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The map label for this gene is siaT [H]

Identifier: 110678200

GI number: 110678200

Start: 826786

End: 828099

Strand: Direct

Name: siaT [H]

Synonym: RD1_0848

Alternate gene names: 110678200

Gene position: 826786-828099 (Clockwise)

Preceding gene: 110678199

Following gene: 110678202

Centisome position: 20.0

GC content: 57.53

Gene sequence:

>1314_bases
ATGGAAAACCTAGACCCGCTTGCGATTACCGGCATCATGTTTGCCTCGATGCTCGCGCTCATGGCGCTGGGCGCGCCACT
CGCCTGGGCACTGACGATCTGCGGGATTGGCAGTGCATACGCGATTTACGGCGATGGGGGGCTCGACCTTCTGATCACCT
CTACCTTCAGCGCCATGGACAACTTTTTGCTGGTGGCCCTGCCGCTATTCATCTTCATGGGGCTGGTGCTGCAGCGGTCC
GGTATCACCGACGATCTGTTTGACATGATGCACAAGCTGATGGGGCGACTGCCCGGTGGCCTCGGCATCGGCACGGTGAT
CATCTGTGCCCTGATCGCCGCAATGGCGGGTGTTTCTGGCGCCGCGACGGTCAGTCTTGGGATCATCGCCCTGCCCGCGA
TGTTGAGCCGTGGATATGACAAGCGCCTTGTAACCGGGACCATCATGGCGGGTGGCGCGCTCGGTTTCCTGATCCCGCCC
AGCGTGCTGATGATCATCTATGCGTTTTTGAGCCGCGACTCCGTGGGCAAGCTCTTTGCCGCAGGGTTGATGCCGGGCCT
GATGCTGGCTGGTATCTACATCGCCTACATCCTGATCCGGTGTCGTCTGAACCCGCAGCTTGGCCCCCCCGCCGAAGAGC
AGTTCACCACCGCCGAAAAGGTCAAATCACTACGCTTTCTTATCGCGCCGGGTTTGCTCATTGTGAGTGTTCTGGGCTGT
ATCATCGGAGGCATTACGTCACCCTCCGAAGCTTCGGCCATTGGGGCTTTCGGCGCGCTTGTCATCGCGGCAATTCAGCG
TCGTCTGAGTTGGGATTTGATGCGCTATGTCATGCTCTCCACCACCAAGCTGATGGGCATGCTGATGTGGATCACCATCG
CTGCCGTGTTCTTTTCCAAGATCTACGTCGGCGTGGGTGCGGGGGTCGTTGTGGGCGAGTTGATCGAAGATTACGAGTTG
TCGCCGAACTATGTGATCCTTGCGATGCTGCTGGCCTATTTTGTCCTCGGCATGTTTCTCGACGATTTCGCGATCGTCTT
CATTACCGTGCCGTTGTTTGTGCCAATCGTGCGGGATCTTGGGTTTGATACGACGTGGTTCGCGGTTCTCTTTATCCTGA
GCATGCAGTCGGCCTATCTGACGCCGCCGTTTGGCTACAACCTCTTTTACATGAGGTCGGTGGCCCCCAAGAGCATTACG
ATCATAGATATCTATTGGGCGGCGATCCCGTTTGTCGCATTACAGATCCTTGGACTTGCGCTGGTGTTCACCTTCCCGCA
GATTGCGCTCTGGTTGCCAAGCCTGCTGTTCTGA

Upstream 100 bases:

>100_bases
TCGCGCAAGAGCTACTTGGGGCTGACAGCAATAAATCCTAGGCGCGGCAGGCGCTGATCCAGCATTTTTCAAGCGCCACG
TCCTTTCAAGGAACACCACT

Downstream 100 bases:

>100_bases
CGGCCTGTCCTTGGCGCCCTATTTGAACGAGGCCCCGTCGACCGGATCGGTTTCCAGCGCGCTGACAGCATCGATGTCAT
TTCGCACCCAGAAAAAGCGG

Product: TRAP dicarboxylate transporter, DctM subunit, putative

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MENLDPLAITGIMFASMLALMALGAPLAWALTICGIGSAYAIYGDGGLDLLITSTFSAMDNFLLVALPLFIFMGLVLQRS
GITDDLFDMMHKLMGRLPGGLGIGTVIICALIAAMAGVSGAATVSLGIIALPAMLSRGYDKRLVTGTIMAGGALGFLIPP
SVLMIIYAFLSRDSVGKLFAAGLMPGLMLAGIYIAYILIRCRLNPQLGPPAEEQFTTAEKVKSLRFLIAPGLLIVSVLGC
IIGGITSPSEASAIGAFGALVIAAIQRRLSWDLMRYVMLSTTKLMGMLMWITIAAVFFSKIYVGVGAGVVVGELIEDYEL
SPNYVILAMLLAYFVLGMFLDDFAIVFITVPLFVPIVRDLGFDTTWFAVLFILSMQSAYLTPPFGYNLFYMRSVAPKSIT
IIDIYWAAIPFVALQILGLALVFTFPQIALWLPSLLF

Sequences:

>Translated_437_residues
MENLDPLAITGIMFASMLALMALGAPLAWALTICGIGSAYAIYGDGGLDLLITSTFSAMDNFLLVALPLFIFMGLVLQRS
GITDDLFDMMHKLMGRLPGGLGIGTVIICALIAAMAGVSGAATVSLGIIALPAMLSRGYDKRLVTGTIMAGGALGFLIPP
SVLMIIYAFLSRDSVGKLFAAGLMPGLMLAGIYIAYILIRCRLNPQLGPPAEEQFTTAEKVKSLRFLIAPGLLIVSVLGC
IIGGITSPSEASAIGAFGALVIAAIQRRLSWDLMRYVMLSTTKLMGMLMWITIAAVFFSKIYVGVGAGVVVGELIEDYEL
SPNYVILAMLLAYFVLGMFLDDFAIVFITVPLFVPIVRDLGFDTTWFAVLFILSMQSAYLTPPFGYNLFYMRSVAPKSIT
IIDIYWAAIPFVALQILGLALVFTFPQIALWLPSLLF
>Mature_437_residues
MENLDPLAITGIMFASMLALMALGAPLAWALTICGIGSAYAIYGDGGLDLLITSTFSAMDNFLLVALPLFIFMGLVLQRS
GITDDLFDMMHKLMGRLPGGLGIGTVIICALIAAMAGVSGAATVSLGIIALPAMLSRGYDKRLVTGTIMAGGALGFLIPP
SVLMIIYAFLSRDSVGKLFAAGLMPGLMLAGIYIAYILIRCRLNPQLGPPAEEQFTTAEKVKSLRFLIAPGLLIVSVLGC
IIGGITSPSEASAIGAFGALVIAAIQRRLSWDLMRYVMLSTTKLMGMLMWITIAAVFFSKIYVGVGAGVVVGELIEDYEL
SPNYVILAMLLAYFVLGMFLDDFAIVFITVPLFVPIVRDLGFDTTWFAVLFILSMQSAYLTPPFGYNLFYMRSVAPKSIT
IIDIYWAAIPFVALQILGLALVFTFPQIALWLPSLLF

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=387, Percent_Identity=29.1989664082687, Blast_Score=138, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46891; Mature: 46891

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]