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The map label for this gene is cheW [H]

Identifier: 108812125

GI number: 108812125

Start: 2220199

End: 2220696

Strand: Reverse

Name: cheW [H]

Synonym: YPN_1963

Alternate gene names: 108812125

Gene position: 2220696-2220199 (Counterclockwise)

Preceding gene: 108812126

Following gene: 108812121

Centisome position: 48.97

GC content: 47.39

Gene sequence:

>498_bases
ATGGCAGGACTAGCAACCGTCACGAAACTGGCTGGCGAAACGGTAGGACAAGAATTCCTGATTTTTACGCTGGGCGATGA
AGAGTACGGCATCGATATTCTGAAAGTACAAGAGATCCGAGGCTATGATCAGGTGACTCGTATTGCTAACACTCCTGCGT
TTATTAAAGGTGTGACCAACTTACGCGGCGTCATTGTGCCTATCATTGATCTGCGGGTTAAATTCGCCCAGCAAGGTGTC
ACTTATAACGAAAATACCGTGGTGATTGTGCTGAATTTTGGTCAACGCGTGGTGGGTATTGTCGTTGATGGTGTGTCAGA
TGTCCTGTCGTTGACCAACGAGCAGATCCGTCCGGCACCTGAATTTGCTGTGACTCTCGCAACAGAATATCTGACCGGTT
TAGGCTCGCTTGGCGAAAGAATGTTGATCCTGGTTGATATCGAAAAACTGCTGAGCAGTGAAGAGATGTCGTTGATTGAT
AGTGTTTCTAAGGCGTGA

Upstream 100 bases:

>100_bases
ACCACCGGCCACTTTAAATATGACGGGTATCCAGGGCGGTGAAATATGTTTCCGGTCCTGAAAAACATAAATTCAACCTA
TTGATTGAAGGGTAAAAAAC

Downstream 100 bases:

>100_bases
TAATAGTCTTTTTAATATGTGACAATAGTGTTGCTAAGGTGTGATTGAAGCGTGGAGTTTACGCACGTTGAGTGATCACC
TGAGCCAATCGGCCTTAACC

Product: purine-binding chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MAGLATVTKLAGETVGQEFLIFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIIDLRVKFAQQGV
TYNENTVVIVLNFGQRVVGIVVDGVSDVLSLTNEQIRPAPEFAVTLATEYLTGLGSLGERMLILVDIEKLLSSEEMSLID
SVSKA

Sequences:

>Translated_165_residues
MAGLATVTKLAGETVGQEFLIFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIIDLRVKFAQQGV
TYNENTVVIVLNFGQRVVGIVVDGVSDVLSLTNEQIRPAPEFAVTLATEYLTGLGSLGERMLILVDIEKLLSSEEMSLID
SVSKA
>Mature_164_residues
AGLATVTKLAGETVGQEFLIFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIIDLRVKFAQQGVT
YNENTVVIVLNFGQRVVGIVVDGVSDVLSLTNEQIRPAPEFAVTLATEYLTGLGSLGERMLILVDIEKLLSSEEMSLIDS
VSKA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=164, Percent_Identity=83.5365853658537, Blast_Score=278, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 17886; Mature: 17755

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLATVTKLAGETVGQEFLIFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTN
CCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEHHHCCHHHHHHHCCCCHHHHHHHH
LRGVIVPIIDLRVKFAQQGVTYNENTVVIVLNFGQRVVGIVVDGVSDVLSLTNEQIRPAP
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEHHHHHCHHHHHHHHHCCCCCCC
EFAVTLATEYLTGLGSLGERMLILVDIEKLLSSEEMSLIDSVSKA
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
AGLATVTKLAGETVGQEFLIFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTN
CCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEHHHCCHHHHHHHCCCCHHHHHHHH
LRGVIVPIIDLRVKFAQQGVTYNENTVVIVLNFGQRVVGIVVDGVSDVLSLTNEQIRPAP
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEHHHHHCHHHHHHHHHCCCCCCC
EFAVTLATEYLTGLGSLGERMLILVDIEKLLSSEEMSLIDSVSKA
HHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]