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The map label for this gene is fnrL [H]

Identifier: 110678593

GI number: 110678593

Start: 1230891

End: 1231634

Strand: Direct

Name: fnrL [H]

Synonym: RD1_1268

Alternate gene names: 110678593

Gene position: 1230891-1231634 (Clockwise)

Preceding gene: 110678591

Following gene: 110678595

Centisome position: 29.78

GC content: 57.12

Gene sequence:

>744_bases
ATGCAAGACGTCGTTGTGCCTAACGTCAAGGAATGCGTGAATTGCCCGATCAGGCATCGCGCTGTTTGTGCACGCTGTGA
CACAGAAGAATTGGCGCTTCTTGAGGATATAAAATACTATCGCAGCTTCTCTGCGGGTCAAACGATCATGTGGTCGGGGG
ACCGCATGGATTTCGTCGCCTCCGTGGTCTCCGGTGTGGCCTCCCTGACCCAAACGATGGAAGACGGGCGCACACAGATG
GTCGGTCTGCTGTTGCCATCGGACTTTGTCGGGCGCCCGGGTCGCGAAATTGCGACTTATACCGTGACTGCGACAAGCGA
CCTTGTCATGTGTTGTTTCAGACGCAAACCCTTTGAGCAGATGATCTCATCGACGCCCCATGTGGCGCATCGCCTGCTTG
AGATGACCCTGGATGAACTGGATGCCGCGCGCGAGTGGATGCTTGTGCTGGGACGCAAGACAGCGCGCGAAAAAATCGCC
AGCCTGCTTGCGATTATTGCCCGGCGCGATGCAATTCTGTCCAAGAATACGGAATCCAACAGCCTTGTCTTTGATCTGCC
GCTGACCCGTGAGGCCATGTCTGATTATCTGGGCCTGACGCTGGAAACCGTCAGCCGACAGATGTCGGCGCTCAAAAAGG
ACGGTGTCGTCGTGCTTGAGGGCAAGCGGCGCATCGTGGTGCCCGATATGGACCGCCTCATGGAAGAGGCGGGGGATGAC
AGCGATGGCGGTATCCTGAGCTGA

Upstream 100 bases:

>100_bases
ATAGACCCAATTTGGCGAGTTTGGATGTCAGTGTCATGGAGACTGGATATGGTTTGTCGGAAGCGGAGACTTTGATGTGG
ATCAAGTGCGGAGAAATTTG

Downstream 100 bases:

>100_bases
CATGCGCTCGGGTCGCGAGGGCTAGTGTGCCATCATGACCGGCACCTTGCTGTGCTCCAGCATGTCGCGGGTGGCACCAC
CCAGAACGGCTTCGCGGAAA

Product: transcriptional activator protein FnrL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MQDVVVPNVKECVNCPIRHRAVCARCDTEELALLEDIKYYRSFSAGQTIMWSGDRMDFVASVVSGVASLTQTMEDGRTQM
VGLLLPSDFVGRPGREIATYTVTATSDLVMCCFRRKPFEQMISSTPHVAHRLLEMTLDELDAAREWMLVLGRKTAREKIA
SLLAIIARRDAILSKNTESNSLVFDLPLTREAMSDYLGLTLETVSRQMSALKKDGVVVLEGKRRIVVPDMDRLMEEAGDD
SDGGILS

Sequences:

>Translated_247_residues
MQDVVVPNVKECVNCPIRHRAVCARCDTEELALLEDIKYYRSFSAGQTIMWSGDRMDFVASVVSGVASLTQTMEDGRTQM
VGLLLPSDFVGRPGREIATYTVTATSDLVMCCFRRKPFEQMISSTPHVAHRLLEMTLDELDAAREWMLVLGRKTAREKIA
SLLAIIARRDAILSKNTESNSLVFDLPLTREAMSDYLGLTLETVSRQMSALKKDGVVVLEGKRRIVVPDMDRLMEEAGDD
SDGGILS
>Mature_247_residues
MQDVVVPNVKECVNCPIRHRAVCARCDTEELALLEDIKYYRSFSAGQTIMWSGDRMDFVASVVSGVASLTQTMEDGRTQM
VGLLLPSDFVGRPGREIATYTVTATSDLVMCCFRRKPFEQMISSTPHVAHRLLEMTLDELDAAREWMLVLGRKTAREKIA
SLLAIIARRDAILSKNTESNSLVFDLPLTREAMSDYLGLTLETVSRQMSALKKDGVVVLEGKRRIVVPDMDRLMEEAGDD
SDGGILS

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=233, Percent_Identity=26.1802575107296, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27481; Mature: 27481

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDVVVPNVKECVNCPIRHRAVCARCDTEELALLEDIKYYRSFSAGQTIMWSGDRMDFVA
CCCCCCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHH
SVVSGVASLTQTMEDGRTQMVGLLLPSDFVGRPGREIATYTVTATSDLVMCCFRRKPFEQ
HHHHHHHHHHHHHHCCHHHEEEEECCCHHCCCCCCCEEEEEEECHHHHHHHHHCCCCHHH
MISSTPHVAHRLLEMTLDELDAAREWMLVLGRKTAREKIASLLAIIARRDAILSKNTESN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SLVFDLPLTREAMSDYLGLTLETVSRQMSALKKDGVVVLEGKRRIVVPDMDRLMEEAGDD
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCCHHHHHHHCCCC
SDGGILS
CCCCCCC
>Mature Secondary Structure
MQDVVVPNVKECVNCPIRHRAVCARCDTEELALLEDIKYYRSFSAGQTIMWSGDRMDFVA
CCCCCCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHH
SVVSGVASLTQTMEDGRTQMVGLLLPSDFVGRPGREIATYTVTATSDLVMCCFRRKPFEQ
HHHHHHHHHHHHHHCCHHHEEEEECCCHHCCCCCCCEEEEEEECHHHHHHHHHCCCCHHH
MISSTPHVAHRLLEMTLDELDAAREWMLVLGRKTAREKIASLLAIIARRDAILSKNTESN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SLVFDLPLTREAMSDYLGLTLETVSRQMSALKKDGVVVLEGKRRIVVPDMDRLMEEAGDD
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEECCCHHHHHHHCCCC
SDGGILS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]