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The map label for this gene is desA1 [H]

Identifier: 108801903

GI number: 108801903

Start: 5230475

End: 5231482

Strand: Reverse

Name: desA1 [H]

Synonym: Mmcs_4940

Alternate gene names: 108801903

Gene position: 5231482-5230475 (Counterclockwise)

Preceding gene: 108801907

Following gene: 108801901

Centisome position: 91.69

GC content: 65.67

Gene sequence:

>1008_bases
GTGGCGAAAGACCTGACCCAAGTTCAACTGCTGACCGAGCTCGAACCGGTCGTGGAGGCCAATCTCAACCGGCATCTGCG
CATGCGCAAGGACTGGAACCCGCACGACTTCATCCCGTGGTCGGACGGCAAGAACTACTACGCCCTCGGTGGCCAGGACT
GGGAGCCCGAACAGTCGCAGCTGTCCGAGGTGGCCAGGACCGCGATGGTGCAGAACCTGCTCACCGAGGACAACCTGCCG
TCGTATCACCGCGAGATCGCGATGAACTTCAGCCTCGACGGGGCGTGGGGTCAGTGGGTCAACCGCTGGACGGCCGAGGA
GAACCGGCACGGCATCGCGCTGCGCGACTACCTCACCGTCACCCGCGCGGTCGACCCGGTGGAGCTCGAGGAACTGCGTG
TCGAGCAGATGACCCGCGGGTTCTCGCCCGGGCAGAACGGGCAGGGCGAAGAGGCGCTGTTCGCGAGGAGCCTGTTCGAC
TCGGTCATCTACGTGTCGTTCCAGGAACTCGCGACCCGCGTCTCGCACCGCAACACCGGCAAGGCGTGTAACGACCCGAT
CGCCGATCAGCTGCTGCAGCGGATCTCCGCCGACGAGAACCTGCACATGATCTTCTACCGCGACGTGTCCGAGGCCGGCT
TCGACATCGCGCCCGACCAGGCCATGCACTCGCTGCACCACGTGTTGCGCAACTTCAAGATGCCCGGCTACACCGTGCCC
GACTTCCGGCGGAAGGCCGTCGTGATCGCCGTCGGCGGTGTCTACGACCCGCGGATCCACCTCGACGACGTGGTGATGCC
GGTGCTCAAGAAGTGGCGCATCTTCGAGCGTGAGGACTTCACCGGTGAGGCCGCCCGCATGCGCGACGACCTCGGGGTGC
TGGTCGAGGAGCTCGAGGAGACGTGCGAGAAATTCGAGACCGCCAAACAGCGCCGCCTCGAACGCGAAGCCAAGATGGCC
GAGAACCGCGCGGCCAAACAGGCGGCCAAGCAGGCCGTCTCCGTCTGA

Upstream 100 bases:

>100_bases
ACCGCAATCTAGCCGCCTGAGCGCGTCGGTTCGGATTCTGGCGGTCCCACCCCGTACGCTTACGTGTGACCGCCGTGGAC
ACATACATCTGGGGGACGCC

Downstream 100 bases:

>100_bases
CTCAGCCGAGCCCCGGCACGATGTCGCCGAGGCGGAAGGTGACCGGCTGCTCGAGTTGCGCGTAGGTGCACGAGCGCGGG
TCGCGGTCGGGACGCCAGCG

Product: fatty acid desaturase, type 2

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA1 [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAKDLTQVQLLTELEPVVEANLNRHLRMRKDWNPHDFIPWSDGKNYYALGGQDWEPEQSQLSEVARTAMVQNLLTEDNLP
SYHREIAMNFSLDGAWGQWVNRWTAEENRHGIALRDYLTVTRAVDPVELEELRVEQMTRGFSPGQNGQGEEALFARSLFD
SVIYVSFQELATRVSHRNTGKACNDPIADQLLQRISADENLHMIFYRDVSEAGFDIAPDQAMHSLHHVLRNFKMPGYTVP
DFRRKAVVIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELEETCEKFETAKQRRLEREAKMA
ENRAAKQAAKQAVSV

Sequences:

>Translated_335_residues
MAKDLTQVQLLTELEPVVEANLNRHLRMRKDWNPHDFIPWSDGKNYYALGGQDWEPEQSQLSEVARTAMVQNLLTEDNLP
SYHREIAMNFSLDGAWGQWVNRWTAEENRHGIALRDYLTVTRAVDPVELEELRVEQMTRGFSPGQNGQGEEALFARSLFD
SVIYVSFQELATRVSHRNTGKACNDPIADQLLQRISADENLHMIFYRDVSEAGFDIAPDQAMHSLHHVLRNFKMPGYTVP
DFRRKAVVIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELEETCEKFETAKQRRLEREAKMA
ENRAAKQAAKQAVSV
>Mature_334_residues
AKDLTQVQLLTELEPVVEANLNRHLRMRKDWNPHDFIPWSDGKNYYALGGQDWEPEQSQLSEVARTAMVQNLLTEDNLPS
YHREIAMNFSLDGAWGQWVNRWTAEENRHGIALRDYLTVTRAVDPVELEELRVEQMTRGFSPGQNGQGEEALFARSLFDS
VIYVSFQELATRVSHRNTGKACNDPIADQLLQRISADENLHMIFYRDVSEAGFDIAPDQAMHSLHHVLRNFKMPGYTVPD
FRRKAVVIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELEETCEKFETAKQRRLEREAKMAE
NRAAKQAAKQAVSV

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 38527; Mature: 38396

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDLTQVQLLTELEPVVEANLNRHLRMRKDWNPHDFIPWSDGKNYYALGGQDWEPEQSQ
CCCHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
LSEVARTAMVQNLLTEDNLPSYHREIAMNFSLDGAWGQWVNRWTAEENRHGIALRDYLTV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
TRAVDPVELEELRVEQMTRGFSPGQNGQGEEALFARSLFDSVIYVSFQELATRVSHRNTG
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KACNDPIADQLLQRISADENLHMIFYRDVSEAGFDIAPDQAMHSLHHVLRNFKMPGYTVP
CCCCCHHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
DFRRKAVVIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELEE
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TCEKFETAKQRRLEREAKMAENRAAKQAAKQAVSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKDLTQVQLLTELEPVVEANLNRHLRMRKDWNPHDFIPWSDGKNYYALGGQDWEPEQSQ
CCHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
LSEVARTAMVQNLLTEDNLPSYHREIAMNFSLDGAWGQWVNRWTAEENRHGIALRDYLTV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
TRAVDPVELEELRVEQMTRGFSPGQNGQGEEALFARSLFDSVIYVSFQELATRVSHRNTG
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KACNDPIADQLLQRISADENLHMIFYRDVSEAGFDIAPDQAMHSLHHVLRNFKMPGYTVP
CCCCCHHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
DFRRKAVVIAVGGVYDPRIHLDDVVMPVLKKWRIFEREDFTGEAARMRDDLGVLVEELEE
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TCEKFETAKQRRLEREAKMAENRAAKQAAKQAVSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]