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The map label for this gene is sucC [H]

Identifier: 110678921

GI number: 110678921

Start: 1557984

End: 1559177

Strand: Reverse

Name: sucC [H]

Synonym: RD1_1615

Alternate gene names: 110678921

Gene position: 1559177-1557984 (Counterclockwise)

Preceding gene: 110678923

Following gene: 110678920

Centisome position: 37.72

GC content: 57.12

Gene sequence:

>1194_bases
ATGAATATCCACGAATACCAAGCCAAAGCCCTCCTCCGCAGCTATGGCGCACCGGTCTCCGACGGGCGGGTCGTGCTCAA
GGCCGAAGACGCCAAGACGGCAGCAGGAGAGCTTGATGGTCCGTTGTGGGTAGTTAAAGCGCAAATTCATGCGGGCGGTC
GCGGCAAGGGATCGTTCAAGGAAGCCGACGCCGGTGAAAAAGGTGGCGTGCGCCTGACCAAATCCGTGGCAGAGGCGGCG
GAAGAAGCCAAGAAAATGCTCGGCCGCACATTGGTGACGCATCAGACAGGCCCCGCAGGCAAACAAGTCAATCGCATCTA
CATCGAAGATGGGTCAGGGATTGAAACCGAACTCTACCTCGCGCTTTTGGTGGACCGCCAAACCAGCCGCGTCAGCTTTG
TCTGCTCAACCGAGGGCGGCATGGACATCGAAGAGGTCGCCGCTTCAACGCCGGAAAAAATCCTGTCTTTCTCCGTGGAT
CCCGCGTCCGGCTATCAGGCGTTTCACGGGCGTCGCATCGCCTTTGCGCTCGGCCTTGAGGGCAAGCAGGTCAAGCAATG
CGTGGGCCTGATGGGCCTGCTTTATACCGCGTTCATGGAAAAAGACATGGAAATGCTGGAAATCAACCCGCTGATCGTCA
CCAATACCGGCGATCTCAAGGTGCTTGATGCCAAGGTGGCTTTTGACGGCAATGCCATCTACCGCCATGCCGACATTTCC
GAACTGCGCGACACGACCGAGGAAGACAGCAAGGAGTTGGAAGCCTCCAAATACGATCTCAACTATATCGCGCTGGATGG
TGAAATCGGCTGCATGGTGAACGGCGCGGGGCTGGCGATGGCGACAATGGACATCATCAAGCTCTATGGCGCGGAACCTG
CGAATTTCCTCGATGTGGGCGGTGGTGCAACCAAGGAAAAGGTCACCGAAGCGTTCAAGATCATCACTTCCGATCCGCAG
GTCAAAGGTATTCTGGTCAACATCTTCGGCGGCATTATGCGCTGCGATGTAATCGCCGAGGGCGTCGTCGCTGCGGTGAA
AGAAGTCGGCCTGAAAGTGCCGCTTGTGGTGCGCCTCGAAGGGACGAACGTGCAACAGGGCAAGGACATCATCAACAACT
CCGGCCTCGATGTCATCGCCGCCGATGACCTCAAGGACGGTGCCCAGAAAATTGTGAAAGCGGTTAAAGGTTGA

Upstream 100 bases:

>100_bases
GAAGAATACTATTCATGTCCGCTTTTTACCGATAATCCGGTTCACTCAGACGAAGATTTCGATCTAGGGTGCGCCAATCG
CAATCTGACAGGACGCTGAC

Downstream 100 bases:

>100_bases
GCCATGGCCCTGCTACTCAAGGTGAAGCCCGATACACTGCGGGAAAACGAGGTGACCGTACCGCGCATGAAATCGGCGGA
CCTGGGATCCGGCGATCTGG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNIHEYQAKALLRSYGAPVSDGRVVLKAEDAKTAAGELDGPLWVVKAQIHAGGRGKGSFKEADAGEKGGVRLTKSVAEAA
EEAKKMLGRTLVTHQTGPAGKQVNRIYIEDGSGIETELYLALLVDRQTSRVSFVCSTEGGMDIEEVAASTPEKILSFSVD
PASGYQAFHGRRIAFALGLEGKQVKQCVGLMGLLYTAFMEKDMEMLEINPLIVTNTGDLKVLDAKVAFDGNAIYRHADIS
ELRDTTEEDSKELEASKYDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKEKVTEAFKIITSDPQ
VKGILVNIFGGIMRCDVIAEGVVAAVKEVGLKVPLVVRLEGTNVQQGKDIINNSGLDVIAADDLKDGAQKIVKAVKG

Sequences:

>Translated_397_residues
MNIHEYQAKALLRSYGAPVSDGRVVLKAEDAKTAAGELDGPLWVVKAQIHAGGRGKGSFKEADAGEKGGVRLTKSVAEAA
EEAKKMLGRTLVTHQTGPAGKQVNRIYIEDGSGIETELYLALLVDRQTSRVSFVCSTEGGMDIEEVAASTPEKILSFSVD
PASGYQAFHGRRIAFALGLEGKQVKQCVGLMGLLYTAFMEKDMEMLEINPLIVTNTGDLKVLDAKVAFDGNAIYRHADIS
ELRDTTEEDSKELEASKYDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKEKVTEAFKIITSDPQ
VKGILVNIFGGIMRCDVIAEGVVAAVKEVGLKVPLVVRLEGTNVQQGKDIINNSGLDVIAADDLKDGAQKIVKAVKG
>Mature_397_residues
MNIHEYQAKALLRSYGAPVSDGRVVLKAEDAKTAAGELDGPLWVVKAQIHAGGRGKGSFKEADAGEKGGVRLTKSVAEAA
EEAKKMLGRTLVTHQTGPAGKQVNRIYIEDGSGIETELYLALLVDRQTSRVSFVCSTEGGMDIEEVAASTPEKILSFSVD
PASGYQAFHGRRIAFALGLEGKQVKQCVGLMGLLYTAFMEKDMEMLEINPLIVTNTGDLKVLDAKVAFDGNAIYRHADIS
ELRDTTEEDSKELEASKYDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKEKVTEAFKIITSDPQ
VKGILVNIFGGIMRCDVIAEGVVAAVKEVGLKVPLVVRLEGTNVQQGKDIINNSGLDVIAADDLKDGAQKIVKAVKG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=45.8015267175573, Blast_Score=344, Evalue=7e-95,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=47.6683937823834, Blast_Score=337, Evalue=1e-92,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=47.2375690607735, Blast_Score=310, Evalue=1e-84,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=52.6448362720403, Blast_Score=406, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=45.3164556962025, Blast_Score=330, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI17567829, Length=392, Percent_Identity=44.3877551020408, Blast_Score=323, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=45.2020202020202, Blast_Score=346, Evalue=5e-96,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=47.979797979798, Blast_Score=357, Evalue=1e-98,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=48.7113402061856, Blast_Score=352, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=48.7113402061856, Blast_Score=352, Evalue=4e-97,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=48.8431876606684, Blast_Score=350, Evalue=1e-96,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=48.8431876606684, Blast_Score=350, Evalue=1e-96,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42296; Mature: 42296

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLRSYGAPVSDGRVVLKAEDAKTAAGELDGPLWVVKAQIHAGGRGKGSFK
CCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCC
EADAGEKGGVRLTKSVAEAAEEAKKMLGRTLVTHQTGPAGKQVNRIYIEDGSGIETELYL
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCCCEEEE
ALLVDRQTSRVSFVCSTEGGMDIEEVAASTPEKILSFSVDPASGYQAFHGRRIAFALGLE
EEEEECCCCEEEEEEECCCCCCHHHHHCCCCHHHHEECCCCCCCCHHHCCCEEEEEECCC
GKQVKQCVGLMGLLYTAFMEKDMEMLEINPLIVTNTGDLKVLDAKVAFDGNAIYRHADIS
CHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCEEEEEEEEEECCCEEEEECCHH
ELRDTTEEDSKELEASKYDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
HHHCCCHHHHHHHHHHHCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGATKEKVTEAFKIITSDPQVKGILVNIFGGIMRCDVIAEGVVAAVKEVGLKVPLVVRLE
CCCCHHHHHHHHHHHCCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GTNVQQGKDIINNSGLDVIAADDLKDGAQKIVKAVKG
CCCCCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKALLRSYGAPVSDGRVVLKAEDAKTAAGELDGPLWVVKAQIHAGGRGKGSFK
CCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCCC
EADAGEKGGVRLTKSVAEAAEEAKKMLGRTLVTHQTGPAGKQVNRIYIEDGSGIETELYL
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCCCEEEE
ALLVDRQTSRVSFVCSTEGGMDIEEVAASTPEKILSFSVDPASGYQAFHGRRIAFALGLE
EEEEECCCCEEEEEEECCCCCCHHHHHCCCCHHHHEECCCCCCCCHHHCCCEEEEEECCC
GKQVKQCVGLMGLLYTAFMEKDMEMLEINPLIVTNTGDLKVLDAKVAFDGNAIYRHADIS
CHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCEEEEEEEEEECCCEEEEECCHH
ELRDTTEEDSKELEASKYDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
HHHCCCHHHHHHHHHHHCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGATKEKVTEAFKIITSDPQVKGILVNIFGGIMRCDVIAEGVVAAVKEVGLKVPLVVRLE
CCCCHHHHHHHHHHHCCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GTNVQQGKDIINNSGLDVIAADDLKDGAQKIVKAVKG
CCCCCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA