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The map label for this gene is gntR [H]

Identifier: 110677640

GI number: 110677640

Start: 233606

End: 234763

Strand: Direct

Name: gntR [H]

Synonym: RD1_0234

Alternate gene names: 110677640

Gene position: 233606-234763 (Clockwise)

Preceding gene: 110677639

Following gene: 110677641

Centisome position: 5.65

GC content: 59.5

Gene sequence:

>1158_bases
TTGCCAGCCCGCCGTTTCACCGTACTGTTAGCGCATGAACTCGCATGGTTCCGACAGTGCTTGATAGGCAGGCCTTTCGT
AGGCTACCAATGCGCAACAGGACAGGAATTAGCAGTGACCAGACCCAAACACCGACCGTTGACGCTCCGAGATGTTTCTG
AAGCCTGTGGAGTGTCAGAGATGACGGTCAGCCGGGTTTTGCGCAACCGCGGCGATGTTTCTGCAGCTACCCGCGAAAAG
GTTCTGGCCGCGGCAAAGGCGCTTGGCTACGTGCCCAACCAGATCGCCGGATCACTGGCCTCGCAACGGGTCAATCTGGT
GGCGGTCGTGATCCCGTCGCTGTCGAATATGGTCTTTCCCGAAGTGTTGACGGGGATCAACCGGACGCTTGATGACACAC
CGCTGCAACCTGTCGTTGGGGTGACGGATTACCTGCCGGAGAAAGAGGAACAGGTCCTCTATGAGATGCTGTCCTGGCGA
CCATCGGGGGTGATCATTGCCGGGCTTGAGCATTCGGACGCCACGCGCGCCATGCTCACCAATGCCGGTATTCCCGTGGT
TGAAATCATGGATACCGACGGCACGCCCGTGGATTCAATGGTTGGTATCTCGCACCGGCGGGCGGGGCGGAAAATGGCCG
AAGCGATCCTGAAACAAGGTTTTAGCCGGATCGGGTTTCTGGGCACGAAGATGCCGCTGGACCACCGCGCGCGCAAGCGG
TTTGAGGGGTTCACCGAAGGGCTGACCAAGGCCGGGATCGAAATCGAAGACCGCGAATTCTATAACGGCGGCTCTGCGCT
GGCCAAGGGGCGCGAGATGACACAAACGATGCTCGAACGTTCGCCTGATCTGGATTTCCTGTATTATTCCAATGACATGA
TCGGTGCGGGCGGCATGCTTTGGCTGATGGATCAGGGCGTCGATATCCCCGGAGAGGTCGGCCTCGCCGGGTTCAACGGC
GTCGAACTGCTGGAGGGTTTGCCACGCCAGTTGGCGACGATGGACGCCTGCCGCGCCGAGATCGGCGAGAAAGCCGCGCA
AATCATTCTGGACCGCAGTGCCGCGCTGGATACCGAAGACAGTTTCGAGCCCGAACATATCACCCTTGCGCCCAAGATTT
CCTATGGTCAGACGCTGCGTCGCCACGGGCAGGGATGA

Upstream 100 bases:

>100_bases
CCGGGGTCGCCACTTTGGTTGTCATGCGTTCTTGGCTGGTCAACGGCACTTAACGATGCGCGCGGCTTTTTCGACAGGTT
GAAGCACCGGATTTAGCGCA

Downstream 100 bases:

>100_bases
ACACGCTCACCCTGAGCAATACAGACGCCCGGCAGTTGTTTCTGGACCGGCATGCCCTTGCTGAAACGCCTGCCGGTGCG
GCACAGGGTGATGCGCTTCT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MPARRFTVLLAHELAWFRQCLIGRPFVGYQCATGQELAVTRPKHRPLTLRDVSEACGVSEMTVSRVLRNRGDVSAATREK
VLAAAKALGYVPNQIAGSLASQRVNLVAVVIPSLSNMVFPEVLTGINRTLDDTPLQPVVGVTDYLPEKEEQVLYEMLSWR
PSGVIIAGLEHSDATRAMLTNAGIPVVEIMDTDGTPVDSMVGISHRRAGRKMAEAILKQGFSRIGFLGTKMPLDHRARKR
FEGFTEGLTKAGIEIEDREFYNGGSALAKGREMTQTMLERSPDLDFLYYSNDMIGAGGMLWLMDQGVDIPGEVGLAGFNG
VELLEGLPRQLATMDACRAEIGEKAAQIILDRSAALDTEDSFEPEHITLAPKISYGQTLRRHGQG

Sequences:

>Translated_385_residues
MPARRFTVLLAHELAWFRQCLIGRPFVGYQCATGQELAVTRPKHRPLTLRDVSEACGVSEMTVSRVLRNRGDVSAATREK
VLAAAKALGYVPNQIAGSLASQRVNLVAVVIPSLSNMVFPEVLTGINRTLDDTPLQPVVGVTDYLPEKEEQVLYEMLSWR
PSGVIIAGLEHSDATRAMLTNAGIPVVEIMDTDGTPVDSMVGISHRRAGRKMAEAILKQGFSRIGFLGTKMPLDHRARKR
FEGFTEGLTKAGIEIEDREFYNGGSALAKGREMTQTMLERSPDLDFLYYSNDMIGAGGMLWLMDQGVDIPGEVGLAGFNG
VELLEGLPRQLATMDACRAEIGEKAAQIILDRSAALDTEDSFEPEHITLAPKISYGQTLRRHGQG
>Mature_384_residues
PARRFTVLLAHELAWFRQCLIGRPFVGYQCATGQELAVTRPKHRPLTLRDVSEACGVSEMTVSRVLRNRGDVSAATREKV
LAAAKALGYVPNQIAGSLASQRVNLVAVVIPSLSNMVFPEVLTGINRTLDDTPLQPVVGVTDYLPEKEEQVLYEMLSWRP
SGVIIAGLEHSDATRAMLTNAGIPVVEIMDTDGTPVDSMVGISHRRAGRKMAEAILKQGFSRIGFLGTKMPLDHRARKRF
EGFTEGLTKAGIEIEDREFYNGGSALAKGREMTQTMLERSPDLDFLYYSNDMIGAGGMLWLMDQGVDIPGEVGLAGFNGV
ELLEGLPRQLATMDACRAEIGEKAAQIILDRSAALDTEDSFEPEHITLAPKISYGQTLRRHGQG

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=337, Percent_Identity=32.9376854599407, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1790715, Length=341, Percent_Identity=28.7390029325513, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1789202, Length=274, Percent_Identity=27.7372262773723, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786540, Length=282, Percent_Identity=30.1418439716312, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790369, Length=316, Percent_Identity=23.7341772151899, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789068, Length=337, Percent_Identity=25.2225519287834, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788474, Length=315, Percent_Identity=26.6666666666667, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=23.780487804878, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787906, Length=291, Percent_Identity=27.1477663230241, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=24.1269841269841, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=24.0121580547112, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786268, Length=318, Percent_Identity=22.6415094339623, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790689, Length=304, Percent_Identity=23.3552631578947, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 42098; Mature: 41967

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARRFTVLLAHELAWFRQCLIGRPFVGYQCATGQELAVTRPKHRPLTLRDVSEACGVSE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCHHHHHHHCCCHH
MTVSRVLRNRGDVSAATREKVLAAAKALGYVPNQIAGSLASQRVNLVAVVIPSLSNMVFP
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEHHHHHHHHH
EVLTGINRTLDDTPLQPVVGVTDYLPEKEEQVLYEMLSWRPSGVIIAGLEHSDATRAMLT
HHHHHHHCCCCCCCCCCHHCHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHH
NAGIPVVEIMDTDGTPVDSMVGISHRRAGRKMAEAILKQGFSRIGFLGTKMPLDHRARKR
CCCCCEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
FEGFTEGLTKAGIEIEDREFYNGGSALAKGREMTQTMLERSPDLDFLYYSNDMIGAGGML
HHHHHHHHHHCCCEEECCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCEE
WLMDQGVDIPGEVGLAGFNGVELLEGLPRQLATMDACRAEIGEKAAQIILDRSAALDTED
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SFEPEHITLAPKISYGQTLRRHGQG
CCCCCEEEEECCCCHHHHHHHCCCC
>Mature Secondary Structure 
PARRFTVLLAHELAWFRQCLIGRPFVGYQCATGQELAVTRPKHRPLTLRDVSEACGVSE
CCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCHHHHHHHCCCHH
MTVSRVLRNRGDVSAATREKVLAAAKALGYVPNQIAGSLASQRVNLVAVVIPSLSNMVFP
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEHHHHHHHHH
EVLTGINRTLDDTPLQPVVGVTDYLPEKEEQVLYEMLSWRPSGVIIAGLEHSDATRAMLT
HHHHHHHCCCCCCCCCCHHCHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHH
NAGIPVVEIMDTDGTPVDSMVGISHRRAGRKMAEAILKQGFSRIGFLGTKMPLDHRARKR
CCCCCEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
FEGFTEGLTKAGIEIEDREFYNGGSALAKGREMTQTMLERSPDLDFLYYSNDMIGAGGML
HHHHHHHHHHCCCEEECCHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCEE
WLMDQGVDIPGEVGLAGFNGVELLEGLPRQLATMDACRAEIGEKAAQIILDRSAALDTED
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SFEPEHITLAPKISYGQTLRRHGQG
CCCCCEEEEECCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]