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The map label for this gene is nahR [H]

Identifier: 110678499

GI number: 110678499

Start: 1132531

End: 1133445

Strand: Reverse

Name: nahR [H]

Synonym: RD1_1169

Alternate gene names: 110678499

Gene position: 1133445-1132531 (Counterclockwise)

Preceding gene: 110678501

Following gene: 110678498

Centisome position: 27.42

GC content: 53.01

Gene sequence:

>915_bases
ATGAAAAATTTCGATGTTTTGTCAATTGACGGTAAGCTTTTGAAGGTCTTCCTGACCGTTTTCCAAGAAAAATCAGTGAC
CAAAGCAGCCTGCGCTCTGGGCACCAGCCAATCGACCATAAGCCACAGTCTCGAAAAGCTTCGTCACTGCGTTGGCGACC
CGCTTTTTGTCAAATCTGGCAGGGGTATTGCGCCGACAAATGTCGCTGCAGCGCTTGCACCGAAAGTCTGCCGGATCATC
AGTGAGCTTGAAGGGCTTGCCATGCAATCCGAGTACTGCCCGCGGCAGGATACGACAACTCTGACAATAACCACCAACGT
GACCGAACTATTGCCGGTGCTGATCCCCGTAAAACAGGCGATCAGACAGGCAGCACCGGACGTCACGATCCGTTTTACCG
ACCTTGGTGCGCGCACCAACGCATTGAGCGTATTGGCAAACGGGCTCGCGGATGTCGCGATCACCGCCTCGATAGGTCCC
TACCCTTTGGAGCTGGCGATAGATCAATATTACAAGGATGATTTCGTTTGCTATTTTGACTGTGAACAACGCAACGCACC
AGATACTGTTGAGGCATATGGCAAGGCGCGGCATGCGGTGCTCGACTTTGGCGGCGCCACCAAAAGCATTGTCGATGCAG
CATTGGAAAATGCGGGGCAGACACGCGAAATCCATCTGGCAGCGGCGAACTCCTATGCCCTTGCAAAGCTTGCCTCGGGT
ACGGATTTGGTTGCCACGTTGCCAAAGCGCCTCAGAGCAACGGCGTTCAAGGGATTTGCCTATGTAACGCCCCCGTTTCC
GCTGCCACCCGTAACCTATGATCTGGTTTGGCATCGTCGCACCTTGGACAGTTCACGCCACAAGTGGCTGAGACAAACAA
TGATGGCTGCGATTTCAAATTTTGAAGTGAAATAG

Upstream 100 bases:

>100_bases
TTTTCATTCAGAAAGCCCTATCGCGATGCTTAAAAAACCCTCACTAATTTAATAATGATTGGAGTTACAGATTGATCAAT
TTAGAAAAACTTAAAAATCC

Downstream 100 bases:

>100_bases
CCGGACCAGCGGCATGGAAAAGAACGACCTTCCCGGCATTTGACTGGACACGGATTTTTGCAGTTCTGCGACCGTCTCGC
AGACGACGCCGAAATCGCAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKNFDVLSIDGKLLKVFLTVFQEKSVTKAACALGTSQSTISHSLEKLRHCVGDPLFVKSGRGIAPTNVAAALAPKVCRII
SELEGLAMQSEYCPRQDTTTLTITTNVTELLPVLIPVKQAIRQAAPDVTIRFTDLGARTNALSVLANGLADVAITASIGP
YPLELAIDQYYKDDFVCYFDCEQRNAPDTVEAYGKARHAVLDFGGATKSIVDAALENAGQTREIHLAAANSYALAKLASG
TDLVATLPKRLRATAFKGFAYVTPPFPLPPVTYDLVWHRRTLDSSRHKWLRQTMMAAISNFEVK

Sequences:

>Translated_304_residues
MKNFDVLSIDGKLLKVFLTVFQEKSVTKAACALGTSQSTISHSLEKLRHCVGDPLFVKSGRGIAPTNVAAALAPKVCRII
SELEGLAMQSEYCPRQDTTTLTITTNVTELLPVLIPVKQAIRQAAPDVTIRFTDLGARTNALSVLANGLADVAITASIGP
YPLELAIDQYYKDDFVCYFDCEQRNAPDTVEAYGKARHAVLDFGGATKSIVDAALENAGQTREIHLAAANSYALAKLASG
TDLVATLPKRLRATAFKGFAYVTPPFPLPPVTYDLVWHRRTLDSSRHKWLRQTMMAAISNFEVK
>Mature_304_residues
MKNFDVLSIDGKLLKVFLTVFQEKSVTKAACALGTSQSTISHSLEKLRHCVGDPLFVKSGRGIAPTNVAAALAPKVCRII
SELEGLAMQSEYCPRQDTTTLTITTNVTELLPVLIPVKQAIRQAAPDVTIRFTDLGARTNALSVLANGLADVAITASIGP
YPLELAIDQYYKDDFVCYFDCEQRNAPDTVEAYGKARHAVLDFGGATKSIVDAALENAGQTREIHLAAANSYALAKLASG
TDLVATLPKRLRATAFKGFAYVTPPFPLPPVTYDLVWHRRTLDSSRHKWLRQTMMAAISNFEVK

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081766, Length=271, Percent_Identity=26.1992619926199, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790147, Length=296, Percent_Identity=22.6351351351351, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33086; Mature: 33086

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFDVLSIDGKLLKVFLTVFQEKSVTKAACALGTSQSTISHSLEKLRHCVGDPLFVKSG
CCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECC
RGIAPTNVAAALAPKVCRIISELEGLAMQSEYCPRQDTTTLTITTNVTELLPVLIPVKQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHH
IRQAAPDVTIRFTDLGARTNALSVLANGLADVAITASIGPYPLELAIDQYYKDDFVCYFD
HHHCCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCCCEEEEEE
CEQRNAPDTVEAYGKARHAVLDFGGATKSIVDAALENAGQTREIHLAAANSYALAKLASG
CCCCCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCC
TDLVATLPKRLRATAFKGFAYVTPPFPLPPVTYDLVWHRRTLDSSRHKWLRQTMMAAISN
CHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHC
FEVK
CCCC
>Mature Secondary Structure
MKNFDVLSIDGKLLKVFLTVFQEKSVTKAACALGTSQSTISHSLEKLRHCVGDPLFVKSG
CCCCEEEEECHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECC
RGIAPTNVAAALAPKVCRIISELEGLAMQSEYCPRQDTTTLTITTNVTELLPVLIPVKQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHH
IRQAAPDVTIRFTDLGARTNALSVLANGLADVAITASIGPYPLELAIDQYYKDDFVCYFD
HHHCCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCCCCEEEEEE
CEQRNAPDTVEAYGKARHAVLDFGGATKSIVDAALENAGQTREIHLAAANSYALAKLASG
CCCCCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCC
TDLVATLPKRLRATAFKGFAYVTPPFPLPPVTYDLVWHRRTLDSSRHKWLRQTMMAAISN
CHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHC
FEVK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]