Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 110678684

GI number: 110678684

Start: 1312077

End: 1312481

Strand: Direct

Name: acpS

Synonym: RD1_1364

Alternate gene names: 110678684

Gene position: 1312077-1312481 (Clockwise)

Preceding gene: 110678683

Following gene: 110678685

Centisome position: 31.75

GC content: 60.0

Gene sequence:

>405_bases
ATGATCCTTGGCATCGGCACGGATCTTGCGAATATTGAGCGTATCGCGCGCACGCTGGACCGCTTTGGGGACAGGTTTCG
CAACCGGGTTTTCACCGATATTGAACAGGTCAAGGCGGAGCGGCGCAAGGATGTTGCTGGCACCTATGCAAAACGCTGGG
CGGCAAAAGAGGCGTGTTCCAAGGCGCTTGGCACTGGCCTTGCCATGGGGATCGCGTGGAAGGACATGTCGGTCACCAAC
CTCAAATCCGGCCAGCCCGTCATGCATGTCACCGGATGGGCCCAAGAGCGGTTGGCGGCGATGACCCCGCCCGGTCATGA
AGCGGTGATCCACGTCACACTGACCGATGATCACCCATGGGCGCAGGCCTTTGTGGTGATCGAGGCCTTGCCCCTCAAAA
GCTGA

Upstream 100 bases:

>100_bases
CCATTGCGCGGGCGTACACGCGTGCCAAGCGCGGTTTTGAGGCGGCGTTTGGTTTCCTGTTTGCATTTGCCAGTTTCAAG
ATCCTGACGACACGGCTGGC

Downstream 100 bases:

>100_bases
CGGATGCCAGGTGCGGCCCAAAACAAAACCACCGGCGCCGTTTGACCGCCGATCGCTGTGTCCTTTGGCATTTCGGCGCG
CAGCGCGTTCACACACGAGC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MILGIGTDLANIERIARTLDRFGDRFRNRVFTDIEQVKAERRKDVAGTYAKRWAAKEACSKALGTGLAMGIAWKDMSVTN
LKSGQPVMHVTGWAQERLAAMTPPGHEAVIHVTLTDDHPWAQAFVVIEALPLKS

Sequences:

>Translated_134_residues
MILGIGTDLANIERIARTLDRFGDRFRNRVFTDIEQVKAERRKDVAGTYAKRWAAKEACSKALGTGLAMGIAWKDMSVTN
LKSGQPVMHVTGWAQERLAAMTPPGHEAVIHVTLTDDHPWAQAFVVIEALPLKS
>Mature_134_residues
MILGIGTDLANIERIARTLDRFGDRFRNRVFTDIEQVKAERRKDVAGTYAKRWAAKEACSKALGTGLAMGIAWKDMSVTN
LKSGQPVMHVTGWAQERLAAMTPPGHEAVIHVTLTDDHPWAQAFVVIEALPLKS

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=131, Percent_Identity=38.1679389312977, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_ROSDO (Q16AI8)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_681691.1
- ProteinModelPortal:   Q16AI8
- SMR:   Q16AI8
- STRING:   Q16AI8
- GeneID:   4197337
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1364
- NMPDR:   fig|375451.6.peg.1277
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q16AI8
- ProtClustDB:   PRK00070
- BioCyc:   RDEN375451:RD1_1364-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14812; Mature: 14812

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGIGTDLANIERIARTLDRFGDRFRNRVFTDIEQVKAERRKDVAGTYAKRWAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLAMGIAWKDMSVTNLKSGQPVMHVTGWAQERLAAMTPPGHEAVIHVTLTDDHPW
HHHHCHHHHHEEECCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCEEEEEEECCCCCH
AQAFVVIEALPLKS
HHHHHHHHCCCCCC
>Mature Secondary Structure
MILGIGTDLANIERIARTLDRFGDRFRNRVFTDIEQVKAERRKDVAGTYAKRWAAKEACS
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLAMGIAWKDMSVTNLKSGQPVMHVTGWAQERLAAMTPPGHEAVIHVTLTDDHPW
HHHHCHHHHHEEECCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCCCEEEEEEECCCCCH
AQAFVVIEALPLKS
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA