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The map label for this gene is 108801178

Identifier: 108801178

GI number: 108801178

Start: 4473338

End: 4474276

Strand: Reverse

Name: 108801178

Synonym: Mmcs_4214

Alternate gene names: NA

Gene position: 4474276-4473338 (Counterclockwise)

Preceding gene: 108801179

Following gene: 108801177

Centisome position: 78.42

GC content: 65.39

Gene sequence:

>939_bases
ATGACCAGGACACGCTCGGACTCGCTCGCCGCCGGTGGGCTGAACTGGAACAGCATGCCGCTCAAGCTCTTCGCCGGTGG
CAACGCGAAGTTCTGGGACCCCGCGGACATCGACTTCTCCCGCGACCGCGCTGACTGGGAGTCGCTGTCGAACCTCGAGC
GCGACTGGGCCACCCGCCTGTGCGCCCAGTTCATCGCCGGTGAGGAGGCGGTCACCCAGGACATCCAGCCGTTCATGGCG
GCGATGCGCGCCGAGGGCCGGCTCGGTGACGAGATGTACCTGACGCAGTTCGCGTTCGAGGAGGCCAAGCACACGCAGGT
GTTCCGCATGTGGCTCGACGCGGTCGGGATGACCGACGACCTCCAGTGCTACCTCGACGACCTGCCGTCCTACCGGCAGA
TGTTCTACGAGGAACTGCCCGCATCGTTGGAGGCCCTGGCCACCGACCCGTCGCCGGCGGCTCAGGTGCGCGCGTCCGCG
ACCTACAACCACGTCATCGAGGGTATGATGGCCTTGACGGGATACTATGCCTGGCACCGGATTTGCGTAGATCGAAAGGT
GCTGCCGGGTATGCAGGAGCTGGTCCGCCGCATCGGTGACGACGAGCGTCGGCATATGGCGTGGGGTACCTTCACCTGCC
GGCGGCACGTCGCGGCCGACGACGCGAACTGGGAAGTGTTCGAGAACCGGATGAACGAGCTGATCCCTCTCGCGCTCAGC
AACACCGACGATTCCTTCGCGCTGTACGACGAAATTCCGTTCGGCTTCGCGAAGGAGGAGTTTCAGCAGTACGCCGCCGA
CAAGGGCATGCGCCGGTTCGGCACCATCAGCAGCGCTCGCGGCCGCGCCCTGGCAGAGATCGACGTCGACTACTCACCGT
TGCAGTTGGAGGACACCTTCGCTGCGGAGGACAGTCGAGTGCTGGCCACGTCTGCCTGA

Upstream 100 bases:

>100_bases
CGGCCCTGGCCGTGCGCCGATACGTCGCCGTGTTGTCGGCGGCCTTCCAAACCGTCCCGGTGCAGCCCACACGGGATTCG
ATCGCGCAGGAGGTAACACC

Downstream 100 bases:

>100_bases
CCTCACGCTCGCCGGGCTCCGGCCGTCGGCCGGTCGCCCCGAGTCTGGGCTGCGCTTGTCGTGCAATCCCCATCGGATAC
GACGGCTGACCATACATACT

Product: ribonucleotide-diphosphate reductase subunit beta

Products: ribonucleoside diphosphate; thioredoxin

Alternate protein names: Ribonucleotide reductase R2 subunit homolog; Ribonucleotide reductase small subunit homolog [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTRTRSDSLAAGGLNWNSMPLKLFAGGNAKFWDPADIDFSRDRADWESLSNLERDWATRLCAQFIAGEEAVTQDIQPFMA
AMRAEGRLGDEMYLTQFAFEEAKHTQVFRMWLDAVGMTDDLQCYLDDLPSYRQMFYEELPASLEALATDPSPAAQVRASA
TYNHVIEGMMALTGYYAWHRICVDRKVLPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWEVFENRMNELIPLALS
NTDDSFALYDEIPFGFAKEEFQQYAADKGMRRFGTISSARGRALAEIDVDYSPLQLEDTFAAEDSRVLATSA

Sequences:

>Translated_312_residues
MTRTRSDSLAAGGLNWNSMPLKLFAGGNAKFWDPADIDFSRDRADWESLSNLERDWATRLCAQFIAGEEAVTQDIQPFMA
AMRAEGRLGDEMYLTQFAFEEAKHTQVFRMWLDAVGMTDDLQCYLDDLPSYRQMFYEELPASLEALATDPSPAAQVRASA
TYNHVIEGMMALTGYYAWHRICVDRKVLPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWEVFENRMNELIPLALS
NTDDSFALYDEIPFGFAKEEFQQYAADKGMRRFGTISSARGRALAEIDVDYSPLQLEDTFAAEDSRVLATSA
>Mature_311_residues
TRTRSDSLAAGGLNWNSMPLKLFAGGNAKFWDPADIDFSRDRADWESLSNLERDWATRLCAQFIAGEEAVTQDIQPFMAA
MRAEGRLGDEMYLTQFAFEEAKHTQVFRMWLDAVGMTDDLQCYLDDLPSYRQMFYEELPASLEALATDPSPAAQVRASAT
YNHVIEGMMALTGYYAWHRICVDRKVLPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWEVFENRMNELIPLALSN
TDDSFALYDEIPFGFAKEEFQQYAADKGMRRFGTISSARGRALAEIDVDYSPLQLEDTFAAEDSRVLATSA

Specific function: Probable oxidase that might be involved in lipid metabolism [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: 1.17.4.1

Molecular weight: Translated: 35434; Mature: 35303

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTRSDSLAAGGLNWNSMPLKLFAGGNAKFWDPADIDFSRDRADWESLSNLERDWATRL
CCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
CAQFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHTQVFRMWLDAVGMTDD
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LQCYLDDLPSYRQMFYEELPASLEALATDPSPAAQVRASATYNHVIEGMMALTGYYAWHR
HHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICVDRKVLPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWEVFENRMNELIPLALS
HHHCCHHCCCHHHHHHHHCCCHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEEC
NTDDSFALYDEIPFGFAKEEFQQYAADKGMRRFGTISSARGRALAEIDVDYSPLQLEDTF
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCCEECCCC
AAEDSRVLATSA
CCCCCEEEEECC
>Mature Secondary Structure 
TRTRSDSLAAGGLNWNSMPLKLFAGGNAKFWDPADIDFSRDRADWESLSNLERDWATRL
CCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
CAQFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHTQVFRMWLDAVGMTDD
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LQCYLDDLPSYRQMFYEELPASLEALATDPSPAAQVRASATYNHVIEGMMALTGYYAWHR
HHHHHHCCHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICVDRKVLPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWEVFENRMNELIPLALS
HHHCCHHCCCHHHHHHHHCCCHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEEC
NTDDSFALYDEIPFGFAKEEFQQYAADKGMRRFGTISSARGRALAEIDVDYSPLQLEDTF
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCCEECCCC
AAEDSRVLATSA
CCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside diphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA