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The map label for this gene is clpC [H]

Identifier: 108801719

GI number: 108801719

Start: 5031777

End: 5034320

Strand: Reverse

Name: clpC [H]

Synonym: Mmcs_4756

Alternate gene names: 108801719

Gene position: 5034320-5031777 (Counterclockwise)

Preceding gene: 108801720

Following gene: 108801718

Centisome position: 88.24

GC content: 66.35

Gene sequence:

>2544_bases
ATGTTCGAACGTTTTACCGACCGTGCCCGCAGGGTCGTCGTCCTGGCTCAAGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGACTCATTCACGAGGGTGAGGGCGTAGCGGCCAAGTCTCTCGAGTCGCTGGGCA
TCTCGCTGGAAGGCGTGCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCGCCGTCCGGTCACATCCCCTTC
ACCCCGCGCGCCAAGAAGGTGCTCGAGCTGTCCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGGTTGATCCGTGAGGGCGAAGGCGTCGCCGCTCAGGTCCTCGTGAAGCTCGGCGCCGAACTGACGCGCG
TGCGCCAGCAGGTCATCCAGCTGCTCAGCGGCTACCAGGGCAAGGAGTCCGCGGAGGCCGGCACCGGCGGCCGCGGCGGC
GAATCCGGCAACCCCTCGACCTCGCTGGTGCTCGACCAGTTCGGCCGCAACCTGACCGCCGCCGCGATGGAGGGCAAGCT
CGACCCCGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGAGCCGCCGCACCAAGAACAACCCGGTCC
TCATCGGAGAGCCCGGCGTCGGCAAGACCGCCGTCGTCGAAGGGCTCGCCCAGGCGATCGTGCACGGCGACGTGCCCGAG
ACGCTGAAGGACAAGCAGCTCTACACCCTCGACCTCGGGTCGCTGGTCGCCGGCAGCCGCTACCGTGGTGACTTCGAGGA
GCGCCTGAAGAAGGTCCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGTTGCACACGCTCGTCG
GCGCGGGTGCCGCCGAGGGTGCGATCGACGCGGCCAGCATCCTGAAGCCGAAGCTAGCCCGCGGTGAGCTGCAGACCATC
GGTGCGACCACCCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCACTGGAACGCCGCTTCCAGCCCGTTCAGGT
CGGCGAGCCGACGGTTGCGCACACCATCGAGATCCTCAAGGGGCTGCGCGACCGCTACGAGGCGCACCACCGCGTGTCGA
TCACCGACGGCGCGATCGCGGCGGCGGCCACCCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCGGACAAGGCGATC
GACCTGATCGACGAGGCCGGTGCGCGCATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAATTCGACGAGAA
GATCGCCGATGCGCGCCGGGAGAAGGAGTCCGCGATCGACGCGCAGGACTTCGAGAAGGCCGCGAGCCTGCGTGACAAGG
AGAAGACCCTCGTCGCGCAGCGTGCCGAGCGTGAGAAGCAGTGGCGCTCGGGTGATCTGGATGTCGTGGCCGAGGTCGAC
GACGAGCAGATCGCCGAGGTGCTCGGCAACTGGACCGGCATCCCCGTGTTCAAGCTGACCGAGGAGGAGACCACTCGGCT
GCTGCGCATGGAGGATGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCGGTCTCGAAGGCGATCCGCC
GCACCCGCGCCGGGCTGAAGGACCCCAAGCGTCCGTCGGGTTCGTTCATCTTCGCCGGCCCGTCAGGTGTCGGTAAGACC
GAGCTCTCGAAGGCGCTGGCGAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGCTTCACCGCGTCGCGGCTGTTCGGTGCCCCTCCGGGCTACGTCGGCTACGAAGAGGGCGGCCAGCTCACCGAGAAGG
TGCGCCGCAAGCCGTTCTCGGTTGTGCTGTTCGACGAGATCGAGAAGGCCCACCAGGAGATCTACAACAGCCTCCTGCAG
GTCCTCGAGGACGGCCGTCTCACCGACGGTCAGGGTCGCACGGTCGACTTCAAGAACACCGTGCTGATCTTCACGTCCAA
CCTCGGCACCTCCGACATCAGCAAGGCGGTCGGGCTGGGCTTCACCCAGGGCGGCGGCGAGAACAACTACGAGCGGATGA
AGCAGAAGGTCAACGACGAGCTGAAGAAGCACTTCCGCCCGGAGTTCCTCAACCGCATCGACGACATCATCGTGTTCCAC
CAGCTCACGCAGGACGAGATCATCAAGATGGTCGACCTGATGATCGGCCGGGTCGGCAATCAGCTGCGGGCCAAGGACAT
GACGATGGAGCTCACCGACAAGGCGAAGTCTCTGCTGGCCAAGCGTGGCTTCGACCCGGTGTTGGGTGCCCGTCCGTTGC
GTCGGACCATCCAGCGCGAGATCGAGGACCAGCTGTCGGAGAAGATCCTGTTCGAGGAGATCGGCCCCGGTCAGCTGATC
ACCGTGGACGTCGAGAACTGGGACGGCCAGGGAGCGGGCGAGGACGCGAAGTTCACCTTCAGCGGTGGTCCGAAGCGGTC
CGAGCCGGTCGAGCCGGATCTGGCGCAGGCCGGCGCTGCCGGTGCGCCGAGCGCAGCCGAGTAA

Upstream 100 bases:

>100_bases
CTGCGGCCGCCCGATAGAGTGGACGGCAGGTGTACCGCAGTTCGGAGAAGTGGTGCGAGCCGCGTACGCCACCTATGCGA
TGGAGAGCAGGTAACCACCG

Downstream 100 bases:

>100_bases
CGACGAGTCGCAAGACGGGCGGTCACCCCACGGTGGCCGCCCGTCTCGTCTTTCTCGGCGTCGACGGAGGGCCGCGGCGC
GATTCCCGCGCGCAGTGCTT

Product: ATPase AAA-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 847; Mature: 847

Protein sequence:

>847_residues
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKESAEAGTGGRGG
ESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVAHTIEILKGLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDKEKTLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTQDEIIKMVDLMIGRVGNQLRAKDMTMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQLI
TVDVENWDGQGAGEDAKFTFSGGPKRSEPVEPDLAQAGAAGAPSAAE

Sequences:

>Translated_847_residues
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKESAEAGTGGRGG
ESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVAHTIEILKGLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDKEKTLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTQDEIIKMVDLMIGRVGNQLRAKDMTMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQLI
TVDVENWDGQGAGEDAKFTFSGGPKRSEPVEPDLAQAGAAGAPSAAE
>Mature_847_residues
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKESAEAGTGGRGG
ESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVAHTIEILKGLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDKEKTLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTQDEIIKMVDLMIGRVGNQLRAKDMTMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQLI
TVDVENWDGQGAGEDAKFTFSGGPKRSEPVEPDLAQAGAAGAPSAAE

Specific function: Part Of A Stress-Induced Multi-Chaperone System, It Is Involved In The Recovery Of The Cell From Heat-Induced Damage, In Cooperation With Dnak, Dnaj And Grpe. Acts Before Dnak, In The Processing Of Protein Aggregates. Protein Binding Stimulates The Atpase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=323, Percent_Identity=34.3653250773994, Blast_Score=195, Evalue=1e-49,
Organism=Escherichia coli, GI1788943, Length=875, Percent_Identity=46.0571428571429, Blast_Score=726, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=811, Percent_Identity=38.347718865598, Blast_Score=517, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6320464, Length=700, Percent_Identity=47, Blast_Score=606, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6323002, Length=429, Percent_Identity=40.5594405594406, Blast_Score=294, Evalue=5e-80,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 93427; Mature: 93427

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVR
CCCHHHHHCCEEEEEEHHHHHHHHCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCHHHHH
SQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCHH
AQVLVKLGAELTRVRQQVIQLLSGYQGKESAEAGTGGRGGESGNPSTSLVLDQFGRNLTA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEH
AAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCH
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
HHCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCC
AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVAHTIEILK
CHHHHHHHCCHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPD
HHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCC
LREFDEKIADARREKESAIDAQDFEKAASLRDKEKTLVAQRAEREKQWRSGDLDVVAEVD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLK
HHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCC
YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDGQGRTVDFKNT
CCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
EEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLTQDEIIKMVDLMIGRVGNQLRAKDMTMELTDKAKSLLAKRGFDPVLGARPLRRTIQRE
HCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
IEDQLSEKILFEEIGPGQLITVDVENWDGQGAGEDAKFTFSGGPKRSEPVEPDLAQAGAA
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHCCCC
GAPSAAE
CCCCCCC
>Mature Secondary Structure
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVR
CCCHHHHHCCEEEEEEHHHHHHHHCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCHHHHH
SQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCHH
AQVLVKLGAELTRVRQQVIQLLSGYQGKESAEAGTGGRGGESGNPSTSLVLDQFGRNLTA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEH
AAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGDVPE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCH
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
HHCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCC
AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVAHTIEILK
CHHHHHHHCCHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GLRDRYEAHHRVSITDGAIAAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPD
HHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCC
LREFDEKIADARREKESAIDAQDFEKAASLRDKEKTLVAQRAEREKQWRSGDLDVVAEVD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLK
HHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCC
YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDGQGRTVDFKNT
CCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
EEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLTQDEIIKMVDLMIGRVGNQLRAKDMTMELTDKAKSLLAKRGFDPVLGARPLRRTIQRE
HCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
IEDQLSEKILFEEIGPGQLITVDVENWDGQGAGEDAKFTFSGGPKRSEPVEPDLAQAGAA
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHCCCC
GAPSAAE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]