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The map label for this gene is sucD [H]

Identifier: 110678917

GI number: 110678917

Start: 1555436

End: 1556323

Strand: Reverse

Name: sucD [H]

Synonym: RD1_1611

Alternate gene names: 110678917

Gene position: 1556323-1555436 (Counterclockwise)

Preceding gene: 110678918

Following gene: 110678916

Centisome position: 37.66

GC content: 61.71

Gene sequence:

>888_bases
ATGGCCGTACTTATCGACGAAAACACCAAGGTGATCTGTCAGGGTCTGACCGGCTCGCAGGGCACCTTTCACTCCGAACA
GGCCATCGCTTACGGGACAAAAATGGTGGGCGGCGTGACCCCCGGCAAGGGCGGACAGACGCATCTGGACCTGCCGGTGT
TCAACTCCGTGCATGAGGCGAAACATGCGACCGAGGCCAACGCCTCCGTGATCTATGTGCCGCCCCCCTTTGCCGCCGAC
AGCATCCTTGAGGCGATTGATGCCGAGATGGAACTCATCGTCTGCATCACCGAAGGCATCCCGGTGCTGGACATGATGAA
GGTGCAGCGCGCGCTTGAGGGGTCCAAATCCCGACTGATTGGCCCGAATTGTCCCGGGGTTATCACGCCGGATGCGTGTA
AAATCGGCATTATGCCGGGACATATCCACAAGCGTGGATCTTGCGGTGTCGTGTCACGCTCCGGCACGCTGACCTATGAG
GCGGTCAAGCAGACCACCGATCTGGGGCTGGGCCAGTCCACCGCCGTCGGCATTGGTGGTGATCCGATCAAGGGCACCGA
GCACATCGACGTTTTGGAAATGTTCCTTGCGGACCCAGAGACCACCAGCATCATCATGATCGGCGAAATTGGCGGCTCCG
CCGAGGAAGACGCGGCACAGTTCCTCGCCGATGAAAAGAAAAAGGGCCGCTGGAAGCCGACTGCCGGATTCATCGCGGGC
CGCACAGCCCCTCCCGGTCGTCGCATGGGCCACGCAGGTGCGATTGTTGCCGGTGGCAAGGGCGGTGCCGAGGATAAGAT
CGACGCCATGCGCGCCGCTGGCATCGTCGTCGCCGACAGCCCCGCAACGCTGGGCGAAGCGGTTCAGGAAGCGATTGCGA
AGGGGTGA

Upstream 100 bases:

>100_bases
GCTGATCCGCGTCACCTATTCCGCCGCTGGCAACAGCGGCGATTGCCTCAATGATGGCACCAGTGCCATCGCCATTCAAA
TGTAAGTCAAAGGAAACAAA

Downstream 100 bases:

>100_bases
ATCGCGATCCGAGCATAAGCGAAGCGAATGCGCCAATGGCGCTTTCGAGCGGCGAACGGGCGGAGCCCCGGCCAGCACTC
AAGCGTTGGACTTGCGCACA

Product: succinyl-CoA synthase, alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MAVLIDENTKVICQGLTGSQGTFHSEQAIAYGTKMVGGVTPGKGGQTHLDLPVFNSVHEAKHATEANASVIYVPPPFAAD
SILEAIDAEMELIVCITEGIPVLDMMKVQRALEGSKSRLIGPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYE
AVKQTTDLGLGQSTAVGIGGDPIKGTEHIDVLEMFLADPETTSIIMIGEIGGSAEEDAAQFLADEKKKGRWKPTAGFIAG
RTAPPGRRMGHAGAIVAGGKGGAEDKIDAMRAAGIVVADSPATLGEAVQEAIAKG

Sequences:

>Translated_295_residues
MAVLIDENTKVICQGLTGSQGTFHSEQAIAYGTKMVGGVTPGKGGQTHLDLPVFNSVHEAKHATEANASVIYVPPPFAAD
SILEAIDAEMELIVCITEGIPVLDMMKVQRALEGSKSRLIGPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYE
AVKQTTDLGLGQSTAVGIGGDPIKGTEHIDVLEMFLADPETTSIIMIGEIGGSAEEDAAQFLADEKKKGRWKPTAGFIAG
RTAPPGRRMGHAGAIVAGGKGGAEDKIDAMRAAGIVVADSPATLGEAVQEAIAKG
>Mature_294_residues
AVLIDENTKVICQGLTGSQGTFHSEQAIAYGTKMVGGVTPGKGGQTHLDLPVFNSVHEAKHATEANASVIYVPPPFAADS
ILEAIDAEMELIVCITEGIPVLDMMKVQRALEGSKSRLIGPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYEA
VKQTTDLGLGQSTAVGIGGDPIKGTEHIDVLEMFLADPETTSIIMIGEIGGSAEEDAAQFLADEKKKGRWKPTAGFIAGR
TAPPGRRMGHAGAIVAGGKGGAEDKIDAMRAAGIVVADSPATLGEAVQEAIAKG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=293, Percent_Identity=66.8941979522184, Blast_Score=340, Evalue=8e-94,
Organism=Homo sapiens, GI38569423, Length=263, Percent_Identity=30.4182509505703, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI38569421, Length=263, Percent_Identity=30.4182509505703, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1786949, Length=292, Percent_Identity=68.4931506849315, Blast_Score=396, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17553126, Length=291, Percent_Identity=63.9175257731959, Blast_Score=350, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17550194, Length=289, Percent_Identity=62.6297577854671, Blast_Score=350, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17557344, Length=266, Percent_Identity=29.3233082706767, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=266, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324716, Length=297, Percent_Identity=52.5252525252525, Blast_Score=287, Evalue=1e-78,
Organism=Drosophila melanogaster, GI21356559, Length=291, Percent_Identity=58.4192439862543, Blast_Score=348, Evalue=3e-96,
Organism=Drosophila melanogaster, GI28574296, Length=291, Percent_Identity=63.9175257731959, Blast_Score=344, Evalue=3e-95,
Organism=Drosophila melanogaster, GI281363477, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281363475, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281363473, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30404; Mature: 30273

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLIDENTKVICQGLTGSQGTFHSEQAIAYGTKMVGGVTPGKGGQTHLDLPVFNSVHEA
CEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
KHATEANASVIYVPPPFAADSILEAIDAEMELIVCITEGIPVLDMMKVQRALEGSKSRLI
HHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYEAVKQTTDLGLGQSTAVGIGG
CCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCEEHHHHHHHHHCCCCCCEEECCCC
DPIKGTEHIDVLEMFLADPETTSIIMIGEIGGSAEEDAAQFLADEKKKGRWKPTAGFIAG
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEC
RTAPPGRRMGHAGAIVAGGKGGAEDKIDAMRAAGIVVADSPATLGEAVQEAIAKG
CCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVLIDENTKVICQGLTGSQGTFHSEQAIAYGTKMVGGVTPGKGGQTHLDLPVFNSVHEA
EEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
KHATEANASVIYVPPPFAADSILEAIDAEMELIVCITEGIPVLDMMKVQRALEGSKSRLI
HHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGVITPDACKIGIMPGHIHKRGSCGVVSRSGTLTYEAVKQTTDLGLGQSTAVGIGG
CCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCEEHHHHHHHHHCCCCCCEEECCCC
DPIKGTEHIDVLEMFLADPETTSIIMIGEIGGSAEEDAAQFLADEKKKGRWKPTAGFIAG
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEC
RTAPPGRRMGHAGAIVAGGKGGAEDKIDAMRAAGIVVADSPATLGEAVQEAIAKG
CCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]