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The map label for this gene is lepB [H]

Identifier: 110678685

GI number: 110678685

Start: 1312523

End: 1313515

Strand: Direct

Name: lepB [H]

Synonym: RD1_1365

Alternate gene names: 110678685

Gene position: 1312523-1313515 (Clockwise)

Preceding gene: 110678684

Following gene: 110678686

Centisome position: 31.76

GC content: 60.12

Gene sequence:

>993_bases
TTGACCGCCGATCGCTGTGTCCTTTGGCATTTCGGCGCGCAGCGCGTTCACACACGAGCGGCAAACTCACTGAACCTTGT
GTGGGCCTGTCTTGACAGTGCCCCGCGCCCCCCCCATTACGAGCGAAACAAATTGATGGAGCCTGCCCACATGGCCGCCA
AAGAAGAGAAGACATCCGGAAACGCGATTGTCGAGACGATCAAGACGATCGTCTATGCCCTGCTGATTGCGGGTGTTTTC
CGCACACTGTTCTTTCAGCCCTTCTGGATTCCGTCGGGCTCGATGAAGGAAACGTTGCTGGTGGGCGATTTTCTCTTTGT
GAACAAGATGGCCTATGGCTATTCCTATGCCTCCTGTCCCAGCATCATCATGCCGCGCTTTGGCATCAACATCGACGCCA
AGAACATCTGCGGGTTTCTGGACGGGGACAACACGCGCATTCTGGGGGGAGAGCCCGAGCGCGGCGATGTGATCGTTTTC
CGCCATCCGGTGTCGGGGCGCGATTATATCAAACGTCTGATCGGCTTGCCCGGTGACACCGTGCAGATGCGCGACAGCAT
CGTCTATATCAACGGTGTAGAAGCCCCGCAGGAACCCGCCGGGAACTTTGTCGAGGTGATGGAGCCGCAGGGGCCGGAAG
GGCGCAGGCCGCGCTGTTCAAATGGCCCGGTCGGTGACGGGGGCGACTGCCTCAAGGCGCGCGCGATCGAGACCCTGCCG
AACGGGGTCAGCCACACGGTGCTGGACATCGGGCCACAGGCGTCTGACCGCACGGGTGTCTATACGGTGCCCGCAGGGCA
TTATTTCTTCATCGGGGACAACCGCGACAATTCCGCCGACAGCCGTCTGGCGCGGCAGGTGCGTGGCGTCGGGTTTGTGC
CTTACGAAAATCTGATCGGGCGGGCAGACCGGGTGATGTTCTCCTCCGCGGGACGGTCCATGTTGTTTTTCTGGACATGG
CGCGGTGATCGTTTCTTCAAGAGGGTGGAGTGA

Upstream 100 bases:

>100_bases
ATGATCACCCATGGGCGCAGGCCTTTGTGGTGATCGAGGCCTTGCCCCTCAAAAGCTGACGGATGCCAGGTGCGGCCCAA
AACAAAACCACCGGCGCCGT

Downstream 100 bases:

>100_bases
AACTCTCGGCGGAACTGAAGTCCTTTCAAAAGCGGCTCGGGCATCAGTTTAACCAACCGGCGCTTTTGGCTCAGGCGGTA
ACGCATGCCTCCATGTCCAC

Product: signal peptidase I, putative

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTADRCVLWHFGAQRVHTRAANSLNLVWACLDSAPRPPHYERNKLMEPAHMAAKEEKTSGNAIVETIKTIVYALLIAGVF
RTLFFQPFWIPSGSMKETLLVGDFLFVNKMAYGYSYASCPSIIMPRFGINIDAKNICGFLDGDNTRILGGEPERGDVIVF
RHPVSGRDYIKRLIGLPGDTVQMRDSIVYINGVEAPQEPAGNFVEVMEPQGPEGRRPRCSNGPVGDGGDCLKARAIETLP
NGVSHTVLDIGPQASDRTGVYTVPAGHYFFIGDNRDNSADSRLARQVRGVGFVPYENLIGRADRVMFSSAGRSMLFFWTW
RGDRFFKRVE

Sequences:

>Translated_330_residues
MTADRCVLWHFGAQRVHTRAANSLNLVWACLDSAPRPPHYERNKLMEPAHMAAKEEKTSGNAIVETIKTIVYALLIAGVF
RTLFFQPFWIPSGSMKETLLVGDFLFVNKMAYGYSYASCPSIIMPRFGINIDAKNICGFLDGDNTRILGGEPERGDVIVF
RHPVSGRDYIKRLIGLPGDTVQMRDSIVYINGVEAPQEPAGNFVEVMEPQGPEGRRPRCSNGPVGDGGDCLKARAIETLP
NGVSHTVLDIGPQASDRTGVYTVPAGHYFFIGDNRDNSADSRLARQVRGVGFVPYENLIGRADRVMFSSAGRSMLFFWTW
RGDRFFKRVE
>Mature_329_residues
TADRCVLWHFGAQRVHTRAANSLNLVWACLDSAPRPPHYERNKLMEPAHMAAKEEKTSGNAIVETIKTIVYALLIAGVFR
TLFFQPFWIPSGSMKETLLVGDFLFVNKMAYGYSYASCPSIIMPRFGINIDAKNICGFLDGDNTRILGGEPERGDVIVFR
HPVSGRDYIKRLIGLPGDTVQMRDSIVYINGVEAPQEPAGNFVEVMEPQGPEGRRPRCSNGPVGDGGDCLKARAIETLPN
GVSHTVLDIGPQASDRTGVYTVPAGHYFFIGDNRDNSADSRLARQVRGVGFVPYENLIGRADRVMFSSAGRSMLFFWTWR
GDRFFKRVE

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=276, Percent_Identity=34.4202898550725, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 36683; Mature: 36552

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADRCVLWHFGAQRVHTRAANSLNLVWACLDSAPRPPHYERNKLMEPAHMAAKEEKTSG
CCCCEEEEEECCCHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHCCCC
NAIVETIKTIVYALLIAGVFRTLFFQPFWIPSGSMKETLLVGDFLFVNKMAYGYSYASCP
HHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEHHHHHHHHHHHCCCHHCCC
SIIMPRFGINIDAKNICGFLDGDNTRILGGEPERGDVIVFRHPVSGRDYIKRLIGLPGDT
HHHHHCCCCCCCHHHHEEEECCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHCCCCCC
VQMRDSIVYINGVEAPQEPAGNFVEVMEPQGPEGRRPRCSNGPVGDGGDCLKARAIETLP
EEECCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
NGVSHTVLDIGPQASDRTGVYTVPAGHYFFIGDNRDNSADSRLARQVRGVGFVPYENLIG
CCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHC
RADRVMFSSAGRSMLFFWTWRGDRFFKRVE
HHHHHHHHCCCCEEEEEEEECCCHHHHCCC
>Mature Secondary Structure 
TADRCVLWHFGAQRVHTRAANSLNLVWACLDSAPRPPHYERNKLMEPAHMAAKEEKTSG
CCCEEEEEECCCHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHCCCC
NAIVETIKTIVYALLIAGVFRTLFFQPFWIPSGSMKETLLVGDFLFVNKMAYGYSYASCP
HHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCEEEHHHHHHHHHHHCCCHHCCC
SIIMPRFGINIDAKNICGFLDGDNTRILGGEPERGDVIVFRHPVSGRDYIKRLIGLPGDT
HHHHHCCCCCCCHHHHEEEECCCCEEEECCCCCCCCEEEEECCCCCHHHHHHHHCCCCCC
VQMRDSIVYINGVEAPQEPAGNFVEVMEPQGPEGRRPRCSNGPVGDGGDCLKARAIETLP
EEECCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
NGVSHTVLDIGPQASDRTGVYTVPAGHYFFIGDNRDNSADSRLARQVRGVGFVPYENLIG
CCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHC
RADRVMFSSAGRSMLFFWTWRGDRFFKRVE
HHHHHHHHCCCCEEEEEEEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]