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The map label for this gene is iolF [H]

Identifier: 108801355

GI number: 108801355

Start: 4669948

End: 4671267

Strand: Reverse

Name: iolF [H]

Synonym: Mmcs_4392

Alternate gene names: 108801355

Gene position: 4671267-4669948 (Counterclockwise)

Preceding gene: 108801356

Following gene: 108801354

Centisome position: 81.87

GC content: 67.88

Gene sequence:

>1320_bases
GTGAAAGTAGGAGCGCGCTCCACCACAGGCTGGAAGGCGACGATCTCGGTCGCGATGTCGAACTACATCGAGGCGGGGTC
GATCATCGCGATCGCCACCAGCCTGGGTTTCTGGCAGGCCGAGTTCGGCATCAGCAACTTCGGCGTCGGCCTGCTCGCGG
CGTTGAGCGCCAACGCCTTCGGCGCCGCGATCGGCGCGATACTCGGCGGCCCGCTGTGTGATCGGTTCGGGCGCAAGGCG
ATCTACACCTACGACCTGCTGGTCTACATGGCCGGTGTGCTGGTGGCCGCCTGCGCGGTGAACTTCACCATGCTGCTGAT
CGGGTTCATCGTCACCGGCATCGCCGTCGGGGCCGGGGTGCCTGCCTCGTGGACCTACATCGCCGAACAGGCGCCCTCGG
TGCAGCGGGCCAAACACGTCGGCACCGCGCAGCTGGCCTGGTCGACCGGGCCGCTCGTCGGGTTCGCGCTCGCGGCTGCG
CTGGCGCCGCTGGGACTGCTCGGTTCTCGGTTGATCTTCGCCCACCTGTTCGTCGTGGCGGCGATCGTGTGGTGGGTCCG
CCAGGGCCTGCAGGAATCGCAGATCTGGCAGGACGAGGGACGGGACGAGCCGACGCAGGTCGCCTCCGCGGTGGGGGTCC
GTGGGCTGCGGGGCCTGTTCTCGCGCCGGGTCAACATCACCGCGCTGCTCTTCCTCGGCGGGATCTACCTGTTCTGGAAC
ACCGTCGCCGGGCAGGCCGGAATCTTCATGCCCCGCGTGTACGACACCGCAGGCCTGCACAGCGCGGTCCAGCAGAACCT
GCTGCAGGTGCTGGTGTGGGGGTGCACGGTGCTCGCCACCTACTTCGGGTTCATGGGACTCGCCGACCGGATGTCGCAGC
GGCTGCTGTACGTCATCGGCGCCGCCCTGGGCATCGTCGGCTGGATCGTGCTGGTCGCGTTCACCGACAGCGGCGTGCCG
ACGATGCTGATCTTCGCGGTGCTGTGGGGTGTCTCCAGCGGCATCGGCGCGCAGGCGTTCTACAGCCTGTGGACCAGTGA
ACTGTTCGCCACCCCGTACCGCGCGAGCGCACAGGGCGTCATGTTCTTCGTCGTCCGCACCGCCACCGGCCTGCTGTCCT
ACTTCTTCCCGACGATGCTCGCCGTCACCGGCCTCACCGGCGTCGGGTTGCTGCTCGTCGGGCTGCTCACCATCGCACTG
GTCATCGGTGCGGTCTGGGCGCCGCAGACCCGCGGTAAGACCCTCAAACAGATCGAAGCCGAACGCTACGGCGCCCCCGT
CTCACCGGCGAACGTCGAGAAAGCAGCTGTCACACCATGA

Upstream 100 bases:

>100_bases
ACGACCGGTGGCAGGCGACCATGGCCGACTACTTCGACAACCGGCCCGATCACGCGATGGACCGACTCACCCACTATTTC
CATCTACCCTGAGGACTGCC

Downstream 100 bases:

>100_bases
ATGCCGTCCTCGACCACCTCGCGATCGAATTGCCGTCCTGGGCGTTCGGCAACTCCGGCACCCGCTTCAAGGTGTTCGGC
ACGCCCGGCACCGCCCGCAC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; L-arabinose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKVGARSTTGWKATISVAMSNYIEAGSIIAIATSLGFWQAEFGISNFGVGLLAALSANAFGAAIGAILGGPLCDRFGRKA
IYTYDLLVYMAGVLVAACAVNFTMLLIGFIVTGIAVGAGVPASWTYIAEQAPSVQRAKHVGTAQLAWSTGPLVGFALAAA
LAPLGLLGSRLIFAHLFVVAAIVWWVRQGLQESQIWQDEGRDEPTQVASAVGVRGLRGLFSRRVNITALLFLGGIYLFWN
TVAGQAGIFMPRVYDTAGLHSAVQQNLLQVLVWGCTVLATYFGFMGLADRMSQRLLYVIGAALGIVGWIVLVAFTDSGVP
TMLIFAVLWGVSSGIGAQAFYSLWTSELFATPYRASAQGVMFFVVRTATGLLSYFFPTMLAVTGLTGVGLLLVGLLTIAL
VIGAVWAPQTRGKTLKQIEAERYGAPVSPANVEKAAVTP

Sequences:

>Translated_439_residues
MKVGARSTTGWKATISVAMSNYIEAGSIIAIATSLGFWQAEFGISNFGVGLLAALSANAFGAAIGAILGGPLCDRFGRKA
IYTYDLLVYMAGVLVAACAVNFTMLLIGFIVTGIAVGAGVPASWTYIAEQAPSVQRAKHVGTAQLAWSTGPLVGFALAAA
LAPLGLLGSRLIFAHLFVVAAIVWWVRQGLQESQIWQDEGRDEPTQVASAVGVRGLRGLFSRRVNITALLFLGGIYLFWN
TVAGQAGIFMPRVYDTAGLHSAVQQNLLQVLVWGCTVLATYFGFMGLADRMSQRLLYVIGAALGIVGWIVLVAFTDSGVP
TMLIFAVLWGVSSGIGAQAFYSLWTSELFATPYRASAQGVMFFVVRTATGLLSYFFPTMLAVTGLTGVGLLLVGLLTIAL
VIGAVWAPQTRGKTLKQIEAERYGAPVSPANVEKAAVTP
>Mature_439_residues
MKVGARSTTGWKATISVAMSNYIEAGSIIAIATSLGFWQAEFGISNFGVGLLAALSANAFGAAIGAILGGPLCDRFGRKA
IYTYDLLVYMAGVLVAACAVNFTMLLIGFIVTGIAVGAGVPASWTYIAEQAPSVQRAKHVGTAQLAWSTGPLVGFALAAA
LAPLGLLGSRLIFAHLFVVAAIVWWVRQGLQESQIWQDEGRDEPTQVASAVGVRGLRGLFSRRVNITALLFLGGIYLFWN
TVAGQAGIFMPRVYDTAGLHSAVQQNLLQVLVWGCTVLATYFGFMGLADRMSQRLLYVIGAALGIVGWIVLVAFTDSGVP
TMLIFAVLWGVSSGIGAQAFYSLWTSELFATPYRASAQGVMFFVVRTATGLLSYFFPTMLAVTGLTGVGLLLVGLLTIAL
VIGAVWAPQTRGKTLKQIEAERYGAPVSPANVEKAAVTP

Specific function: Minor myo-inositol uptake transporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46320; Mature: 46320

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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HHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-arabinose [Periplasm] [C]

Specific reaction: L-arabinose = L-ribulose Proton [Periplasm] + arabinose [Periplasm] = Proton [Cytoplasm] + arabinose [Cytoplasm] [C]

General reaction: Isomerases; Intramolecular Oxidoreductases; Interconverting Aldoses and Ketoses; L-arabinose isomerase Reaction [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 1761221; 11807058 [H]