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The map label for this gene is lolD [H]

Identifier: 110678368

GI number: 110678368

Start: 992125

End: 992904

Strand: Direct

Name: lolD [H]

Synonym: RD1_1025

Alternate gene names: 110678368

Gene position: 992125-992904 (Clockwise)

Preceding gene: 110678367

Following gene: 110678369

Centisome position: 24.0

GC content: 63.97

Gene sequence:

>780_bases
ATGGCCTATTCGCTCGCAATTGACGATCTGACGGTGACGCTTGGCGATGCAGAACGCCGCTTTACGCTGCAAGCGGGGCA
GTGGTCGATTGCGGCGGGGGAGGTCATTGGGCTGACCGGACCATCGGGCACCGGCAAGACGCTGCTGCTGGAACTGCTTG
GCATGTTACGCGCGCCCGATCGCGGCAGCTATATCGCCACGCCACTGGCAGGCACCGCTGGCACGCGGCAGGAGTTTCAC
AGCTTTTGGCAGGACGCGAATGCAATGGCGCTGTGTGCCGGGGCGCGTGCGGGGTTCTTTGGGTTTGTGCCACAGGCGGG
CGGGCTATTGCCGTTTCTGACCGTCACCGAGAACGTGGAAATCACGCAGCGGATCGCGCAGCGTCCTGACGAAAGCTGGC
TCAAGGCGCTGTTGGGTGAATTGGGTCTGAGCCAGATCGCGCATTTGCGCCCCGGTGCCTTGTCCATCGGTCAACGCCAG
CGGGTGGCGATTGCGCGCGCGCTGGCCCATCGCCCGTTTTGCGTGATCGCGGATGAGCCGACCGCAGCGCTCGATCCGGA
AAATGCACAAGTCGCCATGGGCCTGTTGATCGAGGCCGCGCGCGCCGGGGGCACGGCGACCCTGTTGTCGAGCCACGATT
ACCCGACGCTGGAAAAGTTCGAGATGCGGCGCATGAGGTTGCAGATCACCTCGGCACCGCATGACCCGGATGTGGTCAGC
ACCCTCGTGGCCATGAACACACAAGGCGCGACATCGCCATCTGACCGGGTAGACGTCTGA

Upstream 100 bases:

>100_bases
GCTGTTTGACCCGCAGGTCTGGACCGCGCTGCACGACGGGGCCGATGATGGGGAGCTGGTCTTTGCCATGCCCTTTGACG
TTTTGCCCTGAGGCGCGGCG

Downstream 100 bases:

>100_bases
TGCTGATCCTGCGTCTTGCTCTGCGTGATCTGTTTTTCCAGAAGGTGCATCTGATCTGCAACATCGCGGTGCTGGCCGGG
GTTCTGGTGCCGCTTCTGGT

Product: ABC transporter, ATP-binding protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MAYSLAIDDLTVTLGDAERRFTLQAGQWSIAAGEVIGLTGPSGTGKTLLLELLGMLRAPDRGSYIATPLAGTAGTRQEFH
SFWQDANAMALCAGARAGFFGFVPQAGGLLPFLTVTENVEITQRIAQRPDESWLKALLGELGLSQIAHLRPGALSIGQRQ
RVAIARALAHRPFCVIADEPTAALDPENAQVAMGLLIEAARAGGTATLLSSHDYPTLEKFEMRRMRLQITSAPHDPDVVS
TLVAMNTQGATSPSDRVDV

Sequences:

>Translated_259_residues
MAYSLAIDDLTVTLGDAERRFTLQAGQWSIAAGEVIGLTGPSGTGKTLLLELLGMLRAPDRGSYIATPLAGTAGTRQEFH
SFWQDANAMALCAGARAGFFGFVPQAGGLLPFLTVTENVEITQRIAQRPDESWLKALLGELGLSQIAHLRPGALSIGQRQ
RVAIARALAHRPFCVIADEPTAALDPENAQVAMGLLIEAARAGGTATLLSSHDYPTLEKFEMRRMRLQITSAPHDPDVVS
TLVAMNTQGATSPSDRVDV
>Mature_258_residues
AYSLAIDDLTVTLGDAERRFTLQAGQWSIAAGEVIGLTGPSGTGKTLLLELLGMLRAPDRGSYIATPLAGTAGTRQEFHS
FWQDANAMALCAGARAGFFGFVPQAGGLLPFLTVTENVEITQRIAQRPDESWLKALLGELGLSQIAHLRPGALSIGQRQR
VAIARALAHRPFCVIADEPTAALDPENAQVAMGLLIEAARAGGTATLLSSHDYPTLEKFEMRRMRLQITSAPHDPDVVST
LVAMNTQGATSPSDRVDV

Specific function: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-de

COG id: COG1136

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI46592956, Length=198, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI46592915, Length=198, Percent_Identity=29.7979797979798, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI46592898, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI46592978, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI46592971, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI46592964, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI215820660, Length=195, Percent_Identity=28.7179487179487, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI20143975, Length=195, Percent_Identity=28.7179487179487, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI11967969, Length=204, Percent_Identity=30.3921568627451, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI27477115, Length=188, Percent_Identity=29.2553191489362, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI87081834, Length=207, Percent_Identity=39.1304347826087, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786703, Length=212, Percent_Identity=35.377358490566, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787105, Length=227, Percent_Identity=33.0396475770925, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787029, Length=200, Percent_Identity=35.5, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788225, Length=165, Percent_Identity=36.969696969697, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790544, Length=207, Percent_Identity=34.7826086956522, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789672, Length=210, Percent_Identity=28.0952380952381, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786398, Length=194, Percent_Identity=30.9278350515464, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787089, Length=182, Percent_Identity=35.7142857142857, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786872, Length=176, Percent_Identity=32.3863636363636, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787758, Length=199, Percent_Identity=30.1507537688442, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789593, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI48994943, Length=191, Percent_Identity=27.2251308900524, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081791, Length=188, Percent_Identity=28.7234042553192, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787370, Length=188, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787164, Length=189, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789032, Length=162, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788761, Length=164, Percent_Identity=34.1463414634146, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788506, Length=200, Percent_Identity=31.5, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789963, Length=218, Percent_Identity=31.1926605504587, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787712, Length=218, Percent_Identity=24.7706422018349, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789873, Length=215, Percent_Identity=29.7674418604651, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786563, Length=188, Percent_Identity=33.5106382978723, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081782, Length=189, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786253, Length=214, Percent_Identity=26.6355140186916, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789891, Length=218, Percent_Identity=29.8165137614679, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=205, Percent_Identity=27.8048780487805, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28571871, Length=211, Percent_Identity=27.9620853080569, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574744, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015854
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27562; Mature: 27431

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSLAIDDLTVTLGDAERRFTLQAGQWSIAAGEVIGLTGPSGTGKTLLLELLGMLRAPD
CCEEEEECCEEEEECCCCEEEEEECCCEEEECCCEEEECCCCCCCHHHHHHHHHHHCCCC
RGSYIATPLAGTAGTRQEFHSFWQDANAMALCAGARAGFFGFVPQAGGLLPFLTVTENVE
CCCEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEECCCCCCCCEEEEEEECCHH
ITQRIAQRPDESWLKALLGELGLSQIAHLRPGALSIGQRQRVAIARALAHRPFCVIADEP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCC
TAALDPENAQVAMGLLIEAARAGGTATLLSSHDYPTLEKFEMRRMRLQITSAPHDPDVVS
CCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHEEEECCCCCHHHHH
TLVAMNTQGATSPSDRVDV
HHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AYSLAIDDLTVTLGDAERRFTLQAGQWSIAAGEVIGLTGPSGTGKTLLLELLGMLRAPD
CEEEEECCEEEEECCCCEEEEEECCCEEEECCCEEEECCCCCCCHHHHHHHHHHHCCCC
RGSYIATPLAGTAGTRQEFHSFWQDANAMALCAGARAGFFGFVPQAGGLLPFLTVTENVE
CCCEEECCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCEECCCCCCCCEEEEEEECCHH
ITQRIAQRPDESWLKALLGELGLSQIAHLRPGALSIGQRQRVAIARALAHRPFCVIADEP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCC
TAALDPENAQVAMGLLIEAARAGGTATLLSSHDYPTLEKFEMRRMRLQITSAPHDPDVVS
CCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHEEEECCCCCHHHHH
TLVAMNTQGATSPSDRVDV
HHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA