| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is fabG [H]
Identifier: 108801177
GI number: 108801177
Start: 4472378
End: 4473169
Strand: Reverse
Name: fabG [H]
Synonym: Mmcs_4213
Alternate gene names: 108801177
Gene position: 4473169-4472378 (Counterclockwise)
Preceding gene: 108801178
Following gene: 108801175
Centisome position: 78.4
GC content: 68.69
Gene sequence:
>792_bases GTGAACAGGTTTGACGGCAAGGGTGTCCTGGTGACCGGAGCGGCGTCGGGAATCGGGCAGGCGACGGTGCAACGACTCCT GGAGGAAGGGGCCTACGTCGTCGGGCTGGACCTTCCCGAGGCTGATCGCGTCGCCGATCGATACGCCTACCGCCGCGCCG ACATCCTGGACGCAGAAGCCGTCGCCGACGCGCTGGCCGCCGTGGTGGCCGGGGCCGGTCGCCTCGACGGTGTGGTGCAC TCCGCCGGGGTGGCAGGCGGAGGACCCATCCACCTGCTGCCCGACGAAGAATGGGACCGCGTGGTCGACGTCAACCTCAA GGGCACCTTCGTCGTCAACCGCGCCGCGCTGACCCAGATGCTGCAGCAGGACCGTGTCGACGGCGAACGCGGCGCGATCG TCAACCTGTCCAGCATCGAGGGGCTGGAGGGCACTGCGGGCGGCAGCTCCTACAACGCCTCGAAGGGCGGAGTCGTGCTG CTGACCAAGAACGCGGCAATCGACTACGGGCCGAGCGGGATTCGGGTCAACGCGATCTGTCCCGGCTTCATCGAGACACC GCTGTTCGACGCCGTTGTCGGCATGCCCGGCATGGAGCGACCGCGCGAGGGCCTACGTCACGAGCACAAGCTGCGACGGT TCGGCCGAGCGACCGAGGTGGCCGGCGTCGCCGCCTTCCTGCTCTCGGCGGACGCCAGCTTCGTCAGCGGGCAGACGCTG GTGGTGGACGGCGGTTACCTGGCCGGCCGTGATCATCACGTCACCGAACTGATGGGGTTGAGCGAGCAGTAG
Upstream 100 bases:
>100_bases CCCATCGGATACGACGGCTGACCATACATACTGGGCCCACTGGATGGTCAATGTCAGCGGCAGACTTTGTCGCCGTATGC GGTCGCGAAACGGGTGGCGA
Downstream 100 bases:
>100_bases TCCGCTCCTCCTGACTGGCTGTCATCGCCCAGCGAATCCCACCGACCAGCACCCGTCCGGATACCCGCACAGCAGTCGCC TCGAGAGGCGGAAAGTACGG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 263; Mature: 263
Protein sequence:
>263_residues MNRFDGKGVLVTGAASGIGQATVQRLLEEGAYVVGLDLPEADRVADRYAYRRADILDAEAVADALAAVVAGAGRLDGVVH SAGVAGGGPIHLLPDEEWDRVVDVNLKGTFVVNRAALTQMLQQDRVDGERGAIVNLSSIEGLEGTAGGSSYNASKGGVVL LTKNAAIDYGPSGIRVNAICPGFIETPLFDAVVGMPGMERPREGLRHEHKLRRFGRATEVAGVAAFLLSADASFVSGQTL VVDGGYLAGRDHHVTELMGLSEQ
Sequences:
>Translated_263_residues MNRFDGKGVLVTGAASGIGQATVQRLLEEGAYVVGLDLPEADRVADRYAYRRADILDAEAVADALAAVVAGAGRLDGVVH SAGVAGGGPIHLLPDEEWDRVVDVNLKGTFVVNRAALTQMLQQDRVDGERGAIVNLSSIEGLEGTAGGSSYNASKGGVVL LTKNAAIDYGPSGIRVNAICPGFIETPLFDAVVGMPGMERPREGLRHEHKLRRFGRATEVAGVAAFLLSADASFVSGQTL VVDGGYLAGRDHHVTELMGLSEQ >Mature_263_residues MNRFDGKGVLVTGAASGIGQATVQRLLEEGAYVVGLDLPEADRVADRYAYRRADILDAEAVADALAAVVAGAGRLDGVVH SAGVAGGGPIHLLPDEEWDRVVDVNLKGTFVVNRAALTQMLQQDRVDGERGAIVNLSSIEGLEGTAGGSSYNASKGGVVL LTKNAAIDYGPSGIRVNAICPGFIETPLFDAVVGMPGMERPREGLRHEHKLRRFGRATEVAGVAAFLLSADASFVSGQTL VVDGGYLAGRDHHVTELMGLSEQ
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=36.0902255639098, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI4758504, Length=198, Percent_Identity=39.3939393939394, Blast_Score=118, Evalue=7e-27, Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=31.0756972111554, Blast_Score=112, Evalue=5e-25, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=32.4324324324324, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=32.295719844358, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI83715985, Length=180, Percent_Identity=38.3333333333333, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=31.8181818181818, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=33.4677419354839, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI31542939, Length=223, Percent_Identity=32.2869955156951, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI59889578, Length=200, Percent_Identity=33.5, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=29.4573643410853, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI126723750, Length=267, Percent_Identity=29.5880149812734, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=34.020618556701, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=33.5260115606936, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI33667109, Length=213, Percent_Identity=31.4553990610329, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4503301, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=35.0194552529183, Blast_Score=142, Evalue=2e-35, Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=31.8725099601594, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=32.2709163346614, Blast_Score=102, Evalue=4e-23, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=29.0836653386454, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=29.8804780876494, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=29.6, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=33.6, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=31.6205533596838, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=32.1285140562249, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=31.1475409836066, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1789057, Length=180, Percent_Identity=30, Blast_Score=72, Evalue=3e-14, Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=33.4661354581673, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=33.4661354581673, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=32.9411764705882, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17538182, Length=194, Percent_Identity=36.0824742268041, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=33.0708661417323, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=28.968253968254, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562906, Length=273, Percent_Identity=29.6703296703297, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17559104, Length=281, Percent_Identity=30.2491103202847, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562990, Length=297, Percent_Identity=30.3030303030303, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=30.1158301158301, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17560150, Length=285, Percent_Identity=29.4736842105263, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560332, Length=291, Percent_Identity=29.8969072164948, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17562908, Length=294, Percent_Identity=29.9319727891156, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=29.2, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=30.3370786516854, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17562904, Length=291, Percent_Identity=28.1786941580756, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=26.7924528301887, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17531453, Length=282, Percent_Identity=28.7234042553192, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17565030, Length=275, Percent_Identity=30.9090909090909, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=30, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI193204405, Length=294, Percent_Identity=27.891156462585, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=29.8507462686567, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=26.2626262626263, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=27.9850746268657, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=26.2773722627737, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17564282, Length=203, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193203117, Length=201, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=28.6821705426357, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=29.7297297297297, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=29.0816326530612, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6320089, Length=191, Percent_Identity=24.6073298429319, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=37.5, Blast_Score=134, Evalue=8e-32, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=36.5461847389558, Blast_Score=128, Evalue=4e-30, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=33.6065573770492, Blast_Score=112, Evalue=4e-25, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=32.3076923076923, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=33.0769230769231, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=34.4961240310078, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=32.3076923076923, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI17737361, Length=251, Percent_Identity=33.0677290836653, Blast_Score=107, Evalue=9e-24, Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=38.7640449438202, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=31.2820512820513, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24665264, Length=200, Percent_Identity=31, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24665268, Length=214, Percent_Identity=30.3738317757009, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27475; Mature: 27475
Theoretical pI: Translated: 4.87; Mature: 4.87
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRFDGKGVLVTGAASGIGQATVQRLLEEGAYVVGLDLPEADRVADRYAYRRADILDAEA CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHH VADALAAVVAGAGRLDGVVHSAGVAGGGPIHLLPDEEWDRVVDVNLKGTFVVNRAALTQM HHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCEEEECHHHHHHH LQQDRVDGERGAIVNLSSIEGLEGTAGGSSYNASKGGVVLLTKNAAIDYGPSGIRVNAIC HHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEECCCCEEEEEEC PGFIETPLFDAVVGMPGMERPREGLRHEHKLRRFGRATEVAGVAAFLLSADASFVSGQTL CCHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHCCCEE VVDGGYLAGRDHHVTELMGLSEQ EEECCEECCCCCHHHHHHCCCCC >Mature Secondary Structure MNRFDGKGVLVTGAASGIGQATVQRLLEEGAYVVGLDLPEADRVADRYAYRRADILDAEA CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHH VADALAAVVAGAGRLDGVVHSAGVAGGGPIHLLPDEEWDRVVDVNLKGTFVVNRAALTQM HHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEECCCEEEECHHHHHHH LQQDRVDGERGAIVNLSSIEGLEGTAGGSSYNASKGGVVLLTKNAAIDYGPSGIRVNAIC HHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEECCCCEEEEEEC PGFIETPLFDAVVGMPGMERPREGLRHEHKLRRFGRATEVAGVAAFLLSADASFVSGQTL CCHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHCCCEE VVDGGYLAGRDHHVTELMGLSEQ EEECCEECCCCCHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]