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The map label for this gene is pgaC [H]

Identifier: 108801525

GI number: 108801525

Start: 4836292

End: 4838247

Strand: Reverse

Name: pgaC [H]

Synonym: Mmcs_4562

Alternate gene names: 108801525

Gene position: 4838247-4836292 (Counterclockwise)

Preceding gene: 108801526

Following gene: 108801523

Centisome position: 84.8

GC content: 68.05

Gene sequence:

>1956_bases
GTGAACGAACCGGTAGCGCGGCAGCACCGGGACTCCCAGACGCCATCGGCACCGCCGCCGCAGATACCGCAGAAGCCCAA
AGCTGTTGTCAGGCACTATCGCTCGATCGACAGCGCTCCGCCGGCGTATGCGGTCAAACGTCCGCCCAGCGCTGTCAACG
GTGCGCTGCTCATCTTTGTCGCGTTGAGCAGTCTGACGCTGCTGCTCGGAACCGTACAGGCCAGGGCGTGGGGAGACCAC
GCCCGCGACCTGGTCTTCGCCACGGCCGACGGGCAGGCGGCCGCGATACCGGTGCGGGCGTTCCTGCTGGTGATGGTCAC
CTCGGTGGCGTGGTCGCTGGACACGAACTTCTGGCGCCGGTTGGCTGTGCACCTCGAGCTGACCGGCGTGCTGATCCTGG
TCTGCGCGGTGGTGGATTTCTCGGCTTACCTCGGCTACCACGTCGGACTCTTCTATCCGCAGATCGTCGGCCAGCAGTTG
GCGTCAAGCCTGGCGGCGATGGTGCTGTTGCCGTTCACCGTGATGCGGCACGCCCGGCTGCCGAGGCCGGCGCGCCTGCG
GCCGGCGGGGCGGATGCGTTGGCATGCCTGGGTGCGGCTGGCGGTTCCGCTGGCGGTGGCGTTCGTGGCAGCCGCCTGGA
TCGAGGACCGCATGCCGGTCCCGGTGGCCTGGATGCGGGAGTGGGCGCTGATGGGTGGCGTGGGTCCGGGGATCTTCCTG
GTCCAGCAGCTGTTCGGCATCCTCGCCGCGGGGATCGGGCTGGTGATGATCCGCCGGTCGCGCCGCGCACGTTTCGCGCC
GCCCCTCGCGGTGATCATCCCGGCGCACAACGAGGCCCACGACATCACCGCCACGATCGAGGCCGTCGACCGGGCCGCGG
CCCGGTACGCCGAGACGGTCCACATCTATGTCATCGACAATGCCTCCACCGACGACACCGCGGACGTCGCACAGACCGCC
ATCGCCGCCTGCGCACACTCCACCGGGGAGGTGCACGAATGCGCGGTCCCCGGGAAGGCGGTGGCGCTCAACTACGGCCT
GTCGGTGATCCGGGAGGAGTTCGTCGTGCGCATCGATGCCGACACCGTGATCGGCGAGAACTGCCTCGACGTCACGCTGC
GTCATTTCACCGATGCGAAGGTCGCCGCCGTCGGCGGGATGCCGCGGCCGGAACGTATCCGAACCTTCTTCGACCGGGTG
CGATTGGTCGAGGTGCTCGTCAAACACGGCTTCTTCCAGGTCGCGATGATGGGCTACGACGGGATCATCGGCGAGCCCGG
CATGTTCGTGGTCTACCGGCGCCGCGTCGTCGAAGAGGTCGGCGGCATCGTGCAGGGCATGAACGGTGAGGACACCGACA
TCTGCATGAGGATGAGCAGTCAGGGCTACCTGAGCCTGGTCGACCCCACCGCGGTCTACTTCAGCGAGACCCCGCAGAGC
TGGGCGCATCTGCGCGAACAACGCACCCGCTGGTTTCGCAGCATCTACCACATCGCCGCCCACAACCGGCACGCGATCCT
GAGCCGGAGTTCGATGGCCGGGGCGGTGATGCTGCCGTTTCAGCTCGCCAACTCGGCGCGCCGAGCGATGATGCTGCCCC
TGCTGTTGTTCGGCCTCTTGATCTTCGGACTGTTCCGCGAGTCGTTCCCCGGTCTGCACCCCGAGCGGCTCCTCGCGGTG
TTCCTCGGGCTGCCGCTGCTGGTGGCACTCGGCGTATGCCTCGTGCGTCAGCCCCGAGCGGTCCTCTACCTCCCCGAGTA
CCTCCTATTCCGGATAGTGCGCAGCTATTTCACCCTCGCCGCGGTGCTGAGCCTGGTGTTTCCGCCGCTGCATCCCCGGC
AGGCGCTGCGGGAGCGAAGGCGAACGCGTAGGCGACCCCGTCACCGACGCAACCGTGCCACGCCCGCCGACCGCAGTTCC
AGCGCCGCAAGCCCGGATATCGCGGCGACGTCCTGA

Upstream 100 bases:

>100_bases
GCTACGGGCGCGAGTCCGCCAGGCTGGTGACCGGTGACGGTGTCGGGGTGGCGGTCGATGACGCCGGGCGCCTCGACGGC
CCTCTGCCGGTGCGAGATCC

Downstream 100 bases:

>100_bases
TTGCGCCATGCCCCGACCGGGTCGGCGTCGACGCTGACCAGCTTGGCCAGCGGCCGGTTGGCCAGCGCCCGCAGCGCGAG
CAACTGCTGACCCGCCGGCG

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: PGA synthase; Poly-beta-1,6-GlcNAc synthase; Biofilm PGA synthesis protein PgaC; N-acetylglucosaminyltransferase PgaC [H]

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MNEPVARQHRDSQTPSAPPPQIPQKPKAVVRHYRSIDSAPPAYAVKRPPSAVNGALLIFVALSSLTLLLGTVQARAWGDH
ARDLVFATADGQAAAIPVRAFLLVMVTSVAWSLDTNFWRRLAVHLELTGVLILVCAVVDFSAYLGYHVGLFYPQIVGQQL
ASSLAAMVLLPFTVMRHARLPRPARLRPAGRMRWHAWVRLAVPLAVAFVAAAWIEDRMPVPVAWMREWALMGGVGPGIFL
VQQLFGILAAGIGLVMIRRSRRARFAPPLAVIIPAHNEAHDITATIEAVDRAAARYAETVHIYVIDNASTDDTADVAQTA
IAACAHSTGEVHECAVPGKAVALNYGLSVIREEFVVRIDADTVIGENCLDVTLRHFTDAKVAAVGGMPRPERIRTFFDRV
RLVEVLVKHGFFQVAMMGYDGIIGEPGMFVVYRRRVVEEVGGIVQGMNGEDTDICMRMSSQGYLSLVDPTAVYFSETPQS
WAHLREQRTRWFRSIYHIAAHNRHAILSRSSMAGAVMLPFQLANSARRAMMLPLLLFGLLIFGLFRESFPGLHPERLLAV
FLGLPLLVALGVCLVRQPRAVLYLPEYLLFRIVRSYFTLAAVLSLVFPPLHPRQALRERRRTRRRPRHRRNRATPADRSS
SAASPDIAATS

Sequences:

>Translated_651_residues
MNEPVARQHRDSQTPSAPPPQIPQKPKAVVRHYRSIDSAPPAYAVKRPPSAVNGALLIFVALSSLTLLLGTVQARAWGDH
ARDLVFATADGQAAAIPVRAFLLVMVTSVAWSLDTNFWRRLAVHLELTGVLILVCAVVDFSAYLGYHVGLFYPQIVGQQL
ASSLAAMVLLPFTVMRHARLPRPARLRPAGRMRWHAWVRLAVPLAVAFVAAAWIEDRMPVPVAWMREWALMGGVGPGIFL
VQQLFGILAAGIGLVMIRRSRRARFAPPLAVIIPAHNEAHDITATIEAVDRAAARYAETVHIYVIDNASTDDTADVAQTA
IAACAHSTGEVHECAVPGKAVALNYGLSVIREEFVVRIDADTVIGENCLDVTLRHFTDAKVAAVGGMPRPERIRTFFDRV
RLVEVLVKHGFFQVAMMGYDGIIGEPGMFVVYRRRVVEEVGGIVQGMNGEDTDICMRMSSQGYLSLVDPTAVYFSETPQS
WAHLREQRTRWFRSIYHIAAHNRHAILSRSSMAGAVMLPFQLANSARRAMMLPLLLFGLLIFGLFRESFPGLHPERLLAV
FLGLPLLVALGVCLVRQPRAVLYLPEYLLFRIVRSYFTLAAVLSLVFPPLHPRQALRERRRTRRRPRHRRNRATPADRSS
SAASPDIAATS
>Mature_651_residues
MNEPVARQHRDSQTPSAPPPQIPQKPKAVVRHYRSIDSAPPAYAVKRPPSAVNGALLIFVALSSLTLLLGTVQARAWGDH
ARDLVFATADGQAAAIPVRAFLLVMVTSVAWSLDTNFWRRLAVHLELTGVLILVCAVVDFSAYLGYHVGLFYPQIVGQQL
ASSLAAMVLLPFTVMRHARLPRPARLRPAGRMRWHAWVRLAVPLAVAFVAAAWIEDRMPVPVAWMREWALMGGVGPGIFL
VQQLFGILAAGIGLVMIRRSRRARFAPPLAVIIPAHNEAHDITATIEAVDRAAARYAETVHIYVIDNASTDDTADVAQTA
IAACAHSTGEVHECAVPGKAVALNYGLSVIREEFVVRIDADTVIGENCLDVTLRHFTDAKVAAVGGMPRPERIRTFFDRV
RLVEVLVKHGFFQVAMMGYDGIIGEPGMFVVYRRRVVEEVGGIVQGMNGEDTDICMRMSSQGYLSLVDPTAVYFSETPQS
WAHLREQRTRWFRSIYHIAAHNRHAILSRSSMAGAVMLPFQLANSARRAMMLPLLLFGLLIFGLFRESFPGLHPERLLAV
FLGLPLLVALGVCLVRQPRAVLYLPEYLLFRIVRSYFTLAAVLSLVFPPLHPRQALRERRRTRRRPRHRRNRATPADRSS
SAASPDIAATS

Specific function: Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N- acetylglucosamine to produce the linear homopolymer poly-beta-1,6- N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide [H]

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=226, Percent_Identity=26.1061946902655, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 72043; Mature: 72043

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEPVARQHRDSQTPSAPPPQIPQKPKAVVRHYRSIDSAPPAYAVKRPPSAVNGALLIFV
CCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHH
ALSSLTLLLGTVQARAWGDHARDLVFATADGQAAAIPVRAFLLVMVTSVAWSLDTNFWRR
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVHLELTGVLILVCAVVDFSAYLGYHVGLFYPQIVGQQLASSLAAMVLLPFTVMRHARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRPARLRPAGRMRWHAWVRLAVPLAVAFVAAAWIEDRMPVPVAWMREWALMGGVGPGIFL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHH
VQQLFGILAAGIGLVMIRRSRRARFAPPLAVIIPAHNEAHDITATIEAVDRAAARYAETV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCEE
HIYVIDNASTDDTADVAQTAIAACAHSTGEVHECAVPGKAVALNYGLSVIREEFVVRIDA
EEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEHHHHHHHHHHHHEEEECC
DTVIGENCLDVTLRHFTDAKVAAVGGMPRPERIRTFFDRVRLVEVLVKHGFFQVAMMGYD
CHHHCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEHEECCC
GIIGEPGMFVVYRRRVVEEVGGIVQGMNGEDTDICMRMSSQGYLSLVDPTAVYFSETPQS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCEEEECCHHHEECCCCHH
WAHLREQRTRWFRSIYHIAAHNRHAILSRSSMAGAVMLPFQLANSARRAMMLPLLLFGLL
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
IFGLFRESFPGLHPERLLAVFLGLPLLVALGVCLVRQPRAVLYLPEYLLFRIVRSYFTLA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHH
AVLSLVFPPLHPRQALRERRRTRRRPRHRRNRATPADRSSSAASPDIAATS
HHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNEPVARQHRDSQTPSAPPPQIPQKPKAVVRHYRSIDSAPPAYAVKRPPSAVNGALLIFV
CCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHH
ALSSLTLLLGTVQARAWGDHARDLVFATADGQAAAIPVRAFLLVMVTSVAWSLDTNFWRR
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVHLELTGVLILVCAVVDFSAYLGYHVGLFYPQIVGQQLASSLAAMVLLPFTVMRHARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRPARLRPAGRMRWHAWVRLAVPLAVAFVAAAWIEDRMPVPVAWMREWALMGGVGPGIFL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHH
VQQLFGILAAGIGLVMIRRSRRARFAPPLAVIIPAHNEAHDITATIEAVDRAAARYAETV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCEE
HIYVIDNASTDDTADVAQTAIAACAHSTGEVHECAVPGKAVALNYGLSVIREEFVVRIDA
EEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEHHHHHHHHHHHHEEEECC
DTVIGENCLDVTLRHFTDAKVAAVGGMPRPERIRTFFDRVRLVEVLVKHGFFQVAMMGYD
CHHHCCHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHEEHEECCC
GIIGEPGMFVVYRRRVVEEVGGIVQGMNGEDTDICMRMSSQGYLSLVDPTAVYFSETPQS
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEECCCCCEEEECCHHHEECCCCHH
WAHLREQRTRWFRSIYHIAAHNRHAILSRSSMAGAVMLPFQLANSARRAMMLPLLLFGLL
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
IFGLFRESFPGLHPERLLAVFLGLPLLVALGVCLVRQPRAVLYLPEYLLFRIVRSYFTLA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHH
AVLSLVFPPLHPRQALRERRRTRRRPRHRRNRATPADRSSSAASPDIAATS
HHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]