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The map label for this gene is moaB [H]

Identifier: 108801262

GI number: 108801262

Start: 4565283

End: 4565855

Strand: Reverse

Name: moaB [H]

Synonym: Mmcs_4298

Alternate gene names: 108801262

Gene position: 4565855-4565283 (Counterclockwise)

Preceding gene: 108801263

Following gene: 108801261

Centisome position: 80.03

GC content: 68.24

Gene sequence:

>573_bases
GTGACGACCGGGACCGGACCGGGAACACTGCGAGTGGCTGCGTCGCTGTCCGTGCCCACATATACGGTTGAGGTCATGGA
GCAGCCAGGGGAGTTGGTGGGCCGTGCGCTCGTCATCGTCGTCGATGACCGCACCGCCCACGGCGACGAAGAGGATCACA
GCGGTCCGTTGGTCACCGAGCTTCTCGGTGAGGCGGGTTTCGTCGTCGACGGTGTCGTGGTGGTGTCCGCTGACGAGGTG
GAGATCCGCAACGCGTTGAACACCGCCGTGATCGGCGGGGTGGACCTCGTCGTGTCGGTCGGCGGCACCGGCGTGACGCC
GCGCGACGTGACGCCGGAGGCGACGCGGGACATCCTCGACCGTGAACTCCTCGGCATCTCGGAGGCGCTGCGCGCGTCCG
GGCTGTCCGCAGGCATCGTCGACGCCGGGGTGTCGCGCGGGCTGGCCGGTATCTCGGGCAGCACCCTGGTGGTCAACATC
GCCGGATCCCGCGCGGCGGTGCGCGACGGCATGGCCACGCTGAGCCCGTTGGCCGTGCAAATCATCGGACAGCTATCAAG
TCTGGAAATCTGA

Upstream 100 bases:

>100_bases
CGGTGCGGTCCAAGGCACCCGGCGACAAGGTCACGCTGACCTATCTCGATCCGTCGGGCAAGCCGCAGAGCGTGCAGGTG
ACTCTCGGGAAGATGCAGCA

Downstream 100 bases:

>100_bases
CGTCGATTCGTCCTGGCAAGACGCCGCGGCGACGCCCTCACAGCGTCGCCTCGGCGTCTTCTTCGTTTGCGCCCGTTACG
GCGACTGTCTGCAGTGTTAC

Product: molybdopterin binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MTTGTGPGTLRVAASLSVPTYTVEVMEQPGELVGRALVIVVDDRTAHGDEEDHSGPLVTELLGEAGFVVDGVVVVSADEV
EIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILDRELLGISEALRASGLSAGIVDAGVSRGLAGISGSTLVVNI
AGSRAAVRDGMATLSPLAVQIIGQLSSLEI

Sequences:

>Translated_190_residues
MTTGTGPGTLRVAASLSVPTYTVEVMEQPGELVGRALVIVVDDRTAHGDEEDHSGPLVTELLGEAGFVVDGVVVVSADEV
EIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILDRELLGISEALRASGLSAGIVDAGVSRGLAGISGSTLVVNI
AGSRAAVRDGMATLSPLAVQIIGQLSSLEI
>Mature_189_residues
TTGTGPGTLRVAASLSVPTYTVEVMEQPGELVGRALVIVVDDRTAHGDEEDHSGPLVTELLGEAGFVVDGVVVVSADEVE
IRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILDRELLGISEALRASGLSAGIVDAGVSRGLAGISGSTLVVNIA
GSRAAVRDGMATLSPLAVQIIGQLSSLEI

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=146, Percent_Identity=29.4520547945205, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI66932975, Length=146, Percent_Identity=29.4520547945205, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564954, Length=148, Percent_Identity=39.1891891891892, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17136978, Length=159, Percent_Identity=35.8490566037736, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24638841, Length=159, Percent_Identity=35.8490566037736, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19163; Mature: 19032

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGTGPGTLRVAASLSVPTYTVEVMEQPGELVGRALVIVVDDRTAHGDEEDHSGPLVTE
CCCCCCCCEEEEEEECCCCEEEEEEHHCCHHHHCEEEEEEEECCCCCCCCCCCCCCHHHH
LLGEAGFVVDGVVVVSADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILD
HHCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
RELLGISEALRASGLSAGIVDAGVSRGLAGISGSTLVVNIAGSRAAVRDGMATLSPLAVQ
HHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHHH
IIGQLSSLEI
HHHHHHHCCC
>Mature Secondary Structure 
TTGTGPGTLRVAASLSVPTYTVEVMEQPGELVGRALVIVVDDRTAHGDEEDHSGPLVTE
CCCCCCCEEEEEEECCCCEEEEEEHHCCHHHHCEEEEEEEECCCCCCCCCCCCCCHHHH
LLGEAGFVVDGVVVVSADEVEIRNALNTAVIGGVDLVVSVGGTGVTPRDVTPEATRDILD
HHCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHH
RELLGISEALRASGLSAGIVDAGVSRGLAGISGSTLVVNIAGSRAAVRDGMATLSPLAVQ
HHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHHH
IIGQLSSLEI
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]