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The map label for this gene is rodA [H]

Identifier: 110678533

GI number: 110678533

Start: 1168183

End: 1169322

Strand: Reverse

Name: rodA [H]

Synonym: RD1_1205

Alternate gene names: 110678533

Gene position: 1169322-1168183 (Counterclockwise)

Preceding gene: 110678534

Following gene: 110678532

Centisome position: 28.29

GC content: 57.11

Gene sequence:

>1140_bases
ATGAGTTATCTCGAGCATAACGTCAAATCCACGCCCGTGGGCTTGCGCAAGATCCTGCACCTCAACTGGCCCGTTGCGAT
CCTGCTGGCCGCAGTTGCGGGCGTCGGTTTCCTGATGCTCTACTCGGTTGCGGGCGGGTCATTCTCCCCCTGGGCCGAGC
CGCAGATGAAGCGGTTCGTCGTCGGTTTCGCCCTGATGCTGATTGTGGCCATGGTTCCCATCTGGTTCTGGCGCAGCCTG
TCCGGCCTTGCCTATCTCGGCACGCTTGTCTTGCTGGTTGCGGTTGAATTGTTCGGCACCGTCGGCATGGGGGCGCAACG
ATGGATCGACCTTGGTTTCATGCGATTGCAGCCCTCGGAACTGATGAAAATCACATTGGTGATGCTGCTGGCGGCCTATT
ATGACTGGCTGCCAGCCAAGAAAACATCGCGTCCCTTATGGGTGATCCTACCGGTTATCATCATCATAATCCCCGTTCTT
CTGGTACTGCGTCAACCGGATCTGGGCACGTCAATTCTGCTGCTGGCCGCCGGGGGCGGTTTGATGTTTCTGGCGGGGGT
GCACTGGGCCTATTTTGCCGCTGTTGCAGCCAGCGGTGTGGCGCTGGTCACTGCGGTGTTCAAATCCCGCGGCACACCTT
GGCAGCTTATTGAAAACTATCAGTTCCGCCGGATAGACACTTTTCTGGACCCCAGCACCGATCCTCTGGGCGCCGGGTAT
CACATCACGCAATCAAAGATCGCGCTTGGCTCTGGTGGATGGACCGGGCGCGGTTTCATGCAGGGCACGCAAAGCCGTCT
GAACTTTTTGCCCGAAAAACACACGGACTTTATCTTTACTACGCTGGCAGAGGAATTCGGCTTCATTGGCGCGATTTCAT
TGCTTGCGCTTTATACGCTGATCATTGTCTTTTGCGTCTGGTCCGCCATGCTGAACAAGGACCGGTTTTCATCGCTGCTG
ACCCTTGGGATTGCGCTGAACTTCTTTTTGTTCTTTGCGGTCAACATGTCGATGGTCATGGGGCTTGCGCCGGTTGTCGG
GGTCCCGCTCCCGCTGGTGAGCTTTGGGGGTTCGGCCATGCTGGTTTTGATGCTTGCCTTCGGGCTGACGCAAAGTGCGC
ATGTGCACCGCCCCAGATAA

Upstream 100 bases:

>100_bases
TTGAGGCATACCCGGCCAAGGACCGCGAACGCATCGGCACGCTGCAAAAAGAATTGCAAAAGATGCAGCCACAGGCCGCT
ATCAGCGGGCGGGATCAGGC

Downstream 100 bases:

>100_bases
AGGCCAGATAAAGGACCGACATGACCCTGACCGTTTTGTTCGCCGCCAGCAATGAGGACTGGCACAAGTACGGCCGCGCA
CTGAGCGATGCCTTTACCCA

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSYLEHNVKSTPVGLRKILHLNWPVAILLAAVAGVGFLMLYSVAGGSFSPWAEPQMKRFVVGFALMLIVAMVPIWFWRSL
SGLAYLGTLVLLVAVELFGTVGMGAQRWIDLGFMRLQPSELMKITLVMLLAAYYDWLPAKKTSRPLWVILPVIIIIIPVL
LVLRQPDLGTSILLLAAGGGLMFLAGVHWAYFAAVAASGVALVTAVFKSRGTPWQLIENYQFRRIDTFLDPSTDPLGAGY
HITQSKIALGSGGWTGRGFMQGTQSRLNFLPEKHTDFIFTTLAEEFGFIGAISLLALYTLIIVFCVWSAMLNKDRFSSLL
TLGIALNFFLFFAVNMSMVMGLAPVVGVPLPLVSFGGSAMLVLMLAFGLTQSAHVHRPR

Sequences:

>Translated_379_residues
MSYLEHNVKSTPVGLRKILHLNWPVAILLAAVAGVGFLMLYSVAGGSFSPWAEPQMKRFVVGFALMLIVAMVPIWFWRSL
SGLAYLGTLVLLVAVELFGTVGMGAQRWIDLGFMRLQPSELMKITLVMLLAAYYDWLPAKKTSRPLWVILPVIIIIIPVL
LVLRQPDLGTSILLLAAGGGLMFLAGVHWAYFAAVAASGVALVTAVFKSRGTPWQLIENYQFRRIDTFLDPSTDPLGAGY
HITQSKIALGSGGWTGRGFMQGTQSRLNFLPEKHTDFIFTTLAEEFGFIGAISLLALYTLIIVFCVWSAMLNKDRFSSLL
TLGIALNFFLFFAVNMSMVMGLAPVVGVPLPLVSFGGSAMLVLMLAFGLTQSAHVHRPR
>Mature_378_residues
SYLEHNVKSTPVGLRKILHLNWPVAILLAAVAGVGFLMLYSVAGGSFSPWAEPQMKRFVVGFALMLIVAMVPIWFWRSLS
GLAYLGTLVLLVAVELFGTVGMGAQRWIDLGFMRLQPSELMKITLVMLLAAYYDWLPAKKTSRPLWVILPVIIIIIPVLL
VLRQPDLGTSILLLAAGGGLMFLAGVHWAYFAAVAASGVALVTAVFKSRGTPWQLIENYQFRRIDTFLDPSTDPLGAGYH
ITQSKIALGSGGWTGRGFMQGTQSRLNFLPEKHTDFIFTTLAEEFGFIGAISLLALYTLIIVFCVWSAMLNKDRFSSLLT
LGIALNFFLFFAVNMSMVMGLAPVVGVPLPLVSFGGSAMLVLMLAFGLTQSAHVHRPR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=340, Percent_Identity=42.0588235294118, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1786277, Length=349, Percent_Identity=33.810888252149, Blast_Score=172, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41488; Mature: 41357

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLEHNVKSTPVGLRKILHLNWPVAILLAAVAGVGFLMLYSVAGGSFSPWAEPQMKRFV
CCCHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
VGFALMLIVAMVPIWFWRSLSGLAYLGTLVLLVAVELFGTVGMGAQRWIDLGFMRLQPSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHH
LMKITLVMLLAAYYDWLPAKKTSRPLWVILPVIIIIIPVLLVLRQPDLGTSILLLAAGGG
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
LMFLAGVHWAYFAAVAASGVALVTAVFKSRGTPWQLIENYQFRRIDTFLDPSTDPLGAGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCE
HITQSKIALGSGGWTGRGFMQGTQSRLNFLPEKHTDFIFTTLAEEFGFIGAISLLALYTL
EEECCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IIVFCVWSAMLNKDRFSSLLTLGIALNFFLFFAVNMSMVMGLAPVVGVPLPLVSFGGSAM
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHH
LVLMLAFGLTQSAHVHRPR
HHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SYLEHNVKSTPVGLRKILHLNWPVAILLAAVAGVGFLMLYSVAGGSFSPWAEPQMKRFV
CCHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
VGFALMLIVAMVPIWFWRSLSGLAYLGTLVLLVAVELFGTVGMGAQRWIDLGFMRLQPSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHH
LMKITLVMLLAAYYDWLPAKKTSRPLWVILPVIIIIIPVLLVLRQPDLGTSILLLAAGGG
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
LMFLAGVHWAYFAAVAASGVALVTAVFKSRGTPWQLIENYQFRRIDTFLDPSTDPLGAGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCE
HITQSKIALGSGGWTGRGFMQGTQSRLNFLPEKHTDFIFTTLAEEFGFIGAISLLALYTL
EEECCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IIVFCVWSAMLNKDRFSSLLTLGIALNFFLFFAVNMSMVMGLAPVVGVPLPLVSFGGSAM
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHH
LVLMLAFGLTQSAHVHRPR
HHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]