Click here to switch to the map view.

The map label for this gene is ilvE [H]

Identifier: 110677937

GI number: 110677937

Start: 536900

End: 537769

Strand: Direct

Name: ilvE [H]

Synonym: RD1_0553

Alternate gene names: 110677937

Gene position: 536900-537769 (Clockwise)

Preceding gene: 110677931

Following gene: 110677938

Centisome position: 12.99

GC content: 56.55

Gene sequence:

>870_bases
ATGGCCGGTGCCTATAATGATCGTGATGGACATATCTGGATGGATGGCCAGATGGTAGATTGGCGCGATGCAAATGTGCA
TATTCTGACCCATGCCATGCATTACGCGTCCTCCGTTTTCGAAGGGGAGCGGGCCTACAACGGCAAGATTTTCAAAAGCC
GCGAACATTCGGAGCGTCTTAAACGGTCTGCTCAGATGATTGATTTTGAAATTCCTTATACCGTTGACGAGATCGAAGCC
GCCAAGGTCGAGGTGCTGGAAAAATCCGGGTTGCAGGACGCCTATGTGCGCGCCATCGCATGGCGCGGCGCCGGCGAGGA
CATGGGGGTCGCTTCGGCGCGTAACCCGGTCAGGCTCGCGATTGCGGCATGGGAATGGGGTGCCTATTACGGCGACGCCA
AGATGAAGGGTGCAAAGCTGGACATCTCCAAATGGAAACGCCCCAGCCCTGAAACCATTCCAAGCCATGCCAAGGCGGCC
GGTCTTTACATGATCTGCACCATGTCGAAACACGCGGCAGAGGCCAAGGGATGTTCGGACGCCATGATGTTTGACTATCG
TGGCTATGTGGCCGAGGCGACGGGAGCCAACGTCTTTTTCGTGAAGGACGGCGAAGTACACACCCCTGACCCTGACTGTT
TCCTGAACGGGATCACACGGCAGACAGTGATCGGGATGCTGCGCGAGAAGCAGATCAAGGTGCATGAACGCCACATCATG
CCAGAGGAACTTGAAGGGTTTGAGCAATGCTGGCTGACGGGCACAGCCGCCGAAGTCACGCCCGTGGGTCAGATTGGCGA
TTACAATTTCGAGGTCGGCAACCTGACCCGTGACATCGCGCAAAGCTACGAAACCCTCGTTCGGGCCTGA

Upstream 100 bases:

>100_bases
AGGGATATCGAATCGCAGGTTTTGCGCAATTTTATGTCCGATGCGGACCAATCGGCGCAACTTATGAAAAATGCGATGGG
GAATCAGGGAAGGAAAAACC

Downstream 100 bases:

>100_bases
CCGAATGGACTACGCGGCCTTCGCTGTTGAATGGGAGGCCGCGTGGAATTCTCATGCCATCGACCGGATCATGGCGCATT
ATGCGCTCGATGTTGTGTTT

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MAGAYNDRDGHIWMDGQMVDWRDANVHILTHAMHYASSVFEGERAYNGKIFKSREHSERLKRSAQMIDFEIPYTVDEIEA
AKVEVLEKSGLQDAYVRAIAWRGAGEDMGVASARNPVRLAIAAWEWGAYYGDAKMKGAKLDISKWKRPSPETIPSHAKAA
GLYMICTMSKHAAEAKGCSDAMMFDYRGYVAEATGANVFFVKDGEVHTPDPDCFLNGITRQTVIGMLREKQIKVHERHIM
PEELEGFEQCWLTGTAAEVTPVGQIGDYNFEVGNLTRDIAQSYETLVRA

Sequences:

>Translated_289_residues
MAGAYNDRDGHIWMDGQMVDWRDANVHILTHAMHYASSVFEGERAYNGKIFKSREHSERLKRSAQMIDFEIPYTVDEIEA
AKVEVLEKSGLQDAYVRAIAWRGAGEDMGVASARNPVRLAIAAWEWGAYYGDAKMKGAKLDISKWKRPSPETIPSHAKAA
GLYMICTMSKHAAEAKGCSDAMMFDYRGYVAEATGANVFFVKDGEVHTPDPDCFLNGITRQTVIGMLREKQIKVHERHIM
PEELEGFEQCWLTGTAAEVTPVGQIGDYNFEVGNLTRDIAQSYETLVRA
>Mature_288_residues
AGAYNDRDGHIWMDGQMVDWRDANVHILTHAMHYASSVFEGERAYNGKIFKSREHSERLKRSAQMIDFEIPYTVDEIEAA
KVEVLEKSGLQDAYVRAIAWRGAGEDMGVASARNPVRLAIAAWEWGAYYGDAKMKGAKLDISKWKRPSPETIPSHAKAAG
LYMICTMSKHAAEAKGCSDAMMFDYRGYVAEATGANVFFVKDGEVHTPDPDCFLNGITRQTVIGMLREKQIKVHERHIMP
EELEGFEQCWLTGTAAEVTPVGQIGDYNFEVGNLTRDIAQSYETLVRA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=290, Percent_Identity=36.551724137931, Blast_Score=183, Evalue=1e-47,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 32364; Mature: 32233

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGAYNDRDGHIWMDGQMVDWRDANVHILTHAMHYASSVFEGERAYNGKIFKSREHSERL
CCCCCCCCCCEEEECCEEECCCCCCEEEEHHHHHHHHHHHCCCHHCCCCEEECCHHHHHH
KRSAQMIDFEIPYTVDEIEAAKVEVLEKSGLQDAYVRAIAWRGAGEDMGVASARNPVRLA
HHHHHEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCCCCCCEEEE
IAAWEWGAYYGDAKMKGAKLDISKWKRPSPETIPSHAKAAGLYMICTMSKHAAEAKGCSD
EEEEECCCEECCCCCCCCEEEHHHCCCCCCCCCCCCHHHCCEEEEEECCHHHHHHCCCCC
AMMFDYRGYVAEATGANVFFVKDGEVHTPDPDCFLNGITRQTVIGMLREKQIKVHERHIM
CEEEECCCEEEECCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
PEELEGFEQCWLTGTAAEVTPVGQIGDYNFEVGNLTRDIAQSYETLVRA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGAYNDRDGHIWMDGQMVDWRDANVHILTHAMHYASSVFEGERAYNGKIFKSREHSERL
CCCCCCCCCEEEECCEEECCCCCCEEEEHHHHHHHHHHHCCCHHCCCCEEECCHHHHHH
KRSAQMIDFEIPYTVDEIEAAKVEVLEKSGLQDAYVRAIAWRGAGEDMGVASARNPVRLA
HHHHHEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCCCCCCEEEE
IAAWEWGAYYGDAKMKGAKLDISKWKRPSPETIPSHAKAAGLYMICTMSKHAAEAKGCSD
EEEEECCCEECCCCCCCCEEEHHHCCCCCCCCCCCCHHHCCEEEEEECCHHHHHHCCCCC
AMMFDYRGYVAEATGANVFFVKDGEVHTPDPDCFLNGITRQTVIGMLREKQIKVHERHIM
CEEEECCCEEEECCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
PEELEGFEQCWLTGTAAEVTPVGQIGDYNFEVGNLTRDIAQSYETLVRA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]