Click here to switch to the map view.

The map label for this gene is degQ [C]

Identifier: 108801263

GI number: 108801263

Start: 4565852

End: 4567174

Strand: Reverse

Name: degQ [C]

Synonym: Mmcs_4299

Alternate gene names: 108801263

Gene position: 4567174-4565852 (Counterclockwise)

Preceding gene: 108801264

Following gene: 108801262

Centisome position: 80.05

GC content: 69.99

Gene sequence:

>1323_bases
ATGACGAACCACCCGAGGTATTCGACGCCGCCGCAACAACAGCCGGGTCACCGCCCGGTCGGCCCGGACACGGGGTATCA
GGGCGCGGACCCCTATTCGCAGCAGCAGCCCTACGACTGGCGGTACGCGGCGCAACCGCAGCAGCAGTTCCGCGCGCCGT
ATGACCCCTACCGGGGCGCCGCCCAGCCGACCGCTGTGATGCCGCAGCCGCGCCCGACACAAAAGCGTTCGCGCGCAGGC
GCATTGACGGTCGGCGCCTTGGCGGTGGCCGTGGTGTCGGCGGGTATCGGTGGCGGTGTGGCGACGATGGTCCAGCAGGA
CCGCCCGTCCTTCGGCAGCTCTATCACGGGTGCGGCGCCGAGCGTGCCCGCCGCCGCGCTGCCCGCGGGCTCGGTGGAGC
AGGTGGCCGCCAAGGTGGTGCCGAGTGTGGTGAAGCTGGAGACGAACCTGGGCCGGGCGTCGGAGGAGGGTTCGGGCATC
ATCCTCACCTCCGACGGTCTGATCCTGACGAACAATCACGTCGTGGCCGCGGCCGCCGACGGTCCCGGGGCCCCCGGCGG
CGCTCAGACCAAGGTGATCCTCTCCGACGGCCGCACCACGTCGTTCACCGTCGTCGGCACCGATCCCAGCAGCGACATCG
CGGTGGTCCGAGCCGAGAAGGTCTCGGGCCTGACGCCGATCACGCTGGGTTCGTCGAGCGATCTGCGCGTCGGTCAGGAC
GTGGTCGCGATCGGTTCGCCGCTCGGGCTCGAGGGGACGGTCACCACCGGCATCATCAGCGCGCTGAACCGGCCGGTCGC
CGCCGGCGGCGATACGCGCAACCAGAACACGGTTCTCGACGCCATCCAGACCGACGCCGCGATCAACCCCGGTAACTCGG
GTGGTGCGCTGGTGAACATGAACGGTGAGCTGGTCGGCGTGAACTCGGCCATCGCCACCATGGGCGGTGACTCGGCGCAG
GCGCAGAGCGGTTCGATCGGTCTCGGCTTCGCGATCCCCGTGGATCAGGCCAAGCGCATCGCCGACGAGTTGATCCAGAA
CGGCAGCGCCTCACACGCGTCGCTCGGGGTGCAGGTCAGCAACGACGCCGCGACCGACGGCGCGAAGATCGTCGAGGTCA
ACCAGGGTGGCGCCGCGGCGGCGGCGGGTCTGCCCAGCGGCGTGGTGGTGACCAAGGTCGACGACCGGGTGATCAACAGC
GCCGATGCGCTCGTGGCGGCGGTGCGGTCCAAGGCACCCGGCGACAAGGTCACGCTGACCTATCTCGATCCGTCGGGCAA
GCCGCAGAGCGTGCAGGTGACTCTCGGGAAGATGCAGCAGTGA

Upstream 100 bases:

>100_bases
AGGAACTCTAAGTGGATTCTCAGTCCATCTGGGCACTGTGAGGACAAGTACTTCGTTAAACGAACTGTCGGACCACTCAC
CAGGAGAGCATCGAAGCGAC

Downstream 100 bases:

>100_bases
CGACCGGGACCGGACCGGGAACACTGCGAGTGGCTGCGTCGCTGTCCGTGCCCACATATACGGTTGAGGTCATGGAGCAG
CCAGGGGAGTTGGTGGGCCG

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTNHPRYSTPPQQQPGHRPVGPDTGYQGADPYSQQQPYDWRYAAQPQQQFRAPYDPYRGAAQPTAVMPQPRPTQKRSRAG
ALTVGALAVAVVSAGIGGGVATMVQQDRPSFGSSITGAAPSVPAAALPAGSVEQVAAKVVPSVVKLETNLGRASEEGSGI
ILTSDGLILTNNHVVAAAADGPGAPGGAQTKVILSDGRTTSFTVVGTDPSSDIAVVRAEKVSGLTPITLGSSSDLRVGQD
VVAIGSPLGLEGTVTTGIISALNRPVAAGGDTRNQNTVLDAIQTDAAINPGNSGGALVNMNGELVGVNSAIATMGGDSAQ
AQSGSIGLGFAIPVDQAKRIADELIQNGSASHASLGVQVSNDAATDGAKIVEVNQGGAAAAAGLPSGVVVTKVDDRVINS
ADALVAAVRSKAPGDKVTLTYLDPSGKPQSVQVTLGKMQQ

Sequences:

>Translated_440_residues
MTNHPRYSTPPQQQPGHRPVGPDTGYQGADPYSQQQPYDWRYAAQPQQQFRAPYDPYRGAAQPTAVMPQPRPTQKRSRAG
ALTVGALAVAVVSAGIGGGVATMVQQDRPSFGSSITGAAPSVPAAALPAGSVEQVAAKVVPSVVKLETNLGRASEEGSGI
ILTSDGLILTNNHVVAAAADGPGAPGGAQTKVILSDGRTTSFTVVGTDPSSDIAVVRAEKVSGLTPITLGSSSDLRVGQD
VVAIGSPLGLEGTVTTGIISALNRPVAAGGDTRNQNTVLDAIQTDAAINPGNSGGALVNMNGELVGVNSAIATMGGDSAQ
AQSGSIGLGFAIPVDQAKRIADELIQNGSASHASLGVQVSNDAATDGAKIVEVNQGGAAAAAGLPSGVVVTKVDDRVINS
ADALVAAVRSKAPGDKVTLTYLDPSGKPQSVQVTLGKMQQ
>Mature_439_residues
TNHPRYSTPPQQQPGHRPVGPDTGYQGADPYSQQQPYDWRYAAQPQQQFRAPYDPYRGAAQPTAVMPQPRPTQKRSRAGA
LTVGALAVAVVSAGIGGGVATMVQQDRPSFGSSITGAAPSVPAAALPAGSVEQVAAKVVPSVVKLETNLGRASEEGSGII
LTSDGLILTNNHVVAAAADGPGAPGGAQTKVILSDGRTTSFTVVGTDPSSDIAVVRAEKVSGLTPITLGSSSDLRVGQDV
VAIGSPLGLEGTVTTGIISALNRPVAAGGDTRNQNTVLDAIQTDAAINPGNSGGALVNMNGELVGVNSAIATMGGDSAQA
QSGSIGLGFAIPVDQAKRIADELIQNGSASHASLGVQVSNDAATDGAKIVEVNQGGAAAAAGLPSGVVVTKVDDRVINSA
DALVAAVRSKAPGDKVTLTYLDPSGKPQSVQVTLGKMQQ

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=307, Percent_Identity=33.5504885993485, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4506141, Length=219, Percent_Identity=38.8127853881278, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI24308541, Length=305, Percent_Identity=32.1311475409836, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7019477, Length=314, Percent_Identity=32.8025477707006, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1789629, Length=290, Percent_Identity=40, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1786356, Length=295, Percent_Identity=40.3389830508475, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1789630, Length=289, Percent_Identity=34.2560553633218, Blast_Score=115, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24646839, Length=292, Percent_Identity=36.6438356164384, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 44208; Mature: 44077

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNHPRYSTPPQQQPGHRPVGPDTGYQGADPYSQQQPYDWRYAAQPQQQFRAPYDPYRGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHCCCCCCCCCC
AQPTAVMPQPRPTQKRSRAGALTVGALAVAVVSAGIGGGVATMVQQDRPSFGSSITGAAP
CCCCEECCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCC
SVPAAALPAGSVEQVAAKVVPSVVKLETNLGRASEEGSGIILTSDGLILTNNHVVAAAAD
CCCHHHCCCCCHHHHHHHHCCHHEEEECCCCCCCCCCCEEEEECCCEEEECCEEEEEECC
GPGAPGGAQTKVILSDGRTTSFTVVGTDPSSDIAVVRAEKVSGLTPITLGSSSDLRVGQD
CCCCCCCCEEEEEEECCCEEEEEEEECCCCCCEEEEEEHHHCCCCEEEECCCCCCCCCCE
VVAIGSPLGLEGTVTTGIISALNRPVAAGGDTRNQNTVLDAIQTDAAINPGNSGGALVNM
EEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEC
NGELVGVNSAIATMGGDSAQAQSGSIGLGFAIPVDQAKRIADELIQNGSASHASLGVQVS
CCCEEECCHHEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEEC
NDAATDGAKIVEVNQGGAAAAAGLPSGVVVTKVDDRVINSADALVAAVRSKAPGDKVTLT
CCCCCCCEEEEEECCCCCHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEE
YLDPSGKPQSVQVTLGKMQQ
EECCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TNHPRYSTPPQQQPGHRPVGPDTGYQGADPYSQQQPYDWRYAAQPQQQFRAPYDPYRGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHCCCCCCCCCC
AQPTAVMPQPRPTQKRSRAGALTVGALAVAVVSAGIGGGVATMVQQDRPSFGSSITGAAP
CCCCEECCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCC
SVPAAALPAGSVEQVAAKVVPSVVKLETNLGRASEEGSGIILTSDGLILTNNHVVAAAAD
CCCHHHCCCCCHHHHHHHHCCHHEEEECCCCCCCCCCCEEEEECCCEEEECCEEEEEECC
GPGAPGGAQTKVILSDGRTTSFTVVGTDPSSDIAVVRAEKVSGLTPITLGSSSDLRVGQD
CCCCCCCCEEEEEEECCCEEEEEEEECCCCCCEEEEEEHHHCCCCEEEECCCCCCCCCCE
VVAIGSPLGLEGTVTTGIISALNRPVAAGGDTRNQNTVLDAIQTDAAINPGNSGGALVNM
EEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEC
NGELVGVNSAIATMGGDSAQAQSGSIGLGFAIPVDQAKRIADELIQNGSASHASLGVQVS
CCCEEECCHHEEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEEC
NDAATDGAKIVEVNQGGAAAAAGLPSGVVVTKVDDRVINSADALVAAVRSKAPGDKVTLT
CCCCCCCEEEEEECCCCCHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEE
YLDPSGKPQSVQVTLGKMQQ
EECCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]