| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is dacB [H]
Identifier: 108801741
GI number: 108801741
Start: 5054511
End: 5055899
Strand: Reverse
Name: dacB [H]
Synonym: Mmcs_4778
Alternate gene names: 108801741
Gene position: 5055899-5054511 (Counterclockwise)
Preceding gene: 108801746
Following gene: 108801740
Centisome position: 88.62
GC content: 74.23
Gene sequence:
>1389_bases ATGCGGCCCACCCGGTGGCGGCGATCGACCCACGTGCTGGTCGGGCTGGTCGTGCTGGTGCTGGTCGCGGTCGTCGTCGC GGTGGCCGCGGTGTTCACCACCGGCCGCAATTCCGATGCCCAGGCCGCCAAACCCCTGCCCACCCCCGCGACCGCGAACC CGGCCGTCGTGCCGGTCGCCGAATCCGCGCCGACGCCGACCGACGCCGGTCTCGCCGCCGCGCTCGCCCCCGCGCTGGCG GATCCGAACCTCGGCGAGCTGGCCGGGAGGGTCACCGACGCGATGACCGGCGACCCGCTGTGGGACCAGCGCGCCGACGT GCCGATGCAGCCGGCCTCGACGAACAAGGTGCTCACCGCCGCCGCGGCGCTGCTGACGCTGGATCGCGAGGCCCGGCTGA CCACCACGGTGGTGGCCGGGGACCAGAAGCGGGATCCAGGGTTGGTGGTTCTCAAGGGCGGTGGCGATCCGACCCTGTCC GCGGCGCCCCGCGGCACCGACAGCTGGTACCGGGACGCCGCCCGCATCGGCGAACTCGCCGATCAGGTGCGGCGCAGCGG GATCGAAGCGACCGCGGTCGCCGTGGACACCAGCGCCTACACCGGTCCGGAGATGGCGTTCGGCTGGGACCCGCTGGACA TCCCCGGCGGTGACATCGCGCCGATGGTGCCGGTCATGCTCGACGGCGGCCGCACCCAACCGGTCAGCGAGGAGTCGCGG CGCTCACCCACCCCGGCCGCCGACGCCGGGCGCGCGCTGGCCACCGCGTTGCGCATCGACCCCGCCGCGGTCACGGTGCT GCGCGGCCCCTACCGGGGCGGCAGGCAGATCGCGGCCGTGCAGTCACCGCCGCTGATGGAACGGCTGCGGGTGATGATGA ACCTCTCCGACAACGTGATGGCCGAGGCCATCGGTCGGGAAGTGGCCGCCCAACTCGGCCGCCCGCAGAGCTTCGACGAT GCCGCCAAGGCGGTGCTCGCGCAGTTGCGCAAGGCCGGCATCGACACCACGAACGCCCGGTTGTTCGACTCCAGCGGCCT GTCGGTCGACGACCGGCTGACCGCGCGCACCCTCGACGACGTGATCACCGCCGCCGCCGGCGACGACCATCCCGAACTGC GCCCGCTGGTGGACCTGCTGCCGATCGCCGGGGGCAGCGGCACGCTGTCCAACCGCTACCTCGACACCGCCGCGGGGCGC GAGGCCGCCGGATGGCTGCGCGCCAAGACCGGATCGCTGACCGGAACCAACTCGCTGGCCGGCATCGTCACCGACGCCCG CGGCCGCGTGCTGACGTTCGCGCTGATGTCGAACAACGCCGGCCCGACCGGCCGCACGGCCCTCGACGCCCTGGCCGCCA CGCTGCGCGCCTGCGGGTGCGGCTCATGA
Upstream 100 bases:
>100_bases CCGGGGTCGTCGGGTGACGACGACGCGGGTCCACAGTAAACGAGCGATACGCTGCTGTTGGCGGGGTGGTTCGGTCACCT CATTCGACAGCAGGAGTGTT
Downstream 100 bases:
>100_bases GCGCGTCGTCGGCCGACCTCACGGTCGGGCGCACCGTGGACTGGCGCTTCGCGGCCACCGTCGGCGCCAAGCTCGTCCGG CCCGGCCCGCCCGCCACCGA
Product: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase
Products: NA
Alternate protein names: DD-carboxypeptidase; DD-peptidase; D-alanyl-D-alanine endopeptidase; DD-endopeptidase; Penicillin-binding protein 4; PBP-4 [H]
Number of amino acids: Translated: 462; Mature: 462
Protein sequence:
>462_residues MRPTRWRRSTHVLVGLVVLVLVAVVVAVAAVFTTGRNSDAQAAKPLPTPATANPAVVPVAESAPTPTDAGLAAALAPALA DPNLGELAGRVTDAMTGDPLWDQRADVPMQPASTNKVLTAAAALLTLDREARLTTTVVAGDQKRDPGLVVLKGGGDPTLS AAPRGTDSWYRDAARIGELADQVRRSGIEATAVAVDTSAYTGPEMAFGWDPLDIPGGDIAPMVPVMLDGGRTQPVSEESR RSPTPAADAGRALATALRIDPAAVTVLRGPYRGGRQIAAVQSPPLMERLRVMMNLSDNVMAEAIGREVAAQLGRPQSFDD AAKAVLAQLRKAGIDTTNARLFDSSGLSVDDRLTARTLDDVITAAAGDDHPELRPLVDLLPIAGGSGTLSNRYLDTAAGR EAAGWLRAKTGSLTGTNSLAGIVTDARGRVLTFALMSNNAGPTGRTALDALAATLRACGCGS
Sequences:
>Translated_462_residues MRPTRWRRSTHVLVGLVVLVLVAVVVAVAAVFTTGRNSDAQAAKPLPTPATANPAVVPVAESAPTPTDAGLAAALAPALA DPNLGELAGRVTDAMTGDPLWDQRADVPMQPASTNKVLTAAAALLTLDREARLTTTVVAGDQKRDPGLVVLKGGGDPTLS AAPRGTDSWYRDAARIGELADQVRRSGIEATAVAVDTSAYTGPEMAFGWDPLDIPGGDIAPMVPVMLDGGRTQPVSEESR RSPTPAADAGRALATALRIDPAAVTVLRGPYRGGRQIAAVQSPPLMERLRVMMNLSDNVMAEAIGREVAAQLGRPQSFDD AAKAVLAQLRKAGIDTTNARLFDSSGLSVDDRLTARTLDDVITAAAGDDHPELRPLVDLLPIAGGSGTLSNRYLDTAAGR EAAGWLRAKTGSLTGTNSLAGIVTDARGRVLTFALMSNNAGPTGRTALDALAATLRACGCGS >Mature_462_residues MRPTRWRRSTHVLVGLVVLVLVAVVVAVAAVFTTGRNSDAQAAKPLPTPATANPAVVPVAESAPTPTDAGLAAALAPALA DPNLGELAGRVTDAMTGDPLWDQRADVPMQPASTNKVLTAAAALLTLDREARLTTTVVAGDQKRDPGLVVLKGGGDPTLS AAPRGTDSWYRDAARIGELADQVRRSGIEATAVAVDTSAYTGPEMAFGWDPLDIPGGDIAPMVPVMLDGGRTQPVSEESR RSPTPAADAGRALATALRIDPAAVTVLRGPYRGGRQIAAVQSPPLMERLRVMMNLSDNVMAEAIGREVAAQLGRPQSFDD AAKAVLAQLRKAGIDTTNARLFDSSGLSVDDRLTARTLDDVITAAAGDDHPELRPLVDLLPIAGGSGTLSNRYLDTAAGR EAAGWLRAKTGSLTGTNSLAGIVTDARGRVLTFALMSNNAGPTGRTALDALAATLRACGCGS
Specific function: Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction [H]
COG id: COG2027
COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
Gene ontology:
Cell location: Periplasm (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S13 family [H]
Homologues:
Organism=Escherichia coli, GI1789573, Length=164, Percent_Identity=35.3658536585366, Blast_Score=80, Evalue=3e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR000667 [H]
Pfam domain/function: PF02113 Peptidase_S13 [H]
EC number: =3.4.16.4 [H]
Molecular weight: Translated: 47656; Mature: 47656
Theoretical pI: Translated: 5.56; Mature: 5.56
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRPTRWRRSTHVLVGLVVLVLVAVVVAVAAVFTTGRNSDAQAAKPLPTPATANPAVVPVA CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEC ESAPTPTDAGLAAALAPALADPNLGELAGRVTDAMTGDPLWDQRADVPMQPASTNKVLTA CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH AAALLTLDREARLTTTVVAGDQKRDPGLVVLKGGGDPTLSAAPRGTDSWYRDAARIGELA HHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH DQVRRSGIEATAVAVDTSAYTGPEMAFGWDPLDIPGGDIAPMVPVMLDGGRTQPVSEESR HHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCHHHC RSPTPAADAGRALATALRIDPAAVTVLRGPYRGGRQIAAVQSPPLMERLRVMMNLSDNVM CCCCCCHHHHHHHHHHHHCCHHHEEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCHHHH AEAIGREVAAQLGRPQSFDDAAKAVLAQLRKAGIDTTNARLFDSSGLSVDDRLTARTLDD HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHH VITAAAGDDHPELRPLVDLLPIAGGSGTLSNRYLDTAAGREAAGWLRAKTGSLTGTNSLA HHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHEECCCCCCCCCCHH GIVTDARGRVLTFALMSNNAGPTGRTALDALAATLRACGCGS EEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC >Mature Secondary Structure MRPTRWRRSTHVLVGLVVLVLVAVVVAVAAVFTTGRNSDAQAAKPLPTPATANPAVVPVA CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEC ESAPTPTDAGLAAALAPALADPNLGELAGRVTDAMTGDPLWDQRADVPMQPASTNKVLTA CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH AAALLTLDREARLTTTVVAGDQKRDPGLVVLKGGGDPTLSAAPRGTDSWYRDAARIGELA HHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH DQVRRSGIEATAVAVDTSAYTGPEMAFGWDPLDIPGGDIAPMVPVMLDGGRTQPVSEESR HHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCHHHC RSPTPAADAGRALATALRIDPAAVTVLRGPYRGGRQIAAVQSPPLMERLRVMMNLSDNVM CCCCCCHHHHHHHHHHHHCCHHHEEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCHHHH AEAIGREVAAQLGRPQSFDDAAKAVLAQLRKAGIDTTNARLFDSSGLSVDDRLTARTLDD HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHH VITAAAGDDHPELRPLVDLLPIAGGSGTLSNRYLDTAAGREAAGWLRAKTGSLTGTNSLA HHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHEECCCCCCCCCCHH GIVTDARGRVLTFALMSNNAGPTGRTALDALAATLRACGCGS EEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2040429; 9278503; 2046551 [H]