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The map label for this gene is yccK [H]

Identifier: 110678892

GI number: 110678892

Start: 1529274

End: 1530266

Strand: Reverse

Name: yccK [H]

Synonym: RD1_1586

Alternate gene names: 110678892

Gene position: 1530266-1529274 (Counterclockwise)

Preceding gene: 110678893

Following gene: 110678888

Centisome position: 37.02

GC content: 58.91

Gene sequence:

>993_bases
ATGCAAAACCGACAGCTGCGCCAAGACGGAAAAACAGTTTCAGCGATCGGTCTGGGGTGTTGGAGCTTTGCAGGATCCTA
CGGGGCCACCAGTGAGAGCGAAGCGCATGAAACACTGGCCGCAGCGCGCGATCTTGGCGTCGATTTCCTCGACACGGCGA
ATGTCTACGGCATGGGCGTATCGGAAAGCATCATCGGTTCCTACCTGAAAACAACGCAAAACACGTTCACCATTGCGACA
AAAGCGGGTATCTCGCGCGATCCGCAAACCGGGGCGCGCGTGTTCAATAACACGGCGGCGTATCTGCGCGGCGAATTGGA
AAACTCCCTGTCACGGCTGGGTCTTGAGCAGGTCGATCTCTATTACATTCATCGTCGCGATGCCGATGTCCCGATTGAAG
ATGTCATGGAAACGCTGCTGGCGTTCAAGGCGGAGGGCAAGATCGGCGGGATCGGGTTTTCCGAAATCTCGCCCGCGTCG
CTCAGACGGGCCGCCGCCGTTGGGAACGTTGATGCGGTACAAAGCGAATACTCCCTCTGGACCCGCCAGCCGGAGATGGG
CATGATCCAGACCTGCAAGGCGCTAGGGGTCGCCTTTGTGCCGTTTTCGCCGCTTGGGCGCGGTATGCTCACAGCGACGC
CACCTGACCCTGCGACCTTCGAAAAAGGTCATTTCCGTACCGGCACACCGCGTTTTTCAGAGCCGAATTTCAGCCACAAC
ATGACCTTTATATCCAAGTTCCAGAGGCTCGCGCAGACGCTTGATATCTCTCCGGCAACTCTGGCGATTGCGTGGTGCCT
GACGCGCGGCGATCACCTCATCCCGATCCCCGGAACGCGCAGCGCAGCGCATTTGGCCGAGTGCGTTGCCGGGTGCTCGT
TTGAGATGACCCGGGAAATCGAAGACGCCATAGATAACATCCTGCCGATTGGATGGGCTCATGGCGACCGCTACGCGCCG
GAACAATGGCCGGGCGTGGAAGGCTACTGCTGA

Upstream 100 bases:

>100_bases
AAGGTTTAAAAACGGCGCCTCATCGCTTAGTCAGCCTGTGGCGAAGGTGCGTACTTGTGTCTTTGCGCCGCCAAACAGCA
ACCAGATCAAAGGGTCAGAC

Downstream 100 bases:

>100_bases
GCCTCTCAAAGGGGCCGCGTTCCAGCTAGAGCGTCTGACGAAATACCTGACACATCAAGTTTCACGTAACGCGCTGAAAT
CCTTGTTTCCAGCGCGTTAC

Product: aldo-keto reductase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MQNRQLRQDGKTVSAIGLGCWSFAGSYGATSESEAHETLAAARDLGVDFLDTANVYGMGVSESIIGSYLKTTQNTFTIAT
KAGISRDPQTGARVFNNTAAYLRGELENSLSRLGLEQVDLYYIHRRDADVPIEDVMETLLAFKAEGKIGGIGFSEISPAS
LRRAAAVGNVDAVQSEYSLWTRQPEMGMIQTCKALGVAFVPFSPLGRGMLTATPPDPATFEKGHFRTGTPRFSEPNFSHN
MTFISKFQRLAQTLDISPATLAIAWCLTRGDHLIPIPGTRSAAHLAECVAGCSFEMTREIEDAIDNILPIGWAHGDRYAP
EQWPGVEGYC

Sequences:

>Translated_330_residues
MQNRQLRQDGKTVSAIGLGCWSFAGSYGATSESEAHETLAAARDLGVDFLDTANVYGMGVSESIIGSYLKTTQNTFTIAT
KAGISRDPQTGARVFNNTAAYLRGELENSLSRLGLEQVDLYYIHRRDADVPIEDVMETLLAFKAEGKIGGIGFSEISPAS
LRRAAAVGNVDAVQSEYSLWTRQPEMGMIQTCKALGVAFVPFSPLGRGMLTATPPDPATFEKGHFRTGTPRFSEPNFSHN
MTFISKFQRLAQTLDISPATLAIAWCLTRGDHLIPIPGTRSAAHLAECVAGCSFEMTREIEDAIDNILPIGWAHGDRYAP
EQWPGVEGYC
>Mature_330_residues
MQNRQLRQDGKTVSAIGLGCWSFAGSYGATSESEAHETLAAARDLGVDFLDTANVYGMGVSESIIGSYLKTTQNTFTIAT
KAGISRDPQTGARVFNNTAAYLRGELENSLSRLGLEQVDLYYIHRRDADVPIEDVMETLLAFKAEGKIGGIGFSEISPAS
LRRAAAVGNVDAVQSEYSLWTRQPEMGMIQTCKALGVAFVPFSPLGRGMLTATPPDPATFEKGHFRTGTPRFSEPNFSHN
MTFISKFQRLAQTLDISPATLAIAWCLTRGDHLIPIPGTRSAAHLAECVAGCSFEMTREIEDAIDNILPIGWAHGDRYAP
EQWPGVEGYC

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=326, Percent_Identity=25.7668711656442, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=25.6172839506173, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=25.6172839506173, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436969, Length=325, Percent_Identity=25.8461538461538, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4504825, Length=322, Percent_Identity=25.776397515528, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI27436971, Length=324, Percent_Identity=25.6172839506173, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI223718702, Length=171, Percent_Identity=29.2397660818713, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI41327764, Length=171, Percent_Identity=29.8245614035088, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI41152114, Length=175, Percent_Identity=29.7142857142857, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788070, Length=316, Percent_Identity=27.5316455696203, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87081735, Length=314, Percent_Identity=28.9808917197452, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787674, Length=306, Percent_Identity=27.7777777777778, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789375, Length=311, Percent_Identity=28.6173633440514, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789199, Length=341, Percent_Identity=23.4604105571848, Blast_Score=78, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI212645785, Length=161, Percent_Identity=34.1614906832298, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=26.0479041916168, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325384, Length=235, Percent_Identity=28.936170212766, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323998, Length=307, Percent_Identity=25.4071661237785, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319958, Length=299, Percent_Identity=24.4147157190635, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646155, Length=226, Percent_Identity=29.646017699115, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35836; Mature: 35836

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNRQLRQDGKTVSAIGLGCWSFAGSYGATSESEAHETLAAARDLGVDFLDTANVYGMGV
CCCCCCHHCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCEECCCC
SESIIGSYLKTTQNTFTIATKAGISRDPQTGARVFNNTAAYLRGELENSLSRLGLEQVDL
HHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCHHHEEE
YYIHRRDADVPIEDVMETLLAFKAEGKIGGIGFSEISPASLRRAAAVGNVDAVQSEYSLW
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
TRQPEMGMIQTCKALGVAFVPFSPLGRGMLTATPPDPATFEKGHFRTGTPRFSEPNFSHN
HCCCCCCHHHHHHHHCEEECCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MTFISKFQRLAQTLDISPATLAIAWCLTRGDHLIPIPGTRSAAHLAECVAGCSFEMTREI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHH
EDAIDNILPIGWAHGDRYAPEQWPGVEGYC
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQNRQLRQDGKTVSAIGLGCWSFAGSYGATSESEAHETLAAARDLGVDFLDTANVYGMGV
CCCCCCHHCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCEECCCC
SESIIGSYLKTTQNTFTIATKAGISRDPQTGARVFNNTAAYLRGELENSLSRLGLEQVDL
HHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHCCHHHEEE
YYIHRRDADVPIEDVMETLLAFKAEGKIGGIGFSEISPASLRRAAAVGNVDAVQSEYSLW
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
TRQPEMGMIQTCKALGVAFVPFSPLGRGMLTATPPDPATFEKGHFRTGTPRFSEPNFSHN
HCCCCCCHHHHHHHHCEEECCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MTFISKFQRLAQTLDISPATLAIAWCLTRGDHLIPIPGTRSAAHLAECVAGCSFEMTREI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHH
EDAIDNILPIGWAHGDRYAPEQWPGVEGYC
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]