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The map label for this gene is crtI [H]

Identifier: 108801468

GI number: 108801468

Start: 4782328

End: 4783890

Strand: Reverse

Name: crtI [H]

Synonym: Mmcs_4505

Alternate gene names: 108801468

Gene position: 4783890-4782328 (Counterclockwise)

Preceding gene: 108801469

Following gene: 108801466

Centisome position: 83.85

GC content: 70.44

Gene sequence:

>1563_bases
ATGCCGGACTTCGACGTGGTCGTCATCGGCGCCGGGCACAACGGGCTCACCGCGGCGGCCCTTCTGCAGCGGTCAGGACT
GCGCACCGTCTGCCTGGAGGCCAAGCGGTACGCCGGCGGGATGGCCTCGACCGTCGAACTGTTCGACGGGTACCGCTTCG
AGATCGCCGGCTCCCTGCAGTTCCCGACGTCGGCGACGGTCAGCCGGGAACTCGGCCTCGACGAACTGCCCACCGTCGAC
CTCGAGGTGATGTCGGTGTCGCTGCGCGGCGTCGGCGACGCCCCGGTCGTCTACTACACCGATCCGATGCGGATGCTGAC
CCACCTCGACGAGGTGCACGGCGCCGACGCCGTCGCCGGGATGGCCGGTCTGATGGCGTGGAGTCAGGGGCCGACGCGGG
CTCTCGGCCGGTTCGACGCCGATCGCCCGCCCAGATCGCTCGACGAGATGTACGCCTGTGCCGCAACCCCGTTCGAACGC
GCCGCGATCACCGACATGCTGTTCGGGTCGGTCAGCGACGTTCTGGACCGCTATCTGCCCGACCGTGAGAAACACGGCGC
GCTGCGCGGCATGCTGGCGTTCCTCGCCGTCAACACCACCTACCGCGGGCCCGCGACGCCGGGCAGTGCGGCGGCGCTGG
CCTTCGGCCTGGCCGTGCCGGACGAGAACGCCGCGCTGATGAAGAAACTGCGCGGCGGGATCGGCGCCCTCACCGACCAC
CTGTGCCGCCTGTTCACCGAGGCCGGCGGAGAGGTCCGGCTGCGCAGCAAGGTCGAGCGGATCGCGGTCGCCGACGGGCG
CGTCTCCGGTGTCGCGCTCGAGGACGGGACAACGCTCACCGCGCACACGGTCGTCTCGGCCGTCGCCCCCGACCTCACCG
TGACCGCACTGCTCGACCCCGACGCCGTAACCGCCGACCTCCGTGACCGCTTCGCACGCATCGACCACCGGGGCAGCTAT
CTGCAGATGCACTTCGCGCTGGACGCCGCCCCCACCTTCGCCGCACCGTACGAGATGCTCAACGATCCCGAGTTGCAGGC
GGCCATTGGGCTGTTCAGCACGCCGGAGGAGCTGCAGAGCCAGTGGGAGGACTGCCGGCGCGGTGTGGTGCCGGCCGACC
CCGCGATCGCGCTGCAGATCCCCTCGGCGCACGATCCCACGCTCGCGCTCCCCGGTAAGCACGCCGCGTCGGCGTTCGCG
CTGTGGTTCCCCGTCGAGACCGACCACGCCCGCTACGGGGAGATGAAGACCGAGATGGGCCGGCGGGTGATCGAGAAGAT
CACCCGCATCGCACCGGATTTCACCGACCTCATCACCCGGCACACCACGTTCACCCCACGCCACATGGGGACGATGTTCG
GGGCGCCGGGCGGCGACTACTGCCATGGCCTGATCCACCCCGAGCAGATGGGCCCGAACCGGCCCGGCCCGAAAGGGTAT
GTGGATCAACCGCTTCCGGTCGACGGCCTCTACCTGGCCAGTGCCGGATGCCACGGCGGGCCGGGCATCACGTTCATCCC
CGGCTACAACGCCGCGCGTCAGGCGCTGACCGACCTGGGCTGA

Upstream 100 bases:

>100_bases
CGCTCGCTCCCGGAGCTGTCCAGGCTCTGCCGCACCGCACTCGAGAGCCTCGAGTTTCGTCAATATTGACAAAACTTCGG
GCCGGTGACAGCCTCGGTCC

Downstream 100 bases:

>100_bases
GCCCTCACACCCCGACGGCGACCTCGAGTTCCTTGAGCGAATCCTCGAGGTGGCCGAGCAGCCGCTGCAGGTGAGGCACG
CTGCCGCGGGCGCCGACCAG

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MPDFDVVVIGAGHNGLTAAALLQRSGLRTVCLEAKRYAGGMASTVELFDGYRFEIAGSLQFPTSATVSRELGLDELPTVD
LEVMSVSLRGVGDAPVVYYTDPMRMLTHLDEVHGADAVAGMAGLMAWSQGPTRALGRFDADRPPRSLDEMYACAATPFER
AAITDMLFGSVSDVLDRYLPDREKHGALRGMLAFLAVNTTYRGPATPGSAAALAFGLAVPDENAALMKKLRGGIGALTDH
LCRLFTEAGGEVRLRSKVERIAVADGRVSGVALEDGTTLTAHTVVSAVAPDLTVTALLDPDAVTADLRDRFARIDHRGSY
LQMHFALDAAPTFAAPYEMLNDPELQAAIGLFSTPEELQSQWEDCRRGVVPADPAIALQIPSAHDPTLALPGKHAASAFA
LWFPVETDHARYGEMKTEMGRRVIEKITRIAPDFTDLITRHTTFTPRHMGTMFGAPGGDYCHGLIHPEQMGPNRPGPKGY
VDQPLPVDGLYLASAGCHGGPGITFIPGYNAARQALTDLG

Sequences:

>Translated_520_residues
MPDFDVVVIGAGHNGLTAAALLQRSGLRTVCLEAKRYAGGMASTVELFDGYRFEIAGSLQFPTSATVSRELGLDELPTVD
LEVMSVSLRGVGDAPVVYYTDPMRMLTHLDEVHGADAVAGMAGLMAWSQGPTRALGRFDADRPPRSLDEMYACAATPFER
AAITDMLFGSVSDVLDRYLPDREKHGALRGMLAFLAVNTTYRGPATPGSAAALAFGLAVPDENAALMKKLRGGIGALTDH
LCRLFTEAGGEVRLRSKVERIAVADGRVSGVALEDGTTLTAHTVVSAVAPDLTVTALLDPDAVTADLRDRFARIDHRGSY
LQMHFALDAAPTFAAPYEMLNDPELQAAIGLFSTPEELQSQWEDCRRGVVPADPAIALQIPSAHDPTLALPGKHAASAFA
LWFPVETDHARYGEMKTEMGRRVIEKITRIAPDFTDLITRHTTFTPRHMGTMFGAPGGDYCHGLIHPEQMGPNRPGPKGY
VDQPLPVDGLYLASAGCHGGPGITFIPGYNAARQALTDLG
>Mature_519_residues
PDFDVVVIGAGHNGLTAAALLQRSGLRTVCLEAKRYAGGMASTVELFDGYRFEIAGSLQFPTSATVSRELGLDELPTVDL
EVMSVSLRGVGDAPVVYYTDPMRMLTHLDEVHGADAVAGMAGLMAWSQGPTRALGRFDADRPPRSLDEMYACAATPFERA
AITDMLFGSVSDVLDRYLPDREKHGALRGMLAFLAVNTTYRGPATPGSAAALAFGLAVPDENAALMKKLRGGIGALTDHL
CRLFTEAGGEVRLRSKVERIAVADGRVSGVALEDGTTLTAHTVVSAVAPDLTVTALLDPDAVTADLRDRFARIDHRGSYL
QMHFALDAAPTFAAPYEMLNDPELQAAIGLFSTPEELQSQWEDCRRGVVPADPAIALQIPSAHDPTLALPGKHAASAFAL
WFPVETDHARYGEMKTEMGRRVIEKITRIAPDFTDLITRHTTFTPRHMGTMFGAPGGDYCHGLIHPEQMGPNRPGPKGYV
DQPLPVDGLYLASAGCHGGPGITFIPGYNAARQALTDLG

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI229577391, Length=573, Percent_Identity=29.1448516579407, Blast_Score=172, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17540238, Length=548, Percent_Identity=24.4525547445255, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 55623; Mature: 55492

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFDVVVIGAGHNGLTAAALLQRSGLRTVCLEAKRYAGGMASTVELFDGYRFEIAGSLQ
CCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCEEEEEEECEE
FPTSATVSRELGLDELPTVDLEVMSVSLRGVGDAPVVYYTDPMRMLTHLDEVHGADAVAG
CCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHHHHCCHHHHHH
MAGLMAWSQGPTRALGRFDADRPPRSLDEMYACAATPFERAAITDMLFGSVSDVLDRYLP
HHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
DREKHGALRGMLAFLAVNTTYRGPATPGSAAALAFGLAVPDENAALMKKLRGGIGALTDH
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEECCCCCCHHHHHHHHCCHHHHHHH
LCRLFTEAGGEVRLRSKVERIAVADGRVSGVALEDGTTLTAHTVVSAVAPDLTVTALLDP
HHHHHHHCCCCEEHHHHHHHHHCCCCCEEEEEECCCCEEHHHHHHHHHCCCCEEEEEECC
DAVTADLRDRFARIDHRGSYLQMHFALDAAPTFAAPYEMLNDPELQAAIGLFSTPEELQS
CHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHCCCCCHHHHHCCCCCHHHHHH
QWEDCRRGVVPADPAIALQIPSAHDPTLALPGKHAASAFALWFPVETDHARYGEMKTEMG
HHHHHHCCCCCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
RRVIEKITRIAPDFTDLITRHTTFTPRHMGTMFGAPGGDYCHGLIHPEQMGPNRPGPKGY
HHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHCCCCCCHHCCCCCCHHHCCCCCCCCCCC
VDQPLPVDGLYLASAGCHGGPGITFIPGYNAARQALTDLG
CCCCCCCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHCC
>Mature Secondary Structure 
PDFDVVVIGAGHNGLTAAALLQRSGLRTVCLEAKRYAGGMASTVELFDGYRFEIAGSLQ
CCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHCCEEEEEEECEE
FPTSATVSRELGLDELPTVDLEVMSVSLRGVGDAPVVYYTDPMRMLTHLDEVHGADAVAG
CCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHHHHHCCHHHHHH
MAGLMAWSQGPTRALGRFDADRPPRSLDEMYACAATPFERAAITDMLFGSVSDVLDRYLP
HHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
DREKHGALRGMLAFLAVNTTYRGPATPGSAAALAFGLAVPDENAALMKKLRGGIGALTDH
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEECCCCCCHHHHHHHHCCHHHHHHH
LCRLFTEAGGEVRLRSKVERIAVADGRVSGVALEDGTTLTAHTVVSAVAPDLTVTALLDP
HHHHHHHCCCCEEHHHHHHHHHCCCCCEEEEEECCCCEEHHHHHHHHHCCCCEEEEEECC
DAVTADLRDRFARIDHRGSYLQMHFALDAAPTFAAPYEMLNDPELQAAIGLFSTPEELQS
CHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHCCCCCHHHHHCCCCCHHHHHH
QWEDCRRGVVPADPAIALQIPSAHDPTLALPGKHAASAFALWFPVETDHARYGEMKTEMG
HHHHHHCCCCCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHH
RRVIEKITRIAPDFTDLITRHTTFTPRHMGTMFGAPGGDYCHGLIHPEQMGPNRPGPKGY
HHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHCCCCCCHHCCCCCCHHHCCCCCCCCCCC
VDQPLPVDGLYLASAGCHGGPGITFIPGYNAARQALTDLG
CCCCCCCCCEEEEECCCCCCCCEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2263648 [H]