWDKGLSMISGFIDELEAMEE
>Mature_606_residues
MFQLPFPVRDANASGAADPLGDLPEWNLDDLYTGEDAPELKRDLDWLEQACASFATDYEGNLETLDAAGFLECVLRNEKI
SQIAGRIMSYAGLRYYQLTTDAGRAKFMSDLQEKITNFTTPLVFFTLEINRLADDHLDGLYAHNGDLARYKPIFDRIRAM
KPYQLSDELEKFLHDLGVVGDAWERLFDETIAGLEFDVDGETLNIEGALNLLTDPDRTKREAAARELADVFGANVKTFAR
VHNTQAKEKEIADRWRGMESPQQGRHLSNQVEPEVVEALRNAVVKSYPKLSHRYYELKRKWLGLDKMQVWDRNAPLPLED
NRIVGWDQAQDMVMEAYTAFDPRMGEIAAPFFSKGWIDAGVKPGKAPGAFAHPTVTDVHPYVMLNYLGKPRDVMTLAHEL
GHGVHQVLAAGQGEMLSSTPLTLAETASVFGEMLTFRKMLDGAKDNAERKVLLAGKVEDMINTVVRQIAFYDFECKLHDA
RRGGELTPDDINALWMSVQAESLGPAFEFMDGYETFWAYIPHFVHSPFYVYAYAFGDGLVNALYSVYAEGTEGFEEKYFD
MLKAGGSKHHKELLAPFGLDASDPAFWDKGLSMISGFIDELEAMEE

Specific function: Has oligopeptidase activity and degrades a variety of small bioactive peptides, including bradykinin, neurotensin, and peptide fragments of substance P and adrenocorticotropin. Also hydrolyzes the synthetic collagen-like substrate N-(3-[2- furyl]acryloyl)

COG id: COG1164

COG function: function code E; Oligoendopeptidase F

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567
- InterPro:   IPR004438
- InterPro:   IPR013647 [H]

Pfam domain/function: PF01432 Peptidase_M3; PF08439 Peptidase_M3_N [H]

EC number: NA

Molecular weight: Translated: 68178; Mature: 68178

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQLPFPVRDANASGAADPLGDLPEWNLDDLYTGEDAPELKRDLDWLEQACASFATDYEG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
NLETLDAAGFLECVLRNEKISQIAGRIMSYAGLRYYQLTTDAGRAKFMSDLQEKITNFTT
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHCC
PLVFFTLEINRLADDHLDGLYAHNGDLARYKPIFDRIRAMKPYQLSDELEKFLHDLGVVG
CCEEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHH
DAWERLFDETIAGLEFDVDGETLNIEGALNLLTDPDRTKREAAARELADVFGANVKTFAR
HHHHHHHHHHHCCCEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
VHNTQAKEKEIADRWRGMESPQQGRHLSNQVEPEVVEALRNAVVKSYPKLSHRYYELKRK
HHHCHHHHHHHHHHHCCCCCCHHCCHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
WLGLDKMQVWDRNAPLPLEDNRIVGWDQAQDMVMEAYTAFDPRMGEIAAPFFSKGWIDAG
HCCCCHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCC
VKPGKAPGAFAHPTVTDVHPYVMLNYLGKPRDVMTLAHELGHGVHQVLAAGQGEMLSSTP
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LTLAETASVFGEMLTFRKMLDGAKDNAERKVLLAGKVEDMINTVVRQIAFYDFECKLHDA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEECC
RRGGELTPDDINALWMSVQAESLGPAFEFMDGYETFWAYIPHFVHSPFYVYAYAFGDGLV
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHH
NALYSVYAEGTEGFEEKYFDMLKAGGSKHHKELLAPFGLDASDPAFWDKGLSMISGFIDE
HHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LEAMEE
HHHHCC
>Mature Secondary Structure
MFQLPFPVRDANASGAADPLGDLPEWNLDDLYTGEDAPELKRDLDWLEQACASFATDYEG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
NLETLDAAGFLECVLRNEKISQIAGRIMSYAGLRYYQLTTDAGRAKFMSDLQEKITNFTT
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHCC
PLVFFTLEINRLADDHLDGLYAHNGDLARYKPIFDRIRAMKPYQLSDELEKFLHDLGVVG
CCEEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHH
DAWERLFDETIAGLEFDVDGETLNIEGALNLLTDPDRTKREAAARELADVFGANVKTFAR
HHHHHHHHHHHCCCEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
VHNTQAKEKEIADRWRGMESPQQGRHLSNQVEPEVVEALRNAVVKSYPKLSHRYYELKRK
HHHCHHHHHHHHHHHCCCCCCHHCCHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
WLGLDKMQVWDRNAPLPLEDNRIVGWDQAQDMVMEAYTAFDPRMGEIAAPFFSKGWIDAG
HCCCCHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCC
VKPGKAPGAFAHPTVTDVHPYVMLNYLGKPRDVMTLAHELGHGVHQVLAAGQGEMLSSTP
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LTLAETASVFGEMLTFRKMLDGAKDNAERKVLLAGKVEDMINTVVRQIAFYDFECKLHDA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEECC
RRGGELTPDDINALWMSVQAESLGPAFEFMDGYETFWAYIPHFVHSPFYVYAYAFGDGLV
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHH
NALYSVYAEGTEGFEEKYFDMLKAGGSKHHKELLAPFGLDASDPAFWDKGLSMISGFIDE
HHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LEAMEE
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757883; 12354221 [H]