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The map label for this gene is argB

Identifier: 110678768

GI number: 110678768

Start: 1379155

End: 1380018

Strand: Reverse

Name: argB

Synonym: RD1_1452

Alternate gene names: 110678768

Gene position: 1380018-1379155 (Counterclockwise)

Preceding gene: 110678769

Following gene: 110678767

Centisome position: 33.39

GC content: 60.3

Gene sequence:

>864_bases
ATGAAGACCCAAGATATGAACCGCGACTGGATTTCAACCGCAAGCACGCTGAACAAGGCGCTGCCCTATCTGCAACGCTA
TGCCGGGGCGACCGTGGTGATAAAACTTGGCGGTCATTCGATGGGCAGCGATGAGGCGATGGACGAATTTGCCCGTGACG
TGGTGTTGATGCGGCAGGTCGGCGTGAACCCGGTGATTGTGCACGGCGGTGGCCCGATGATCAACGCGATGCTCGACAAG
CTGGACATCAAATCCGAGTTCGTGAACGGCAAGCGGGTGACGGACCGGGCCACCATGGATGTGGTCGAGATGGTGTTGAG
CGGCCTCGTCAACAAGCGGATCGTTCAGGCGATCAACGGTCAGGGCGGCTGCGCGGTGGGTATTTCGGGCAAGGATGCGC
GCCTTATTACCTGTTGTCAGACAGACCCCGATCTGGGCTTTGTGGGCACACCGCAGGATGTTGACCCGCGCCTTTTGCGC
GACCTCACCGAAAAGGAATACATTCCCGTCATTGCGCCCTTGGGGGCGGACCAAACGGGCCAGACCTATAACATCAACGG
GGATACGGCTGCGGGTGCGGTCGCGGCAGCGCTCAAGGCCGACCGGCTGCTTTTGCTGACGGATGTTGCCGGGGTGAAAA
ACGACGCCGGCGATGTGCTCACTGAACTGAGTGCGAAACAGATCGAAGATATGACCCGCGATGGCACAATCGCCGGGGGC
ATGATCCCGAAAACGGAAACAGCGCTTGCCGCATTGCGCGGCGGCGTGCGTGCAGCAGTCATTCTGGATGGGCGCGCCCC
GAACGCCTGCTTGCTGGAACTCTTTACCGAACATGGTGCAGGCTCGATCATCCGCGCGGACTAG

Upstream 100 bases:

>100_bases
TTGTTATCACCTCGAGTGAAAAGGGATGGGGTATCCCCACACTGCGCTCGATCATCACCGACCTGACCTGACACGCCCCA
ACCAAACCCATGGCCCCAAG

Downstream 100 bases:

>100_bases
CGTTCCGCCATGCGATGGCATAGGCGTTTTCTGACGCAGATGTGTCAGGGAACGGCTTGTTCTGACAGTACTGGCGACTA
GGTTAGACACATGGAAAACG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKTQDMNRDWISTASTLNKALPYLQRYAGATVVIKLGGHSMGSDEAMDEFARDVVLMRQVGVNPVIVHGGGPMINAMLDK
LDIKSEFVNGKRVTDRATMDVVEMVLSGLVNKRIVQAINGQGGCAVGISGKDARLITCCQTDPDLGFVGTPQDVDPRLLR
DLTEKEYIPVIAPLGADQTGQTYNINGDTAAGAVAAALKADRLLLLTDVAGVKNDAGDVLTELSAKQIEDMTRDGTIAGG
MIPKTETALAALRGGVRAAVILDGRAPNACLLELFTEHGAGSIIRAD

Sequences:

>Translated_287_residues
MKTQDMNRDWISTASTLNKALPYLQRYAGATVVIKLGGHSMGSDEAMDEFARDVVLMRQVGVNPVIVHGGGPMINAMLDK
LDIKSEFVNGKRVTDRATMDVVEMVLSGLVNKRIVQAINGQGGCAVGISGKDARLITCCQTDPDLGFVGTPQDVDPRLLR
DLTEKEYIPVIAPLGADQTGQTYNINGDTAAGAVAAALKADRLLLLTDVAGVKNDAGDVLTELSAKQIEDMTRDGTIAGG
MIPKTETALAALRGGVRAAVILDGRAPNACLLELFTEHGAGSIIRAD
>Mature_287_residues
MKTQDMNRDWISTASTLNKALPYLQRYAGATVVIKLGGHSMGSDEAMDEFARDVVLMRQVGVNPVIVHGGGPMINAMLDK
LDIKSEFVNGKRVTDRATMDVVEMVLSGLVNKRIVQAINGQGGCAVGISGKDARLITCCQTDPDLGFVGTPQDVDPRLLR
DLTEKEYIPVIAPLGADQTGQTYNINGDTAAGAVAAALKADRLLLLTDVAGVKNDAGDVLTELSAKQIEDMTRDGTIAGG
MIPKTETALAALRGGVRAAVILDGRAPNACLLELFTEHGAGSIIRAD

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=223, Percent_Identity=36.322869955157, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789181, Length=279, Percent_Identity=24.7311827956989, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=288, Percent_Identity=26.7361111111111, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_ROSDO (Q16AA4)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_681775.1
- ProteinModelPortal:   Q16AA4
- SMR:   Q16AA4
- STRING:   Q16AA4
- GeneID:   4197265
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1452
- NMPDR:   fig|375451.6.peg.1361
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q16AA4
- ProtClustDB:   PRK00942
- BioCyc:   RDEN375451:RD1_1452-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 30287; Mature: 30287

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: BINDING 92-92 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQDMNRDWISTASTLNKALPYLQRYAGATVVIKLGGHSMGSDEAMDEFARDVVLMRQV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHC
GVNPVIVHGGGPMINAMLDKLDIKSEFVNGKRVTDRATMDVVEMVLSGLVNKRIVQAING
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QGGCAVGISGKDARLITCCQTDPDLGFVGTPQDVDPRLLRDLTEKEYIPVIAPLGADQTG
CCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCC
QTYNINGDTAAGAVAAALKADRLLLLTDVAGVKNDAGDVLTELSAKQIEDMTRDGTIAGG
CEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEECC
MIPKTETALAALRGGVRAAVILDGRAPNACLLELFTEHGAGSIIRAD
CCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MKTQDMNRDWISTASTLNKALPYLQRYAGATVVIKLGGHSMGSDEAMDEFARDVVLMRQV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHC
GVNPVIVHGGGPMINAMLDKLDIKSEFVNGKRVTDRATMDVVEMVLSGLVNKRIVQAING
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QGGCAVGISGKDARLITCCQTDPDLGFVGTPQDVDPRLLRDLTEKEYIPVIAPLGADQTG
CCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCC
QTYNINGDTAAGAVAAALKADRLLLLTDVAGVKNDAGDVLTELSAKQIEDMTRDGTIAGG
CEEECCCCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEECC
MIPKTETALAALRGGVRAAVILDGRAPNACLLELFTEHGAGSIIRAD
CCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA