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The map label for this gene is rppH

Identifier: 110678307

GI number: 110678307

Start: 926427

End: 926909

Strand: Direct

Name: rppH

Synonym: RD1_0960

Alternate gene names: 110678307

Gene position: 926427-926909 (Clockwise)

Preceding gene: 110678305

Following gene: 110678311

Centisome position: 22.41

GC content: 56.52

Gene sequence:

>483_bases
ATGACCCCAGAAGAGATCGCCAGACTGCCCTATCGTCCTTGCGTGGGTGTGATGTTGATGAACGGACAGGGCGAGGTTTT
CGTAGGGCAGCGGCGCGATAACAACGTCGCCGCATGGCAGATGCCTCAGGGTGGGGTTGAAAAAGGTGAAGACCCGCGCG
CCGCCGCCTTGCGTGAATTATGGGAAGAAACAGGTGTGAACCCTGAATTGGCCGAGGTGGTGGCGGAGACGGAAGACTGG
CTGCCTTATGATCTGCCTTATGATCTGGTGCCAAAGCTGTGGAAAGGGCGATACCGTGGGCAAGAGCAGAAGTGGTTTCT
GATGCGCTTTCACGGGGCAGACAGCGATATCAACATCGCAACCGAACATCCGGAGTTCTCACAGTGGCGCTGGCTGCCTG
CGGCGGATTTGGTTGAGAATATCGTTCCCTTCAAGCGGGACGTTTACGTGGCCGTACTCGATGCTTTTGAGGCGCATCTT
TAG

Upstream 100 bases:

>100_bases
GGCCCGACCGGGCTTTTGTGCGATGGGTTTTTTGCGTATGCCTGACAAATCATTAAGCACACGAAAAAACAAAATGCGAC
CCAGCGGAAAAGGACCCGTC

Downstream 100 bases:

>100_bases
GGGTCAAAGATTGGAATATTCGCGCCTGCGGTTCTGGGCAGAATGCCAAGGATGCGCGGATCATCGTCTATTTCGACTTC
CTGGCGGACAGGGGTAAAAC

Product: hydrolase NUDIX family domain-containing protein

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTPEEIARLPYRPCVGVMLMNGQGEVFVGQRRDNNVAAWQMPQGGVEKGEDPRAAALRELWEETGVNPELAEVVAETEDW
LPYDLPYDLVPKLWKGRYRGQEQKWFLMRFHGADSDINIATEHPEFSQWRWLPAADLVENIVPFKRDVYVAVLDAFEAHL

Sequences:

>Translated_160_residues
MTPEEIARLPYRPCVGVMLMNGQGEVFVGQRRDNNVAAWQMPQGGVEKGEDPRAAALRELWEETGVNPELAEVVAETEDW
LPYDLPYDLVPKLWKGRYRGQEQKWFLMRFHGADSDINIATEHPEFSQWRWLPAADLVENIVPFKRDVYVAVLDAFEAHL
>Mature_159_residues
TPEEIARLPYRPCVGVMLMNGQGEVFVGQRRDNNVAAWQMPQGGVEKGEDPRAAALRELWEETGVNPELAEVVAETEDWL
PYDLPYDLVPKLWKGRYRGQEQKWFLMRFHGADSDINIATEHPEFSQWRWLPAADLVENIVPFKRDVYVAVLDAFEAHL

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=149, Percent_Identity=41.6107382550336, Blast_Score=113, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_ROSDO (Q16BL5)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_681314.1
- ProteinModelPortal:   Q16BL5
- SMR:   Q16BL5
- STRING:   Q16BL5
- GeneID:   4197744
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_0960
- eggNOG:   COG0494
- HOGENOM:   HBG302451
- OMA:   AGRAWKG
- PhylomeDB:   Q16BL5
- ProtClustDB:   CLSK759298
- BioCyc:   RDEN375451:RD1_0960-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 18439; Mature: 18308

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEEIARLPYRPCVGVMLMNGQGEVFVGQRRDNNVAAWQMPQGGVEKGEDPRAAALREL
CCHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
WEETGVNPELAEVVAETEDWLPYDLPYDLVPKLWKGRYRGQEQKWFLMRFHGADSDINIA
HHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEE
TEHPEFSQWRWLPAADLVENIVPFKRDVYVAVLDAFEAHL
ECCCCCCCEECCCHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPEEIARLPYRPCVGVMLMNGQGEVFVGQRRDNNVAAWQMPQGGVEKGEDPRAAALREL
CHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHH
WEETGVNPELAEVVAETEDWLPYDLPYDLVPKLWKGRYRGQEQKWFLMRFHGADSDINIA
HHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEE
TEHPEFSQWRWLPAADLVENIVPFKRDVYVAVLDAFEAHL
ECCCCCCCEECCCHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA