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The map label for this gene is shlB [H]

Identifier: 108810186

GI number: 108810186

Start: 34620

End: 36119

Strand: Reverse

Name: shlB [H]

Synonym: YPN_0020

Alternate gene names: 108810186

Gene position: 36119-34620 (Counterclockwise)

Preceding gene: 108810187

Following gene: 108810185

Centisome position: 0.8

GC content: 47.47

Gene sequence:

>1500_bases
GTGAATTATCTCGTCCGGCCCCCCCCCCCTGCACCGGTGTTACCCGAAGATACGCAGTGCCTACCCATTAATGGCGTTTA
TATTCAGGGGATCACCTTATTAACAGAGGATGATTTAAGTGAATTAAGTGCGATCCCTGAACAATGTATTCATCCTGATA
ATATTAACCTTCTGACCCGTGAACTCACTCATATCTATATGGATAAAGGGTATATCACGGCGCGGATTCAATTTATTCCA
CCAGATGCTGACGGAAAATTAGGTCTGGATATTACCGAAGGGTTTGTCGAAGCGATTGATAGCACGGACACCGGGTTAGA
TGGCGAGACGGTATTCCCGAATATGATCGGCAAGCCGCTCAATATTACTCGCCTTGATCAAGGACTGGACCAGGCAAACC
GTTTGCCCTCAAATAAAGTCACCGTCGATATTCTGCCCGGAACACTACCCGGTGGTTCTATTCTTAAACTGCATAATACA
CCGTCAACGCCCTGGCATTTGACCACCTCGATGGACAATTACGGTAATAAAAATACCGGTAAATGGCTAAGTCGCAACGC
CTTATCTTTCGATAATCCGTTGGGCTTATCGGATTCCGTCAGTATCAATATCAGCAATACCGTTGATCGCCCCCAACATA
ATTATAGCCGTGCTTACTCAATGTTTTATTCGGTCCCTTACGGTGCCTTGACCTTTAGTGGCTTTGGTAGTTATGCCGAA
TACCGTTATCCAATGAAATTGCAGTTTAATACAGCCAAGTTACATGGAGAAACACAGCAACACGGTTTACGGGCAGATTA
TGTTTTCTATCGCGATCAAAGCCAGATTAATGGGCTAAGTGCGCAATTAACCTATAAACGGGCCAGTAATTATCTGAATG
AAGAAAAAATTGCTATCAGCAGCCCGACGCTAACAATCTTTGAATTAGGCCTTAATCACCTGCACGTCCTGCCCATGGGC
TTATTCAATATCAATGTCAGCCTTGAGCAGGGCTTGCCTTGGCTGGGCGCGGAGCGCTCAAATGGCCCATTAGCGAACTA
TCAAGATAGCCAATTCACTAAAGCTAAGACCTCAATTACCTCCAATCACTACTTTGCACTGTTTGATGATACCTATCTGT
TCAGCAATCAATTTTATGGCCAGTACACCCGTGACCGGTTACCCGGCGTGGAATGGCTCAGCATCACTGACAGCAGTGCC
ATCCGTGGCTTTAGCCGCAATACCTTATCCGCCGACCAAGGCTGGTATTTACAAAACACCCTCTCCCGTCGTTTCACCTT
GGGTGACGCCACGCTAACCCCTCGCGTAGGGCTTGATACGGGCCGTCTCCAGCAAAAACCACAGGGGTGGGTCAGCGCTA
TGGGGCTAAGCGCTGGCGTCAGCCTTAATTACCAGAATGCCACCTTGGATATAGAAGCCAGCCGTGGCCGGTTACTCTCC
GGCCCATCGAAGATTAACGATCCAACACAAATTCTGGCGCGTTTTTCTTACCGCTTTTAA

Upstream 100 bases:

>100_bases
AATGAATCTCGCCAGTCACTACAAAATAATGCCAAAGAAATTAATCAGCTAGTAGAAGAAAAACGCCACCAACAGATCAC
ACAACACAACACCGGACAAA

Downstream 100 bases:

>100_bases
TGCAATTTTCCCTTGAGAACACCTTGTTACTCATACCAGGAAATATCACCCCAAAATGGAGATGTAAAAATGAAGAAACA
CACCTTTAAGCTCTCACCGG

Product: hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MNYLVRPPPPAPVLPEDTQCLPINGVYIQGITLLTEDDLSELSAIPEQCIHPDNINLLTRELTHIYMDKGYITARIQFIP
PDADGKLGLDITEGFVEAIDSTDTGLDGETVFPNMIGKPLNITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNT
PSTPWHLTTSMDNYGNKNTGKWLSRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGSYAE
YRYPMKLQFNTAKLHGETQQHGLRADYVFYRDQSQINGLSAQLTYKRASNYLNEEKIAISSPTLTIFELGLNHLHVLPMG
LFNINVSLEQGLPWLGAERSNGPLANYQDSQFTKAKTSITSNHYFALFDDTYLFSNQFYGQYTRDRLPGVEWLSITDSSA
IRGFSRNTLSADQGWYLQNTLSRRFTLGDATLTPRVGLDTGRLQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGRLLS
GPSKINDPTQILARFSYRF

Sequences:

>Translated_499_residues
MNYLVRPPPPAPVLPEDTQCLPINGVYIQGITLLTEDDLSELSAIPEQCIHPDNINLLTRELTHIYMDKGYITARIQFIP
PDADGKLGLDITEGFVEAIDSTDTGLDGETVFPNMIGKPLNITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNT
PSTPWHLTTSMDNYGNKNTGKWLSRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGSYAE
YRYPMKLQFNTAKLHGETQQHGLRADYVFYRDQSQINGLSAQLTYKRASNYLNEEKIAISSPTLTIFELGLNHLHVLPMG
LFNINVSLEQGLPWLGAERSNGPLANYQDSQFTKAKTSITSNHYFALFDDTYLFSNQFYGQYTRDRLPGVEWLSITDSSA
IRGFSRNTLSADQGWYLQNTLSRRFTLGDATLTPRVGLDTGRLQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGRLLS
GPSKINDPTQILARFSYRF
>Mature_499_residues
MNYLVRPPPPAPVLPEDTQCLPINGVYIQGITLLTEDDLSELSAIPEQCIHPDNINLLTRELTHIYMDKGYITARIQFIP
PDADGKLGLDITEGFVEAIDSTDTGLDGETVFPNMIGKPLNITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNT
PSTPWHLTTSMDNYGNKNTGKWLSRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGSYAE
YRYPMKLQFNTAKLHGETQQHGLRADYVFYRDQSQINGLSAQLTYKRASNYLNEEKIAISSPTLTIFELGLNHLHVLPMG
LFNINVSLEQGLPWLGAERSNGPLANYQDSQFTKAKTSITSNHYFALFDDTYLFSNQFYGQYTRDRLPGVEWLSITDSSA
IRGFSRNTLSADQGWYLQNTLSRRFTLGDATLTPRVGLDTGRLQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGRLLS
GPSKINDPTQILARFSYRF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 55578; Mature: 55578

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYLVRPPPPAPVLPEDTQCLPINGVYIQGITLLTEDDLSELSAIPEQCIHPDNINLLTR
CCCCCCCCCCCCCCCCCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHH
ELTHIYMDKGYITARIQFIPPDADGKLGLDITEGFVEAIDSTDTGLDGETVFPNMIGKPL
HHHHHEECCCEEEEEEEEECCCCCCEECCCHHHHHHHHHCCCCCCCCCCEECHHHCCCCC
NITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNTPSTPWHLTTSMDNYGNKNTG
CCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCC
KWLSRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGSYAE
CHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHEECCCCCEEECCCCCHHH
YRYPMKLQFNTAKLHGETQQHGLRADYVFYRDQSQINGLSAQLTYKRASNYLNEEKIAIS
EECCEEEEEEEHEECCCHHHCCCEEEEEEEECCHHCCCCEEEEEHHHHHCCCCCCEEEEC
SPTLTIFELGLNHLHVLPMGLFNINVSLEQGLPWLGAERSNGPLANYQDSQFTKAKTSIT
CCCEEEEECCCCEEEEEEEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHEEC
SNHYFALFDDTYLFSNQFYGQYTRDRLPGVEWLSITDSSAIRGFSRNTLSADQGWYLQNT
CCCEEEEEECEEEECCCCCCCHHHHCCCCCEEEEECCCHHHCCCCCCCCCCCCCEEHHHH
LSRRFTLGDATLTPRVGLDTGRLQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGRLLS
HHHEEEECCCEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCEEEEEECCCCCEEC
GPSKINDPTQILARFSYRF
CCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNYLVRPPPPAPVLPEDTQCLPINGVYIQGITLLTEDDLSELSAIPEQCIHPDNINLLTR
CCCCCCCCCCCCCCCCCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHH
ELTHIYMDKGYITARIQFIPPDADGKLGLDITEGFVEAIDSTDTGLDGETVFPNMIGKPL
HHHHHEECCCEEEEEEEEECCCCCCEECCCHHHHHHHHHCCCCCCCCCCEECHHHCCCCC
NITRLDQGLDQANRLPSNKVTVDILPGTLPGGSILKLHNTPSTPWHLTTSMDNYGNKNTG
CCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCC
KWLSRNALSFDNPLGLSDSVSINISNTVDRPQHNYSRAYSMFYSVPYGALTFSGFGSYAE
CHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHEECCCCCEEECCCCCHHH
YRYPMKLQFNTAKLHGETQQHGLRADYVFYRDQSQINGLSAQLTYKRASNYLNEEKIAIS
EECCEEEEEEEHEECCCHHHCCCEEEEEEEECCHHCCCCEEEEEHHHHHCCCCCCEEEEC
SPTLTIFELGLNHLHVLPMGLFNINVSLEQGLPWLGAERSNGPLANYQDSQFTKAKTSIT
CCCEEEEECCCCEEEEEEEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHEEC
SNHYFALFDDTYLFSNQFYGQYTRDRLPGVEWLSITDSSAIRGFSRNTLSADQGWYLQNT
CCCEEEEEECEEEECCCCCCCHHHHCCCCCEEEEECCCHHHCCCCCCCCCCCCCEEHHHH
LSRRFTLGDATLTPRVGLDTGRLQQKPQGWVSAMGLSAGVSLNYQNATLDIEASRGRLLS
HHHEEEECCCEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCEEEEEECCCCCEEC
GPSKINDPTQILARFSYRF
CCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]