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The map label for this gene is purC [H]

Identifier: 108801523

GI number: 108801523

Start: 4834822

End: 4835715

Strand: Reverse

Name: purC [H]

Synonym: Mmcs_4560

Alternate gene names: 108801523

Gene position: 4835715-4834822 (Counterclockwise)

Preceding gene: 108801525

Following gene: 108801522

Centisome position: 84.76

GC content: 67.45

Gene sequence:

>894_bases
ATGCGCCCCGCTCTGTCCGACTACCGCCATCTGGCCAGCGGCAAGGTTCGCGAGTTGTACCGCATCGACGACGAGCACCT
GCTGTTCGTCGCCACCGACCGCATCTCGGCGTACGACCACATCCTGTCCTCGGAGATCCCGGACAAGGGCCGCATCCTCA
CCGCGATGAGCGTGTTCTTCTTCGACCTCATCGACGCCCCCAACCACCTCGCGGGCCCACCCGACGACCCGCGCATCCCC
GAGGAGGTGCTCGGCCGCGCGCTCGTGGTGCGCCAACTGGAGATGCTGCCCGTCGAATGTGTGGCCCGCGGCTACCTCAC
CGGGTCGGGGCTGATCGACTACCGCAAGACCGGCACGCTGTGCGGACTGACGCTGCCGCCCGGGCTCACCGAGGCGAGCA
AGTTCGCCGAACCGCTCTACACGCCGGCGTCCAAGGCCGAACTCGGTCTGCACGACGAGAACATCGACTTCGCCGCCACC
GTCGACCTGGTCGGGGAGAAGCGCGCCGCCCAGCTGCGTGAGCGCACGCTGCAGATCTACACCCAGGGCGCCGACCACGC
GCTGACGAAGGGAATCATCATCGCCGACACCAAATTCGAGTTCGGGGTCGATCCGTCGGGCGAACTGGTACTCGCCGACG
AGGTGTTCACCCCCGACTCGTCGCGGTACTGGTACGCGGACGCCTACCGCGAGGGGCAGGTGCAACCCAGCTACGACAAA
CAGTTCGTCCGCAACTGGCTCACCGGCCCGGAGTCCGGCTGGGACCGCGCCGCCGATCAACCCCCGCCGCCGCTTCCCGC
CGAGATCGTCGACGCCACCCGTTCGCGTTACATCGAAGCCTACGAACGCATTTCGGGTCTGAGCTTCGCCGAGTGGATCG
GCGCGAGCGCATGA

Upstream 100 bases:

>100_bases
GATGTCGCTGATCAGCTGGCCGAGCAGGCGGCCGGGGGTGGTGGCGTAGGGCACAAACCGCGAAGTCATGTGTGTAGATG
CTGCCCGATAGGCTGGCCCG

Downstream 100 bases:

>100_bases
CCGTCCCGCCGCCGCAGGCCAAACGGGTTGAACAGCGGCGCGAACACCACGGCGACGTGTTCATCGACCCCTACGAGTGG
CTGCGCGACAAATCCGATCC

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MRPALSDYRHLASGKVRELYRIDDEHLLFVATDRISAYDHILSSEIPDKGRILTAMSVFFFDLIDAPNHLAGPPDDPRIP
EEVLGRALVVRQLEMLPVECVARGYLTGSGLIDYRKTGTLCGLTLPPGLTEASKFAEPLYTPASKAELGLHDENIDFAAT
VDLVGEKRAAQLRERTLQIYTQGADHALTKGIIIADTKFEFGVDPSGELVLADEVFTPDSSRYWYADAYREGQVQPSYDK
QFVRNWLTGPESGWDRAADQPPPPLPAEIVDATRSRYIEAYERISGLSFAEWIGASA

Sequences:

>Translated_297_residues
MRPALSDYRHLASGKVRELYRIDDEHLLFVATDRISAYDHILSSEIPDKGRILTAMSVFFFDLIDAPNHLAGPPDDPRIP
EEVLGRALVVRQLEMLPVECVARGYLTGSGLIDYRKTGTLCGLTLPPGLTEASKFAEPLYTPASKAELGLHDENIDFAAT
VDLVGEKRAAQLRERTLQIYTQGADHALTKGIIIADTKFEFGVDPSGELVLADEVFTPDSSRYWYADAYREGQVQPSYDK
QFVRNWLTGPESGWDRAADQPPPPLPAEIVDATRSRYIEAYERISGLSFAEWIGASA
>Mature_297_residues
MRPALSDYRHLASGKVRELYRIDDEHLLFVATDRISAYDHILSSEIPDKGRILTAMSVFFFDLIDAPNHLAGPPDDPRIP
EEVLGRALVVRQLEMLPVECVARGYLTGSGLIDYRKTGTLCGLTLPPGLTEASKFAEPLYTPASKAELGLHDENIDFAAT
VDLVGEKRAAQLRERTLQIYTQGADHALTKGIIIADTKFEFGVDPSGELVLADEVFTPDSSRYWYADAYREGQVQPSYDK
QFVRNWLTGPESGWDRAADQPPPPLPAEIVDATRSRYIEAYERISGLSFAEWIGASA

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=296, Percent_Identity=44.5945945945946, Blast_Score=257, Evalue=1e-69,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 32973; Mature: 32973

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS01057 SAICAR_SYNTHETASE_1 ; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPALSDYRHLASGKVRELYRIDDEHLLFVATDRISAYDHILSSEIPDKGRILTAMSVFF
CCCCHHHHHHHHCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHH
FDLIDAPNHLAGPPDDPRIPEEVLGRALVVRQLEMLPVECVARGYLTGSGLIDYRKTGTL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCE
CGLTLPPGLTEASKFAEPLYTPASKAELGLHDENIDFAATVDLVGEKRAAQLRERTLQIY
EEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHH
TQGADHALTKGIIIADTKFEFGVDPSGELVLADEVFTPDSSRYWYADAYREGQVQPSYDK
CCCCCHHHHCCEEEEECCEEECCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCHHH
QFVRNWLTGPESGWDRAADQPPPPLPAEIVDATRSRYIEAYERISGLSFAEWIGASA
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
>Mature Secondary Structure
MRPALSDYRHLASGKVRELYRIDDEHLLFVATDRISAYDHILSSEIPDKGRILTAMSVFF
CCCCHHHHHHHHCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHH
FDLIDAPNHLAGPPDDPRIPEEVLGRALVVRQLEMLPVECVARGYLTGSGLIDYRKTGTL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCE
CGLTLPPGLTEASKFAEPLYTPASKAELGLHDENIDFAATVDLVGEKRAAQLRERTLQIY
EEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHH
TQGADHALTKGIIIADTKFEFGVDPSGELVLADEVFTPDSSRYWYADAYREGQVQPSYDK
CCCCCHHHHCCEEEEECCEEECCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCHHH
QFVRNWLTGPESGWDRAADQPPPPLPAEIVDATRSRYIEAYERISGLSFAEWIGASA
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA