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The map label for this gene is aldH [H]

Identifier: 108801746

GI number: 108801746

Start: 5059341

End: 5060933

Strand: Reverse

Name: aldH [H]

Synonym: Mmcs_4783

Alternate gene names: 108801746

Gene position: 5060933-5059341 (Counterclockwise)

Preceding gene: 108801747

Following gene: 108801741

Centisome position: 88.7

GC content: 72.88

Gene sequence:

>1593_bases
ATGACACCGGCGTCCCAGACTGAACTGACCGGCCAGATGCTCATCGCCGGTGCGGCAGTGCGTGGCGTCGGGCCCGAGAT
CCGCGGCTTCGATCCGACCGCGGGCACCGAACTCGGACCCGGCTACCGCTACGGGGACGCCTCGCATGTCGACGCGGCGT
GCGCTGCCGCGGCCGCGGCGTTCGGGCCGTACCGCAGCACGCCCGCCGAAGCGCGGGCCCGGCTCCTCGAGGCGATCGCC
GACGGTCTCGTCGCGATCACCGACGACCTCGTCGCCCGTGCACACGCCGAATCCGGCCTCCCGCGAGCGCGGCTGACCGG
CGAACTCGGTCGCACCGCGGGACAGCTGCGGCTCTTCGCCGCCGTGCTGCGTGAGGGCAGCTGGAACGGCGTGCGCATCG
ACACCGCCCAACCCGACCGCACCCCGCTGCCCCGTCCGGACCTCCGCCAGCGCGCCGTACCGCTGGGGCCGGTCGCCGTC
TTCGGGGCGAGCAACTTCCCGCTGGCCTTCTCGGTCGCCGGCGGCGACACGGCGTCCGCGCTGGCGGCGGGCTGCCCGGT
CGTCGTCAAGGCGCACGACGCGCACCCGGGCACCTCCGAACTGGTCGGCCGGGTGATCACCGACGCGGTCGCCGCGGCCG
GCCTGCCGCCCGGCACCTTCTCGCTGCTCAATCTCGCGCAGGAAGGCGGCATCACCCTGGTCACCGATCCACGTGTCAAG
GCGGTGGGGTTCACCGGTTCACGGGCCGGCGGGCTGGCGCTCGTCGACGCCGCGGCGCGCCGGAGGGAACCGATCCCCGT
CTACGCGGAGATGAGCGCGGTCAACCCGGTGTTCCTGCTCGACGGCGCGCTCGCCGCCGGCGGAGCCGACCTGGGGCGGG
CGTTCGTCGATTCGCTCACGCTGGGGTCGGGTCAGTTCTGCACCAATCCTGGCCTGATCGTCGCGGTGGACGGACCCGGC
CTCGACACCTTCGTCGACGCCGCGCGCGATGCGCTGGCCGGATCGGCCCCGACGGCGATGCTGACCCCGGGGATCGCGGA
GAACTACCGCGCCGGTGTCGAGGCGCTGGCCGGGCGGGCGACGCTGATCGCCCGCGGGTCGGCCGACGGCACGGCGGCGG
TGTCGTGCCGGGCGGCGTTGTTCGGCACCGACGCGGTCAGCCTGCTCGGGTCGGTGTCGCTGCAGGCGGAGGTCTTCGGA
GCGTCGAGCCTGATCGTGCGTTGCGCCGACTTCGAGGAGATGACGACGGTCGCCGCCAACGTGGAGGGACAGCTGACGGC
CACCCTGCACGCGGACGAATCCGACCACGACCGGGCCGCTGCACTGCTGCCGATCCTCGAACTGAAAGCGGGCCGGATCC
TGTTCAACGGTTGGCCGACCGGCGTCGAGGTCACCCATGCGATGGTGCACGGTGGACCGTTCCCGGCCACTTCGGATTCG
CGCACCACATCGGTCGGATCCCGGGCGATCGAACGGTTTCTGCGCCCTGTCTGCTACCAGAACGCACCGGGGGTGCTGCT
GCCCGCGGCGGTGGCCGACGGCAATCCCGAGTGCCTGTGGCGACGGGTCGACGGGGAACTCACCAGAGACTGA

Upstream 100 bases:

>100_bases
CTGGGCCGCGATGTGCTGGCCCGGCTGGCGGTGCGTGGTCAGCCGCGGGCGTCGTAGCGCAGCTTGGACAGCCGCAGAAC
CGGCGGCTTAGCGTGCAGGT

Downstream 100 bases:

>100_bases
CTCACACCTGACGTGCCTTCAGGCGTTCGGACTCAACGACACCACGGTGATGTCCGGGGGTGCGCCGATTCGCACCGGCG
GACCCCAGAAACCCGCGCCC

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MTPASQTELTGQMLIAGAAVRGVGPEIRGFDPTAGTELGPGYRYGDASHVDAACAAAAAAFGPYRSTPAEARARLLEAIA
DGLVAITDDLVARAHAESGLPRARLTGELGRTAGQLRLFAAVLREGSWNGVRIDTAQPDRTPLPRPDLRQRAVPLGPVAV
FGASNFPLAFSVAGGDTASALAAGCPVVVKAHDAHPGTSELVGRVITDAVAAAGLPPGTFSLLNLAQEGGITLVTDPRVK
AVGFTGSRAGGLALVDAAARRREPIPVYAEMSAVNPVFLLDGALAAGGADLGRAFVDSLTLGSGQFCTNPGLIVAVDGPG
LDTFVDAARDALAGSAPTAMLTPGIAENYRAGVEALAGRATLIARGSADGTAAVSCRAALFGTDAVSLLGSVSLQAEVFG
ASSLIVRCADFEEMTTVAANVEGQLTATLHADESDHDRAAALLPILELKAGRILFNGWPTGVEVTHAMVHGGPFPATSDS
RTTSVGSRAIERFLRPVCYQNAPGVLLPAAVADGNPECLWRRVDGELTRD

Sequences:

>Translated_530_residues
MTPASQTELTGQMLIAGAAVRGVGPEIRGFDPTAGTELGPGYRYGDASHVDAACAAAAAAFGPYRSTPAEARARLLEAIA
DGLVAITDDLVARAHAESGLPRARLTGELGRTAGQLRLFAAVLREGSWNGVRIDTAQPDRTPLPRPDLRQRAVPLGPVAV
FGASNFPLAFSVAGGDTASALAAGCPVVVKAHDAHPGTSELVGRVITDAVAAAGLPPGTFSLLNLAQEGGITLVTDPRVK
AVGFTGSRAGGLALVDAAARRREPIPVYAEMSAVNPVFLLDGALAAGGADLGRAFVDSLTLGSGQFCTNPGLIVAVDGPG
LDTFVDAARDALAGSAPTAMLTPGIAENYRAGVEALAGRATLIARGSADGTAAVSCRAALFGTDAVSLLGSVSLQAEVFG
ASSLIVRCADFEEMTTVAANVEGQLTATLHADESDHDRAAALLPILELKAGRILFNGWPTGVEVTHAMVHGGPFPATSDS
RTTSVGSRAIERFLRPVCYQNAPGVLLPAAVADGNPECLWRRVDGELTRD
>Mature_529_residues
TPASQTELTGQMLIAGAAVRGVGPEIRGFDPTAGTELGPGYRYGDASHVDAACAAAAAAFGPYRSTPAEARARLLEAIAD
GLVAITDDLVARAHAESGLPRARLTGELGRTAGQLRLFAAVLREGSWNGVRIDTAQPDRTPLPRPDLRQRAVPLGPVAVF
GASNFPLAFSVAGGDTASALAAGCPVVVKAHDAHPGTSELVGRVITDAVAAAGLPPGTFSLLNLAQEGGITLVTDPRVKA
VGFTGSRAGGLALVDAAARRREPIPVYAEMSAVNPVFLLDGALAAGGADLGRAFVDSLTLGSGQFCTNPGLIVAVDGPGL
DTFVDAARDALAGSAPTAMLTPGIAENYRAGVEALAGRATLIARGSADGTAAVSCRAALFGTDAVSLLGSVSLQAEVFGA
SSLIVRCADFEEMTTVAANVEGQLTATLHADESDHDRAAALLPILELKAGRILFNGWPTGVEVTHAMVHGGPFPATSDSR
TTSVGSRAIERFLRPVCYQNAPGVLLPAAVADGNPECLWRRVDGELTRD

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=285, Percent_Identity=29.1228070175439, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI25777721, Length=294, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=9e-13,
Organism=Escherichia coli, GI87081896, Length=456, Percent_Identity=28.7280701754386, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788042, Length=465, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789015, Length=309, Percent_Identity=27.1844660194175, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71995606, Length=430, Percent_Identity=26.2790697674419, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71995613, Length=394, Percent_Identity=26.6497461928934, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666674, Length=230, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54057; Mature: 53925

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPASQTELTGQMLIAGAAVRGVGPEIRGFDPTAGTELGPGYRYGDASHVDAACAAAAAA
CCCCCCHHHCHHHEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FGPYRSTPAEARARLLEAIADGLVAITDDLVARAHAESGLPRARLTGELGRTAGQLRLFA
CCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AVLREGSWNGVRIDTAQPDRTPLPRPDLRQRAVPLGPVAVFGASNFPLAFSVAGGDTASA
HHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCEEEEECCCCHHHH
LAAGCPVVVKAHDAHPGTSELVGRVITDAVAAAGLPPGTFSLLNLAQEGGITLVTDPRVK
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCEE
AVGFTGSRAGGLALVDAAARRREPIPVYAEMSAVNPVFLLDGALAAGGADLGRAFVDSLT
EEECCCCCCCCEEEEEHHHHCCCCCCEEEECCCCCEEEEECCCHHCCCHHHHHHHHHHHC
LGSGQFCTNPGLIVAVDGPGLDTFVDAARDALAGSAPTAMLTPGIAENYRAGVEALAGRA
CCCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHCCCE
TLIARGSADGTAAVSCRAALFGTDAVSLLGSVSLQAEVFGASSLIVRCADFEEMTTVAAN
EEEEECCCCCCEEEEEEHHHHCCHHHHHHHCCCEEEEEECCCEEEEEECCHHHHHHHHCC
VEGQLTATLHADESDHDRAAALLPILELKAGRILFNGWPTGVEVTHAMVHGGPFPATSDS
CCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHEEHEECCCCCCCCCCC
RTTSVGSRAIERFLRPVCYQNAPGVLLPAAVADGNPECLWRRVDGELTRD
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHEEEECCCCCCCC
>Mature Secondary Structure 
TPASQTELTGQMLIAGAAVRGVGPEIRGFDPTAGTELGPGYRYGDASHVDAACAAAAAA
CCCCCHHHCHHHEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FGPYRSTPAEARARLLEAIADGLVAITDDLVARAHAESGLPRARLTGELGRTAGQLRLFA
CCCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AVLREGSWNGVRIDTAQPDRTPLPRPDLRQRAVPLGPVAVFGASNFPLAFSVAGGDTASA
HHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCEEEEECCCCHHHH
LAAGCPVVVKAHDAHPGTSELVGRVITDAVAAAGLPPGTFSLLNLAQEGGITLVTDPRVK
HHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEECCCEE
AVGFTGSRAGGLALVDAAARRREPIPVYAEMSAVNPVFLLDGALAAGGADLGRAFVDSLT
EEECCCCCCCCEEEEEHHHHCCCCCCEEEECCCCCEEEEECCCHHCCCHHHHHHHHHHHC
LGSGQFCTNPGLIVAVDGPGLDTFVDAARDALAGSAPTAMLTPGIAENYRAGVEALAGRA
CCCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHCCCE
TLIARGSADGTAAVSCRAALFGTDAVSLLGSVSLQAEVFGASSLIVRCADFEEMTTVAAN
EEEEECCCCCCEEEEEEHHHHCCHHHHHHHCCCEEEEEECCCEEEEEECCHHHHHHHHCC
VEGQLTATLHADESDHDRAAALLPILELKAGRILFNGWPTGVEVTHAMVHGGPFPATSDS
CCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHEEHEECCCCCCCCCCC
RTTSVGSRAIERFLRPVCYQNAPGVLLPAAVADGNPECLWRRVDGELTRD
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]