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The map label for this gene is mtnU [H]

Identifier: 110678202

GI number: 110678202

Start: 828643

End: 829530

Strand: Direct

Name: mtnU [H]

Synonym: RD1_0850

Alternate gene names: 110678202

Gene position: 828643-829530 (Clockwise)

Preceding gene: 110678200

Following gene: 110678203

Centisome position: 20.05

GC content: 56.98

Gene sequence:

>888_bases
ATGACCCACTTCAACGTAGCCGGCATTCAGATGCATATCGGCATGAAAAGCAATCTCGAGGAGATGAACCGTCGTCTCGA
TCTTTTGATGCACCTCTATCCATGGGTAGAGATGGTGGTCTTTAGCGAACTGGCCGCCAATGGACCCAACCCCGCATCGG
CCCAGCCCATGGGTGGCGAGAACGAGCAGGCCTTTGCGAAAATGGCGCAGAAACACAACATCTGGCTCATCCCCGGGGGT
ATGTTCGAAAAGAAAGACGGCCGCATCTATAACATGACGCCGGTGCTCAATCCCGAAGGCGAGATCGTCACGCGCTATCG
CAAGATGTTTCCGTTCACACCTTATGAGGACGCAACGGAGCCGGGTGACGAATTCTGCGTATTCGACGTGCCCGGCGTTG
GCCGGTTCGGTGTCGCGATCTGCTATGATCTGTGGTTCCCCGAAGTCATGCGGACCCTGACATCTATGGGAGCCGAGGTG
ATCATCAACCCCGTTCTGGCGCATTTCGTCGACCGCCCTGCAGACCTGGCCATCGCGCAGGCCTCCGCTGCGATGTTCCA
GAGCTATGTTTTTCATATCAACGGCTTGCTGGCAGGTGGGAACGGGTATTCCCGCGTCGTCGATCCGGCGGGCCAGTTGC
TGCATGATGGCAACGTCCAGGAGGAACTCATCCCGATTGAGGTCGATTTCGACCTTGTACGCCGCCAGCGTGAACGCGGG
TTGCTCGGTATGGGACAGGTCCTCAAGAGTTTCCGTGATCGCAAGGTGAACTTCGATGTCTATTCGGAACACTTCGATCA
CAGCTACCTGAACAGTCTGGGCGTTCTCGTCAAACCGGAGCGACCGCAACGCGCGGCGCCTCAGGGGAATACCCAGCCTA
AGACTTAA

Upstream 100 bases:

>100_bases
GAATCATAGTGATGTCTAGGCTTGTTCGAAAGTCACTTTCTGCGCGCCCCGTACCGTGTCGCGGCAAGTCAAGACGTCAT
GCCCTAAGCAAAGGTTGCCC

Downstream 100 bases:

>100_bases
AAAGATCGGTCACAGACCGGCAAGCGAAACAGGGAAAGCCCATAAATTGTTTAACGGCTGTCCAAGATGGCCAGATCATA
AGGGAAAGACCAAATGACCA

Product: hydrolase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTHFNVAGIQMHIGMKSNLEEMNRRLDLLMHLYPWVEMVVFSELAANGPNPASAQPMGGENEQAFAKMAQKHNIWLIPGG
MFEKKDGRIYNMTPVLNPEGEIVTRYRKMFPFTPYEDATEPGDEFCVFDVPGVGRFGVAICYDLWFPEVMRTLTSMGAEV
IINPVLAHFVDRPADLAIAQASAAMFQSYVFHINGLLAGGNGYSRVVDPAGQLLHDGNVQEELIPIEVDFDLVRRQRERG
LLGMGQVLKSFRDRKVNFDVYSEHFDHSYLNSLGVLVKPERPQRAAPQGNTQPKT

Sequences:

>Translated_295_residues
MTHFNVAGIQMHIGMKSNLEEMNRRLDLLMHLYPWVEMVVFSELAANGPNPASAQPMGGENEQAFAKMAQKHNIWLIPGG
MFEKKDGRIYNMTPVLNPEGEIVTRYRKMFPFTPYEDATEPGDEFCVFDVPGVGRFGVAICYDLWFPEVMRTLTSMGAEV
IINPVLAHFVDRPADLAIAQASAAMFQSYVFHINGLLAGGNGYSRVVDPAGQLLHDGNVQEELIPIEVDFDLVRRQRERG
LLGMGQVLKSFRDRKVNFDVYSEHFDHSYLNSLGVLVKPERPQRAAPQGNTQPKT
>Mature_294_residues
THFNVAGIQMHIGMKSNLEEMNRRLDLLMHLYPWVEMVVFSELAANGPNPASAQPMGGENEQAFAKMAQKHNIWLIPGGM
FEKKDGRIYNMTPVLNPEGEIVTRYRKMFPFTPYEDATEPGDEFCVFDVPGVGRFGVAICYDLWFPEVMRTLTSMGAEVI
INPVLAHFVDRPADLAIAQASAAMFQSYVFHINGLLAGGNGYSRVVDPAGQLLHDGNVQEELIPIEVDFDLVRRQRERGL
LGMGQVLKSFRDRKVNFDVYSEHFDHSYLNSLGVLVKPERPQRAAPQGNTQPKT

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=261, Percent_Identity=27.2030651340996, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI297632348, Length=210, Percent_Identity=28.0952380952381, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI297632350, Length=210, Percent_Identity=28.0952380952381, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031947, Length=207, Percent_Identity=27.0531400966184, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323383, Length=218, Percent_Identity=28.8990825688073, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355835, Length=198, Percent_Identity=26.2626262626263, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17933642, Length=228, Percent_Identity=28.0701754385965, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: NA

Molecular weight: Translated: 33158; Mature: 33027

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHFNVAGIQMHIGMKSNLEEMNRRLDLLMHLYPWVEMVVFSELAANGPNPASAQPMGGE
CCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NEQAFAKMAQKHNIWLIPGGMFEKKDGRIYNMTPVLNPEGEIVTRYRKMFPFTPYEDATE
CHHHHHHHHHHCCEEEECCCCEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCC
PGDEFCVFDVPGVGRFGVAICYDLWFPEVMRTLTSMGAEVIINPVLAHFVDRPADLAIAQ
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH
ASAAMFQSYVFHINGLLAGGNGYSRVVDPAGQLLHDGNVQEELIPIEVDFDLVRRQRERG
HHHHHHHHHHHHHHCEEECCCCCCHHHCHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCC
LLGMGQVLKSFRDRKVNFDVYSEHFDHSYLNSLGVLVKPERPQRAAPQGNTQPKT
CHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THFNVAGIQMHIGMKSNLEEMNRRLDLLMHLYPWVEMVVFSELAANGPNPASAQPMGGE
CCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NEQAFAKMAQKHNIWLIPGGMFEKKDGRIYNMTPVLNPEGEIVTRYRKMFPFTPYEDATE
CHHHHHHHHHHCCEEEECCCCEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCC
PGDEFCVFDVPGVGRFGVAICYDLWFPEVMRTLTSMGAEVIINPVLAHFVDRPADLAIAQ
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH
ASAAMFQSYVFHINGLLAGGNGYSRVVDPAGQLLHDGNVQEELIPIEVDFDLVRRQRERG
HHHHHHHHHHHHHHCEEECCCCCCHHHCHHHHHHCCCCCCCCEEEEEECHHHHHHHHHCC
LLGMGQVLKSFRDRKVNFDVYSEHFDHSYLNSLGVLVKPERPQRAAPQGNTQPKT
CHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHCCEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]