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The map label for this gene is pncB [H]

Identifier: 110677967

GI number: 110677967

Start: 568444

End: 569736

Strand: Direct

Name: pncB [H]

Synonym: RD1_0586

Alternate gene names: 110677967

Gene position: 568444-569736 (Clockwise)

Preceding gene: 110677966

Following gene: 110677968

Centisome position: 13.75

GC content: 56.69

Gene sequence:

>1293_bases
ATGGTTGATATCGCAACCCGCGTCTGGAACCACAAATGGAAGATCGACCCGATTGTGCGCTCGTTGATCGATACGGATTT
TTACAAGCTTCTGATGTGTCAGTCGGTTTTCCGTAACAAACCCGATACGCGCGTGACCTTCAGTCTGATCAACAGGTCCA
CCCATATCCCGCTTGCCGAACTCATTGACGAGGGGGAGCTGCGCGAACAGCTGGATCATATCCGCTCGCTTTCCTTGTCG
CGCGGAGAAAGCACATGGCTGCGCGGCAATACCTTTTACGGCAAACGGCAGATGTTTCGTTCGGATTTCATGGAGTGGTT
CGAACAGCTTCGCCTGCCAGCCTATCACCTTGAACGGATAGGCGATCAGTTTGAGCTGACATTTGAAGGCAGCTGGCCGG
AAGTCATGCTTTGGGAGATACCGGCGCTCGCCGTTCTCATGGAATTGCGCGGGCGCGCGGTGCTCGACCAGATGGACAGG
TTCGAGTTGCAAGTGCTGTACGCGCGCGCGATGACGCGGGTGTGGGAAAAGGTCGAGGCCCTGCGCGACATCCCTGATTT
GTCGATTGCGGATTTCGGCACGCGCCGACGTCACAGCTTTCTTTGGCAGGACTGGTGCGTTCAGGCGATGCGCGAGGGGC
TTGGTGCTGCCTTCACGGGCACGTCGAACTGCAAGATTGCGATGACCCGCGAGATGGAAGCCATTGGGACAAATGCGCAT
GAATTGCCGATGGTTTACGCAGCACTGGCACGCGATGACGCGGCATTGGCGCAAGCACCATATGACGTTCTGTCAGACTG
GCATGACGAGCATGAAGGCAACCTGCGCATCATTCTGCCCGACACTTTCGGCACCAGCAGATTCCTTGAAAAAGCGCCGG
ACTGGCTTGCGGGTTGGACAGGCATCAGAATAGACAGTGGCGATCCGGTGCAAGCGGGTGAAAACGCAATCGACTGGTGG
CGCTCAAGAGGCGAAGATCCGAGCAAGAAGCGCGTTATTTTCAGCGACGGGCTGGATGTGGACAAGATCCGCAGCCTGCA
TCGCACGTTTTCCGGGCGGGTGCAGCCGTCCTTTGGTTGGGGAACCCTGCTGACGAACGATTTTCGCAATCTGGTACCAC
ATGACAGCCTCGCACCGTTCTCTCTGGTCTGCAAAGCGGTTAAAGCCAACGGGCGGCCCACAGTCAAACTCTCCGATAAC
CCGAACAAGGCGATGGGGCCGGCCGCTGAGATCGAACGATATAAACGTGTGTTTGATGTCGGGGTGCAACGCGCGCAAGA
CGTTGTTGTTTAA

Upstream 100 bases:

>100_bases
ACAGTACGCGAAGATCTGTGCCGCGCGATTGACCTTGATGGTTCCCGTGATGCAGCGCGTCAGGCCATGCAGAATGCGGG
CGTGCGTCTGGAGACAGTGC

Downstream 100 bases:

>100_bases
GCAACTTTTCTAATAGCTTGAGGTATCCAGACCGCAGCAGTTTCATTCGATACTGTCAGGCAGTTGGTTCATCTGATCTG
GCATGCCCATAACACTGTTT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTRVTFSLINRSTHIPLAELIDEGELREQLDHIRSLSLS
RGESTWLRGNTFYGKRQMFRSDFMEWFEQLRLPAYHLERIGDQFELTFEGSWPEVMLWEIPALAVLMELRGRAVLDQMDR
FELQVLYARAMTRVWEKVEALRDIPDLSIADFGTRRRHSFLWQDWCVQAMREGLGAAFTGTSNCKIAMTREMEAIGTNAH
ELPMVYAALARDDAALAQAPYDVLSDWHDEHEGNLRIILPDTFGTSRFLEKAPDWLAGWTGIRIDSGDPVQAGENAIDWW
RSRGEDPSKKRVIFSDGLDVDKIRSLHRTFSGRVQPSFGWGTLLTNDFRNLVPHDSLAPFSLVCKAVKANGRPTVKLSDN
PNKAMGPAAEIERYKRVFDVGVQRAQDVVV

Sequences:

>Translated_430_residues
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTRVTFSLINRSTHIPLAELIDEGELREQLDHIRSLSLS
RGESTWLRGNTFYGKRQMFRSDFMEWFEQLRLPAYHLERIGDQFELTFEGSWPEVMLWEIPALAVLMELRGRAVLDQMDR
FELQVLYARAMTRVWEKVEALRDIPDLSIADFGTRRRHSFLWQDWCVQAMREGLGAAFTGTSNCKIAMTREMEAIGTNAH
ELPMVYAALARDDAALAQAPYDVLSDWHDEHEGNLRIILPDTFGTSRFLEKAPDWLAGWTGIRIDSGDPVQAGENAIDWW
RSRGEDPSKKRVIFSDGLDVDKIRSLHRTFSGRVQPSFGWGTLLTNDFRNLVPHDSLAPFSLVCKAVKANGRPTVKLSDN
PNKAMGPAAEIERYKRVFDVGVQRAQDVVV
>Mature_430_residues
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTRVTFSLINRSTHIPLAELIDEGELREQLDHIRSLSLS
RGESTWLRGNTFYGKRQMFRSDFMEWFEQLRLPAYHLERIGDQFELTFEGSWPEVMLWEIPALAVLMELRGRAVLDQMDR
FELQVLYARAMTRVWEKVEALRDIPDLSIADFGTRRRHSFLWQDWCVQAMREGLGAAFTGTSNCKIAMTREMEAIGTNAH
ELPMVYAALARDDAALAQAPYDVLSDWHDEHEGNLRIILPDTFGTSRFLEKAPDWLAGWTGIRIDSGDPVQAGENAIDWW
RSRGEDPSKKRVIFSDGLDVDKIRSLHRTFSGRVQPSFGWGTLLTNDFRNLVPHDSLAPFSLVCKAVKANGRPTVKLSDN
PNKAMGPAAEIERYKRVFDVGVQRAQDVVV

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=414, Percent_Identity=33.5748792270531, Blast_Score=192, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6324783, Length=421, Percent_Identity=30.166270783848, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 49416; Mature: 49416

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTRVTFSLINRSTHIPLAE
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCHHH
LIDEGELREQLDHIRSLSLSRGESTWLRGNTFYGKRQMFRSDFMEWFEQLRLPAYHLERI
HHCCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHC
GDQFELTFEGSWPEVMLWEIPALAVLMELRGRAVLDQMDRFELQVLYARAMTRVWEKVEA
CCCEEEEECCCCCCEEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRDIPDLSIADFGTRRRHSFLWQDWCVQAMREGLGAAFTGTSNCKIAMTREMEAIGTNAH
HHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECHHHHHCCCCH
ELPMVYAALARDDAALAQAPYDVLSDWHDEHEGNLRIILPDTFGTSRFLEKAPDWLAGWT
HHHHHHHHHHCCCHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCHHHHCCC
GIRIDSGDPVQAGENAIDWWRSRGEDPSKKRVIFSDGLDVDKIRSLHRTFSGRVQPSFGW
EEEECCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCC
GTLLTNDFRNLVPHDSLAPFSLVCKAVKANGRPTVKLSDNPNKAMGPAAEIERYKRVFDV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
GVQRAQDVVV
HHHHHHHCCC
>Mature Secondary Structure
MVDIATRVWNHKWKIDPIVRSLIDTDFYKLLMCQSVFRNKPDTRVTFSLINRSTHIPLAE
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCHHH
LIDEGELREQLDHIRSLSLSRGESTWLRGNTFYGKRQMFRSDFMEWFEQLRLPAYHLERI
HHCCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHC
GDQFELTFEGSWPEVMLWEIPALAVLMELRGRAVLDQMDRFELQVLYARAMTRVWEKVEA
CCCEEEEECCCCCCEEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRDIPDLSIADFGTRRRHSFLWQDWCVQAMREGLGAAFTGTSNCKIAMTREMEAIGTNAH
HHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECHHHHHCCCCH
ELPMVYAALARDDAALAQAPYDVLSDWHDEHEGNLRIILPDTFGTSRFLEKAPDWLAGWT
HHHHHHHHHHCCCHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCHHHHCCC
GIRIDSGDPVQAGENAIDWWRSRGEDPSKKRVIFSDGLDVDKIRSLHRTFSGRVQPSFGW
EEEECCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCC
GTLLTNDFRNLVPHDSLAPFSLVCKAVKANGRPTVKLSDNPNKAMGPAAEIERYKRVFDV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
GVQRAQDVVV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA