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The map label for this gene is phhB

Identifier: 110678291

GI number: 110678291

Start: 913906

End: 914202

Strand: Direct

Name: phhB

Synonym: RD1_0944

Alternate gene names: NA

Gene position: 913906-914202 (Clockwise)

Preceding gene: 110678290

Following gene: 110678292

Centisome position: 22.11

GC content: 53.2

Gene sequence:

>297_bases
ATGACAGAAAAGCTAAGCACCGAAACACGCGGCCCATTGCTGGAGCCGCTTTTCGCCTCAGGCTGGGAGATGGTCGAGGG
GCGGGACGCGATCAAAAAGACGTTTGTGTTCGACAATTTCGTCGATGCCTTTGGCTGGATGACACGCGTTGCGATCTGGG
CTGAAAAATGGAACCACCACCCAGAGTGGGACAATGTTTACAAAACGGTGAATGTGGTGCTGACCACGCATGATGTGGGT
GGGCTGAGCACATTGGATGCGAAACTGGCCCGTAAAATGGACAGTTTGGCAGGATAA

Upstream 100 bases:

>100_bases
TTGATCAATATCTGACGGCTGAACGCGAGGCCGTGGATCAGGAAATCAGCGTGCTGACCACCTATGGTCCCTTCAAGCGC
GCCAAAGTTGAGGAACAGGA

Downstream 100 bases:

>100_bases
CATAATATGCAGGCACTATTGCAAACAGAAGTATGGCAGGGAAAGACGGTCGCGGATTTGCTGTCGGTCGAATTCCTGAT
GTCTGCGGTCGGGTCCGTCG

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MTEKLSTETRGPLLEPLFASGWEMVEGRDAIKKTFVFDNFVDAFGWMTRVAIWAEKWNHHPEWDNVYKTVNVVLTTHDVG
GLSTLDAKLARKMDSLAG

Sequences:

>Translated_98_residues
MTEKLSTETRGPLLEPLFASGWEMVEGRDAIKKTFVFDNFVDAFGWMTRVAIWAEKWNHHPEWDNVYKTVNVVLTTHDVG
GLSTLDAKLARKMDSLAG
>Mature_97_residues
TEKLSTETRGPLLEPLFASGWEMVEGRDAIKKTFVFDNFVDAFGWMTRVAIWAEKWNHHPEWDNVYKTVNVVLTTHDVGG
LSTLDAKLARKMDSLAG

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI4557831, Length=94, Percent_Identity=53.1914893617021, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI134133240, Length=97, Percent_Identity=49.4845360824742, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115533705, Length=92, Percent_Identity=53.2608695652174, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI45549100, Length=98, Percent_Identity=51.0204081632653, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_ROSDO (Q16BN1)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_681298.1
- ProteinModelPortal:   Q16BN1
- SMR:   Q16BN1
- STRING:   Q16BN1
- GeneID:   4197728
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_0944
- NMPDR:   fig|375451.6.peg.886
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   SEERKTR
- ProtClustDB:   PRK00823
- BioCyc:   RDEN375451:RD1_0944-MONOMER
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11127; Mature: 10996

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKLSTETRGPLLEPLFASGWEMVEGRDAIKKTFVFDNFVDAFGWMTRVAIWAEKWNHH
CCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEWDNVYKTVNVVLTTHDVGGLSTLDAKLARKMDSLAG
CCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEKLSTETRGPLLEPLFASGWEMVEGRDAIKKTFVFDNFVDAFGWMTRVAIWAEKWNHH
CCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEWDNVYKTVNVVLTTHDVGGLSTLDAKLARKMDSLAG
CCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA