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The map label for this gene is asd [H]

Identifier: 110677709

GI number: 110677709

Start: 295514

End: 296536

Strand: Direct

Name: asd [H]

Synonym: RD1_0306

Alternate gene names: 110677709

Gene position: 295514-296536 (Clockwise)

Preceding gene: 110677707

Following gene: 110677716

Centisome position: 7.15

GC content: 55.82

Gene sequence:

>1023_bases
ATGGGTTACCGCGTCGTTGTTGCGGGTGCCACAGGCAATGTGGGCCGCGAAATGCTGAACATTCTTGCTGAACGCCACTT
TCCGGTGGATGACATTACCGTGCTTGCATCACGCAAATCCCTGGGCACCGAAGTCAGTTTTGGCGACAAAACGCTCAAGA
CGAAGGATCTTGCGACATTCGATTTCACGGGCTGGGACATGGCGCTTTTCGCAATCGGTTCGGATGCGACAAAGGAATTT
GCACCCAAGGCGGCCAAAGCCGGCTGTGTCGTGATTGATAACTCGTCGCTTTACCGGTACGATGCGGATGTGCCGTTGAT
CGTGCCCGAGGTGAACGCCGATGCGATCATGGACTATGCCAACAAGAACATCATCGCCAACCCGAACTGTTCGACTGCGC
AAATGGTGGTGGCTCTGAAGCCACTGCATGACCGCGCGACCATAAAACGCGTTGTTGTCTCGACCTATCAGTCGGTTTCA
GGCGCGGGCAAGGAAGGCGCGGATGAACTTTGGGACCAGACCAAATCCATCTACAATCCGACCGATGACAAGCCGCCGAA
GAAATTCACCAAGCAGATCGCATTCAACGTGATCCCGCATATTGATGTGTTCATGGAAGACGGCACCACCAAGGAAGAGT
GGAAAATGGTCGTTGAAACCAAGAAGATCATCGACACCAAGATCAAGGTCACCGCAACCTGCGTGCGCGTGCCCGTGTTC
GTGGGCCACTGCGAAGCGATCAATATCGAGTTCGAAGAGCACCTTGACGAGGACGAGGCCCGCGAAATCCTGCGCGAAGC
ACCGGGCGTCATGGTGATCGATAAACGCGAGGACGGCGGCTATGTGACGCCCGTCGAGTGCGTCGGTGATTTTGCGACAT
TCATCAGCCGTATCCGTCAGGATTCAACGATTGATAACGGTCTGAACCTGTGGTGCGTGTCCGACAACCTGCGCAAGGGC
GCGGCGCTCAACGCGGTGCAGATCGCGGAACTGCTGGGCACTCGGGTCCTGAAAAAGGGCTGA

Upstream 100 bases:

>100_bases
CTCTATGCCGCAGCCCGCACAGGCATGACGGCCCTTTCCTCAAGAGGCTGACCGGTATAAGACGCGCGCACCATCACATC
AAACACATTGGAGTATTTAG

Downstream 100 bases:

>100_bases
TTGACCCAAGGCATTTGGAAAACCGTCGGGTCACACCGGCGGCTTTTTTGCCAACGGCGGCCCAGCACACCGGATCAAAG
CCCCGGAATGCACCCCGGAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MGYRVVVAGATGNVGREMLNILAERHFPVDDITVLASRKSLGTEVSFGDKTLKTKDLATFDFTGWDMALFAIGSDATKEF
APKAAKAGCVVIDNSSLYRYDADVPLIVPEVNADAIMDYANKNIIANPNCSTAQMVVALKPLHDRATIKRVVVSTYQSVS
GAGKEGADELWDQTKSIYNPTDDKPPKKFTKQIAFNVIPHIDVFMEDGTTKEEWKMVVETKKIIDTKIKVTATCVRVPVF
VGHCEAINIEFEEHLDEDEAREILREAPGVMVIDKREDGGYVTPVECVGDFATFISRIRQDSTIDNGLNLWCVSDNLRKG
AALNAVQIAELLGTRVLKKG

Sequences:

>Translated_340_residues
MGYRVVVAGATGNVGREMLNILAERHFPVDDITVLASRKSLGTEVSFGDKTLKTKDLATFDFTGWDMALFAIGSDATKEF
APKAAKAGCVVIDNSSLYRYDADVPLIVPEVNADAIMDYANKNIIANPNCSTAQMVVALKPLHDRATIKRVVVSTYQSVS
GAGKEGADELWDQTKSIYNPTDDKPPKKFTKQIAFNVIPHIDVFMEDGTTKEEWKMVVETKKIIDTKIKVTATCVRVPVF
VGHCEAINIEFEEHLDEDEAREILREAPGVMVIDKREDGGYVTPVECVGDFATFISRIRQDSTIDNGLNLWCVSDNLRKG
AALNAVQIAELLGTRVLKKG
>Mature_339_residues
GYRVVVAGATGNVGREMLNILAERHFPVDDITVLASRKSLGTEVSFGDKTLKTKDLATFDFTGWDMALFAIGSDATKEFA
PKAAKAGCVVIDNSSLYRYDADVPLIVPEVNADAIMDYANKNIIANPNCSTAQMVVALKPLHDRATIKRVVVSTYQSVSG
AGKEGADELWDQTKSIYNPTDDKPPKKFTKQIAFNVIPHIDVFMEDGTTKEEWKMVVETKKIIDTKIKVTATCVRVPVFV
GHCEAINIEFEEHLDEDEAREILREAPGVMVIDKREDGGYVTPVECVGDFATFISRIRQDSTIDNGLNLWCVSDNLRKGA
ALNAVQIAELLGTRVLKKG

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=335, Percent_Identity=37.6119402985075, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=29.1316526610644, Blast_Score=104, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6320362, Length=393, Percent_Identity=27.735368956743, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37391; Mature: 37260

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYRVVVAGATGNVGREMLNILAERHFPVDDITVLASRKSLGTEVSFGDKTLKTKDLATF
CCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCHHCCCEECCCCCCCCCCCCEEE
DFTGWDMALFAIGSDATKEFAPKAAKAGCVVIDNSSLYRYDADVPLIVPEVNADAIMDYA
ECCCCCEEEEEECCCHHHHHCCHHHCCCEEEEECCCEEEECCCCCEEEECCCHHHHHHHC
NKNIIANPNCSTAQMVVALKPLHDRATIKRVVVSTYQSVSGAGKEGADELWDQTKSIYNP
CCCEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
TDDKPPKKFTKQIAFNVIPHIDVFMEDGTTKEEWKMVVETKKIIDTKIKVTATCVRVPVF
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCEEEEEEEEEEEEEE
VGHCEAINIEFEEHLDEDEAREILREAPGVMVIDKREDGGYVTPVECVGDFATFISRIRQ
EECEEEEEEEHHHHCCHHHHHHHHHHCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHHC
DSTIDNGLNLWCVSDNLRKGAALNAVQIAELLGTRVLKKG
CCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GYRVVVAGATGNVGREMLNILAERHFPVDDITVLASRKSLGTEVSFGDKTLKTKDLATF
CEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCHHCCCEECCCCCCCCCCCCEEE
DFTGWDMALFAIGSDATKEFAPKAAKAGCVVIDNSSLYRYDADVPLIVPEVNADAIMDYA
ECCCCCEEEEEECCCHHHHHCCHHHCCCEEEEECCCEEEECCCCCEEEECCCHHHHHHHC
NKNIIANPNCSTAQMVVALKPLHDRATIKRVVVSTYQSVSGAGKEGADELWDQTKSIYNP
CCCEEECCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
TDDKPPKKFTKQIAFNVIPHIDVFMEDGTTKEEWKMVVETKKIIDTKIKVTATCVRVPVF
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCEEEEEEEEEEEEEE
VGHCEAINIEFEEHLDEDEAREILREAPGVMVIDKREDGGYVTPVECVGDFATFISRIRQ
EECEEEEEEEHHHHCCHHHHHHHHHHCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHHC
DSTIDNGLNLWCVSDNLRKGAALNAVQIAELLGTRVLKKG
CCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]