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The map label for this gene is rdxI [H]

Identifier: 110678601

GI number: 110678601

Start: 1238116

End: 1240305

Strand: Direct

Name: rdxI [H]

Synonym: RD1_1276

Alternate gene names: 110678601

Gene position: 1238116-1240305 (Clockwise)

Preceding gene: 110678600

Following gene: 110678602

Centisome position: 29.96

GC content: 62.51

Gene sequence:

>2190_bases
ATGACGGCAACGGCCACAAATGGCCCTGCGAGCTGCCCCGGTTGTCTTTCGGCACCTGCCGCGCGCGCTGAAGTGCCGTT
GCCGGATGCGCAGCTGGCCCTGTCCTTGCCGACAATCCATTGCCAGGCTTGTATTTCAAAGGTTGAAAACAGCCTGACGG
CCCATGCTGGTGTGCGTGCGGCGCGCGTCAACCTGACACGCAAACGCGTGATGATTGATGCCGCTCCGGGTGTGACGGCG
CAGGAGCTTGCCGATCTGGTCATGGCCGCGGGTTTTGAAGCGCATGAGCTTGATCTGGGCGCGCTCTCGCAGACGCAGAC
CGATGCCGCCAGTCGTGATATCCTCATGCGCCTTGCGGTTGCCGGCTTTGCCGCCATGAATGTGATGTTGTTATCGGTCG
CGGTCTGGTCGGGGGCCACGGATGCAACGCGGGACATGTTCCATTGGATATCTGCAGCGATCACCCTGCCGGCCCTTGCC
TTTTCCGCCCAGCCGTTTTTCCGGAACGCATGGGCGGCGCTGCGGGCGGGGCGGCTCAATATGGATGTGCCGATCACATT
GGCCATTGTGCTGGCGGTCGTAACATCCCTTTGGGAAACCGGGCTTTCCGGCAAGCACGCCTATTTTGACGCCGCGCTGA
CGCTGGTCTTCTTTTTGCTGGCGGGTCGCTGGTTGGACTCGCGTGCGCGCTCTGCCGCACGCTCTGCCGCCGAAGAACTG
ACCGCGCTCGAAGTGCCCCGGGCCTTCCGAATTCAAAACGGTGAAACCAGCGAAATTGCCGTGAGCGCGCTGCGTCTCGG
GGATCATGTGCTGGTGCGCCCCGGTGCGCGCGCGCCCGTGGATGGCGTTGTGATTGACGGCACATCCGAGGTCGACCGCT
CTGCCCTGACCGGTGAGGCAATGCCGGTCATGCGCACGGTCGGTGACCCGATGAGCACAGGCGAGGTGAACCTGACAGGG
CCATTGACACTTGAGGCCACAGCGGTGGGCACGGACACATCCCTGCACCAACTCGCCGCCCTTGTCGCCGTCGCCGAAAG
CGGGCGGTCCCGCTACACATCACTGGCGGATCGCGCCGCCAAGCTTTATGCGCCGGGGGTTCATATCCTGTCCGCCCTCG
CATTTCTGGGCTGGCTCTTGTGGTCGGGCGACATGCGTGTGTCACTGAATATTGCGGCAGCGGTACTGATTATCACCTGC
CCCTGCGCGCTCGGTCTTGCGGTGCCGGCAGTTACAACTGCGGCATCCGGGCGGCTGTTTCGAAAGGGTCTCCTGATCAA
GAATGCCACCGCTCTCGAACGTCTGGCAGAGGTGGATACGGTCGTCTTTGACAAAACCGGCACGGTGACGCTGGGCATGC
CGCGCGCCACGAATTGGCATGATCTGACGCAGGATCAACAATCGCTGGCCTATGCGCTGGCGCGGGGATCATCACACCCT
CTGGCGCAGGCAATCGTGACCGCTGCGCAGGATGATGATACGGCTGAGATCGCGCTTTCAAATCTGACGGAGCAACCGGG
ATTTGGCACGCAAGCGCATTATGCGGACAGGCCTGTTCGTCTGGGACGTCCTGAGTGGATCGGGGCGCTGGTTGAAACCG
ATGGTTTGTGCACGGCATTGGATACCGGCGAGGGCGCGCCGATCATCCTGCGGTTCGAAGACCGTCCCCGCCCCGGTGCC
GCTGATCTGATGGCTGCGCTGAAACGGCAGGGAATGCGGGTAATCTTGCTGTCTGGCGATCGTCAGGCACCTGTTGCCCA
AACGGCGGCACATCTGGGAATGCCGGATTTTGCAGCCGAAATGCTGCCCGCTGACAAGGTTGCATTCGTCCAGCGCCTGA
CCGATGAGGGCCAACGGGTCTTGATGATCGGCGATGGTTTGAATGATACCGGCGCTTTGGCGGCGGCACATGTGTCAATC
AGTCCGGCGCAGGCTCTGGATGCAGCACGCGCTGCCTCTGATATCGTGCTGCTCGGTCAGGATCTGATGCCCGTGGCCGA
TGCGGTTGCAACGGCGCGGCTGGCAACCAAGCGCATCCGGGAGAACTTTCAAATCGCAACGGTGTACAACATCGTCGCGG
TGCCGCTTGCTGTCGCCGGTCTGGCCACGCCGCTGATCGCGGCCTTGGCGATGTCGACGTCGTCGCTAACGGTATCGGTC
AATGCTCTGCGGATCAGGGGGCGCGGATGA

Upstream 100 bases:

>100_bases
ATCTGGCGCCGGGAAACTGGAACATCCGCATGTCGGCCACATCCGCTGACGGCCGGGTATTTCGCCAGCGCGTGATCCTG
CATGTTCCAAAGGCGCGTTC

Downstream 100 bases:

>100_bases
ACGTCCTGGCATATCTGATCCCCATTTCCCTGATACTCGGAGGCCTTGGGCTGGCCGGGTTCTTATATACGTTGCGCAGC
CGTCAATACGAAGACCCCGA

Product: RdxI protein

Products: ADP; Orthophosphate. [C]

Alternate protein names: E1-E2 type cation ATPase FixI [H]

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MTATATNGPASCPGCLSAPAARAEVPLPDAQLALSLPTIHCQACISKVENSLTAHAGVRAARVNLTRKRVMIDAAPGVTA
QELADLVMAAGFEAHELDLGALSQTQTDAASRDILMRLAVAGFAAMNVMLLSVAVWSGATDATRDMFHWISAAITLPALA
FSAQPFFRNAWAALRAGRLNMDVPITLAIVLAVVTSLWETGLSGKHAYFDAALTLVFFLLAGRWLDSRARSAARSAAEEL
TALEVPRAFRIQNGETSEIAVSALRLGDHVLVRPGARAPVDGVVIDGTSEVDRSALTGEAMPVMRTVGDPMSTGEVNLTG
PLTLEATAVGTDTSLHQLAALVAVAESGRSRYTSLADRAAKLYAPGVHILSALAFLGWLLWSGDMRVSLNIAAAVLIITC
PCALGLAVPAVTTAASGRLFRKGLLIKNATALERLAEVDTVVFDKTGTVTLGMPRATNWHDLTQDQQSLAYALARGSSHP
LAQAIVTAAQDDDTAEIALSNLTEQPGFGTQAHYADRPVRLGRPEWIGALVETDGLCTALDTGEGAPIILRFEDRPRPGA
ADLMAALKRQGMRVILLSGDRQAPVAQTAAHLGMPDFAAEMLPADKVAFVQRLTDEGQRVLMIGDGLNDTGALAAAHVSI
SPAQALDAARAASDIVLLGQDLMPVADAVATARLATKRIRENFQIATVYNIVAVPLAVAGLATPLIAALAMSTSSLTVSV
NALRIRGRG

Sequences:

>Translated_729_residues
MTATATNGPASCPGCLSAPAARAEVPLPDAQLALSLPTIHCQACISKVENSLTAHAGVRAARVNLTRKRVMIDAAPGVTA
QELADLVMAAGFEAHELDLGALSQTQTDAASRDILMRLAVAGFAAMNVMLLSVAVWSGATDATRDMFHWISAAITLPALA
FSAQPFFRNAWAALRAGRLNMDVPITLAIVLAVVTSLWETGLSGKHAYFDAALTLVFFLLAGRWLDSRARSAARSAAEEL
TALEVPRAFRIQNGETSEIAVSALRLGDHVLVRPGARAPVDGVVIDGTSEVDRSALTGEAMPVMRTVGDPMSTGEVNLTG
PLTLEATAVGTDTSLHQLAALVAVAESGRSRYTSLADRAAKLYAPGVHILSALAFLGWLLWSGDMRVSLNIAAAVLIITC
PCALGLAVPAVTTAASGRLFRKGLLIKNATALERLAEVDTVVFDKTGTVTLGMPRATNWHDLTQDQQSLAYALARGSSHP
LAQAIVTAAQDDDTAEIALSNLTEQPGFGTQAHYADRPVRLGRPEWIGALVETDGLCTALDTGEGAPIILRFEDRPRPGA
ADLMAALKRQGMRVILLSGDRQAPVAQTAAHLGMPDFAAEMLPADKVAFVQRLTDEGQRVLMIGDGLNDTGALAAAHVSI
SPAQALDAARAASDIVLLGQDLMPVADAVATARLATKRIRENFQIATVYNIVAVPLAVAGLATPLIAALAMSTSSLTVSV
NALRIRGRG
>Mature_728_residues
TATATNGPASCPGCLSAPAARAEVPLPDAQLALSLPTIHCQACISKVENSLTAHAGVRAARVNLTRKRVMIDAAPGVTAQ
ELADLVMAAGFEAHELDLGALSQTQTDAASRDILMRLAVAGFAAMNVMLLSVAVWSGATDATRDMFHWISAAITLPALAF
SAQPFFRNAWAALRAGRLNMDVPITLAIVLAVVTSLWETGLSGKHAYFDAALTLVFFLLAGRWLDSRARSAARSAAEELT
ALEVPRAFRIQNGETSEIAVSALRLGDHVLVRPGARAPVDGVVIDGTSEVDRSALTGEAMPVMRTVGDPMSTGEVNLTGP
LTLEATAVGTDTSLHQLAALVAVAESGRSRYTSLADRAAKLYAPGVHILSALAFLGWLLWSGDMRVSLNIAAAVLIITCP
CALGLAVPAVTTAASGRLFRKGLLIKNATALERLAEVDTVVFDKTGTVTLGMPRATNWHDLTQDQQSLAYALARGSSHPL
AQAIVTAAQDDDTAEIALSNLTEQPGFGTQAHYADRPVRLGRPEWIGALVETDGLCTALDTGEGAPIILRFEDRPRPGAA
DLMAALKRQGMRVILLSGDRQAPVAQTAAHLGMPDFAAEMLPADKVAFVQRLTDEGQRVLMIGDGLNDTGALAAAHVSIS
PAQALDAARAASDIVLLGQDLMPVADAVATARLATKRIRENFQIATVYNIVAVPLAVAGLATPLIAALAMSTSSLTVSVN
ALRIRGRG

Specific function: FixI is a pump of a specific cation involved in symbiotic nitrogen fixation. The four proteins FixG, FixH, FixI, and FixS may participate in a membrane-bound complex coupling the FixI cation pump with a redox process catalyzed by FixG [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=793, Percent_Identity=27.3644388398487, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI115529486, Length=825, Percent_Identity=27.6363636363636, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI55743073, Length=542, Percent_Identity=28.9667896678967, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI153946397, Length=257, Percent_Identity=28.7937743190661, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI237681111, Length=255, Percent_Identity=29.8039215686275, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI237681109, Length=255, Percent_Identity=29.8039215686275, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21361181, Length=255, Percent_Identity=29.8039215686275, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI22748667, Length=303, Percent_Identity=25.7425742574257, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4502271, Length=234, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1786691, Length=747, Percent_Identity=30.5220883534137, Blast_Score=271, Evalue=9e-74,
Organism=Escherichia coli, GI1789879, Length=754, Percent_Identity=28.7798408488064, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1786914, Length=460, Percent_Identity=28.695652173913, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17556548, Length=487, Percent_Identity=27.7207392197125, Blast_Score=168, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6320475, Length=640, Percent_Identity=26.5625, Blast_Score=220, Evalue=5e-58,
Organism=Saccharomyces cerevisiae, GI6319772, Length=601, Percent_Identity=27.7870216306156, Blast_Score=210, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6321430, Length=227, Percent_Identity=27.7533039647577, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325221, Length=226, Percent_Identity=26.5486725663717, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI221329854, Length=549, Percent_Identity=29.3260473588342, Blast_Score=190, Evalue=4e-48,
Organism=Drosophila melanogaster, GI281366676, Length=227, Percent_Identity=29.0748898678414, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24648576, Length=247, Percent_Identity=28.3400809716599, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45553437, Length=247, Percent_Identity=28.3400809716599, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45553435, Length=247, Percent_Identity=28.3400809716599, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45553439, Length=247, Percent_Identity=28.3400809716599, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45553441, Length=247, Percent_Identity=28.3400809716599, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24648580, Length=247, Percent_Identity=28.3400809716599, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24648578, Length=247, Percent_Identity=28.3400809716599, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281362164, Length=247, Percent_Identity=28.3400809716599, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24648582, Length=247, Percent_Identity=28.3400809716599, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR000695
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR000150 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 76289; Mature: 76157

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATATNGPASCPGCLSAPAARAEVPLPDAQLALSLPTIHCQACISKVENSLTAHAGVRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCH
ARVNLTRKRVMIDAAPGVTAQELADLVMAAGFEAHELDLGALSQTQTDAASRDILMRLAV
HEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHH
AGFAAMNVMLLSVAVWSGATDATRDMFHWISAAITLPALAFSAQPFFRNAWAALRAGRLN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
MDVPITLAIVLAVVTSLWETGLSGKHAYFDAALTLVFFLLAGRWLDSRARSAARSAAEEL
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
TALEVPRAFRIQNGETSEIAVSALRLGDHVLVRPGARAPVDGVVIDGTSEVDRSALTGEA
HHHCCCCCEEECCCCCHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCHHHHHHHCCCC
MPVMRTVGDPMSTGEVNLTGPLTLEATAVGTDTSLHQLAALVAVAESGRSRYTSLADRAA
HHHHHHCCCCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLYAPGVHILSALAFLGWLLWSGDMRVSLNIAAAVLIITCPCALGLAVPAVTTAASGRLF
HHHCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RKGLLIKNATALERLAEVDTVVFDKTGTVTLGMPRATNWHDLTQDQQSLAYALARGSSHP
HHCCCCCCHHHHHHHHHHHHEEECCCCCEEECCCCCCCCHHHCHHHHHHHHHHHCCCCCH
LAQAIVTAAQDDDTAEIALSNLTEQPGFGTQAHYADRPVRLGRPEWIGALVETDGLCTAL
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEE
DTGEGAPIILRFEDRPRPGAADLMAALKRQGMRVILLSGDRQAPVAQTAAHLGMPDFAAE
ECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCHHHHH
MLPADKVAFVQRLTDEGQRVLMIGDGLNDTGALAAAHVSISPAQALDAARAASDIVLLGQ
HCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHCCEEEECC
DLMPVADAVATARLATKRIRENFQIATVYNIVAVPLAVAGLATPLIAALAMSTSSLTVSV
CHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NALRIRGRG
EEEEEECCC
>Mature Secondary Structure 
TATATNGPASCPGCLSAPAARAEVPLPDAQLALSLPTIHCQACISKVENSLTAHAGVRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCH
ARVNLTRKRVMIDAAPGVTAQELADLVMAAGFEAHELDLGALSQTQTDAASRDILMRLAV
HEEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHH
AGFAAMNVMLLSVAVWSGATDATRDMFHWISAAITLPALAFSAQPFFRNAWAALRAGRLN
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
MDVPITLAIVLAVVTSLWETGLSGKHAYFDAALTLVFFLLAGRWLDSRARSAARSAAEEL
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
TALEVPRAFRIQNGETSEIAVSALRLGDHVLVRPGARAPVDGVVIDGTSEVDRSALTGEA
HHHCCCCCEEECCCCCHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCHHHHHHHCCCC
MPVMRTVGDPMSTGEVNLTGPLTLEATAVGTDTSLHQLAALVAVAESGRSRYTSLADRAA
HHHHHHCCCCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLYAPGVHILSALAFLGWLLWSGDMRVSLNIAAAVLIITCPCALGLAVPAVTTAASGRLF
HHHCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RKGLLIKNATALERLAEVDTVVFDKTGTVTLGMPRATNWHDLTQDQQSLAYALARGSSHP
HHCCCCCCHHHHHHHHHHHHEEECCCCCEEECCCCCCCCHHHCHHHHHHHHHHHCCCCCH
LAQAIVTAAQDDDTAEIALSNLTEQPGFGTQAHYADRPVRLGRPEWIGALVETDGLCTAL
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEE
DTGEGAPIILRFEDRPRPGAADLMAALKRQGMRVILLSGDRQAPVAQTAAHLGMPDFAAE
ECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCHHHHH
MLPADKVAFVQRLTDEGQRVLMIGDGLNDTGALAAAHVSISPAQALDAARAASDIVLLGQ
HCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHCCEEEECC
DLMPVADAVATARLATKRIRENFQIATVYNIVAVPLAVAGLATPLIAALAMSTSSLTVSV
CHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
NALRIRGRG
EEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536685; 11481432 [H]