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The map label for this gene is appB [H]

Identifier: 110678436

GI number: 110678436

Start: 1051155

End: 1052183

Strand: Reverse

Name: appB [H]

Synonym: RD1_1100

Alternate gene names: 110678436

Gene position: 1052183-1051155 (Counterclockwise)

Preceding gene: 110678437

Following gene: 110678435

Centisome position: 25.46

GC content: 57.73

Gene sequence:

>1029_bases
ATGATGTTTCTCCGCTACGCCATCTATCGGTTTATCACGATGCTGCTGACCCTCTGGGTCGTGTCGCTGCTGATTTTCGT
GATCATCAATCTGCCTCCGGGGGATTACCTGAGCAACCAGATTGCCGAGTTGCGCGCAACAGGTCAGGCCGAAGGTGTGG
CAAAGGCGGAATTCCTGCGCACCGAATATGCGCTGGATCGCCCGATCTGGGAACAATATCTCATCTGGGTTGGCATGGCC
CCCGGCCCGCAGGGCTGGTACGGGTTGATACAGGGCAATTTTGGCTGGTCCTTTGAATTTGACCGCCCCGTCGATGAAAT
CGTCGGCGACGCGCTGTGGCTGACGGTACTGGTCAACCTCGCCGCGGTGCTGTTTGTCTATATGGTCGCGTTGCCCTTGG
GGGTTCTGGCGGCGGCGCGCTCTGAAACATGGGTCGATTATACGGCGGCTTTCGTCGGGTATCTTGGCTTGGCCACACCG
AACTTTTTGCTCGCCCTGATGCTGTTTTACTACGGCAACAAGTACTTTGATCTGCCCATTGGTGGCCTGATGGACCCAAG
GTTCGAGGGGCAGCCGATGTCGTGGGACAAGGTGCATTCCATTCTGATCCATCTGATTGTGCCGACCTTTGTGATCGGAA
CATCCGGGGCTGCCGCGATGATGCAACGCCTGCGCGCCAATATGCTGGATGAACTCAGCAAGCCCTATGTAGAAACGGCC
AAGGCCAAGGGGCTGGCCCCCTCGAAACTGTTGGCGAAATATCCGCTGCGTATGGCGTTCAACCCTTTCGTGGCAGACAT
CGGCAACCTGTTGCCTGCGATGGTGTCAGGCTCTGTGCTCGTGTCTGTGGTTCTGGGGTTGCAAACGATTGGCCCATCGC
TGCTGACGGCACTCAAATCGCAGGATCAGTTTCTGGCCGGGTTCATCCTGATGTTCGTGGCCCTGCTGACCCTGATCGGC
ACGATGGTGTCTGATCTGTTGCTGGTGCTGCTGGATCCGCGCATCAGATACGGGGCGCGCGGGCGATGA

Upstream 100 bases:

>100_bases
TGCCGGAAACAGGCAAATGGGCATGGGATCCGGGGGCGCATTTCGGCATCCACCGCATAGACGAATTTTACTACGAAGAC
GCCTTTCAGCAGTTCACCCA

Downstream 100 bases:

>100_bases
CAAGAATGCCAGACGGTCGCTATGTCGACGACGCCCCCTATACCGATGATGTGGACCTCAGCGCGCTTGAACGCTCTGAT
ATGGATGCGCCGAACTGGGT

Product: oligopeptide ABC transporter, permease protein, putative

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MMFLRYAIYRFITMLLTLWVVSLLIFVIINLPPGDYLSNQIAELRATGQAEGVAKAEFLRTEYALDRPIWEQYLIWVGMA
PGPQGWYGLIQGNFGWSFEFDRPVDEIVGDALWLTVLVNLAAVLFVYMVALPLGVLAAARSETWVDYTAAFVGYLGLATP
NFLLALMLFYYGNKYFDLPIGGLMDPRFEGQPMSWDKVHSILIHLIVPTFVIGTSGAAAMMQRLRANMLDELSKPYVETA
KAKGLAPSKLLAKYPLRMAFNPFVADIGNLLPAMVSGSVLVSVVLGLQTIGPSLLTALKSQDQFLAGFILMFVALLTLIG
TMVSDLLLVLLDPRIRYGARGR

Sequences:

>Translated_342_residues
MMFLRYAIYRFITMLLTLWVVSLLIFVIINLPPGDYLSNQIAELRATGQAEGVAKAEFLRTEYALDRPIWEQYLIWVGMA
PGPQGWYGLIQGNFGWSFEFDRPVDEIVGDALWLTVLVNLAAVLFVYMVALPLGVLAAARSETWVDYTAAFVGYLGLATP
NFLLALMLFYYGNKYFDLPIGGLMDPRFEGQPMSWDKVHSILIHLIVPTFVIGTSGAAAMMQRLRANMLDELSKPYVETA
KAKGLAPSKLLAKYPLRMAFNPFVADIGNLLPAMVSGSVLVSVVLGLQTIGPSLLTALKSQDQFLAGFILMFVALLTLIG
TMVSDLLLVLLDPRIRYGARGR
>Mature_342_residues
MMFLRYAIYRFITMLLTLWVVSLLIFVIINLPPGDYLSNQIAELRATGQAEGVAKAEFLRTEYALDRPIWEQYLIWVGMA
PGPQGWYGLIQGNFGWSFEFDRPVDEIVGDALWLTVLVNLAAVLFVYMVALPLGVLAAARSETWVDYTAAFVGYLGLATP
NFLLALMLFYYGNKYFDLPIGGLMDPRFEGQPMSWDKVHSILIHLIVPTFVIGTSGAAAMMQRLRANMLDELSKPYVETA
KAKGLAPSKLLAKYPLRMAFNPFVADIGNLLPAMVSGSVLVSVVLGLQTIGPSLLTALKSQDQFLAGFILMFVALLTLIG
TMVSDLLLVLLDPRIRYGARGR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788504, Length=373, Percent_Identity=27.8820375335121, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787053, Length=339, Percent_Identity=30.0884955752212, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789965, Length=350, Percent_Identity=26.2857142857143, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1789888, Length=335, Percent_Identity=27.4626865671642, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787497, Length=336, Percent_Identity=24.4047619047619, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787761, Length=320, Percent_Identity=26.875, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787550, Length=281, Percent_Identity=22.4199288256228, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37889; Mature: 37889

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFLRYAIYRFITMLLTLWVVSLLIFVIINLPPGDYLSNQIAELRATGQAEGVAKAEFLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
TEYALDRPIWEQYLIWVGMAPGPQGWYGLIQGNFGWSFEFDRPVDEIVGDALWLTVLVNL
HHHHHCCHHHHHHHHHEECCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AAVLFVYMVALPLGVLAAARSETWVDYTAAFVGYLGLATPNFLLALMLFYYGNKYFDLPI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCC
GGLMDPRFEGQPMSWDKVHSILIHLIVPTFVIGTSGAAAMMQRLRANMLDELSKPYVETA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHH
KAKGLAPSKLLAKYPLRMAFNPFVADIGNLLPAMVSGSVLVSVVLGLQTIGPSLLTALKS
HHCCCCHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
QDQFLAGFILMFVALLTLIGTMVSDLLLVLLDPRIRYGARGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMFLRYAIYRFITMLLTLWVVSLLIFVIINLPPGDYLSNQIAELRATGQAEGVAKAEFLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
TEYALDRPIWEQYLIWVGMAPGPQGWYGLIQGNFGWSFEFDRPVDEIVGDALWLTVLVNL
HHHHHCCHHHHHHHHHEECCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AAVLFVYMVALPLGVLAAARSETWVDYTAAFVGYLGLATPNFLLALMLFYYGNKYFDLPI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCC
GGLMDPRFEGQPMSWDKVHSILIHLIVPTFVIGTSGAAAMMQRLRANMLDELSKPYVETA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHH
KAKGLAPSKLLAKYPLRMAFNPFVADIGNLLPAMVSGSVLVSVVLGLQTIGPSLLTALKS
HHCCCCHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
QDQFLAGFILMFVALLTLIGTMVSDLLLVLLDPRIRYGARGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]