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The map label for this gene is trpS [H]

Identifier: 110678514

GI number: 110678514

Start: 1147425

End: 1148438

Strand: Reverse

Name: trpS [H]

Synonym: RD1_1185

Alternate gene names: 110678514

Gene position: 1148438-1147425 (Counterclockwise)

Preceding gene: 110678516

Following gene: 110678513

Centisome position: 27.79

GC content: 58.68

Gene sequence:

>1014_bases
ATGACCAGCCCCACCTTCGCCCCCCGTGTTTTTTCCGGCATCCAGCCTTCGGGCGGTCTGACGCTGGGCAATTACCTCGG
CGCGATCAAGCGTTTTGTTGCGATGCAGGATGATTTTCCCTGCGTCTACTGCATGGTGGATTTGCATGCGATCACCGTCT
GGCAGGACCCCAAGGACCTTGCGCATAACACGCGCGAATTGGCCGCCGGGTTTATCGCATCGGGCATCAGCCCTGAGAAG
TCGATCCTGATCAACCAAAGCCAGGTGCCCGAACATGCGCAACTCGGCTGGGTCTTCAACTGCGTGGCCCGCATGGGCTG
GATGCAGCGGATGACGCAATTCAAGGACAAGGCGGGCAAAAACGCGCAGAATGCATCGCTCGGTCTGTTTGGCTATCCGG
CGCTGATGGCGGCTGATATCCTGATCTATCATGCAACGCATGTCCCGGTCGGCGAGGATCAGAAGCAGCACCTCGAACTG
ACACGCGATATTGCTGCCAAGTTCAACCATGACTACGGCGTTGATTTCTTTCCGCTGACCGAACCCGTAATCGAAGGGGC
GGCAACCCGGGTCATGTCCCTGCGCGACGGGTCCAAGAAGATGTCGAAATCCGATCCATCGGATGCCAGCCGGATCAATA
TGACCGATGATGCGGACGCAATTGCGAGGAAGATCCGCAAAGCCAAAACCGATCCGGATGCCCTGCCGTCGGAAATCGAC
GGGCTGAAAGATCGCCCGGAAGCGCGCAATCTTGTAAACATATACGCAGCCCTGAACGACCAGACCGTCGAAGACGTGCT
GGCGGATGTGGGTGGCCAGCAATTCGGGACCTTCAAGCCGCAGTTGGCGGAGCTTGCGGTCTCGAAACTCTCGCCGGTAT
CGCGGGAAATGGCGCGGCTGATGGATGACCCGGCAGAGATCGACCGCATCCTTGCCAAAGGTGCCGCACAGGCGCGCGAA
ATCACAGCGCCCATCCTGCACAAAACCTACGAAGTCATGGGCATGGTGCGCTAG

Upstream 100 bases:

>100_bases
GTGTTCTGCGTCTCGTTCATAGTGCGGGGTTCCTTGACGATGCTCTGGCTCATGGGTAAGCCAGCGCAGACTTCATTGCC
AGCGAGAACGGACGCCTTTC

Downstream 100 bases:

>100_bases
TCGCACCCGCCGTTTTGTCGAGCCAAACAGGCATGTTGGCAACGGCGTCTGCGCAGAAAATGGCGCGTGGACTTTTCCCG
GCGGCTGCTTCACTCTGCTG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTSPTFAPRVFSGIQPSGGLTLGNYLGAIKRFVAMQDDFPCVYCMVDLHAITVWQDPKDLAHNTRELAAGFIASGISPEK
SILINQSQVPEHAQLGWVFNCVARMGWMQRMTQFKDKAGKNAQNASLGLFGYPALMAADILIYHATHVPVGEDQKQHLEL
TRDIAAKFNHDYGVDFFPLTEPVIEGAATRVMSLRDGSKKMSKSDPSDASRINMTDDADAIARKIRKAKTDPDALPSEID
GLKDRPEARNLVNIYAALNDQTVEDVLADVGGQQFGTFKPQLAELAVSKLSPVSREMARLMDDPAEIDRILAKGAAQARE
ITAPILHKTYEVMGMVR

Sequences:

>Translated_337_residues
MTSPTFAPRVFSGIQPSGGLTLGNYLGAIKRFVAMQDDFPCVYCMVDLHAITVWQDPKDLAHNTRELAAGFIASGISPEK
SILINQSQVPEHAQLGWVFNCVARMGWMQRMTQFKDKAGKNAQNASLGLFGYPALMAADILIYHATHVPVGEDQKQHLEL
TRDIAAKFNHDYGVDFFPLTEPVIEGAATRVMSLRDGSKKMSKSDPSDASRINMTDDADAIARKIRKAKTDPDALPSEID
GLKDRPEARNLVNIYAALNDQTVEDVLADVGGQQFGTFKPQLAELAVSKLSPVSREMARLMDDPAEIDRILAKGAAQARE
ITAPILHKTYEVMGMVR
>Mature_336_residues
TSPTFAPRVFSGIQPSGGLTLGNYLGAIKRFVAMQDDFPCVYCMVDLHAITVWQDPKDLAHNTRELAAGFIASGISPEKS
ILINQSQVPEHAQLGWVFNCVARMGWMQRMTQFKDKAGKNAQNASLGLFGYPALMAADILIYHATHVPVGEDQKQHLELT
RDIAAKFNHDYGVDFFPLTEPVIEGAATRVMSLRDGSKKMSKSDPSDASRINMTDDADAIARKIRKAKTDPDALPSEIDG
LKDRPEARNLVNIYAALNDQTVEDVLADVGGQQFGTFKPQLAELAVSKLSPVSREMARLMDDPAEIDRILAKGAAQAREI
TAPILHKTYEVMGMVR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=330, Percent_Identity=42.7272727272727, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI41352700, Length=177, Percent_Identity=53.1073446327684, Blast_Score=198, Evalue=6e-51,
Organism=Escherichia coli, GI1789786, Length=329, Percent_Identity=44.6808510638298, Blast_Score=296, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI71982800, Length=341, Percent_Identity=33.1378299120235, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=33.1378299120235, Blast_Score=187, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6320474, Length=346, Percent_Identity=39.5953757225434, Blast_Score=230, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24666151, Length=332, Percent_Identity=39.7590361445783, Blast_Score=232, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37001; Mature: 36870

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTFAPRVFSGIQPSGGLTLGNYLGAIKRFVAMQDDFPCVYCMVDLHAITVWQDPKDL
CCCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEEECCHHHH
AHNTRELAAGFIASGISPEKSILINQSQVPEHAQLGWVFNCVARMGWMQRMTQFKDKAGK
HHHHHHHHHHHHHCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NAQNASLGLFGYPALMAADILIYHATHVPVGEDQKQHLELTRDIAAKFNHDYGVDFFPLT
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
EPVIEGAATRVMSLRDGSKKMSKSDPSDASRINMTDDADAIARKIRKAKTDPDALPSEID
HHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHC
GLKDRPEARNLVNIYAALNDQTVEDVLADVGGQQFGTFKPQLAELAVSKLSPVSREMARL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
MDDPAEIDRILAKGAAQAREITAPILHKTYEVMGMVR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSPTFAPRVFSGIQPSGGLTLGNYLGAIKRFVAMQDDFPCVYCMVDLHAITVWQDPKDL
CCCCCCHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEEECCHHHH
AHNTRELAAGFIASGISPEKSILINQSQVPEHAQLGWVFNCVARMGWMQRMTQFKDKAGK
HHHHHHHHHHHHHCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NAQNASLGLFGYPALMAADILIYHATHVPVGEDQKQHLELTRDIAAKFNHDYGVDFFPLT
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
EPVIEGAATRVMSLRDGSKKMSKSDPSDASRINMTDDADAIARKIRKAKTDPDALPSEID
HHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHC
GLKDRPEARNLVNIYAALNDQTVEDVLADVGGQQFGTFKPQLAELAVSKLSPVSREMARL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
MDDPAEIDRILAKGAAQAREITAPILHKTYEVMGMVR
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]